P45650

PR
Gene name
yidC
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
KEGG Pathway
cbu:CBU_1920
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-88 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P45650

Entry ID Method Resolution Chain Position Source
AF-P45650-F1 Predicted AlphaFoldDB

No variants for P45650

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P45650

No associated diseases with P45650

3 regional properties for P45650

Type Name Position InterPro Accession
domain Membrane insertase YidC, N-terminal 4 - 366 IPR028053
domain Membrane insertase YidC/Oxa/ALB, C-terminal 368 - 547 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 383 - 547 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

2 GO annotations of biological process

Name Definition
protein insertion into membrane The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIKRIILYV IVALLAIALF NAWQRDYPPT PKPTPTVEQP TANGDHPTAY TPPAFTPGAA
70 80 90 100 110 120
EKTKKAGTIA FTSKVPEARL ITVRTDVLDV EIDTQGGNIV SAKLPKYPVS LEEKQTPVQI
130 140 150 160 170 180
LSGEPNELYI AQSGLTNGNG QPTTVQFESE KKQYVLENGQ NQLIVQLTGR APDGLLVTKT
190 200 210 220 230 240
YTFHRDDYAI HLAYQVKNNT SKPWQGSLYT QITRRQPPTE HHHFYVRSYN GASMGSPQTP
250 260 270 280 290 300
YEKLSYESLD KQNIDRTSQS GWIAMQQHYF LSAWVPGNPE LTYHYYSHVI PASDEPNVYV
310 320 330 340 350 360
VGFVSPQMNV AAGSEAATHA TLYVGPEIAK RLKGLAPGLE RTIDYGWLWP ISMLLFWILS
370 380 390 400 410 420
AVHAVVKNWG WSIIITTILI KIVFYWFSAK SFRSMARMRE MQPRIQALKE RHGDDRQALS
430 440 450 460 470 480
RATMELYRKE KINPLGGCLP MLIQVPVFIA FYYVIIESVQ LRQAPFIFWI HDLSVKDPYY
490 500 510 520 530 540
ILPIIMGLSM LAQQWVSPTS PDPTQQKMMW ILPVIFTVFF INFPAGLVLY WITNNVVQTL
550 560
QQWYVNKTYE SHKAKLKARR ARKRKR