P77173
Gene name |
zipA |
Protein name |
Cell division protein ZipA |
Names |
FtsZ interacting protein A |
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b2412 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
9 structures for P77173
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1F46 | X-ray | 150 A | A/B | 189-328 | PDB |
| 1F47 | X-ray | 195 A | B | 185-328 | PDB |
| 1F7W | NMR | - | A | 185-328 | PDB |
| 1F7X | NMR | - | A | 185-328 | PDB |
| 1S1J | X-ray | 218 A | A/B | 185-328 | PDB |
| 1S1S | X-ray | 210 A | A/B | 185-328 | PDB |
| 1Y2F | X-ray | 200 A | A | 190-328 | PDB |
| 1Y2G | X-ray | 190 A | A/B | 189-328 | PDB |
| AF-P77173-F1 | Predicted | AlphaFoldDB |
No variants for P77173
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P77173 | |||||
No associated diseases with P77173
1 regional properties for P77173
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ZipA, C-terminal FtsZ-binding domain | 191 - 320 | IPR007449 |
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell division site | The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles. |
| divisome complex | A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| division septum assembly | The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material. |
| FtsZ-dependent cytokinesis | A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMQDLRLILI | IVGAIAIIAL | LVHGFWTSRK | ERSSMFRDRP | LKRMKSKRDD | DSYDEDVEDD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EGVGEVRVHR | VNHAPANAQE | HEAARPSPQH | QYQPPYASAQ | PRQPVQQPPE | AQVPPQHAPH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PAQPVQQPAY | QPQPEQPLQQ | PVSPQVAPAP | QPVHSAPQPA | QQAFQPAEPV | AAPQPEPVAE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PAPVMDKPKR | KEAVIIMNVA | AHHGSELNGE | LLLNSIQQAG | FIFGDMNIYH | RHLSPDGSGP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALFSLANMVK | PGTFDPEMKD | FTTPGVTIFM | QVPSYGDELQ | NFKLMLQSAQ | HIADEVGGVV |
| 310 | 320 | ||||
| LDDQRRMMTP | QKLREYQDII | REVKDANA |