P17028
PR
Gene name |
ZNF24 (KOX17, ZNF191, ZSCAN3) |
Protein name |
Zinc finger protein 24 |
Names |
Retinoic acid suppression protein A, RSG-A, Zinc finger and SCAN domain-containing protein 3, Zinc finger protein 191, Zinc finger protein KOX17 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:7572 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for P17028
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1X6E | NMR | - | A | 272-330 | PDB |
| 3LHR | X-ray | 190 A | A/B | 46-136 | PDB |
| AF-P17028-F1 | Predicted | AlphaFoldDB |
209 variants for P17028
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs762122893 CA298618585 |
3 | A>V | No |
ClinGen Ensembl |
|
|
CA298618584 rs186299878 |
4 | Q>* | No |
ClinGen 1000Genomes |
|
|
CA402279882 rs186299878 |
4 | Q>E | No |
ClinGen 1000Genomes |
|
|
CA402279878 rs1432292612 |
4 | Q>R | No |
ClinGen gnomAD |
|
|
rs767336323 CA8937398 |
7 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA8937396 rs774013885 |
8 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA8937397 rs761727452 |
8 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs768434014 CA8937395 |
9 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937394 rs368633915 |
11 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs775237703 CA8937393 |
13 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs147223874 CA298618583 |
15 | P>Q | No |
ClinGen ESP gnomAD |
|
|
CA402279706 rs1413337498 |
17 | P>A | No |
ClinGen TOPMed |
|
|
CA402279681 rs1445525762 |
18 | D>E | No |
ClinGen TOPMed |
|
|
CA402279686 rs1424488976 |
18 | D>G | No |
ClinGen gnomAD |
|
|
CA8937390 rs745335900 |
20 | E>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 23 | I>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs777052748 CA8937389 |
23 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1239413180 CA402279595 |
24 | L>P | No |
ClinGen gnomAD |
|
| TCGA novel | 25 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1388694123 CA402279584 |
25 | R>S | No |
ClinGen gnomAD |
|
|
rs1442133988 CA402279573 |
26 | V>A | No |
ClinGen gnomAD |
|
|
CA8937388 rs771326930 |
26 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA8937386 rs778002882 |
27 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA8937387 rs181928710 |
27 | K>T | No |
ClinGen 1000Genomes ExAC |
|
|
rs367586570 CA8937385 |
31 | D>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1417735032 CA402279525 |
31 | D>V | No |
ClinGen TOPMed |
|
|
rs1356991672 CA402279510 |
33 | D>E | No |
ClinGen gnomAD |
|
|
CA8937384 rs748391300 |
33 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA402279504 rs1303001384 |
34 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
CA8937382 rs755100949 |
35 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937380 rs576230662 |
37 | G>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8937381 rs753850709 |
37 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs1422819005 CA402279484 |
38 | S>P | No |
ClinGen gnomAD |
|
|
CA8937378 rs751459673 |
40 | I>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937379 rs757148413 |
40 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1246310310 CA402279461 |
41 | P>R | No |
ClinGen TOPMed |
|
|
CA8937376 rs762800880 |
44 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs764006836 CA8937377 |
44 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937375 rs374877566 |
46 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA402279426 rs374877566 |
46 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8937373 rs556074473 |
49 | E>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA402279390 rs1252488979 |
51 | F>L | No |
ClinGen gnomAD |
|
| TCGA novel | 52 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA298618582 rs757349943 |
52 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs775997988 CA402279382 |
53 | Q>P | No |
ClinGen ExAC gnomAD |
|
|
CA8937372 rs775997988 |
53 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs770405655 CA8937371 |
54 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1208438390 CA402279355 |
57 | Q>R | No |
ClinGen TOPMed |
|
| TCGA novel | 58 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8937370 rs747482316 |
60 | Y>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 67 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 67 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs748489570 CA8937367 |
68 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA8937368 rs772456362 |
68 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs773718175 CA8937369 |
68 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA402279256 rs1399470227 |
72 | Q>R | No |
ClinGen gnomAD |
|
|
rs779164395 CA8937366 |
74 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1464159015 CA402279217 |
78 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs755190883 CA8937365 |
78 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 82 | R>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8937363 rs537551804 |
85 | T>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs148457418 CA8937362 |
85 | T>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 88 | K>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1331916233 CA402279147 |
89 | E>K | No |
ClinGen TOPMed |
|
| TCGA novel | 89 | E>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 95 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs752523836 CA8937358 |
98 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA402279053 rs1203724271 |
102 | A>V | No |
ClinGen gnomAD |
|
|
CA8937355 rs776287835 |
103 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs985934020 CA298618577 |
109 | Q>R | No |
ClinGen TOPMed |
|
|
CA8937352 rs551820427 |
110 | T>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8937351 rs772555800 |
110 | T>S | No |
ClinGen ExAC gnomAD |
|
|
COSM988142 rs1307017653 CA402278986 |
113 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1462058893 CA402278971 |
115 | H>R | No |
ClinGen TOPMed |
|
|
rs201180095 CA298618575 |
116 | H>L | No |
ClinGen Ensembl |
|
|
rs762234105 CA8937350 |
116 | H>Y | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 118 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA298618574 rs1020119808 |
118 | E>Q | No |
ClinGen gnomAD |
|
| TCGA novel | 120 | G>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1569103845 CA402278910 |
124 | V>L | No |
ClinGen Ensembl |
|
|
rs1481981914 CA402278896 |
126 | V>E | No |
ClinGen gnomAD |
|
|
CA402278886 rs1420719943 |
128 | E>A | No |
ClinGen gnomAD |
|
|
CA8937345 rs769809099 |
132 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs1236579304 CA402278853 |
132 | S>T | No |
ClinGen TOPMed |
|
|
CA402278831 rs1457530848 |
135 | D>E | No |
ClinGen TOPMed |
|
|
rs745933929 CA8937344 |
138 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937343 rs186145654 |
140 | P>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8937324 rs775619842 |
142 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA8937323 rs148053646 |
143 | L>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs746008107 CA8937322 |
144 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 144 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA8937321 COSM1388567 rs781423777 |
145 | R>Q | large_intestine Variant assessed as Somatic; 9.246e-05 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
| TCGA novel | 146 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771074537 CA8937320 |
146 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA402278748 rs748116563 |
148 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs144569334 CA8937318 |
148 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs144569334 CA8937317 |
148 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA8937319 rs748116563 COSM1233747 |
148 | R>W | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA402278743 rs1471635452 |
149 | E>G | No |
ClinGen TOPMed |
|
|
rs1374424615 CA402278745 |
149 | E>K | No |
ClinGen TOPMed |
|
|
rs1374424615 CA402278746 |
149 | E>Q | No |
ClinGen TOPMed |
|
|
rs779641218 CA402278736 |
150 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937315 rs779641218 |
150 | V>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937316 rs753654830 |
150 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA402278727 rs1219316822 |
152 | V>I | No |
ClinGen gnomAD |
|
|
rs755796361 CA8937314 |
154 | D>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 154 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1398192796 CA402278705 |
155 | M>I | No |
ClinGen gnomAD |
|
|
CA8937313 rs750022218 |
155 | M>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs959479592 CA298618549 |
155 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
CA298618548 rs750022218 |
155 | M>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 156 | V>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs767038712 CA8937312 |
158 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA8937311 rs190032088 |
160 | E>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA402278668 rs1468740975 |
161 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA298618546 rs979460995 |
162 | Q>R | No |
ClinGen Ensembl |
|
|
rs1383122401 CA402278644 |
164 | L>F | No |
ClinGen TOPMed |
|
|
rs764645000 CA8937309 |
165 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs149270186 CA8937308 |
166 | S>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1189132216 CA402278634 |
166 | S>T | No |
ClinGen gnomAD |
|
|
CA8937307 rs775915731 COSM324447 |
168 | E>D | lung [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs1245569409 CA402278615 |
169 | L>F | No |
ClinGen TOPMed |
|
|
CA8937306 rs765450091 |
171 | A>G | No |
ClinGen ExAC gnomAD |
|
|
CA298618545 rs966649495 |
172 | V>M | No |
ClinGen Ensembl |
|
| TCGA novel | 179 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs372209559 CA8937304 |
183 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402278514 rs1258562998 |
183 | L>P | No |
ClinGen gnomAD |
|
|
rs747053513 CA8937302 |
184 | H>R | No |
ClinGen ExAC |
|
|
rs1247323137 CA402278474 |
189 | C>Y | No |
ClinGen gnomAD |
|
|
CA297812152 rs377377194 |
193 | G>S | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs749268230 CA8937278 |
203 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1239857201 CA402190102 |
204 | Q>R | No |
ClinGen gnomAD |
|
|
rs1349174458 CA402190089 |
205 | E>G | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA402190096 rs1569102593 |
205 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1233373476 CA402190064 |
207 | P>R | No |
ClinGen gnomAD |
|
|
rs534096794 CA8937276 |
211 | E>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8937275 rs745636628 |
213 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs1300726054 CA402190003 |
213 | H>Y | No |
ClinGen gnomAD |
|
|
CA402189984 rs1360764284 |
214 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA8937274 rs568622827 |
215 | V>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs746578932 CA8937272 |
218 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1266441689 CA402189936 |
219 | L>P | No |
ClinGen TOPMed |
|
|
CA297812144 rs548027190 |
220 | N>H | No |
ClinGen 1000Genomes |
|
|
rs2032729 CA402189926 |
220 | N>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
VAR_012017 rs2032729 CA8937270 |
220 | N>S | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA402189920 rs1598685292 |
221 | M>V | No |
ClinGen Ensembl |
|
|
rs1419868325 CA402189899 |
222 | G>D | No |
ClinGen gnomAD |
|
|
CA297812143 rs1041022361 |
223 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA402189884 rs753280888 |
224 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937269 rs753280888 |
224 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402189861 rs1423089710 |
226 | I>V | No |
ClinGen gnomAD |
|
|
CA8937268 rs568880273 |
228 | K>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA8937267 rs755443618 |
229 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402189808 rs1201582978 |
230 | G>A | No |
ClinGen gnomAD |
|
|
rs1344890679 CA402189742 |
234 | F>L | No |
ClinGen gnomAD |
|
|
CA8937265 rs145935120 |
237 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs750561326 CA8937263 |
238 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs750561326 CA8937264 |
238 | R>T | No |
ClinGen ExAC gnomAD |
|
|
rs945009926 CA297812135 |
240 | E>K | No |
ClinGen TOPMed |
|
| TCGA novel | 241 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 243 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM1157939 rs142376346 CA8937262 |
245 | P>S | pancreas [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA402189513 rs1428421513 |
247 | R>* | No |
ClinGen gnomAD |
|
|
CA8937259 rs369480225 |
247 | R>L | Variant assessed as Somatic; 4.623e-05 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA8937260 rs369480225 COSM988140 |
247 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA297812130 rs1045239708 |
251 | H>D | No |
ClinGen Ensembl |
|
|
rs1299961862 CA402189419 |
252 | I>T | No |
ClinGen TOPMed |
|
|
rs776419852 CA8937257 |
252 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937256 rs770658107 |
254 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA8937255 rs746700144 |
259 | H>L | No |
ClinGen ExAC gnomAD |
|
|
rs1186095857 CA402189057 |
268 | L>R | No |
ClinGen gnomAD |
|
|
rs1243712167 CA402188906 |
275 | G>V | No |
ClinGen TOPMed |
|
|
rs201828681 CA297812127 |
276 | E>G | No |
ClinGen 1000Genomes |
|
|
rs768716616 CA8937254 |
279 | Y>* | No |
ClinGen ExAC |
|
|
rs868331034 CA297812123 |
280 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1474538878 CA402188563 |
290 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA402188547 rs1356790875 |
291 | S>G | No |
ClinGen TOPMed |
|
|
CA402188509 rs1234421685 |
292 | S>C | No |
ClinGen gnomAD |
|
|
CA402188456 rs1340295864 |
295 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA402188374 CA402188377 rs1239625426 |
298 | Q>H | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 299 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771654475 CA8937252 |
300 | V>A | No |
ClinGen ExAC |
|
|
CA402188267 rs1598685072 |
305 | K>E | No |
ClinGen Ensembl |
|
|
rs1249372308 CA402188201 |
308 | K>N | No |
ClinGen TOPMed |
|
| TCGA novel | 308 | K>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs867997184 CA297812117 |
311 | E>D | No |
ClinGen Ensembl |
|
|
rs747590446 CA8937251 |
311 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1187471033 CA402188112 |
314 | K>E | No |
ClinGen TOPMed |
|
|
rs755546696 CA8937249 |
317 | S>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 318 | Q>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA402187995 rs1362861608 COSM264908 |
320 | S>L | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA402187978 rs1380883187 |
321 | G>E | No |
ClinGen gnomAD |
|
|
rs1446939713 CA402187865 |
328 | I>T | No |
ClinGen gnomAD |
|
|
rs1380493164 CA402187830 |
330 | T>I | No |
ClinGen gnomAD |
|
|
CA297812111 VAR_012018 rs3568 |
331 | G>W | No |
ClinGen UniProt Ensembl dbSNP |
|
|
rs1396781758 CA402187692 |
338 | V>A | No |
ClinGen gnomAD |
|
|
CA8937245 rs750695059 |
338 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA402187666 rs767608655 |
339 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA8937243 rs762007370 |
340 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs1284491319 CA402187600 |
343 | S>L | No |
ClinGen Ensembl |
|
|
rs868207356 CA297812104 |
352 | R>K | No |
ClinGen Ensembl |
|
|
rs1269410786 CA402187380 |
356 | R>K | No |
ClinGen TOPMed |
|
|
rs867844647 CA297812102 |
356 | R>S | No |
ClinGen Ensembl |
|
|
rs1323158517 CA402187339 |
358 | N>S | No |
ClinGen gnomAD |
|
|
CA8937236 rs772967511 |
363 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA402187200 rs1311147210 |
366 | V>G | No |
ClinGen gnomAD |
|
| TCGA novel | 367 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA629454393 rs1376062531 |
368 | V>K | No |
ClinGen gnomAD |
|
|
rs1428764908 CA402187158 |
369 | V>K | No |
ClinGen gnomAD |
No associated diseases with P17028
3 regional properties for P17028
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Heat shock protein 70, conserved site | 9 - 16 | IPR018181-1 |
| conserved_site | Heat shock protein 70, conserved site | 197 - 210 | IPR018181-2 |
| conserved_site | Heat shock protein 70, conserved site | 334 - 348 | IPR018181-3 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
6 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription activator activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II. |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| identical protein binding | Binding to an identical protein or proteins. |
| metal ion binding | Binding to a metal ion. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| myelination | The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. |
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
177 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08DS3 | OSR1 | Protein odd-skipped-related 1 | Bos taurus (Bovine) | PR |
| Q2VWH6 | FEZF2 | Fez family zinc finger protein 2 | Bos taurus (Bovine) | PR |
| A6QNZ0 | ZSCAN26 | Zinc finger and SCAN domain-containing protein 26 | Bos taurus (Bovine) | PR |
| A7MBI1 | ZFP69 | Zinc finger protein 69 homolog | Bos taurus (Bovine) | PR |
| Q08705 | CTCF | Transcriptional repressor CTCF | Gallus gallus (Chicken) | PR |
| O42409 | GFI1B | Zinc finger protein Gfi-1b | Gallus gallus (Chicken) | PR |
| A2T6W2 | ZNF449 | Zinc finger protein 449 | Pan troglodytes (Chimpanzee) | PR |
| Q9U405 | grau | Transcription factor grauzone | Drosophila melanogaster (Fruit fly) | PR |
| Q7K0S9 | sug | Zinc finger protein GLIS2 homolog | Drosophila melanogaster (Fruit fly) | PR |
| P20385 | Cf2 | Chorion transcription factor Cf2 | Drosophila melanogaster (Fruit fly) | PR |
| Q86P48 | ATbp | AT-rich binding protein | Drosophila melanogaster (Fruit fly) | PR |
| P28698 | MZF1 | Myeloid zinc finger 1 | Homo sapiens (Human) | PR |
| Q9NTW7 | ZFP64 | Zinc finger protein 64 | Homo sapiens (Human) | PR |
| P08151 | GLI1 | Zinc finger protein GLI1 | Homo sapiens (Human) | PR |
| Q9UFB7 | ZBTB47 | Zinc finger and BTB domain-containing protein 47 | Homo sapiens (Human) | PR |
| P18146 | EGR1 | Early growth response protein 1 | Homo sapiens (Human) | PR |
| Q9Y5W3 | KLF2 | Krueppel-like factor 2 | Homo sapiens (Human) | PR |
| Q96SZ4 | ZSCAN10 | Zinc finger and SCAN domain-containing protein 10 | Homo sapiens (Human) | PR |
| P57682 | KLF3 | Krueppel-like factor 3 | Homo sapiens (Human) | PR |
| P25490 | YY1 | Transcriptional repressor protein YY1 | Homo sapiens (Human) | SS |
| O43296 | ZNF264 | Zinc finger protein 264 | Homo sapiens (Human) | PR |
| P49711 | CTCF | Transcriptional repressor CTCF | Homo sapiens (Human) | PR |
| Q9NQX1 | PRDM5 | PR domain zinc finger protein 5 | Homo sapiens (Human) | PR |
| Q9HBE1 | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 | Homo sapiens (Human) | PR |
| Q8TAX0 | OSR1 | Protein odd-skipped-related 1 | Homo sapiens (Human) | PR |
| Q8TBJ5 | FEZF2 | Fez family zinc finger protein 2 | Homo sapiens (Human) | PR |
| Q96SR6 | ZNF382 | Zinc finger protein 382 | Homo sapiens (Human) | PR |
| Q9ULJ3 | ZBTB21 | Zinc finger and BTB domain-containing protein 21 | Homo sapiens (Human) | PR |
| O75840 | KLF7 | Krueppel-like factor 7 | Homo sapiens (Human) | PR |
| Q13127 | REST | RE1-silencing transcription factor | Homo sapiens (Human) | PR |
| Q8IZM8 | ZNF654 | Zinc finger protein 654 | Homo sapiens (Human) | PR |
| Q14526 | HIC1 | Hypermethylated in cancer 1 protein | Homo sapiens (Human) | PR |
| Q06889 | EGR3 | Early growth response protein 3 | Homo sapiens (Human) | PR |
| Q08ER8 | ZNF543 | Zinc finger protein 543 | Homo sapiens (Human) | PR |
| Q8N680 | ZBTB2 | Zinc finger and BTB domain-containing protein 2 | Homo sapiens (Human) | PR |
| O95625 | ZBTB11 | Zinc finger and BTB domain-containing protein 11 | Homo sapiens (Human) | PR |
| Q96BV0 | ZNF775 | Zinc finger protein 775 | Homo sapiens (Human) | PR |
| Q5FWF6 | ZNF789 | Zinc finger protein 789 | Homo sapiens (Human) | PR |
| Q05516 | ZBTB16 | Zinc finger and BTB domain-containing protein 16 | Homo sapiens (Human) | PR |
| Q9H116 | GZF1 | GDNF-inducible zinc finger protein 1 | Homo sapiens (Human) | PR |
| Q8IW36 | ZNF695 | Zinc finger protein 695 | Homo sapiens (Human) | PR |
| Q5VTD9 | GFI1B | Zinc finger protein Gfi-1b | Homo sapiens (Human) | PR |
| Q6PG37 | ZNF790 | Zinc finger protein 790 | Homo sapiens (Human) | PR |
| Q9NQV6 | PRDM10 | PR domain zinc finger protein 10 | Homo sapiens (Human) | PR |
| Q9Y2D9 | ZNF652 | Zinc finger protein 652 | Homo sapiens (Human) | PR |
| Q5TC79 | ZBTB37 | Zinc finger and BTB domain-containing protein 37 | Homo sapiens (Human) | PR |
| Q9Y4E5 | ZNF451 | E3 SUMO-protein ligase ZNF451 | Homo sapiens (Human) | PR |
| Q8ND82 | ZNF280C | Zinc finger protein 280C | Homo sapiens (Human) | PR |
| Q49AA0 | ZFP69 | Zinc finger protein 69 homolog | Homo sapiens (Human) | PR |
| O43298 | ZBTB43 | Zinc finger and BTB domain-containing protein 43 | Homo sapiens (Human) | PR |
| Q9Y330 | ZBTB12 | Zinc finger and BTB domain-containing protein 12 | Homo sapiens (Human) | PR |
| Q13105 | ZBTB17 | Zinc finger and BTB domain-containing protein 17 | Homo sapiens (Human) | PR |
| P51508 | ZNF81 | Zinc finger protein 81 | Homo sapiens (Human) | PR |
| Q5JNZ3 | ZNF311 | Zinc finger protein 311 | Homo sapiens (Human) | PR |
| Q9Y4X4 | KLF12 | Krueppel-like factor 12 | Homo sapiens (Human) | PR |
| P10074 | ZBTB48 | Telomere zinc finger-associated protein | Homo sapiens (Human) | PR |
| P17010 | ZFX | Zinc finger X-chromosomal protein | Homo sapiens (Human) | PR |
| Q9H5H4 | ZNF768 | Zinc finger protein 768 | Homo sapiens (Human) | PR |
| Q9Y2L8 | ZKSCAN5 | Zinc finger protein with KRAB and SCAN domains 5 | Homo sapiens (Human) | PR |
| Q86UZ6 | ZBTB46 | Zinc finger and BTB domain-containing protein 46 | Homo sapiens (Human) | PR |
| Q8NCP5 | ZBTB44 | Zinc finger and BTB domain-containing protein 44 | Homo sapiens (Human) | PR |
| P41182 | BCL6 | B-cell lymphoma 6 protein | Homo sapiens (Human) | PR |
| Q9NQX0 | PRDM6 | Putative histone-lysine N-methyltransferase PRDM6 | Homo sapiens (Human) | PR |
| Q9BU19 | ZNF692 | Zinc finger protein 692 | Homo sapiens (Human) | PR |
| Q08AG5 | ZNF844 | Zinc finger protein 844 | Homo sapiens (Human) | PR |
| Q6R2W3 | ZBED9 | SCAN domain-containing protein 3 | Homo sapiens (Human) | PR |
| P98182 | ZNF200 | Zinc finger protein 200 | Homo sapiens (Human) | PR |
| Q9UK11 | ZNF223 | Zinc finger protein 223 | Homo sapiens (Human) | PR |
| O15156 | ZBTB7B | Zinc finger and BTB domain-containing protein 7B | Homo sapiens (Human) | PR |
| Q6ZMS7 | ZNF783 | Zinc finger protein 783 | Homo sapiens (Human) | PR |
| P59923 | ZNF445 | Zinc finger protein 445 | Homo sapiens (Human) | PR |
| Q8N859 | ZNF713 | Zinc finger protein 713 | Homo sapiens (Human) | PR |
| Q99612 | KLF6 | Krueppel-like factor 6 | Homo sapiens (Human) | PR |
| Q8TD17 | ZNF398 | Zinc finger protein 398 | Homo sapiens (Human) | PR |
| P52739 | ZNF131 | Zinc finger protein 131 | Homo sapiens (Human) | PR |
| Q05215 | EGR4 | Early growth response protein 4 | Homo sapiens (Human) | PR |
| Q7Z398 | ZNF550 | Zinc finger protein 550 | Homo sapiens (Human) | PR |
| Q9Y2K1 | ZBTB1 | Zinc finger and BTB domain-containing protein 1 | Homo sapiens (Human) | PR |
| Q96N20 | ZNF75A | Zinc finger protein 75A | Homo sapiens (Human) | PR |
| A1YPR0 | ZBTB7C | Zinc finger and BTB domain-containing protein 7C | Homo sapiens (Human) | PR |
| P24278 | ZBTB25 | Zinc finger and BTB domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q96N38 | ZNF714 | Zinc finger protein 714 | Homo sapiens (Human) | PR |
| Q86YH2 | ZNF280B | Zinc finger protein 280B | Homo sapiens (Human) | PR |
| Q8NAM6 | ZSCAN4 | Zinc finger and SCAN domain-containing protein 4 | Homo sapiens (Human) | PR |
| Q9NPC7 | MYNN | Myoneurin | Homo sapiens (Human) | PR |
| O14978 | ZNF263 | Zinc finger protein 263 | Homo sapiens (Human) | PR |
| P17022 | ZNF18 | Zinc finger protein 18 | Homo sapiens (Human) | PR |
| Q6P9G9 | ZNF449 | Zinc finger protein 449 | Homo sapiens (Human) | PR |
| O60304 | ZNF500 | Zinc finger protein 500 | Homo sapiens (Human) | PR |
| Q9NX65 | ZSCAN32 | Zinc finger and SCAN domain-containing protein 32 | Homo sapiens (Human) | PR |
| Q96IT1 | ZNF496 | Zinc finger protein 496 | Homo sapiens (Human) | PR |
| O14771 | ZNF213 | Zinc finger protein 213 | Homo sapiens (Human) | PR |
| O95125 | ZNF202 | Zinc finger protein 202 | Homo sapiens (Human) | PR |
| Q8IWY8 | ZSCAN29 | Zinc finger and SCAN domain-containing protein 29 | Homo sapiens (Human) | PR |
| Q8N0Y2 | ZNF444 | Zinc finger protein 444 | Homo sapiens (Human) | PR |
| A6NGD5 | ZSCAN5C | Zinc finger and SCAN domain-containing protein 5C | Homo sapiens (Human) | PR |
| A6NJL1 | ZSCAN5B | Zinc finger and SCAN domain-containing protein 5B | Homo sapiens (Human) | PR |
| Q8NF99 | ZNF397 | Zinc finger protein 397 | Homo sapiens (Human) | PR |
| Q86XF7 | ZNF575 | Zinc finger protein 575 | Homo sapiens (Human) | PR |
| Q9NWS9 | ZNF446 | Zinc finger protein 446 | Homo sapiens (Human) | PR |
| Q96N95 | ZNF396 | Zinc finger protein 396 | Homo sapiens (Human) | PR |
| Q9UL58 | ZNF215 | Zinc finger protein 215 | Homo sapiens (Human) | PR |
| P17029 | ZKSCAN1 | Zinc finger protein with KRAB and SCAN domains 1 | Homo sapiens (Human) | PR |
| Q53GI3 | ZNF394 | Zinc finger protein 394 | Homo sapiens (Human) | PR |
| Q9BRR0 | ZKSCAN3 | Zinc finger protein with KRAB and SCAN domains 3 | Homo sapiens (Human) | PR |
| Q969J2 | ZKSCAN4 | Zinc finger protein with KRAB and SCAN domains 4 | Homo sapiens (Human) | PR |
| Q6NSZ9 | ZSCAN25 | Zinc finger and SCAN domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q9UNY5 | ZNF232 | Zinc finger protein 232 | Homo sapiens (Human) | PR |
| Q63HK3 | ZKSCAN2 | Zinc finger protein with KRAB and SCAN domains 2 | Homo sapiens (Human) | PR |
| P49910 | ZNF165 | Zinc finger protein 165 | Homo sapiens (Human) | PR |
| Q15776 | ZKSCAN8 | Zinc finger protein with KRAB and SCAN domains 8 | Homo sapiens (Human) | PR |
| Q9H9D4 | ZNF408 | Zinc finger protein 408 | Homo sapiens (Human) | PR |
| O08584 | Klf6 | Krueppel-like factor 6 | Mus musculus (Mouse) | PR |
| Q61164 | Ctcf | Transcriptional repressor CTCF | Mus musculus (Mouse) | PR |
| Q810A1 | Znf18 | Zinc finger protein 18 | Mus musculus (Mouse) | PR |
| Q8BGS3 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Mus musculus (Mouse) | PR |
| Q00899 | Yy1 | Transcriptional repressor protein YY1 | Mus musculus (Mouse) | PR |
| P41183 | Bcl6 | B-cell lymphoma 6 protein homolog | Mus musculus (Mouse) | PR |
| Q9DAI4 | Zbtb43 | Zinc finger and BTB domain-containing protein 43 | Mus musculus (Mouse) | PR |
| O70237 | Gfi1b | Zinc finger protein Gfi-1b | Mus musculus (Mouse) | PR |
| Q99KZ6 | Znf639 | Zinc finger protein 639 | Mus musculus (Mouse) | PR |
| Q9CXE0 | Prdm5 | PR domain zinc finger protein 5 | Mus musculus (Mouse) | PR |
| P43300 | Egr3 | Early growth response protein 3 | Mus musculus (Mouse) | PR |
| Q9DAU9 | Znf654 | Zinc finger protein 654 | Mus musculus (Mouse) | PR |
| Q9R1Y5 | Hic1 | Hypermethylated in cancer 1 protein | Mus musculus (Mouse) | PR |
| Q8R0T2 | Znf768 | Zinc finger protein 768 | Mus musculus (Mouse) | PR |
| Q9WVG7 | Osr1 | Protein odd-skipped-related 1 | Mus musculus (Mouse) | PR |
| Q8BI73 | Znf775 | Zinc finger protein 775 | Mus musculus (Mouse) | PR |
| Q8VCZ7 | Zbtb7c | Zinc finger and BTB domain-containing protein 7C | Mus musculus (Mouse) | PR |
| Q9DB38 | Znf580 | Zinc finger protein 580 | Mus musculus (Mouse) | PR |
| A7KBS4 | Zscan4d | Zinc finger and SCAN domain containing protein 4D | Mus musculus (Mouse) | PR |
| Q91VW9 | Zkscan3 | Zinc finger protein with KRAB and SCAN domains 3 | Mus musculus (Mouse) | PR |
| P10925 | Zfy1 | Zinc finger Y-chromosomal protein 1 | Mus musculus (Mouse) | PR |
| P08046 | Egr1 | Early growth response protein 1 | Mus musculus (Mouse) | PR |
| Q3TTC2 | Yy2 | Transcription factor YY2 | Mus musculus (Mouse) | PR |
| Q3UTQ7 | Prdm10 | PR domain zinc finger protein 10 | Mus musculus (Mouse) | PR |
| Q6P3Y5 | Znf280c | Zinc finger protein 280C | Mus musculus (Mouse) | PR |
| Q9ERU3 | Znf22 | Zinc finger protein 22 | Mus musculus (Mouse) | PR |
| Q8VIG1 | Rest | RE1-silencing transcription factor | Mus musculus (Mouse) | PR |
| Q9Z1D8 | Zkscan5 | Zinc finger protein with KRAB and SCAN domains 5 | Mus musculus (Mouse) | PR |
| Q8BID6 | Zbtb46 | Zinc finger and BTB domain-containing protein 46 | Mus musculus (Mouse) | PR |
| P17012 | Zfx | Zinc finger X-chromosomal protein | Mus musculus (Mouse) | PR |
| Q9WUK6 | Zbtb18 | Zinc finger and BTB domain-containing protein 18 | Mus musculus (Mouse) | PR |
| O35738 | Klf12 | Krueppel-like factor 12 | Mus musculus (Mouse) | PR |
| B2RXC5 | Znf382 | Zinc finger protein 382 | Mus musculus (Mouse) | PR |
| O08900 | Ikzf3 | Zinc finger protein Aiolos | Mus musculus (Mouse) | PR |
| Q5DU09 | Znf652 | Zinc finger protein 652 | Mus musculus (Mouse) | PR |
| Q8BLM0 | Klf8 | Krueppel-like factor 8 | Mus musculus (Mouse) | PR |
| Q99JB0 | Klf7 | Krueppel-like factor 7 | Mus musculus (Mouse) | PR |
| Q8R0A2 | Zbtb44 | Zinc finger and BTB domain-containing protein 44 | Mus musculus (Mouse) | PR |
| P20662 | Zfy2 | Zinc finger Y-chromosomal protein 2 | Mus musculus (Mouse) | PR |
| Q80VJ6 | Zscan4c | Zinc finger and SCAN domain containing protein 4C | Mus musculus (Mouse) | PR |
| Q3URS2 | Zscan4f | Zinc finger and SCAN domain containing protein 4F | Mus musculus (Mouse) | PR |
| Q60980 | Klf3 | Krueppel-like factor 3 | Mus musculus (Mouse) | PR |
| Q8K3J5 | Znf131 | Zinc finger protein 131 | Mus musculus (Mouse) | PR |
| Q5RJ54 | Zscan26 | Zinc finger and SCAN domain-containing protein 26 | Mus musculus (Mouse) | PR |
| Q9Z1D9 | Znf394 | Zinc finger protein 394 | Mus musculus (Mouse) | PR |
| Q91VN1 | Znf24 | Zinc finger protein 24 | Mus musculus (Mouse) | PR |
| Q9Z2K3 | Znf394 | Zinc finger protein 394 | Rattus norvegicus (Rat) | PR |
| Q642B9 | Znf18 | Zinc finger protein 18 | Rattus norvegicus (Rat) | PR |
| B0K011 | Osr1 | Protein odd-skipped-related 1 | Rattus norvegicus (Rat) | PR |
| D3ZUU2 | Gzf1 | GDNF-inducible zinc finger protein 1 | Rattus norvegicus (Rat) | PR |
| B1WBU4 | Zbtb8a | Zinc finger and BTB domain-containing protein 8A | Rattus norvegicus (Rat) | PR |
| O35819 | Klf6 | Krueppel-like factor 6 | Rattus norvegicus (Rat) | PR |
| Q9R1D1 | Ctcf | Transcriptional repressor CTCF | Rattus norvegicus (Rat) | PR |
| P43301 | Egr3 | Early growth response protein 3 | Rattus norvegicus (Rat) | PR |
| P08154 | Egr1 | Early growth response protein 1 | Rattus norvegicus (Rat) | PR |
| A0JPL0 | Znf382 | Zinc finger protein 382 | Rattus norvegicus (Rat) | PR |
| Q4KLI1 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Rattus norvegicus (Rat) | PR |
| A1L1J6 | Znf652 | Zinc finger protein 652 | Rattus norvegicus (Rat) | PR |
| Q7TNK3 | Znf24 | Zinc finger protein 24 | Rattus norvegicus (Rat) | PR |
| Q9SHD0 | ZAT4 | Zinc finger protein ZAT4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0P4X6 | zbtb44 | Zinc finger and BTB domain-containing protein 44 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| A4II20 | egr1 | Early growth response protein 1 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q6P882 | zbtb8a.2 | Zinc finger and BTB domain-containing protein 8A.2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q567C6 | znf367 | Zinc finger protein 367 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| A7Y7X5 | znf711 | Zinc finger protein 711 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAQSVEEDS | ILIIPTPDEE | EKILRVKLEE | DPDGEEGSSI | PWNHLPDPEI | FRQRFRQFGY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QDSPGPREAV | SQLRELCRLW | LRPETHTKEQ | ILELVVLEQF | VAILPKELQT | WVRDHHPENG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEAVTVLEDL | ESELDDPGQP | VSLRRRKREV | LVEDMVSQEE | AQGLPSSELD | AVENQLKWAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WELHSLRHCD | DDGRTENGAL | APKQELPSAL | ESHEVPGTLN | MGVPQIFKYG | ETCFPKGRFE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RKRNPSRKKQ | HICDECGKHF | SQGSALILHQ | RIHSGEKPYG | CVECGKAFSR | SSILVQHQRV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HTGEKPYKCL | ECGKAFSQNS | GLINHQRIHT | GEKPYECVQC | GKSYSQSSNL | FRHQRRHNAE |
| KLLNVVKV |