AiPD: Autoinhibited Protein Database

Gene name	HAT9 (At2g22800, T20K9.1, T30L20.6)
Protein name	Homeobox-leucine zipper protein HAT9
Names	Homeodomain-leucine zipper protein HAT9, HD-ZIP protein 9
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT2G22800
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

53-130 (Predicted disordered autoinhibitory region) PR

53-130 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-P46603-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH05559947	17	P>L	No	1000Genomes
tmp_2_9705988_G_A	21	P>S	No	1000Genomes
ENSVATH01869087	22	N>H	No	1000Genomes
ENSVATH14534321	27	T>I	No	1000Genomes
ENSVATH14534320	28	I>S	No	1000Genomes
ENSVATH05559946	33	V>A	No	1000Genomes
ENSVATH13336583	43	C>S	No	1000Genomes
ENSVATH13336582	54	T>I	No	1000Genomes
ENSVATH05559943	57	D>G	No	1000Genomes
ENSVATH00242795	62	Q>H	No	1000Genomes
tmp_2_9705861_G_A	63	T>M	No	1000Genomes
ENSVATH01869086	77	V>L	No	1000Genomes
tmp_2_9705807_T_G	81	E>A	No	1000Genomes
tmp_2_9705796_C_G	85	G>R	No	1000Genomes
tmp_2_9705765_G_A	95	T>M	No	1000Genomes
tmp_2_9705754_T_A	99	I>L	No	1000Genomes
ENSVATH13336580	120	Q>E	No	1000Genomes
tmp_2_9705671_C_A	126	E>D	No	1000Genomes
ENSVATH13336570	145	R>I	No	1000Genomes
ENSVATH13336569	146	Q>K	No	1000Genomes
ENSVATH05559941	148	N>S	No	1000Genomes
tmp_2_9705485_C_T	154	V>I	No	1000Genomes
ENSVATH14534318	172	V>I	No	1000Genomes
tmp_2_9705248_A_T	176	F>I	No	1000Genomes
ENSVATH13336549	185	A>T	No	1000Genomes
tmp_2_9705205_C_T	190	R>K	No	1000Genomes
tmp_2_9705173_G_T	201	L>I	No	1000Genomes
tmp_2_9705121_TTCGTTAGAG_ATCGTTAGAG,T	218	K>M	No	1000Genomes
tmp_2_9705115_G_C	220	P>R	No	1000Genomes
ENSVATH05559935	226	G>S	No	1000Genomes
ENSVATH05559934	229	G>D	No	1000Genomes
ENSVATH13336532	240	G>V	No	1000Genomes
ENSVATH13336531	243	A>P	No	1000Genomes
tmp_2_9705031_C_T	248	G>E	No	1000Genomes
tmp_2_9705028_C_T	249	S>N	No	1000Genomes
tmp_2_9705017_C_T	253	G>R	No	1000Genomes
tmp_2_9705005_T_C	257	I>V	No	1000Genomes
ENSVATH00242794	260	K>T	No	1000Genomes
tmp_2_9704988_G_T	262	H>Q	No	1000Genomes
tmp_2_9704968_T_C	269	N>S	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Homeobox domain	108 - 172	IPR001356
domain	Leucine zipper, homeobox-associated	168 - 211	IPR003106
conserved_site	Homeobox, conserved site	143 - 166	IPR017970

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
DNA-binding transcription factor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
sequence-specific DNA binding	Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

Name	Definition
No GO annotations for biological process

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q03014	HHEX	Hematopoietically-expressed homeobox protein HHEX	Homo sapiens (Human)	PR
P52952	NKX2-5	Homeobox protein Nkx-2.5	Homo sapiens (Human)	PR
P49639	HOXA1	Homeobox protein Hox-A1	Homo sapiens (Human)	SS
P35452	HOXD12	Homeobox protein Hox-D12	Homo sapiens (Human)	PR
Q99801	NKX3-1	Homeobox protein Nkx-3.1	Homo sapiens (Human)	PR
P42582	Nkx2-5	Homeobox protein Nkx-2.5	Mus musculus (Mouse)	PR
P70397	Dlx6	Homeobox protein DLX-6	Mus musculus (Mouse)	PR
P09022	Hoxa1	Homeobox protein Hox-A1	Mus musculus (Mouse)	SS
O08656	Hoxa1	Homeobox protein Hox-A1	Rattus norvegicus (Rat)	SS
A2D649	HOXB1	Homeobox protein Hox-B1	Macaca mulatta (Rhesus macaque)	SS
Q6H6S3	HOX24	Homeobox-leucine zipper protein HOX24	Oryza sativa subsp japonica (Rice)	PR
Q7XUJ5	HOX22	Homeobox-leucine zipper protein HOX22	Oryza sativa subsp japonica (Rice)	PR
Q5VPE5	HOX28	Homeobox-leucine zipper protein HOX28	Oryza sativa subsp japonica (Rice)	PR
A3BYC1	HOX25	Homeobox-leucine zipper protein HOX25	Oryza sativa subsp japonica (Rice)	PR
Q9FN29	ATHB-52	Homeobox-leucine zipper protein ATHB-52	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9M276	ATHB-12	Homeobox-leucine zipper protein ATHB-12	Arabidopsis thaliana (Mouse-ear cress)	PR
Q6F2E2	vex1	Homeobox protein vex1	Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)	PR
Q98875	dlx1a	Homeobox protein Dlx1a	Danio rerio (Zebrafish) (Brachydanio rerio)	PR
Q98878	dlx4b	Homeobox protein Dlx4b	Danio rerio (Zebrafish) (Brachydanio rerio)	PR