P34318
Gene name |
set-3 (C07A9.7) |
Protein name |
SET domain-containing protein 3 |
Names |
|
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_C07A9.7 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P34318
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P34318-F1 | Predicted | AlphaFoldDB |
No variants for P34318
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P34318 | |||||
No associated diseases with P34318
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| histone deacetylase binding | Binding to histone deacetylase. |
| methyltransferase activity | Catalysis of the transfer of a methyl group to an acceptor molecule. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| methylation | The process in which a methyl group is covalently attached to a molecule. |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q0P585 | SMYD2 | N-lysine methyltransferase SMYD2 | Bos taurus (Bovine) | SS |
| E1C5V0 | SMYD2 | N-lysine methyltransferase SMYD2 | Gallus gallus (Chicken) | SS |
| Q5ZIZ2 | SMYD5 | Histone-lysine N-trimethyltransferase SMYD5 | Gallus gallus (Chicken) | PR |
| Q9NRG4 | SMYD2 | N-lysine methyltransferase SMYD2 | Homo sapiens (Human) | SS |
| Q6GMV2 | SMYD5 | Histone-lysine N-trimethyltransferase SMYD5 | Homo sapiens (Human) | PR |
| Q9H7B4 | SMYD3 | Histone-lysine N-methyltransferase SMYD3 | Homo sapiens (Human) | EV |
| Q8R5A0 | Smyd2 | N-lysine methyltransferase SMYD2 | Mus musculus (Mouse) | EV |
| Q3TYX3 | Smyd5 | Histone-lysine N-trimethyltransferase SMYD5 | Mus musculus (Mouse) | PR |
| Q9CWR2 | Smyd3 | Histone-lysine N-methyltransferase SMYD3 | Mus musculus (Mouse) | SS |
| C3RZA1 | SMYD2 | N-lysine methyltransferase SMYD2 | Sus scrofa (Pig) | SS |
| Q7M6Z3 | Smyd2 | N-lysine methyltransferase SMYD2 | Rattus norvegicus (Rat) | SS |
| Q5RGL7 | smyd2b | N-lysine methyltransferase SMYD2-B | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| Q5BJI7 | smyd2a | N-lysine methyltransferase SMYD2-A | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVEVPSFRSN | EHFPQLCDKV | TVKWDKKRGR | FVEAIEDIPI | GTVVCVETGI | TVNVDPQNCY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RCLKITENAS | FAYCKNCEEF | YEPDEIACGE | FDELGIFKLA | AHLVFSYPFA | DIASLVQSSD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEPPSCAPKA | LSTQDIEAIF | QLTPFPEIGE | AFKAPAIQNA | IKRIVESLET | DENWGRLDQI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SRTMTFTKAL | RIMAERSAKN | AHTIYSIEQI | ESQEDNLPMA | TGLFPISSIF | NHSCTPNISG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FFVRNTFIFV | SQGVRAREEL | LDSYGVTYHQ | HTFEQRTNFL | ASVSGFICHC | ESCFKMKSLK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLEKPKKYPE | TIATNASCFT | DITSYTENIP | RGSKELENLI | IAFARRPDSE | TYTELIFQFW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KKFVENAKFR | GITYDPYLVR | PYVEMTILAW | NKEVGCENEE | KMSLLIVTHR | LLRNCYVDLH |
| 430 | 440 | 450 | 460 | ||
| PLSELVVKLV | NVVANQNADE | INRTLEKLKL | RARMLWKYSE | QSEDL |