P27348
Gene name |
YWHAQ |
Protein name |
14-3-3 protein theta |
Names |
14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:10971 |
EC number |
|
Protein Class |
|

Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure

Activated structure

8 structures for P27348
Entry ID | Method | Resolution | Chain | Position | Source |
---|---|---|---|---|---|
2BTP | X-ray | 280 A | A/B | 1-234 | PDB |
5IQP | X-ray | 260 A | A/B | 1-245 | PDB |
6BCR | X-ray | 199 A | A/B/E/F | 1-245 | PDB |
6BD2 | X-ray | 290 A | A/B | 1-245 | PDB |
6BQT | X-ray | 280 A | A/B/D/E/G/H/J/K | 1-245 | PDB |
6KZG | X-ray | 200 A | A/B | 2-234 | PDB |
6KZH | X-ray | 265 A | A/B | 2-234 | PDB |
AF-P27348-F1 | Predicted | AlphaFoldDB |
135 variants for P27348
Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
---|---|---|---|---|---|
CA345870533 rs1201939077 |
2 | E>D | No |
ClinGen gnomAD |
|
CA345870526 rs1347601492 |
3 | K>N | No |
ClinGen gnomAD |
|
rs1161896547 CA345870527 |
3 | K>R | No |
ClinGen TOPMed |
|
rs1390448720 CA345870524 |
4 | T>A | No |
ClinGen TOPMed |
|
rs1256912617 CA345870520 |
4 | T>S | No |
ClinGen gnomAD |
|
CA345870511 rs761020810 |
5 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
rs1227391131 CA345870514 |
5 | E>G | No |
ClinGen TOPMed gnomAD |
|
rs1333653992 CA345870497 |
8 | Q>E | No |
ClinGen TOPMed |
|
CA345870484 rs1365202009 |
9 | K>N | No |
ClinGen TOPMed gnomAD |
|
rs776134213 CA1524093 |
10 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
CA345870482 rs1335699369 |
10 | A>T | No |
ClinGen gnomAD |
|
rs776134213 CA345870479 |
10 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
rs1404137243 CA345870476 |
11 | K>E | No |
ClinGen TOPMed gnomAD |
|
rs1404137243 CA345870477 |
11 | K>Q | No |
ClinGen TOPMed gnomAD |
|
rs1218968603 CA345870445 |
15 | Q>L | No |
ClinGen TOPMed |
|
CA345870437 rs1573011079 |
16 | A>V | No |
ClinGen Ensembl |
|
CA345870436 rs1388248788 |
17 | E>* | No |
ClinGen gnomAD |
|
TCGA novel | 19 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
CA1524089 rs770667690 |
20 | D>E | No |
ClinGen ExAC gnomAD |
|
rs774114759 CA1524091 |
20 | D>H | No |
ClinGen ExAC gnomAD |
|
rs774114759 CA1524090 |
20 | D>N | No |
ClinGen ExAC gnomAD |
|
CA345870408 rs1257357675 |
21 | D>N | No |
ClinGen gnomAD |
|
CA42693525 rs1020766289 |
24 | T>I | No |
ClinGen TOPMed gnomAD |
|
rs1277401819 CA345870364 |
27 | K>Q | No |
ClinGen gnomAD |
|
CA1524086 rs769631927 |
27 | K>R | No |
ClinGen ExAC gnomAD |
|
rs1167518482 CA345870354 |
28 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
rs1186066024 CA345870348 |
29 | V>E | No |
ClinGen TOPMed |
|
rs141887759 CA345870350 |
29 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
rs141887759 CA1524084 |
29 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
rs1445424650 CA345870346 |
30 | T>A | No |
ClinGen gnomAD |
|
rs758380692 CA1524083 |
31 | E>Q | No |
ClinGen ExAC gnomAD |
|
CA1524082 rs750464603 |
33 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
CA1524081 rs778991719 |
33 | G>V | No |
ClinGen ExAC gnomAD |
|
CA1524080 rs757416206 |
34 | A>P | No |
ClinGen ExAC gnomAD |
|
rs1558553670 CA345870318 |
34 | A>V | No |
ClinGen Ensembl |
|
CA345870316 rs1173245074 |
35 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
CA1524077 rs756561669 |
38 | N>T | No |
ClinGen ExAC gnomAD |
|
CA1524074 rs760149820 |
42 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
rs1254370439 CA345870254 |
44 | L>F | No |
ClinGen gnomAD |
|
CA345870207 rs1404463545 |
51 | V>M | No |
ClinGen TOPMed |
|
rs1394300626 CA345870202 |
52 | V>I | No |
ClinGen TOPMed |
|
rs1332147491 CA345870186 |
54 | G>A | No |
ClinGen TOPMed |
|
rs1284443542 CA345870181 |
55 | R>H | No |
ClinGen TOPMed gnomAD |
|
CA345870179 rs1284443542 |
55 | R>L | No |
ClinGen TOPMed gnomAD |
|
TCGA novel | 56 | R>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
rs776325430 CA1524067 |
58 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
CA345870159 rs1309583828 |
59 | W>R | No |
ClinGen gnomAD |
|
rs1410406554 CA345870151 |
60 | R>G | No |
ClinGen gnomAD |
|
rs960357310 CA42693522 |
61 | V>I | No |
ClinGen Ensembl |
|
rs746966183 CA1524065 |
64 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
CA42693521 rs982921555 |
66 | E>Q | No |
ClinGen Ensembl |
|
rs778901859 CA1524064 |
67 | Q>R | No |
ClinGen ExAC gnomAD |
|
rs749499495 CA1524062 |
71 | T>A | No |
ClinGen ExAC gnomAD |
|
CA345870072 rs1183336588 |
71 | T>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
rs11544465 CA42693520 |
73 | D>N | No |
ClinGen Ensembl |
|
rs756400871 COSM1532907 CA1524060 |
74 | K>R | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
rs1256127421 CA345870050 |
75 | K>E | No |
ClinGen TOPMed |
|
rs1452859677 CA345870032 |
77 | Q>R | No |
ClinGen gnomAD |
|
CA1524058 rs199958721 |
80 | K>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
rs1027369792 CA345870003 |
81 | D>E | No |
ClinGen gnomAD |
|
CA1524056 rs752112912 |
82 | Y>C | No |
ClinGen ExAC gnomAD |
|
TCGA novel | 83 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
rs1573010858 CA345869981 |
85 | K>Q | No |
ClinGen Ensembl |
|
CA1524055 rs774239040 |
85 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
rs1228772598 CA345869955 |
88 | S>F | No |
ClinGen gnomAD |
|
CA42693517 rs1037601336 |
92 | S>F | No |
ClinGen TOPMed gnomAD |
|
CA1524053 rs369852702 |
93 | I>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
rs1455899719 CA345869918 |
94 | C>S | No |
ClinGen gnomAD |
|
rs761396781 CA1524051 |
95 | T>N | No |
ClinGen ExAC TOPMed gnomAD |
|
rs1558541411 CA345871885 |
99 | E>Q | No |
ClinGen Ensembl |
|
CA345871820 rs1304828875 |
108 | N>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
rs775375833 CA1524026 |
108 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
rs185211853 CA1524025 |
110 | T>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
rs1043933165 CA42688730 |
110 | T>I | No |
ClinGen gnomAD |
|
rs1305026555 CA345871792 |
112 | P>L | No |
ClinGen gnomAD |
|
rs892847212 CA42688728 |
112 | P>T | No |
ClinGen Ensembl |
|
TCGA novel | 113 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
rs1353639482 CA345871671 |
129 | L>V | No |
ClinGen gnomAD |
|
rs1306741559 CA345871641 |
133 | A>V | No |
ClinGen TOPMed gnomAD |
|
CA345871622 rs1391534106 |
136 | D>G | No |
ClinGen gnomAD |
|
CA345871608 rs1168659382 |
138 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
CA1524022 rs769768341 |
140 | Q>* | No |
ClinGen ExAC gnomAD |
|
CA345871297 rs1286254245 |
140 | Q>H | No |
ClinGen TOPMed |
|
TCGA novel | 140 | Q>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
rs767312364 CA1524006 |
141 | T>M | No |
ClinGen ExAC gnomAD |
|
CA1524005 rs759450776 |
142 | I>V | No |
ClinGen ExAC gnomAD |
|
rs1052123960 CA42688372 |
147 | G>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
CA1524004 rs774221614 |
147 | G>R | No |
ClinGen ExAC gnomAD |
|
CA1524003 rs769900540 |
148 | A>T | No |
ClinGen ExAC gnomAD |
|
rs371354151 CA1524001 |
152 | A>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
CA345871221 rs371354151 |
152 | A>T | No |
ClinGen ESP ExAC gnomAD |
|
rs1266699218 CA345871214 |
153 | F>V | No |
ClinGen gnomAD |
|
rs1351421945 CA345871195 |
155 | I>M | No |
ClinGen gnomAD |
|
rs768956586 CA1524000 |
155 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
CA345871180 rs201487177 |
157 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen 1000Genomes NCI-TCGA TOPMed |
rs199515928 CA42688370 |
158 | K>E | No |
ClinGen 1000Genomes |
|
rs927603470 TCGA novel CA42688368 |
159 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen TOPMed NCI-TCGA |
CA345871154 rs1452635609 |
161 | Q>E | No |
ClinGen TOPMed |
|
rs780502121 CA1523999 |
161 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
rs772387887 CA1523997 |
162 | P>S | No |
ClinGen ExAC gnomAD |
|
rs1461697218 CA345871133 |
164 | H>R | No |
ClinGen gnomAD |
|
rs200884745 CA1523995 |
166 | I>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
rs1000606168 CA42688367 |
167 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
CA1523993 rs367832498 |
167 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
rs367832498 CA1523994 |
167 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
COSM95553 rs1464445429 CA345871038 |
179 | Y>C | breast [Cosmic] | No |
ClinGen cosmic curated gnomAD |
TCGA novel | 184 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
rs1210769232 CA345870996 |
185 | P>S | No |
ClinGen TOPMed gnomAD |
|
rs1210769232 CA345870994 |
185 | P>T | No |
ClinGen TOPMed gnomAD |
|
rs1255736501 CA345870986 |
186 | E>G | No |
ClinGen gnomAD |
|
CA1523986 rs150523147 |
190 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
rs1441015148 CA345870950 |
192 | A>S | No |
ClinGen gnomAD |
|
CA1523984 rs776796788 |
193 | K>R | No |
ClinGen ExAC gnomAD |
|
rs377175915 CA1523960 |
195 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
rs1388450246 CA345870886 |
199 | A>V | No |
ClinGen gnomAD |
|
rs1410576904 CA345870880 |
200 | I>M | No |
ClinGen TOPMed |
|
rs774523757 CA1523959 |
200 | I>V | No |
ClinGen ExAC gnomAD |
|
CA1523957 rs749789995 |
205 | T>I | No |
ClinGen ExAC gnomAD |
|
CA1523958 rs749789995 |
205 | T>K | No |
ClinGen ExAC gnomAD |
|
rs1185622539 CA345870844 |
206 | L>P | No |
ClinGen gnomAD |
|
rs1444517962 CA345870824 |
209 | D>Y | No |
ClinGen gnomAD |
|
CA1523956 rs773765562 |
211 | Y>F | No |
ClinGen ExAC |
|
CA1523955 rs769267624 |
215 | T>I | No |
ClinGen ExAC gnomAD |
|
TCGA novel | 217 | I>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
rs896145482 CA42688300 |
221 | L>F | No |
ClinGen Ensembl |
|
rs747693562 CA1523954 |
224 | N>D | No |
ClinGen ExAC gnomAD |
|
CA1523933 rs762328022 |
232 | S>T | No |
ClinGen ExAC TOPMed gnomAD |
|
CA345870630 rs1321647925 |
235 | E>K | No |
ClinGen gnomAD |
|
CA1523929 rs746631800 |
237 | C>G | No |
ClinGen ExAC gnomAD |
|
rs1455995513 CA345870604 |
238 | D>E | No |
ClinGen gnomAD |
|
rs779806817 CA1523928 |
238 | D>V | No |
ClinGen ExAC gnomAD |
|
rs200376025 CA1523927 |
239 | A>G | No |
ClinGen ExAC gnomAD |
|
CA1523926 rs200376025 |
239 | A>V | No |
ClinGen ExAC gnomAD |
|
rs757206430 CA1523924 |
242 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
CA1523923 rs753821484 |
243 | A>V | No |
ClinGen ExAC gnomAD |
No associated diseases with P27348
3 regional properties for P27348
Type | Name | Position | InterPro Accession |
---|---|---|---|
conserved_site | 14-3-3 protein, conserved site | 41 - 51 | IPR023409-1 |
conserved_site | 14-3-3 protein, conserved site | 211 - 230 | IPR023409-2 |
domain | 14-3-3 domain | 3 - 242 | IPR023410 |
6 GO annotations of cellular component
Name | Definition |
---|---|
cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
extracellular exosome | A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. |
focal adhesion | A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). |
membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
3 GO annotations of molecular function
Name | Definition |
---|---|
identical protein binding | Binding to an identical protein or proteins. |
protein domain specific binding | Binding to a specific domain of a protein. |
protein N-terminus binding | Binding to a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. |
6 GO annotations of biological process
Name | Definition |
---|---|
negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
protein localization | Any process in which a protein is transported to, or maintained in, a specific location. |
protein targeting | The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. |
signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
small GTPase mediated signal transduction | The series of molecular signals in which a small monomeric GTPase relays a signal. |
substantia nigra development | The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). |
37 homologous proteins in AiPD
UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
---|---|---|---|---|
P61981 | YWHAG | 14-3-3 protein gamma | Homo sapiens (Human) | PR |
Q04917 | YWHAH | 14-3-3 protein eta | Homo sapiens (Human) | PR |
P63104 | YWHAZ | 14-3-3 protein zeta/delta | Homo sapiens (Human) | PR |
P31946 | YWHAB | 14-3-3 protein beta/alpha | Homo sapiens (Human) | PR |
P49106 | GRF1 | 14-3-3-like protein GF14-6 | Zea mays (Maize) | PR |
P68510 | Ywhah | 14-3-3 protein eta | Mus musculus (Mouse) | PR |
P63101 | Ywhaz | 14-3-3 protein zeta/delta | Mus musculus (Mouse) | PR |
P93784 | HOX | 14-3-3-like protein 16R | Solanum tuberosum (Potato) | PR |
Q41418 | 14-3-3-like protein | Solanum tuberosum (Potato) | PR | |
P63102 | Ywhaz | 14-3-3 protein zeta/delta | Rattus norvegicus (Rat) | PR |
Q6EUP4 | GF14E | 14-3-3-like protein GF14-E | Oryza sativa subsp japonica (Rice) | PR |
Q06967 | GF14F | 14-3-3-like protein GF14-F | Oryza sativa subsp japonica (Rice) | PR |
Q7XTE8 | GF14B | 14-3-3-like protein GF14-B | Oryza sativa subsp japonica (Rice) | PR |
Q6ZKC0 | GF14C | 14-3-3-like protein GF14-C | Oryza sativa subsp japonica (Rice) | PR |
Q84J55 | GF14A | 14-3-3-like protein GF14-A | Oryza sativa subsp japonica (Rice) | PR |
Q2R2W2 | GF14D | 14-3-3-like protein GF14-D | Oryza sativa subsp japonica (Rice) | PR |
Q2R1D5 | GF14H | Putative 14-3-3-like protein GF14-H | Oryza sativa subsp japonica (Rice) | PR |
Q96450 | GF14A | 14-3-3-like protein A | Glycine max (Soybean) (Glycine hispida) | PR |
Q96453 | GF14D | 14-3-3-like protein D | Glycine max (Soybean) (Glycine hispida) | PR |
Q96452 | GF14C | 14-3-3-like protein C | Glycine max (Soybean) (Glycine hispida) | PR |
Q9C5W6 | GRF12 | 14-3-3-like protein GF14 iota | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q9S9Z8 | GRF11 | 14-3-3-like protein GF14 omicron | Arabidopsis thaliana (Mouse-ear cress) | PR |
P46077 | GRF4 | 14-3-3-like protein GF14 phi | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q01525 | GRF2 | 14-3-3-like protein GF14 omega | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q96300 | GRF7 | 14-3-3-like protein GF14 nu | Arabidopsis thaliana (Mouse-ear cress) | PR |
P42645 | GRF5 | 14-3-3-like protein GF14 upsilon | Arabidopsis thaliana (Mouse-ear cress) | PR |
P42644 | GRF3 | 14-3-3-like protein GF14 psi | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q96299 | GRF9 | 14-3-3-like protein GF14 mu | Arabidopsis thaliana (Mouse-ear cress) | PR |
P42652 | TFT4 | 14-3-3 protein 4 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93212 | TFT7 | 14-3-3 protein 7 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93209 | TFT3 | 14-3-3 protein 3 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93207 | TFT10 | 14-3-3 protein 10 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93211 | TFT6 | 14-3-3 protein 6 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93206 | TFT1 | 14-3-3 protein 1 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93208 | TFT2 | 14-3-3 protein 2 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93213 | TFT8 | 14-3-3 protein 8 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
P93214 | TFT9 | 14-3-3 protein 9 | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | PR |
10 | 20 | 30 | 40 | 50 | 60 |
MEKTELIQKA | KLAEQAERYD | DMATCMKAVT | EQGAELSNEE | RNLLSVAYKN | VVGGRRSAWR |
70 | 80 | 90 | 100 | 110 | 120 |
VISSIEQKTD | TSDKKLQLIK | DYREKVESEL | RSICTTVLEL | LDKYLIANAT | NPESKVFYLK |
130 | 140 | 150 | 160 | 170 | 180 |
MKGDYFRYLA | EVACGDDRKQ | TIDNSQGAYQ | EAFDISKKEM | QPTHPIRLGL | ALNFSVFYYE |
190 | 200 | 210 | 220 | 230 | 240 |
ILNNPELACT | LAKTAFDEAI | AELDTLNEDS | YKDSTLIMQL | LRDNLTLWTS | DSAGEECDAA |
EGAEN |