P61018
PR
Gene name |
RAB4B (PP1596) |
Protein name |
Ras-related protein Rab-4B |
Names |
|
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:53916 |
EC number |
3.6.5.2: Acting on GTP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P61018
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2O52 | X-ray | 220 A | A/B | 6-183 | PDB |
| AF-P61018-F1 | Predicted | AlphaFoldDB |
175 variants for P61018
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs765626830 CA9451840 |
3 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405952945 rs1381792601 |
4 | T>I | No |
ClinGen TOPMed |
|
|
CA9451841 rs773595717 |
5 | Y>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 8 | L>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9451868 rs753430798 |
11 | F>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs761358392 CA9451869 |
14 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA9451870 rs764996394 |
16 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA405953056 rs1288599356 |
19 | T>S | No |
ClinGen gnomAD |
|
|
CA9451872 rs142878680 |
24 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1241087753 CA405953107 |
27 | Q>* | No |
ClinGen TOPMed |
|
|
CA405953123 rs1175527269 |
29 | I>T | No |
ClinGen gnomAD |
|
|
CA9451874 rs751491039 |
29 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1237701860 CA405953133 |
30 | E>D | No |
ClinGen gnomAD |
|
|
rs778955458 CA9451901 |
36 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953203 rs1309107291 |
38 | N>S | No |
ClinGen TOPMed |
|
|
rs1041291101 CA308470860 |
41 | I>V | No |
ClinGen TOPMed |
|
|
rs776207470 CA9451904 |
42 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA9451906 rs769467373 |
43 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA9451907 rs772810720 |
48 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA405953267 rs1247222554 |
48 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA405953272 rs1365003056 |
49 | V>L | No |
ClinGen TOPMed |
|
| TCGA novel | 50 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1422426846 CA405953278 |
50 | V>I | No |
ClinGen gnomAD |
|
|
rs78547965 CA308470908 |
51 | N>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs78547965 CA9451909 |
51 | N>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9451910 rs773805522 |
51 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9451912 rs777904747 CA405953287 |
52 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9451913 rs777904747 |
52 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953292 rs1486174906 |
53 | G>C | No |
ClinGen TOPMed |
|
|
rs150917359 CA9451914 |
54 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs150917359 CA308470952 |
54 | G>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1352140021 CA405953317 |
57 | V>L | No |
ClinGen gnomAD |
|
|
rs1341336243 CA405953331 |
59 | L>Q | No |
ClinGen gnomAD |
|
|
rs1325374746 CA405953330 |
59 | L>V | No |
ClinGen gnomAD |
|
|
CA308470984 rs1005964701 |
62 | W>* | No |
ClinGen Ensembl |
|
| rs766157650 | 62 | W>G | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9451917 rs753975240 |
63 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA405953369 rs1228978306 |
64 | T>M | No |
ClinGen gnomAD |
|
|
rs1361542648 CA405953380 |
66 | G>V | No |
ClinGen gnomAD |
|
|
CA9451919 rs779202480 |
69 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953404 rs1599738552 |
70 | F>V | No |
ClinGen Ensembl |
|
|
rs373783874 CA9451921 |
71 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9451920 rs746085545 |
71 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1480941114 CA405953426 |
72 | S>T | No |
ClinGen TOPMed gnomAD |
|
|
CA9451939 rs750712433 |
74 | T>M | No |
ClinGen ExAC gnomAD |
|
|
CA9451942 rs747390800 |
75 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA9451941 rs780375061 |
75 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs1446141913 CA405953460 |
77 | Y>* | No |
ClinGen gnomAD |
|
|
CA405953473 rs1377592404 |
79 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
| TCGA novel | 80 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405953483 rs1240875338 |
81 | A>S | No |
ClinGen gnomAD |
|
|
rs890530071 CA308473495 |
81 | A>V | No |
ClinGen gnomAD |
|
|
rs111403859 CA308473509 |
83 | G>E | No |
ClinGen Ensembl |
|
|
rs1200743247 CA405953492 |
83 | G>R | No |
ClinGen gnomAD |
|
|
CA9451945 rs139412370 |
84 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA405953511 rs1599741805 |
86 | L>R | No |
ClinGen Ensembl |
|
|
CA405953515 rs1599741812 |
87 | V>G | No |
ClinGen Ensembl |
|
|
rs1380641347 CA405953519 |
88 | Y>H | No |
ClinGen TOPMed gnomAD |
|
|
rs745346571 CA9451948 |
89 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1377482803 CA405953538 |
90 | I>S | No |
ClinGen gnomAD |
|
|
CA405953565 rs1304775229 |
92 | S>R | No |
ClinGen gnomAD |
|
|
CA9451967 rs145620655 |
93 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs771504169 CA9451966 |
93 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs746629770 CA9451968 |
96 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA308473624 rs950991451 |
98 | S>A | No |
ClinGen gnomAD |
|
|
CA405953609 rs1265328708 |
100 | A>P | No |
ClinGen gnomAD |
|
|
rs768546725 CA9451969 |
101 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA308473626 rs775977385 |
101 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA9451971 rs761618952 |
104 | T>M | No |
ClinGen ExAC gnomAD |
|
|
rs1599741998 CA405953641 |
105 | D>G | No |
ClinGen Ensembl |
|
|
CA405953639 rs1264141377 |
105 | D>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA405953650 rs1202172147 |
106 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA308473633 rs770414180 |
107 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA9451973 rs556443632 |
107 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9451975 rs766549736 |
108 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953655 rs763187442 |
108 | T>P | No |
ClinGen ExAC gnomAD |
|
|
rs763187442 CA9451974 |
108 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs1340937728 CA405953660 |
109 | L>V | No |
ClinGen TOPMed |
|
|
CA9451978 rs767742665 |
111 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753029143 CA9451979 |
112 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs144342132 CA9451981 |
115 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9451982 rs754339375 |
117 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9451983 rs757962432 |
118 | L>I | No |
ClinGen ExAC gnomAD |
|
|
rs1473804485 CA405953740 |
121 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1398785614 CA405953761 |
124 | D>G | No |
ClinGen TOPMed |
|
|
rs1599742041 CA405953757 |
124 | D>N | No |
ClinGen Ensembl |
|
|
rs1284508297 CA405953782 |
127 | P>R | No |
ClinGen gnomAD |
|
|
CA9451984 rs147795402 |
127 | P>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs754608109 CA9451986 |
129 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs754608109 CA9451987 |
129 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs148835785 CA9451985 |
129 | R>W | No |
ClinGen ESP ExAC gnomAD |
|
|
CA9451988 rs747898878 |
130 | E>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA405953797 rs1199920796 |
130 | E>V | No |
ClinGen TOPMed gnomAD |
|
|
CA405953816 rs1165085155 |
133 | F>S | No |
ClinGen TOPMed gnomAD |
|
|
CA9451991 rs376946189 |
135 | E>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs771172562 CA9451992 |
137 | S>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA308473759 rs915142309 |
137 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs201807135 CA9451993 |
138 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953844 rs1159610126 |
138 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs759614557 CA9451994 |
140 | A>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs759614557 CA9451995 |
140 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775719466 CA9451996 |
141 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA9451997 rs761095153 |
143 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA9451998 rs190786709 |
144 | E>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9452022 rs752435549 |
146 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs1439238621 CA405953911 |
146 | M>T | No |
ClinGen TOPMed |
|
|
rs1190438468 CA405953922 |
147 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1568493359 CA405953919 |
147 | F>S | No |
ClinGen Ensembl |
|
|
CA9452024 rs755859199 |
150 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA308477768 rs965412357 |
150 | T>S | No |
ClinGen TOPMed |
|
|
CA9452027 rs757049679 |
152 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953952 rs1175065668 |
152 | A>V | No |
ClinGen TOPMed |
|
|
CA9452028 rs778787860 |
153 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953959 rs1348673277 |
154 | T>A | No |
ClinGen gnomAD |
|
|
rs768877367 CA9452033 |
156 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747053848 CA9452032 |
156 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA9452034 rs776766859 |
157 | N>D | No |
ClinGen ExAC gnomAD |
|
|
rs770176888 CA9452037 |
158 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770176888 CA405953984 |
158 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405953990 rs1221431706 |
159 | E>* | No |
ClinGen TOPMed gnomAD |
|
|
CA9452039 rs773639945 |
160 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs1213191971 CA405954003 |
161 | A>T | No |
ClinGen TOPMed |
|
|
CA308477813 rs920021539 |
161 | A>V | No |
ClinGen TOPMed |
|
|
rs759985564 CA9452041 |
167 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759985564 CA308477823 |
167 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405954045 rs1241173630 |
167 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA405954058 rs1187799657 |
169 | I>T | No |
ClinGen gnomAD |
|
|
rs1475430259 CA405954055 |
169 | I>V | No |
ClinGen gnomAD |
|
|
rs752276208 CA9452042 |
170 | L>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 173 | I>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405954086 rs1418266498 |
173 | I>T | No |
ClinGen gnomAD |
|
|
rs1599744567 CA405954099 |
175 | S>A | No |
ClinGen Ensembl |
|
|
rs751481760 CA9452070 |
176 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA9452043 rs760207054 |
176 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA308477941 rs1053209025 |
177 | E>K | No |
ClinGen Ensembl |
|
|
rs781217440 CA9452072 |
180 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs748136181 CA9452073 |
180 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9452074 rs756379787 |
181 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 181 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA405954163 rs1419905679 |
183 | M>I | No |
ClinGen TOPMed |
|
|
rs1178730750 CA405954170 |
184 | G>A | No |
ClinGen gnomAD |
|
|
rs1178730750 CA405954169 |
184 | G>D | No |
ClinGen gnomAD |
|
|
rs777797873 CA9452075 |
186 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1444555381 CA405954181 |
186 | G>V | No |
ClinGen gnomAD |
|
|
rs775055908 CA9452078 |
188 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs372110075 CA9452077 |
188 | Q>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 189 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs768325395 CA9452080 |
190 | G>R | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA405954215 rs1316590092 |
191 | D>E | No |
ClinGen gnomAD |
|
|
rs140334186 CA9452082 |
191 | D>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs145079075 CA405954220 |
192 | A>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9452083 rs145079075 |
192 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9452085 rs772732312 |
193 | S>F | No |
ClinGen ExAC |
|
|
rs1599744809 CA405954222 |
193 | S>P | No |
ClinGen Ensembl |
|
|
rs201478253 CA9452086 |
195 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs766136140 CA9452087 |
195 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405954244 rs1599744831 |
197 | L>F | No |
ClinGen Ensembl |
|
|
rs369688842 CA9452088 |
198 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376333639 CA9452090 |
198 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369688842 CA9452089 |
198 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA9452092 rs200980353 |
201 | R>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs200980353 CA308477981 |
201 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9452091 rs752833331 |
201 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA405954275 rs1599744843 |
202 | S>R | No |
ClinGen Ensembl |
|
|
CA405954276 rs1167316790 |
203 | A>T | No |
ClinGen gnomAD |
|
|
CA405954283 rs1439328175 |
204 | Q>E | No |
ClinGen Ensembl |
|
|
rs757746004 CA308477988 |
206 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs757746004 CA9452096 |
206 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA308477992 rs944147392 |
207 | A>T | No |
ClinGen TOPMed |
|
|
rs1415673287 CA405954308 |
208 | P>R | No |
ClinGen TOPMed |
|
|
rs779394141 CA9452097 |
208 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA9452098 rs746199030 |
209 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1568493616 CA405954317 |
210 | P>A | No |
ClinGen Ensembl |
|
|
rs372611375 CA9452099 |
210 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1599744882 CA405954343 |
213 | C>W | No |
ClinGen Ensembl |
No associated diseases with P61018
1 regional properties for P61018
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 10 - 162 | IPR005225 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.5.2 | Acting on GTP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| insulin-responsive compartment | A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2. |
| perinuclear region of cytoplasm | Cytoplasm situated near, or occurring around, the nucleus. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| recycling endosome | An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane. |
| secretory granule membrane | The lipid bilayer surrounding a secretory granule. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein activity | A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP). |
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| glucose import | The directed movement of the hexose monosaccharide glucose into a cell or organelle. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| Rab protein signal transduction | The series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state. |
| regulation of endocytosis | Any process that modulates the frequency, rate or extent of endocytosis. |
| vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2TBH7 | RAB4A | Ras-related protein Rab-4A | Bos taurus (Bovine) | PR |
| P61017 | RAB4B | Ras-related protein Rab-4B | Canis lupus familiaris (Dog) (Canis familiaris) | PR |
| Q8WUD1 | RAB2B | Ras-related protein Rab-2B | Homo sapiens (Human) | PR |
| P61019 | RAB2A | Ras-related protein Rab-2A | Homo sapiens (Human) | PR |
| P20338 | RAB4A | Ras-related protein Rab-4A | Homo sapiens (Human) | PR |
| P62491 | RAB11A | Ras-related protein Rab-11A | Homo sapiens (Human) | PR |
| Q15907 | RAB11B | Ras-related protein Rab-11B | Homo sapiens (Human) | PR |
| Q91ZR1 | Rab4b | Ras-related protein Rab-4B | Mus musculus (Mouse) | PR |
| P05714 | Rab4a | Ras-related protein Rab-4A | Rattus norvegicus (Rat) | PR |
| P51146 | Rab4b | Ras-related protein Rab-4B | Rattus norvegicus (Rat) | PR |
| Q6PHI9 | rab4a | Ras-related protein Rab-4A | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| Q68EK7 | rab4b | Ras-related protein Rab-4B | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAETYDFLFK | FLVIGSAGTG | KSCLLHQFIE | NKFKQDSNHT | IGVEFGSRVV | NVGGKTVKLQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IWDTAGQERF | RSVTRSYYRG | AAGALLVYDI | TSRETYNSLA | AWLTDARTLA | SPNIVVILCG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NKKDLDPERE | VTFLEASRFA | QENELMFLET | SALTGENVEE | AFLKCARTIL | NKIDSGELDP |
| 190 | 200 | 210 | |||
| ERMGSGIQYG | DASLRQLRQP | RSAQAVAPQP | CGC |