P29775
Gene name |
Ets98B (ETS-4, CG5583) |
Protein name |
DNA-binding protein D-ETS-4 |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG5583 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P29775
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P29775-F1 | Predicted | AlphaFoldDB |
No variants for P29775
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P29775 | |||||
No associated diseases with P29775
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q04688 | Ets97D | DNA-binding protein Ets97D | Drosophila melanogaster (Fruit fly) | PR |
| O95238 | SPDEF | SAM pointed domain-containing Ets transcription factor | Homo sapiens (Human) | PR |
| Q9WTP3 | Spdef | SAM pointed domain-containing Ets transcription factor | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEYEKMLYMP | AASEMPHSPQ | LKPHQFQAHT | PTDQYSSYAD | NFDLSLLPQE | SASIPTTVFQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YNAPQIKVEC | AWDSQPIQQQ | QQPTAPYTNP | SSHQLIPPPA | YPHSAYPSPQ | SSPLQSEFAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YGLGRFGGSY | DSLNSPSPSL | EAVSIKQELH | ILPPSPPESN | CETPSPRSSC | GESIKAEPLD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ADIESLIDLN | SLLQQQSLQS | PQNLQDTKPD | HQLLRECLED | TSFQKRHNLK | PLALESFIGG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LAEVRGDFEP | VISLALEHAK | READAICAEL | QISQDPNGWS | PAQVHAWLRS | TLAQFRLPPV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ADLELHFCEN | GAALALLSEE | EFVRRLPESG | STLHAQLEIW | KMAYADQPAH | QQHSQQSAST |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DHWPASYAMP | HLDLDYNEDS | EDDDDMEADA | QVAPLNGSTT | SPPATNASNG | GTATVKRPNG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GRTGGGGSHI | HLWQFLKELL | ASPQVNGTAI | RWIDRSKGIF | KIEDSVRVAK | LWGRRKNRPA |
| 490 | 500 | 510 | |||
| MNYDKLSRSI | RQYYKKGIMK | KTERSQRLVY | QFCHPYSQ |