Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P93208

Entry ID Method Resolution Chain Position Source
AF-P93208-F1 Predicted AlphaFoldDB

No variants for P93208

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P93208

No associated diseases with P93208

20 regional properties for P93208

Type Name Position InterPro Accession
domain Leucine-rich repeat N-terminal domain 46 - 80 IPR000372
repeat Leucine-rich repeat 125 - 146 IPR001611-1
repeat Leucine-rich repeat 149 - 170 IPR001611-2
repeat Leucine-rich repeat 198 - 219 IPR001611-3
repeat Leucine-rich repeat 220 - 241 IPR001611-4
repeat Leucine-rich repeat 245 - 302 IPR001611-5
repeat Leucine-rich repeat, typical subtype 79 - 98 IPR003591-1
repeat Leucine-rich repeat, typical subtype 99 - 122 IPR003591-2
repeat Leucine-rich repeat, typical subtype 123 - 146 IPR003591-3
repeat Leucine-rich repeat, typical subtype 147 - 170 IPR003591-4
repeat Leucine-rich repeat, typical subtype 196 - 217 IPR003591-5
repeat Leucine-rich repeat, typical subtype 218 - 241 IPR003591-6
repeat Leucine-rich repeat, typical subtype 242 - 265 IPR003591-7
repeat Leucine-rich repeat, typical subtype 266 - 289 IPR003591-8
domain Immunoglobulin subtype 2 366 - 433 IPR003598
domain Immunoglobulin subtype 360 - 444 IPR003599
domain Immunoglobulin-like domain 354 - 442 IPR007110
domain Immunoglobulin I-set 354 - 443 IPR013098
domain Immunoglobulin V-set domain 370 - 428 IPR013106
repeat BspA type Leucine rich repeat region 90 - 205 IPR026906

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
protein localization Any process in which a protein is transported to, or maintained in, a specific location.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

37 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q04917 YWHAH 14-3-3 protein eta Homo sapiens (Human) PR
P61981 YWHAG 14-3-3 protein gamma Homo sapiens (Human) PR
P31946 YWHAB 14-3-3 protein beta/alpha Homo sapiens (Human) PR
P27348 YWHAQ 14-3-3 protein theta Homo sapiens (Human) PR
P63104 YWHAZ 14-3-3 protein zeta/delta Homo sapiens (Human) PR
P49106 GRF1 14-3-3-like protein GF14-6 Zea mays (Maize) PR
P68510 Ywhah 14-3-3 protein eta Mus musculus (Mouse) PR
P63101 Ywhaz 14-3-3 protein zeta/delta Mus musculus (Mouse) PR
P93784 HOX 14-3-3-like protein 16R Solanum tuberosum (Potato) PR
Q41418 14-3-3-like protein Solanum tuberosum (Potato) PR
P63102 Ywhaz 14-3-3 protein zeta/delta Rattus norvegicus (Rat) PR
Q6EUP4 GF14E 14-3-3-like protein GF14-E Oryza sativa subsp japonica (Rice) PR
Q7XTE8 GF14B 14-3-3-like protein GF14-B Oryza sativa subsp japonica (Rice) PR
Q6ZKC0 GF14C 14-3-3-like protein GF14-C Oryza sativa subsp japonica (Rice) PR
Q84J55 GF14A 14-3-3-like protein GF14-A Oryza sativa subsp japonica (Rice) PR
Q2R2W2 GF14D 14-3-3-like protein GF14-D Oryza sativa subsp japonica (Rice) PR
Q06967 GF14F 14-3-3-like protein GF14-F Oryza sativa subsp japonica (Rice) PR
Q96452 GF14C 14-3-3-like protein C Glycine max (Soybean) (Glycine hispida) PR
Q96453 GF14D 14-3-3-like protein D Glycine max (Soybean) (Glycine hispida) PR
Q96450 GF14A 14-3-3-like protein A Glycine max (Soybean) (Glycine hispida) PR
Q9C5W6 GRF12 14-3-3-like protein GF14 iota Arabidopsis thaliana (Mouse-ear cress) PR
Q9S9Z8 GRF11 14-3-3-like protein GF14 omicron Arabidopsis thaliana (Mouse-ear cress) PR
Q96299 GRF9 14-3-3-like protein GF14 mu Arabidopsis thaliana (Mouse-ear cress) PR
Q96300 GRF7 14-3-3-like protein GF14 nu Arabidopsis thaliana (Mouse-ear cress) PR
P42645 GRF5 14-3-3-like protein GF14 upsilon Arabidopsis thaliana (Mouse-ear cress) PR
P42644 GRF3 14-3-3-like protein GF14 psi Arabidopsis thaliana (Mouse-ear cress) PR
P46077 GRF4 14-3-3-like protein GF14 phi Arabidopsis thaliana (Mouse-ear cress) PR
Q01525 GRF2 14-3-3-like protein GF14 omega Arabidopsis thaliana (Mouse-ear cress) PR
P42643 GRF1 14-3-3-like protein GF14 chi Arabidopsis thaliana (Mouse-ear cress) PR
P42652 TFT4 14-3-3 protein 4 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93206 TFT1 14-3-3 protein 1 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93207 TFT10 14-3-3 protein 10 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93209 TFT3 14-3-3 protein 3 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93211 TFT6 14-3-3 protein 6 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93212 TFT7 14-3-3 protein 7 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93213 TFT8 14-3-3 protein 8 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
P93214 TFT9 14-3-3 protein 9 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MAREENVYMA KLAEQAERYE EMVQFMEKVS TSLGSEELTV EERNLLSVAY KNVIGARRAS
70 80 90 100 110 120
WRIISSIEQK EESRGNEEHV KCIKEYRSKI ESELSDICDG ILKLLDSNLI PSASNGDSKV
130 140 150 160 170 180
FYLKMKGDYH RYLAEFKTGA ERKEAAESTL SAYKAAQDIA NTELAPTHPI RLGLALNFSV
190 200 210 220 230 240
FYYEILNSPD RACNLAKQAF DEAIAELDTL GEESYKDSTL IMQLLRDNLT LWTSDMQDDG
250
ADEIKETKND NEQQ