P47702

PR
Gene name
yidC (MG464)
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) (Mycoplasmoides genitalium)
KEGG Pathway
mge:MG_464
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

158-237 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P47702

Entry ID Method Resolution Chain Position Source
AF-P47702-F1 Predicted AlphaFoldDB

No variants for P47702

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P47702

No associated diseases with P47702

2 regional properties for P47702

Type Name Position InterPro Accession
domain Membrane insertase YidC/Oxa/ALB, C-terminal 149 - 360 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 168 - 361 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

2 GO annotations of biological process

Name Definition
protein insertion into membrane The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPIKLAQTNK EIKTTFNPFW SAAVVNEKNN WKNFKKFSAI FIKVIKVFIF IFLTIVGLWG
70 80 90 100 110 120
CTQTLAQPWT GTNQVLGSGL EIGYKFGTTG DYRYDLISNN FGPYFTFSDY TLAYGPFYGW
130 140 150 160 170 180
FVWPAAQIVL PIMYATRVPL GSGVELGFNM ILSLIVLLLL VRLITIVITL NSTLALEKMN
190 200 210 220 230 240
EVQGKLAEIN AKYKGAIDLQ SKRNRQLEIM SLYKKHNIKS SAAFVQVFVT LPIFLIIYRI
250 260 270 280 290 300
VTTLRPIKAI ILFNFWDLSK VPLTEIFSNF TTTGWPFIIF LVIVLPVQFL SQKLPQVWAS
310 320 330 340 350 360
KRNENAKAHS QKSIEQLNKT KKMQLIFYFV FAAITAFSAA GVGVYWFLNA LFTLLQSYLT
370 380
HVFIVKRREK RKQNYSKLDL ILERE