P29383
PR
Gene name |
AGL3 (SEP4) |
Protein name |
Agamous-like MADS-box protein AGL3 |
Names |
Protein SEPALLATA 4 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G03710 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P29383
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P29383-F1 | Predicted | AlphaFoldDB |
29 variants for P29383
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_1129794_G_C | 58 | C>S | No | 1000Genomes | |
| tmp_2_1130646_A_G | 86 | K>R | No | 1000Genomes | |
| tmp_2_1130762_T_C | 102 | V>A | No | 1000Genomes | |
| tmp_2_1130883_G_C | 119 | E>Q | No | 1000Genomes | |
| tmp_2_1130893_T_C | 122 | V>A | No | 1000Genomes | |
| ENSVATH05232473 | 141 | S>F | No | 1000Genomes | |
| tmp_2_1131169_C_T | 164 | T>I | No | 1000Genomes | |
| tmp_2_1131187_G_A | 170 | R>K | No | 1000Genomes | |
| tmp_2_1131278_G_T | 175 | S>I | No | 1000Genomes | |
| ENSVATH10849587 | 188 | A>G | No | 1000Genomes | |
| ENSVATH10849588 | 190 | E>A | No | 1000Genomes | |
| tmp_2_1131327_A_C | 191 | Q>H | No | 1000Genomes | |
| ENSVATH05232476 | 194 | Q>E | No | 1000Genomes | |
| tmp_2_1131335_A_C | 194 | Q>P | No | 1000Genomes | |
| ENSVATH01629259 | 209 | P>L | No | 1000Genomes | |
| ENSVATH05232477 | 209 | P>S | No | 1000Genomes | |
| ENSVATH10849589 | 211 | I>M | No | 1000Genomes | |
| tmp_2_1131393_A_T | 213 | E>D | No | 1000Genomes | |
| tmp_2_1131407_A_T | 218 | K>M | No | 1000Genomes | |
| tmp_2_1131427_G_C | 225 | A>P | No | 1000Genomes | |
| ENSVATH10849594 | 231 | H>Y | No | 1000Genomes | |
| ENSVATH05232482 | 235 | N>I | No | 1000Genomes | |
| tmp_2_1131563_A_G | 238 | N>D | No | 1000Genomes | |
| tmp_2_1131566_G_A | 239 | A>T | No | 1000Genomes | |
| ENSVATH10849715 | 239 | A>V | No | 1000Genomes | |
| ENSVATH10849716 | 240 | T>S | No | 1000Genomes | |
| ENSVATH05232484 | 249 | V>F | No | 1000Genomes | |
| ENSVATH05232485 | 250 | N>D | No | 1000Genomes | |
| ENSVATH10849717 | 251 | G>E | No | 1000Genomes |
No associated diseases with P29383
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| protein dimerization activity | The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
8 GO annotations of biological process
| Name | Definition |
|---|---|
| carpel development | The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style. |
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| maintenance of floral meristem identity | The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate. |
| petal development | The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure. |
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| sepal development | The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure. |
| stamen development | The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A2VDZ3 | MEF2A | Myocyte-specific enhancer factor 2A | Bos taurus (Bovine) | SS |
| Q9W6U8 | MEF2A | Myocyte-specific enhancer factor 2A | Gallus gallus (Chicken) | SS |
| Q02078 | MEF2A | Myocyte-specific enhancer factor 2A | Homo sapiens (Human) | SS |
| Q06413 | MEF2C | Myocyte-specific enhancer factor 2C | Homo sapiens (Human) | EV |
| Q60929 | Mef2a | Myocyte-specific enhancer factor 2A | Mus musculus (Mouse) | SS |
| Q8CFN5 | Mef2c | Myocyte-specific enhancer factor 2C | Mus musculus (Mouse) | SS |
| A4UTP7 | MEF2C | Myocyte-specific enhancer factor 2C | Sus scrofa (Pig) | SS |
| A2ICN5 | MEF2A | Myocyte-specific enhancer factor 2A | Sus scrofa (Pig) | SS |
| A0A096MJY4 | Mef2c | Myocyte-specific enhancer factor 2C | Rattus norvegicus (Rat) | SS |
| Q2MJT0 | Mef2a | Myocyte-specific enhancer factor 2A | Rattus norvegicus (Rat) | SS |
| Q40702 | MADS2 | MADS-box transcription factor 2 | Oryza sativa subsp japonica (Rice) | PR |
| Q5K4R0 | MADS47 | MADS-box transcription factor 47 | Oryza sativa subsp japonica (Rice) | PR |
| Q655V4 | MADS30 | MADS-box transcription factor 30 | Oryza sativa subsp japonica (Rice) | PR |
| P35632 | AP3 | Floral homeotic protein APETALA 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q1PFA4 | AGL30 | Agamous-like MADS-box protein AGL30 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q683D7 | MAF5 | Protein MADS AFFECTING FLOWERING 5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FUY6 | J | MADS-box protein JOINTLESS | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGRGKVELKR | IENKINRQVT | FAKRRNGLLK | KAYELSVLCD | AEIALLIFSN | RGKLYEFCSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PSGMARTVDK | YRKHSYATMD | PNQSAKDLQD | KYQDYLKLKS | RVEILQHSQR | HLLGEELSEM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DVNELEHLER | QVDASLRQIR | STKARSMLDQ | LSDLKTKEEM | LLETNRDLRR | KLEDSDAALT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QSFWGSSAAE | QQQQHQQQQQ | GMSSYQSNPP | IQEAGFFKPL | QGNVALQMSS | HYNHNPANAT |
| 250 | |||||
| NSATTSQNVN | GFFPGWMV |