P68640

PR
Gene name
yopN (lcrE)
Protein name
Outer membrane protein YopN
Names
LcrE, Yop4b
Species
Yersinia pestis
KEGG Pathway
ypm:YP_pCD44
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-141 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P68640

Entry ID Method Resolution Chain Position Source
1XKP X-ray 170 A A 33-277 PDB
1XL3 X-ray 220 A A/B 76-293 PDB
AF-P68640-F1 Predicted AlphaFoldDB

No variants for P68640

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P68640

No associated diseases with P68640

2 regional properties for P68640

Type Name Position InterPro Accession
domain Hypersensitivity response secretion-like, HrpJ 60 - 223 IPR010812
domain Type III secretion regulator, YopN/LcrE/InvE/MxiC 36 - 280 IPR013401

Functions

Description
EC Number
Subcellular Localization
  • Cell outer membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell outer membrane A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
cell surface The external part of the cell wall and/or plasma membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
negative regulation of protein secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
protein secretion by the type III secretion system The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTLHNLSYG NTPLHNERPE IASSQIVNQT LGQFRGESVQ IVSGTLQSIA DMAEEVTFVF
70 80 90 100 110 120
SERKELSLDK RKLSDSQARV SDVEEQVNQY LSKVPELEQK QNVSELLSLL SNSPNISLSQ
130 140 150 160 170 180
LKAYLEGKSE EPSEQFKMLC GLRDALKGRP ELAHLSHLVE QALVSMAEEQ GETIVLGARI
190 200 210 220 230 240
TPEAYRESQS GVNPLQPLRD TYRDAVMGYQ GIYAIWSDLQ KRFPNGDIDS VILFLQKALS
250 260 270 280 290
ADLQSQQSGS GREKLGIVIS DLQKLKEFGS VSDQVKGFWQ FFSEGKTNGV RPF