P34668
Gene name |
ZK686.2 |
Protein name |
Putative ATP-dependent RNA helicase ZK686.2 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_ZK686.2 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P34668
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P34668-F1 | Predicted | AlphaFoldDB |
No variants for P34668
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P34668 | |||||
No associated diseases with P34668
5 regional properties for P34668
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 469 - 477 | IPR000629 |
| domain | Helicase, C-terminal | 577 - 723 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 216 - 511 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 211 - 541 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 192 - 220 | IPR014014 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| P granule | A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
12 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P53166 | MRH4 | ATP-dependent RNA helicase MRH4, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| P15424 | MSS116 | ATP-dependent RNA helicase MSS116, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q29S22 | DDX47 | Probable ATP-dependent RNA helicase DDX47 | Bos taurus (Bovine) | PR |
| Q9H0S4 | DDX47 | Probable ATP-dependent RNA helicase DDX47 | Homo sapiens (Human) | PR |
| Q9CWX9 | Ddx47 | Probable ATP-dependent RNA helicase DDX47 | Mus musculus (Mouse) | PR |
| Q7Y183 | RH10 | DEAD-box ATP-dependent RNA helicase 10 | Oryza sativa subsp japonica (Rice) | PR |
| Q8L4E9 | Os07g0633500 | DEAD-box ATP-dependent RNA helicase 36 | Oryza sativa subsp japonica (Rice) | PR |
| P34580 | T26G10.1 | Putative ATP-dependent RNA helicase T26G10.1 | Caenorhabditis elegans | PR |
| P34640 | ZK512.2 | Probable ATP-dependent RNA helicase DDX55 homolog | Caenorhabditis elegans | PR |
| P27639 | inf-1 | Eukaryotic initiation factor 4A | Caenorhabditis elegans | PR |
| Q9SA27 | RH36 | DEAD-box ATP-dependent RNA helicase 36 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GY84 | RH10 | DEAD-box ATP-dependent RNA helicase 10 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKRKNQKEDS | DTENDDEIEP | ANGDGIEQEM | NRVTNGNEDD | ESVGNDVAEP | METEDVEDSG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EVEIEETAQN | GEREIFKVLG | KQEMKNLEAL | KVTSSWVQNA | TTFSATIDSS | TSQKLSQIEL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEHLTVPSAI | STWFPVQYAV | LPSLFFEIRS | PPPLRPRDVA | IAAPTGSGKT | ICYVLPVLAA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VGSKPSKILQ | AVILVPVQTL | VAQIVDEFKR | WNDESGVAKV | VSLSGANDFE | KEARQLASDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PNVIVATPAR | LVQHLTSKIP | PPIDLSKLRF | LIVDEADRMG | KLMREEWLDL | VEFLCGGMER |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VACLKDIIRQ | RRAPQKIVLS | ATLSKDVEEL | HLWNLFKPRL | FSATAVSVKD | ITSGIPQVDH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VSGRLALPSS | ISHRLVVTDP | KFHPLAVYQQ | ITRNKFNRTL | IFVNEVSSSN | RLAHVLKELC |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KDQFEVDYFT | AQLFGKRRYK | MLEKFNKNEN | RVLICSDVLA | RGTDLNKVDC | VINYNLPADD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KLFVHRAGRT | GRAGQDGYVI | SVGDKESKRL | FVKMLKVTNL | WGDTVEEQME | EYIFEKDMDR |
| 550 | 560 | 570 | 580 | 590 | |
| YSKALESLKA | TVSSQAKTGG | SRQIAKRSGF | EAKRKSRPNA | RGEKPWLKKK | TTE |