P34640
Gene name |
ZK512.2 |
Protein name |
Probable ATP-dependent RNA helicase DDX55 homolog |
Names |
DEAD box protein 55 |
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_ZK512.2 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P34640
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P34640-F1 | Predicted | AlphaFoldDB |
No variants for P34640
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P34640 | |||||
No associated diseases with P34640
5 regional properties for P34640
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 164 - 172 | IPR000629 |
| domain | Helicase, C-terminal | 231 - 393 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 33 - 201 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 28 - 235 | IPR014001 |
| domain | Domain of unknown function DUF4217 | 397 - 460 | IPR025313 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| P granule | A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2NL08 | DDX55 | ATP-dependent RNA helicase DDX55 | Bos taurus (Bovine) | PR |
| Q5ZLN8 | DDX55 | ATP-dependent RNA helicase DDX55 | Gallus gallus (Chicken) | PR |
| Q8NHQ9 | DDX55 | ATP-dependent RNA helicase DDX55 | Homo sapiens (Human) | PR |
| Q6ZPL9 | Ddx55 | ATP-dependent RNA helicase DDX55 | Mus musculus (Mouse) | PR |
| P34580 | T26G10.1 | Putative ATP-dependent RNA helicase T26G10.1 | Caenorhabditis elegans | PR |
| P34668 | ZK686.2 | Putative ATP-dependent RNA helicase ZK686.2 | Caenorhabditis elegans | PR |
| P27639 | inf-1 | Eukaryotic initiation factor 4A | Caenorhabditis elegans | PR |
| Q9FVV4 | RH55 | DEAD-box ATP-dependent RNA helicase 55 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8JHJ2 | ddx55 | ATP-dependent RNA helicase DDX55 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSKVGPVAL | KTFREKLGPE | LLEVFDKSYK | SFTDVQVLSG | THLLNLSDVV | VESPTGSGKT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LAFVLPMMRM | IQNAKLQPAD | IGALILSPSR | ELCSQIVSVI | QPFAEKLNLT | VETVTGGQKV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DKNIKMFKNK | NVNILVATPG | RLFQIIQHEK | TLIARKMRTL | QLLVIDEADR | FNEIQFEDHM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| REILSCIPKQ | RRTGLFSATQ | VKEEDDLMVF | GLRNAKQVKV | AQERNSAAPS | TLKNYYVECR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ADEKTSVCLE | FIRQRTDKKI | LIFFPSCNSV | RYFYKIFERC | LGKRPLFAVH | GKCSNPHRAS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QIKAFSDSTN | GVMISTDVMA | RGIDISDIDW | VIQFDLPKHS | SWFVHRAGRT | ARCGREGNAL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ILIASEQLAY | VNFLDNHEKV | KLDEIKVPTN | NSRKSEELRQ | KMIKIQVSDR | AILEAGTRAF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VSHVESYAKH | DCHLICSLDD | LNVVGLANSY | ALLRLPKMRE | LSQRKDLDMF | DRSAIETSEI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KYADVKLEAN | RETVMKEKHE | KKVETLAAKD | KKRREKEARK | LKKMGGRFRN | GGGTGRKAEE |
| 550 | 560 | 570 | |||
| KKALKRKAEE | EDDAQNDIRL | LKRIKRGKLS | KKEIKDVL |