| acetylcholine receptor signaling pathway |
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands. |
| activation of GTPase activity |
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP. |
| animal organ morphogenesis |
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. |
| anterior/posterior pattern specification |
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. |
| B cell apoptotic process |
Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. |
| blood vessel development |
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. |
| cell chemotaxis |
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). |
| cell migration |
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms. |
| cellular response to interleukin-7 |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus. |
| cellular response to transforming growth factor beta stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. |
| cellular response to xenobiotic stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. |
| cerebellar neuron development |
The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. |
| cerebral cortex development |
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. |
| cranial skeletal system development |
The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. |
| dendrite development |
The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. |
| endothelin receptor signaling pathway |
A G protein-coupled receptor signaling pathway initiated by endothelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| establishment of cell polarity |
The specification and formation of anisotropic intracellular organization or cell growth patterns. |
| fibroblast growth factor receptor signaling pathway |
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. |
| heart development |
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
| helper T cell diapedesis |
The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. |
| hippocampus development |
The progression of the hippocampus over time from its initial formation until its mature state. |
| lipid metabolic process |
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. |
| male gonad development |
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. |
| negative regulation of gene expression |
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| negative regulation of protein phosphorylation |
Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. |
| neuron migration |
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. |
| outflow tract morphogenesis |
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. |
| parathyroid gland development |
The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone. |
| pattern specification process |
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. |
| pharynx development |
The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. |
| positive regulation of cell population proliferation |
Any process that activates or increases the rate or extent of cell proliferation. |
| positive regulation of ERK1 and ERK2 cascade |
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. |
| positive regulation of glial cell migration |
Any process that activates or increases the frequency, rate or extent of glial cell migration. |
| positive regulation of MAPK cascade |
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. |
| positive regulation of protein phosphorylation |
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. |
| positive regulation of substrate adhesion-dependent cell spreading |
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading. |
| reelin-mediated signaling pathway |
The series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| regulation of cell adhesion mediated by integrin |
Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin. |
| regulation of cell growth |
Any process that modulates the frequency, rate, extent or direction of cell growth. |
| regulation of dendrite development |
Any process that modulates the frequency, rate or extent of dendrite development. |
| regulation of gene expression |
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| regulation of leukocyte migration |
Any process that modulates the frequency, rate, or extent of leukocyte migration. |
| regulation of skeletal muscle acetylcholine-gated channel clustering |
Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering. |
| regulation of T cell migration |
Any process that modulates the frequency, rate or extent of T cell migration. |
| response to fibroblast growth factor |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus. |
| retinoic acid receptor signaling pathway |
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands. |
| signal transduction |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
| single fertilization |
The union of male and female gametes to form a zygote. |
| spermatogenesis |
The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
| synapse assembly |
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). |
| T cell receptor signaling pathway |
The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. |
| thymus development |
The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components. |
| urogenital system development |
The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. |
