P60037

PR
Gene name
yidC
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) (Vibrio succinogenes)
KEGG Pathway
wsu:WS1286
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

7-106 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P60037

Entry ID Method Resolution Chain Position Source
AF-P60037-F1 Predicted AlphaFoldDB

No variants for P60037

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P60037

No associated diseases with P60037

3 regional properties for P60037

Type Name Position InterPro Accession
domain Membrane insertase YidC, N-terminal 12 - 337 IPR028053
domain Membrane insertase YidC/Oxa/ALB, C-terminal 338 - 518 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 340 - 518 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLDNFDKLNL QMRILIATAI SLLFFIPYSY FFAPVKEAPL KESTSMERAE QQAAPQTSSS
70 80 90 100 110 120
PKEGQVSSVA MAETSPSKDI IATVQGSHFR LEIDSLGRIA QVYLKDAKFL KEQKELPLLA
130 140 150 160 170 180
PLSSLRPLEV RFSDATTNKE AFAKSYYSDR DLVEIRNTPE TLTLTQELEG FKLTKKLTFY
190 200 210 220 230 240
PDGNYDLEVE TSGSQKRFFL SPGARPIAES DKFAFNGVVL KESGGTIHTT EDGDAKKDEI
250 260 270 280 290 300
FEGARFVASV DRYYTTLFFV KEPQGLRVVI SKNAEKNPEP FVEALDHLKL SGYIGAKDFR
310 320 330 340 350 360
LLESIYPSLT DVVEYGFITF FAKPLFLLLD WLYKFCGNWG WAIVLLTLVV RIILFPLTYK
370 380 390 400 410 420
GMVSMQKLKD IAPKMKEIQE KYKGDPQKLQ VHMMELYKKH GANPMGGCLP LLLQMPIFFA
430 440 450 460 470 480
IYRVLYNAIE LKGADWILWI NDLSVMDPYF ILPILMGASM FLQQHLTPTT FTDPMQEKVF
490 500 510 520 530
KFLPLIFTFF FVTFPSGLVL YWFVSNVFSI AQQLFINKTL EAKKRAAAAK PSGLSD