AiPD: Autoinhibited Protein Database

P32519

Gene name	ELF1
Protein name	ETS-related transcription factor Elf-1
Names	E74-like factor 1
Species	Homo sapiens (Human)
KEGG Pathway	hsa:1997
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

73-232 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

73-232 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

2 structures for P32519

Entry ID	Method	Resolution	Chain	Position	Source
8BZM	X-ray	269 A	B/H	206-294	PDB
AF-P32519-F1	Predicted				AlphaFoldDB

457 variants for P32519

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs200429572 CA6960439	3	A>G		No	ClinGen ExAC gnomAD
rs374182057 CA248391896	4	V>A		No	ClinGen ESP TOPMed
rs748231439 CA6960438	4	V>L		No	ClinGen ExAC
rs756035191 CA6960436	5	V>A		No	ClinGen ExAC gnomAD
CA6960434 rs767257215	6	Q>E		No	ClinGen ExAC gnomAD
rs757063129 CA6960433	6	Q>P		No	ClinGen ExAC
rs763768134 CA6960431	9	D>N		No	ClinGen ExAC gnomAD
CA248391859 rs188926643	11	V>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen 1000Genomes NCI-TCGA
CA6960430 rs186580740	12	F>Y		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA387923383 rs1456096696	13	E>A		No	ClinGen TOPMed gnomAD
TCGA novel	13	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6960429 rs752238485	14	F>L		No	ClinGen ExAC gnomAD
rs760051911 CA6960427	18	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA387923322 rs1323760946	19	M>T		No	ClinGen TOPMed
rs1442289656 CA387923294	21	D>G		No	ClinGen gnomAD
CA248391842 rs1041620375	21	D>H		No	ClinGen TOPMed
CA248391844 rs1041620375	21	D>N		No	ClinGen TOPMed
CA387923271 rs1205927640	23	R>*		No	ClinGen gnomAD
rs1327553855 CA387923267	23	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6960414 rs757178730	25	L>F		No	ClinGen ExAC gnomAD
rs1247860558 CA387921358	27	D>G		No	ClinGen TOPMed gnomAD
CA6960413 rs751363895	27	D>H		No	ClinGen ExAC gnomAD
CA6960410 rs752295265	28	P>Q		No	ClinGen ExAC gnomAD
rs144442221 CA6960412	28	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs144442221 CA6960411	28	P>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs759140767 CA6960408	29	A>S		No	ClinGen ExAC gnomAD
CA6960407 rs753447275	30	I>F		No	ClinGen ExAC TOPMed gnomAD
CA387921345 rs753447275	30	I>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	32	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA387921298 rs1250224504	37	E>G		No	ClinGen TOPMed
rs1202088721 CA387921270	41	G>D		No	ClinGen TOPMed
CA6960403 rs772338917	42	A>T		No	ClinGen ExAC gnomAD
rs762031797 CA6960402	43	D>G		No	ClinGen ExAC gnomAD
rs1255389775 CA387921241	46	N>D		No	ClinGen TOPMed
rs534615740 CA6960401	46	N>S		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA387921234 rs1194037303	47	S>G		No	ClinGen TOPMed
CA6960397 rs201253239	50	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs746934133 CA6960396	52	A>T		No	ClinGen ExAC gnomAD
TCGA novel	55	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs149627137 CA6960394	56	E>D		No	ClinGen 1000Genomes ExAC gnomAD
rs1245183016 CA387921168	57	P>A		No	ClinGen gnomAD
VAR_048942 CA6960393 rs7799	58	N>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1226290678 CA387921152	59	D>G		No	ClinGen TOPMed gnomAD
rs528981271 CA6960391	60	M>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs1341288815 CA387921147	60	M>V		No	ClinGen TOPMed gnomAD
CA6960390 rs35517822	61	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA387921124 rs1365288494	63	E>A		No	ClinGen gnomAD
TCGA novel	63	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs368030828 CA248382456	67	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ESP NCI-TCGA
CA387921092 rs1292579048	68	V>I		No	ClinGen gnomAD
rs1212179560 CA387921083	69	A>V		No	ClinGen gnomAD
rs1405241615 CA387921068	71	E>D		No	ClinGen TOPMed gnomAD
rs1342806677 CA387921063	72	E>G		No	ClinGen TOPMed
TCGA novel	72	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1367068371 CA387921058	73	I>V		No	ClinGen gnomAD
rs756590327 CA6960388	74	I>R		No	ClinGen ExAC TOPMed gnomAD
rs756590327 CA6960389	74	I>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	76	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA387921009 rs1309871245	79	D>V		No	ClinGen gnomAD
CA6960384 rs774733361	81	I>V		No	ClinGen ExAC gnomAD
CA387920988 rs1299994946	82	T>I		No	ClinGen TOPMed gnomAD
rs764292748 CA6960383	83	L>F		No	ClinGen ExAC TOPMed gnomAD
CA6960382 rs763216206	84	T>I		No	ClinGen ExAC gnomAD
rs949260327 CA248382433	85	V>I		No	ClinGen TOPMed gnomAD
rs949260327 CA387920975	85	V>L		No	ClinGen TOPMed gnomAD
CA387920947 rs1357435872	87	A>D		No	ClinGen gnomAD
rs1308439306 CA387920942	88	S>F		No	ClinGen TOPMed gnomAD
rs1308439306 CA387920940	88	S>Y		No	ClinGen TOPMed gnomAD
rs1393792610 CA387920936	89	C>Y		No	ClinGen gnomAD
rs1377566722 CA387920931	90	H>N		No	ClinGen gnomAD
CA6960358 rs748155244	92	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs960503567 CA248378726	95	T>I		No	ClinGen TOPMed
rs1453252651 CA387920884	96	I>M		No	ClinGen gnomAD
rs143714910 CA6960357	96	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA6960356 rs768578401	97	E>Q		No	ClinGen ExAC gnomAD
rs779598668 CA6960354	99	I>V		No	ClinGen ExAC gnomAD
CA387920846 rs1593356484	102	A>G		No	ClinGen Ensembl
CA387920836 rs1246032154	104	A>T		No	ClinGen gnomAD
CA387920812 rs1262153028	107	N>K		No	ClinGen gnomAD
rs1350852775 CA387920814	107	N>S		No	ClinGen gnomAD
TCGA novel	111	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs780809677 CA6960351	112	G>V		No	ClinGen ExAC gnomAD
CA6960350 rs371592585	113	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs955749417 CA248378614	114	M>T		No	ClinGen gnomAD
rs752065082 CA6960349	114	M>V		No	ClinGen ExAC gnomAD
CA6960348 rs778071991	116	D>G		No	ClinGen ExAC TOPMed gnomAD
rs560156235 CA248378611	119	R>*		No	ClinGen gnomAD
CA6960347 rs373684517	119	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1221470578	120	I>=	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753156108 CA6960346	120	I>L		No	ClinGen ExAC TOPMed gnomAD
CA387920730 rs1368387341	120	I>R		No	ClinGen TOPMed
CA248378594 rs753156108	120	I>V		No	ClinGen ExAC TOPMed gnomAD
rs770457576 CA6960332	123	N>S		No	ClinGen ExAC gnomAD
CA387920690 rs747465409	124	I>K		No	ClinGen ExAC TOPMed gnomAD
rs778229741 CA6960330	124	I>M		No	ClinGen ExAC gnomAD
rs747465409 CA6960331	124	I>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1224008681 CA387920692	124	I>V		No	ClinGen gnomAD
CA6960328 rs753000405	133	V>L		No	ClinGen ExAC TOPMed gnomAD
CA387920607 rs1231542518	136	P>Q		No	ClinGen gnomAD
rs1284194102 CA387920577	141	S>P		No	ClinGen gnomAD
CA6960325 rs149535884	142	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA387920562 rs1328097073	143	T>I		No	ClinGen gnomAD
rs1410522553 CA387920550	145	D>G		No	ClinGen gnomAD
rs1398563263 CA387920536	147	I>S		No	ClinGen gnomAD
CA387920527 rs1285868905	148	P>L		No	ClinGen TOPMed
CA387920530 rs1170554406	148	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6960324 rs766529280	151	M>V		No	ClinGen ExAC TOPMed gnomAD
CA387920490 rs1372512682	154	Q>K		No	ClinGen gnomAD
rs750583460 CA6960322	155	Q>R		No	ClinGen ExAC gnomAD
CA6960321 rs764119343	156	V>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	158	E>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6960318 rs769633777	161	A>S		No	ClinGen ExAC TOPMed gnomAD
rs776366937 CA387920430	162	D>G		No	ClinGen ExAC TOPMed gnomAD
rs759070371 CA6960317	162	D>N		No	ClinGen ExAC gnomAD
rs776366937 CA6960316	162	D>V		No	ClinGen ExAC TOPMed gnomAD
rs138109960 CA6960315	164	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA387920419 rs1323341015	164	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6960313 rs777331703	165	G>E		No	ClinGen ExAC gnomAD
rs1038873613 CA248377815	166	A>D		No	ClinGen TOPMed
rs772555990 CA6960312	166	A>P		No	ClinGen ExAC TOPMed gnomAD
rs748703479 CA6960311	167	S>L		No	ClinGen ExAC gnomAD
CA387920381 rs1406627366	171	Q>E		No	ClinGen gnomAD
rs1178123485 CA387920374	172	P>T		No	ClinGen gnomAD
TCGA novel	173	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6960307 rs780405638	174	R>K		No	ClinGen ExAC gnomAD
CA387920355 rs1235082709	174	R>S		No	ClinGen gnomAD
CA387920358 rs780405638	174	R>T		No	ClinGen ExAC gnomAD
CA6960306 rs756467275	175	K>R		No	ClinGen ExAC gnomAD
CA6960305 CA387920341 rs750513856	176	K>N		No	ClinGen ExAC gnomAD
TCGA novel	177	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA387920322 rs1448795739	178	R>G		No	ClinGen gnomAD
rs780618584 CA6960290	180	T>P		No	ClinGen ExAC gnomAD
CA387920296 rs1593351602	181	K>N		No	ClinGen Ensembl
CA387920280 rs1360010444	184	R>Q		No	ClinGen gnomAD
TCGA novel	186	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6960287 rs79890060	187	S>P		No	ClinGen ExAC gnomAD
rs757378602 CA6960286	188	P>A		No	ClinGen ExAC gnomAD
rs112601115 CA248374563	189	A>V		No	ClinGen Ensembl
CA6960284 rs765189689	191	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs765189689 CA6960285	191	T>R		No	ClinGen ExAC TOPMed gnomAD
rs1347773101 CA387920236	192	P>T		No	ClinGen gnomAD
rs766175737 CA6960281	194	I>M		No	ClinGen ExAC gnomAD
CA6960282 rs753617891	194	I>V		No	ClinGen ExAC TOPMed gnomAD
CA248374555 rs370152165	199	K>R		No	ClinGen ESP
CA387920184 rs1419320696	200	N>H		No	ClinGen gnomAD
rs772885144 CA6960279	200	N>K		No	ClinGen ExAC gnomAD
rs3764056 CA387920163	202	D>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
TCGA novel	203	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1391024830 CA387920161	203	G>R		No	ClinGen gnomAD
CA387920146 rs1221775431	205	G>R		No	ClinGen gnomAD
CA387920114 rs750270245	208	I>F		No	ClinGen ExAC TOPMed gnomAD
rs750270245 CA6960259	208	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1233417858 CA387920079	212	E>D		No	ClinGen gnomAD
rs1321203417 CA387920052	216	A>V		No	ClinGen gnomAD
rs751019407 CA6960256	218	L>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
TCGA novel CA387920026 rs1409127921	220	D>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA ClinGen TOPMed gnomAD
rs763510370 CA6960254	222	A>T		No	ClinGen ExAC gnomAD
CA387920004 rs1390343566	224	C>G		No	ClinGen gnomAD
CA6960252 rs770471341	232	Q>L		No	ClinGen ExAC gnomAD
CA387919938 rs1404452405	233	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs759947410 CA6960251	233	R>Q		No	ClinGen ExAC gnomAD
rs1180902156 CA387919921	235	K>N		No	ClinGen TOPMed gnomAD
CA387919878 rs1470394202	241	V>G		No	ClinGen gnomAD
CA6960250 rs372184198	245	A>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs932685150 CA248374154	248	R>G		No	ClinGen Ensembl
rs1593350979 CA387919821	250	W>*		No	ClinGen Ensembl
CA6960249 rs771170315	252	K>E		No	ClinGen ExAC gnomAD
CA248374143 rs921230105	252	K>R		No	ClinGen gnomAD
CA6960248 rs747210277	253	H>Y		No	ClinGen ExAC TOPMed gnomAD
rs866478181 CA248374138	254	K>E		No	ClinGen Ensembl
TCGA novel	255	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	259	M>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1232696114 CA387919755	259	M>R		No	ClinGen TOPMed
CA387919736 rs976836424	261	Y>*		No	ClinGen gnomAD
CA387919636 rs1342678791	274	R>G		No	ClinGen gnomAD
CA248372979 rs776730565	275	G>S		No	ClinGen Ensembl
rs1331781068 CA387919623	276	I>V		No	ClinGen gnomAD
CA6960225 rs745794216	278	A>T		No	ClinGen ExAC gnomAD
CA6960224 rs137863135	283	Q>E		No	ClinGen ESP ExAC gnomAD
CA387919571 rs1300069318	284	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA6960223 rs757021667	285	L>M		No	ClinGen ExAC gnomAD
CA387919543 rs1164173230	288	Q>R		No	ClinGen gnomAD
TCGA novel	293	P>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6960221 rs777535025	294	K>E		No	ClinGen ExAC TOPMed gnomAD
CA6960220 rs143469326	296	L>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1032880556 CA248372893	297	I>M		No	ClinGen TOPMed gnomAD
rs1196588785 CA387919477	297	I>T		No	ClinGen gnomAD
rs1281836151 CA387919464	299	I>K		No	ClinGen TOPMed
CA6960219 rs202087877	299	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs760268434	300	N>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	302	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1249909233 CA387919430	303	D>E		No	ClinGen TOPMed gnomAD
rs1359090159 CA387919433	303	D>G		No	ClinGen gnomAD
CA6960217 rs373079831	305	S>G		No	ClinGen ESP ExAC TOPMed gnomAD
CA6960215 rs754334265	308	I>M		No	ClinGen ExAC gnomAD
rs755476257 CA6960216	308	I>T		No	ClinGen ExAC gnomAD
rs532698900 CA6960213	309	E>K		No	ClinGen 1000Genomes ExAC gnomAD
rs532698900 CA6960214	309	E>Q		No	ClinGen 1000Genomes ExAC gnomAD
CA387919379 rs1247475675	311	S>L		No	ClinGen TOPMed
rs773668917 CA6960212	313	P>A		No	ClinGen ExAC gnomAD
CA6960211 rs767725443	313	P>R		No	ClinGen ExAC gnomAD
CA6960209 rs774343467	314	S>L		No	ClinGen ExAC gnomAD
rs1160683744 CA387919352	316	S>C		No	ClinGen TOPMed
rs770939173 CA6960205	319	A>P		No	ClinGen ExAC TOPMed gnomAD
CA387919332 rs1566165422	320	T>A		No	ClinGen Ensembl
CA6960204 rs370523749	320	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA248372824 rs76461227	321	S>*		No	ClinGen Ensembl
CA6960203 rs777768092	322	N>Y		No	ClinGen ExAC gnomAD
rs1200374067 CA387919315	323	R>G		No	ClinGen gnomAD
rs144532940 CA6960201	323	R>T		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	324	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs754470942 CA6960199	324	N>K		No	ClinGen ExAC
CA6960200 rs778527444	324	N>S		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	325	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	325	Q>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1340545303 CA387919292	326	T>I		No	ClinGen TOPMed gnomAD
rs753438585 CA6960198	326	T>P		No	ClinGen ExAC gnomAD
CA6960196 rs140646954	328	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA6960197 rs766771438	328	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6960195 rs750744628	329	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA6960193 rs146850967	330	R>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA387919257 rs990847340	331	V>I		No	ClinGen gnomAD
CA387919255 CA248372754 rs990847340	331	V>L		No	ClinGen gnomAD
CA609927622 rs1328157578	334	S>*		No	ClinGen gnomAD
CA387919177 rs1402278543	336	G>E		No	ClinGen gnomAD
rs774590357 CA6960192	337	V>E		No	ClinGen ExAC gnomAD
rs373106372 CA6960191	338	K>R		No	ClinGen ESP ExAC gnomAD
TCGA novel	339	G>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	340	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1468196137 CA387919113	340	G>R		No	ClinGen gnomAD
CA6960188 rs770770944	340	G>V		No	ClinGen ExAC gnomAD
CA248372677 rs909031062	342	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1056820 CA6960187	343	T>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
VAR_048943 rs1056820 CA6960186	343	T>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs571253522 CA248372666	347	P>L		No	ClinGen TOPMed gnomAD
CA387918994 rs1220352356	348	G>E		No	ClinGen TOPMed
rs12876270 CA248372665	349	N>K		No	ClinGen Ensembl
CA387918975 rs1461010809	349	N>S		No	ClinGen gnomAD
CA6960184 rs35449414	350	S>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA248372664 rs12876618	350	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
CA387918931 rs1184654884	352	A>P		No	ClinGen TOPMed
CA6960183 rs368881361	353	A>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA387918882 rs1566165326	355	P>R		No	ClinGen Ensembl
CA6960182 rs768401525	356	K>E		No	ClinGen ExAC TOPMed gnomAD
rs868591014 CA248372649	358	P>S		No	ClinGen gnomAD
CA387918847 rs868591014	358	P>T		No	ClinGen gnomAD
CA6960181 rs182666808	361	V>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA248372618 rs956883787	365	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA6960176 rs757590259	367	V>A		No	ClinGen ExAC gnomAD
CA387918717 rs1335820055	367	V>I		No	ClinGen gnomAD
CA387918706 rs1162402509	368	L>V		No	ClinGen TOPMed
rs751972706 CA6960175	369	R>T		No	ClinGen ExAC TOPMed gnomAD
CA6960174 rs764212056	371	V>M		No	ClinGen ExAC gnomAD
rs752654787 CA6960172	374	T>A		No	ClinGen ExAC gnomAD
CA6960170 rs751945909	375	Q>L		No	ClinGen ExAC gnomAD
CA6960169 rs576565224	376	S>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA387918639 rs1345732710	376	S>P		No	ClinGen gnomAD
CA387918635 rs1231336956	377	P>A		No	ClinGen gnomAD
rs376733820 CA6960167	379	P>L		No	ClinGen ESP ExAC gnomAD
CA387918590 rs1593349475	380	T>P		No	ClinGen Ensembl
CA387918566 rs1217475917	381	Q>H		No	ClinGen gnomAD
CA6960164 rs147423556	384	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs148475737 CA6960165	384	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA248372481 rs997506425	386	V>L		No	ClinGen TOPMed
rs779369118 CA6960163	387	H>D		No	ClinGen ExAC TOPMed gnomAD
CA248372464 rs865878592	387	H>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs142908880 CA6960162	388	V>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA248372422 rs900398539	393	Q>*		No	ClinGen gnomAD
CA6960159 rs757821336	393	Q>H		No	ClinGen ExAC TOPMed gnomAD
CA6960158 rs751919508	394	A>P		No	ClinGen ExAC gnomAD
CA248372409 rs866820215	395	V>D		No	ClinGen Ensembl
rs765191272 CA6960154	398	G>R		No	ClinGen ExAC gnomAD
rs945143204 CA248372390	399	E>G		No	ClinGen Ensembl
rs34905611 CA6960153	399	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
VAR_048944 CA6960151 rs7323148	403	T>I		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1194450704 CA387918226	404	S>N		No	ClinGen gnomAD
rs774219283 CA6960148	405	T>N		No	ClinGen ExAC TOPMed gnomAD
rs1221729054 CA387918202	406	M>V		No	ClinGen TOPMed gnomAD
CA387918173 rs1322269026	407	Q>H		No	ClinGen gnomAD
CA6960147 rs569468307	408	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs569468307 CA6960146	408	D>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs775181275 CA387918142	409	E>D		No	ClinGen ExAC gnomAD
rs1395683830 CA387918152	409	E>K		No	ClinGen TOPMed
CA6960144 rs769384979	411	L>F		No	ClinGen ExAC gnomAD
TCGA novel	413	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs776192222 CA6960142	415	V>A		No	ClinGen ExAC
rs114375975 CA6960143	415	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA6960139 rs201784200 CA387918041	416	Q>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA6960141 rs141136513	416	Q>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA248372281 rs1045885325	417	S>I		No	ClinGen TOPMed gnomAD
rs1327188116 CA387918013	418	I>T		No	ClinGen TOPMed
rs758821415 CA6960138	418	I>V		No	ClinGen ExAC gnomAD
rs1268456193 CA387918002	419	R>G		No	ClinGen TOPMed
CA387922877 rs1467314988	420	T>I		No	ClinGen TOPMed gnomAD
TCGA novel	420	T>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA6960121 rs772503411	421	I>L		No	ClinGen ExAC TOPMed gnomAD
CA6960120 rs772503411	421	I>V		No	ClinGen ExAC TOPMed gnomAD
rs1284345794 CA387922859	423	A>S		No	ClinGen TOPMed
rs1175744595 CA387922858	423	A>V		No	ClinGen gnomAD
rs1566162674 CA387922853	424	P>S		No	ClinGen Ensembl
CA6960119 rs748531706	425	T>P		No	ClinGen ExAC gnomAD
rs1427147318 CA387922843	426	Q>E		No	ClinGen gnomAD
CA6960118 rs779209874	427	V>I		No	ClinGen ExAC gnomAD
CA387922829 rs1480180125	428	P>S		No	ClinGen gnomAD
CA387922824 rs1238503234	429	V>L		No	ClinGen gnomAD
CA6960116 rs749531568	431	V>L		No	ClinGen ExAC TOPMed gnomAD
rs749531568 CA387922813	431	V>M		No	ClinGen ExAC TOPMed gnomAD
CA6960115 rs368042351	432	S>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA6960113 rs750520786	433	P>L		No	ClinGen ExAC TOPMed gnomAD
CA6960114 rs756235921	433	P>S		No	ClinGen ExAC TOPMed gnomAD
rs764082039 CA6960112	437	Q>R		No	ClinGen ExAC TOPMed gnomAD
rs375140290 CA6960111	440	T>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA6960110 rs752471658	442	T>S		No	ClinGen ExAC TOPMed gnomAD
CA6960109 rs765031385	445	T>A		No	ClinGen ExAC gnomAD
TCGA novel	449	T>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765000740 CA248396858	449	T>P		No	ClinGen TOPMed gnomAD
rs540284464 CA6960107	452	I>T		No	ClinGen ExAC TOPMed gnomAD
CA6960108 rs199564946	452	I>V		No	ClinGen 1000Genomes ExAC gnomAD
CA6960106 rs766060383	453	A>V		No	ClinGen ExAC gnomAD
rs760208850 CA6960105	454	S>C		No	ClinGen ExAC gnomAD
rs1001223538 CA387922632	455	T>I		No	ClinGen TOPMed
rs1001223538 CA248396841	455	T>K		No	ClinGen TOPMed
rs371815642 CA6960104	456	D>A		No	ClinGen ESP ExAC TOPMed gnomAD
CA6960103 rs41306656	458	S>P		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA387922606 rs1484034674	460	G>R		No	ClinGen gnomAD
rs1376936113 CA387922602	460	G>V		No	ClinGen Ensembl
rs1023178685 CA248396825	463	S>F		No	ClinGen Ensembl
CA6960101 rs145860913	463	S>T		No	ClinGen ESP ExAC TOPMed gnomAD
rs749478443 CA6960099	465	K>N		No	ClinGen ExAC TOPMed gnomAD
CA6960100 rs769160866	465	K>T		No	ClinGen ExAC TOPMed gnomAD
rs1365897814 CA387922564	466	F>L		No	ClinGen TOPMed
rs780405648 CA6960098	467	I>F		No	ClinGen ExAC TOPMed
CA387922563 rs780405648	467	I>L		No	ClinGen ExAC TOPMed
CA6960096 rs745958024	468	L>*		No	ClinGen ExAC gnomAD
CA6960095 rs79846574	469	Q>K		No	ClinGen ExAC gnomAD
CA6960094 rs146846076	471	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs372346993 CA6960093	472	P>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs754738116 CA6960091	477	M>V		No	ClinGen ExAC gnomAD
CA6960090 rs753681912	478	T>A		No	ClinGen ExAC gnomAD
CA6960089 rs766003101	478	T>I		No	ClinGen ExAC gnomAD
rs1367613551 CA387922486	479	V>G		No	ClinGen gnomAD
CA387922483 rs1242596090	480	L>M		No	ClinGen TOPMed
rs1187999008 CA387922462	483	N>D		No	ClinGen gnomAD
CA387922459 rs1465800722	483	N>T		No	ClinGen TOPMed
CA387922454 rs1269446815	484	V>I		No	ClinGen TOPMed gnomAD
CA387922441 CA6960088 rs369423492	485	M>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA387922448 rs1240732947	485	M>V		No	ClinGen TOPMed
TCGA novel	487	Q>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA387922429 rs1172831088	487	Q>H		No	ClinGen TOPMed
rs749880705 CA6960087	489	Q>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1219513952 CA387922406	491	A>T		No	ClinGen TOPMed gnomAD
CA6960086 rs766946264	491	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA6960083 rs376481585	492	G>D		No	ClinGen ESP ExAC TOPMed gnomAD
rs149160961 CA6960082	493	S>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs921953794 CA248396710	494	P>S		No	ClinGen TOPMed gnomAD
rs777083535 CA6960079	497	I>V		No	ClinGen ExAC TOPMed gnomAD
CA387922356 rs1389961820	499	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA6960077 rs781286344	500	G>C		No	ClinGen ExAC gnomAD
rs770947022 CA6960076	500	G>D		No	ClinGen ExAC gnomAD
CA387922318 rs1329868020	505	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA387922320 COSM4152771 rs1370955264	505	Q>L	kidney [Cosmic]	No	ClinGen cosmic curated gnomAD
CA387922304 rs1593344181	507	V>G		No	ClinGen Ensembl
CA387922309 rs1566162420	507	V>I		No	ClinGen Ensembl
rs544414935 CA6960075	509	T>I		No	ClinGen ExAC TOPMed gnomAD
rs544414935 CA248396659	509	T>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	510	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1264642493 CA387922280	511	N>H		No	ClinGen gnomAD
CA6960074 rs778799774	511	N>S		No	ClinGen ExAC gnomAD
TCGA novel	513	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA387922190 rs1566162399	517	N>D		No	ClinGen Ensembl
CA248396648 rs200709823	517	N>S		No	ClinGen TOPMed
CA6960073 rs754966367	519	T>I		No	ClinGen ExAC TOPMed gnomAD
rs779828314 CA248396641	520	V>I		No	ClinGen ExAC TOPMed gnomAD
rs779828314 CA6960071	520	V>L		No	ClinGen ExAC TOPMed gnomAD
CA248396634 rs1014836006	521	S>N		No	ClinGen TOPMed gnomAD
CA6960070 rs755730886	525	S>C		No	ClinGen ExAC gnomAD
TCGA novel	526	P>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1218181125 CA387922084	526	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA387922037 rs1221787504	529	S>C		No	ClinGen TOPMed gnomAD
TCGA novel	529	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs983729168 CA248396595	530	A>T		No	ClinGen TOPMed gnomAD
CA6960067 rs756688094	531	T>A		No	ClinGen ExAC TOPMed gnomAD
CA387922014 rs1394141475	531	T>I		No	ClinGen TOPMed gnomAD
rs751176591 CA6960066	533	P>S		No	ClinGen ExAC gnomAD
rs145271496 CA6960065	534	V>A		No	ClinGen ESP ExAC gnomAD
CA6960064 rs763561270	535	V>M		No	ClinGen ExAC TOPMed gnomAD
CA6960063 rs538458962	540	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
CA6960062 rs765543962	540	R>H		No	ClinGen ExAC TOPMed gnomAD
CA387921909 rs1453844435	541	S>G		No	ClinGen TOPMed gnomAD
CA6960061 rs759765268	541	S>R		No	ClinGen ExAC gnomAD
rs776686002 CA6960060	543	Q>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs186378801 CA6960059	543	Q>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6960058 rs200335001	548	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6960057 rs773346594	550	G>D		No	ClinGen ExAC TOPMed gnomAD
CA387921851 rs773346594	550	G>V		No	ClinGen ExAC TOPMed gnomAD
rs150015002 CA6960056	551	T>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs566775364 CA6960055	552	V>A		No	ClinGen ExAC TOPMed gnomAD
CA387921828 rs1221326485	554	T>I		No	ClinGen TOPMed
rs1333917173 CA387921824	555	S>*		No	ClinGen gnomAD
rs1308215258 CA387921820	556	V>L		No	ClinGen gnomAD
rs779846089 CA6960054	557	I>N		No	ClinGen ExAC TOPMed gnomAD
rs779846089 CA387921812	557	I>T		No	ClinGen ExAC TOPMed gnomAD
CA387921793 rs1401998658	559	T>A		No	ClinGen gnomAD
rs1593344056 CA387921786	559	T>I		No	ClinGen Ensembl
CA248396542 rs201257827	562	T>A		No	ClinGen 1000Genomes gnomAD
CA248396538 rs371226401	564	T>A		No	ClinGen ESP TOPMed
rs1413393425 CA387921751	564	T>I		No	ClinGen gnomAD
CA387921746 rs1402218970	565	L>P		No	ClinGen gnomAD
TCGA novel	565	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs113918519 CA248396534	566	T>I		No	ClinGen Ensembl
CA387921733 rs1473088756	567	Q>H		No	ClinGen TOPMed
rs1593344020 CA387921690	573	E>A		No	ClinGen Ensembl
CA6960050 rs780698708	575	E>G		No	ClinGen ExAC gnomAD
rs993468301 CA248396490	577	H>R		No	ClinGen Ensembl
CA6960049 rs757006030	577	H>Y		No	ClinGen ExAC gnomAD
rs751049840 CA6960048	578	L>F		No	ClinGen ExAC gnomAD
CA6960045 rs753290056	580	E>G		No	ClinGen ExAC gnomAD
CA6960046 rs758927037	580	E>K		No	ClinGen ExAC gnomAD
TCGA novel	580	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs139235167 CA6960042	581	N>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs759798230 CA6960043	581	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1037748924 CA248396452	582	T>A		No	ClinGen TOPMed
rs760888951 CA6960040	584	K>E		No	ClinGen ExAC gnomAD
CA387921609 rs1378908913	585	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs772158393 CA6960038	586	E>G		No	ClinGen ExAC TOPMed gnomAD
CA6960037 rs749181243	587	Q>E		No	ClinGen ExAC gnomAD
rs1335563866 CA387921596	587	Q>P		No	ClinGen gnomAD
rs775255614 CA6960036	588	Q>E		No	ClinGen ExAC gnomAD
TCGA novel	588	Q>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs368677066 CA6960035	589	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA6960034 rs745649341	590	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs1420680961 CA387921576	590	Q>L		No	ClinGen gnomAD
TCGA novel	590	Q>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1180483974 CA387921561	592	Y>*		No	ClinGen gnomAD
rs781050561 CA6960032	594	M>V		No	ClinGen ExAC TOPMed gnomAD
CA6960031 rs770653203	595	V>I		No	ClinGen ExAC gnomAD
CA6960030 rs746685386	598	S>R		No	ClinGen ExAC gnomAD
CA387921518 rs1245768304	599	S>Y		No	ClinGen TOPMed
CA6960029 rs777380082	600	N>S		No	ClinGen ExAC TOPMed gnomAD
rs1217171142 CA387921513	600	N>Y		No	ClinGen gnomAD
TCGA novel	601	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs757952607 CA6960028	603	T>A		No	ClinGen ExAC gnomAD
rs752304913 CA6960027	603	T>I		No	ClinGen ExAC TOPMed gnomAD
CA6960026 rs779275273	604	S>F		No	ClinGen ExAC gnomAD
rs755575705 CA6960025	605	Q>*		No	ClinGen ExAC gnomAD
CA6960024 rs754084704	605	Q>H		No	ClinGen ExAC gnomAD
rs1193651831 CA387921482	605	Q>R		No	ClinGen TOPMed
CA248396405 rs1052153245	607	A>V		No	ClinGen TOPMed gnomAD
CA387921466 rs1298292543	608	M>T		No	ClinGen gnomAD
rs766778099 CA6960023	608	M>V		No	ClinGen ExAC gnomAD
rs933232018 CA248396392	609	K>R		No	ClinGen Ensembl
CA387921437 rs147878914	612	E>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs144467943 CA6960020	612	E>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs140656224 CA6960019	612	E>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA6960021 rs147878914	612	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1414765344 CA387921430	613	L>Q		No	ClinGen gnomAD
CA248396345 rs1052070375	616	P>L		No	ClinGen TOPMed

No associated diseases with P32519

6 regional properties for P32519

Type	Name	Position	InterPro Accession
domain	Protein kinase domain	191 - 453	IPR000719
domain	AGC-kinase, C-terminal	454 - 533	IPR000961
domain	Pleckstrin homology domain	558 - 654	IPR001849
active_site	Serine/threonine-protein kinase, active site	313 - 325	IPR008271
domain	RGS domain	54 - 175	IPR016137
binding_site	Protein kinase, ATP binding site	197 - 220	IPR017441

Functions

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

3 GO annotations of cellular component

Name	Definition
chromatin	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

5 GO annotations of molecular function

Name	Definition
DNA-binding transcription activator activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
DNA-binding transcription factor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.
sequence-specific double-stranded DNA binding	Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.

6 GO annotations of biological process

Name	Definition
cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
negative regulation of T cell receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
positive regulation of DNA-templated transcription	Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
positive regulation of transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
regulation of cytokine production	Any process that modulates the frequency, rate, or extent of production of a cytokine.
regulation of transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

25 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q58DT0	ELF5	ETS-related transcription factor Elf-5	Bos taurus (Bovine)	SS
Q0VC65	ETV6	Transcription factor ETV6	Bos taurus (Bovine)	SS
Q9Y603	ETV7	Transcription factor ETV7	Homo sapiens (Human)	SS
P41212	ETV6	Transcription factor ETV6	Homo sapiens (Human)	SS
P78545	ELF3	ETS-related transcription factor Elf-3	Homo sapiens (Human)	SS
Q9UKW6	ELF5	ETS-related transcription factor Elf-5	Homo sapiens (Human)	EV
Q99607	ELF4	ETS-related transcription factor Elf-4	Homo sapiens (Human)	PR
Q06546	GABPA	GA-binding protein alpha chain	Homo sapiens (Human)	SS
O95238	SPDEF	SAM pointed domain-containing Ets transcription factor	Homo sapiens (Human)	PR
P50548	ERF	ETS domain-containing transcription factor ERF	Homo sapiens (Human)	PR
P41162	ETV3	ETS translocation variant 3	Homo sapiens (Human)	PR
P11308	ERG	Transcriptional regulator ERG	Homo sapiens (Human)	EV
P43268	ETV4	ETS translocation variant 4	Homo sapiens (Human)	EV
P41161	ETV5	ETS translocation variant 5	Homo sapiens (Human)	SS
P50549	ETV1	ETS translocation variant 1	Homo sapiens (Human)	EV
P41970	ELK3	ETS domain-containing protein Elk-3	Homo sapiens (Human)	SS
P28324	ELK4	ETS domain-containing protein Elk-4	Homo sapiens (Human)	EV
P19419	ELK1	ETS domain-containing protein Elk-1	Homo sapiens (Human)	EV
P15036	ETS2	Protein C-ets-2	Homo sapiens (Human)	EV
P14921	ETS1	Protein C-ets-1	Homo sapiens (Human)	EV
Q8VDK3	Elf5	ETS-related transcription factor Elf-5	Mus musculus (Mouse)	SS
P97360	Etv6	Transcription factor ETV6	Mus musculus (Mouse)	EV
Q9JHC9	Elf2	ETS-related transcription factor Elf-2	Mus musculus (Mouse)	PR
Q9Z2U4	Elf4	ETS-related transcription factor Elf-4	Mus musculus (Mouse)	PR
Q60775	Elf1	ETS-related transcription factor Elf-1	Mus musculus (Mouse)	PR

10	20	30	40	50	60
MAAVVQQNDL	VFEFASNVME	DERQLGDPAI	FPAVIVEHVP	GADILNSYAG	LACVEEPNDM
70	80	90	100	110	120
ITESSLDVAE	EEIIDDDDDD	ITLTVEASCH	DGDETIETIE	AAEALLNMDS	PGPMLDEKRI
130	140	150	160	170	180
NNNIFSSPED	DMVVAPVTHV	SVTLDGIPEV	METQQVQEKY	ADSPGASSPE	QPKRKKGRKT
190	200	210	220	230	240
KPPRPDSPAT	TPNISVKKKN	KDGKGNTIYL	WEFLLALLQD	KATCPKYIKW	TQREKGIFKL
250	260	270	280	290	300
VDSKAVSRLW	GKHKNKPDMN	YETMGRALRY	YYQRGILAKV	EGQRLVYQFK	EMPKDLIYIN
310	320	330	340	350	360
DEDPSSSIES	SDPSLSSSAT	SNRNQTSRSR	VSSSPGVKGG	ATTVLKPGNS	KAAKPKDPVE
370	380	390	400	410	420
VAQPSEVLRT	VQPTQSPYPT	QLFRTVHVVQ	PVQAVPEGEA	ARTSTMQDET	LNSSVQSIRT
430	440	450	460	470	480
IQAPTQVPVV	VSPRNQQLHT	VTLQTVPLTT	VIASTDPSAG	TGSQKFILQA	IPSSQPMTVL
490	500	510	520	530	540
KENVMLQSQK	AGSPPSIVLG	PAQVQQVLTS	NVQTICNGTV	SVASSPSFSA	TAPVVTFSPR
550	560	570	580	590	600
SSQLVAHPPG	TVITSVIKTQ	ETKTLTQEVE	KKESEDHLKE	NTEKTEQQPQ	PYVMVVSSSN
610
GFTSQVAMKQ	NELLEPNSF