Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P25766

Entry ID Method Resolution Chain Position Source
AF-P25766-F1 Predicted AlphaFoldDB

No variants for P25766

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P25766

No associated diseases with P25766

1 regional properties for P25766

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 18 - 175 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endosome A vacuole to which materials ingested by endocytosis are delivered.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5ZHV1 RAB33B Ras-related protein Rab-33B Gallus gallus (Chicken) PR
Q96AX2 RAB37 Ras-related protein Rab-37 Homo sapiens (Human) PR
Q9H082 RAB33B Ras-related protein Rab-33B Homo sapiens (Human) PR
Q9JKM7 Rab37 Ras-related protein Rab-37 Mus musculus (Mouse) PR
O35963 Rab33b Ras-related protein Rab-33B Mus musculus (Mouse) PR
Q20365 rab-33 Ras-related protein Rab-33 Caenorhabditis elegans PR
Q9FE79 RABA4C Ras-related protein RABA4c Arabidopsis thaliana (Mouse-ear cress) PR
Q9LH50 RABA4D Ras-related protein RABA4d Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSRGGGSYGE VGQKIDYVFK VVLIGDSAVG KSQLLARFAR NEFNLDSKAT IGVEFQTRTL
70 80 90 100 110 120
HIDARTVKAQ IWDTAGQERY RAVTSAYYRG AVGAMLVYDI TKRQSFDHVA RWLEELRGHA
130 140 150 160 170 180
DKNIVIMLIG NKSDLGTLRV VPTEDAKEFA ERENLFFMET SALESTNVEN AFMTVLTEIY
190 200 210 220
RIVSKKNLVA NEEVDSSGNS SLLKGTKIVV PGQEPAPPTK ASCCMS