Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P34454

Entry ID Method Resolution Chain Position Source
AF-P34454-F1 Predicted AlphaFoldDB

No variants for P34454

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P34454

No associated diseases with P34454

4 regional properties for P34454

Type Name Position InterPro Accession
domain SANT/Myb domain 278 - 330 IPR001005-1
domain SANT/Myb domain 349 - 405 IPR001005-2
domain DnaJ domain 34 - 99 IPR001623
domain SANT domain 352 - 407 IPR017884

Functions

Description
EC Number
Subcellular Localization
  • Nucleus membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q99543 DNAJC2 DnaJ homolog subfamily C member 2 Homo sapiens (Human) PR
P54103 Dnajc2 DnaJ homolog subfamily C member 2 Mus musculus (Mouse) PR
Q7TQ20 Dnajc2 DnaJ homolog subfamily C member 2 Rattus norvegicus (Rat) PR
F4KGY6 RVE1 Protein REVEILLE 1 Arabidopsis thaliana (Mouse-ear cress) PR
F4K5X6 RVE2 Protein REVEILLE 2 Arabidopsis thaliana (Mouse-ear cress) PR
Q6NWJ4 dnajc2 DnaJ homolog subfamily C member 2 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MRVILLLAFL ISLTECQWTS EDLALYDLVE EVGVNFYEWF DIPRDASSNQ VKKAYRKLTL
70 80 90 100 110 120
EWHPDRNSAP DATEKFRQVA GIYEVLKTTE LREKYDNVLE NGLPSWRHPM YYYRRMRKLA
130 140 150 160 170 180
WYEGILVLLF IGTIAHYLMM WAAYFEKTLV YKQNVKKSRK SKKEDPAEAE KLMKQALEEY
190 200 210 220 230 240
LPKYSELLPI ILARGTVTLF KNLALTAKDA MTPKEVEPEE PTEEELAQQR RQQRAAAAPQ
250 260 270 280 290 300
QLEFKFEVAQ GMKAVSTNDP EMEKKYAAEN EVVAQKQSGA TWTPDELASL VRLSTEKYPA
310 320 330 340 350 360
GTPNRWEQMG RVLNRSAEDV IAMAGKMKQM KQEDYTKLLM TTIQQSVPVE EKSEDDWSQA
370 380 390 400 410
EQKAFETALQ KYPKGTDERW ERISEEIGSK TKKQVMVRFK QLAEMIRKKK TNDT