Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P17022

Entry ID Method Resolution Chain Position Source
AF-P17022-F1 Predicted AlphaFoldDB

425 variants for P17022

Variant ID(s) Position Change Description Diseaes Association Provenance
CA288003128
rs751280866
2 P>L No ClinGen
Ensembl
rs377302753
CA8398821
COSM1665135
2 P>S kidney [Cosmic] No ClinGen
cosmic curated
ESP
ExAC
TOPMed
gnomAD
rs377302753
CA8398820
2 P>T No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs777495225
CA8398818
3 V>I No ClinGen
ExAC
TOPMed
gnomAD
rs1567607998
CA398212798
4 D>E No ClinGen
Ensembl
CA8398817
rs755941701
4 D>G No ClinGen
ExAC
TOPMed
gnomAD
rs1438395906
CA398212785
6 G>E No ClinGen
TOPMed
gnomAD
CA398212782
rs1250407092
7 Q>* No ClinGen
gnomAD
rs1463075317
CA398212774
8 A>S No ClinGen
TOPMed
CA8398814
rs755065533
11 L>P No ClinGen
ExAC
gnomAD
rs1014098596
CA288003073
13 P>L No ClinGen
TOPMed
gnomAD
CA8398812
rs142427652
COSM1271056
14 S>L oesophagus [Cosmic] No ClinGen
cosmic curated
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA398212732
rs750799096
16 A>G No ClinGen
ExAC
TOPMed
gnomAD
CA288003063
rs868471262
16 A>T No ClinGen
Ensembl
CA8398810
rs750799096
16 A>V No ClinGen
ExAC
TOPMed
gnomAD
rs765457977
CA8398809
17 K>N No ClinGen
ExAC
gnomAD
rs762252095
CA8398808
18 A>T No ClinGen
ExAC
TOPMed
gnomAD
CA398212718
rs1377448549
19 E>K No ClinGen
TOPMed
gnomAD
rs1377448549
CA398212719
19 E>Q No ClinGen
TOPMed
gnomAD
rs759018357
CA8398805
CA288003052
22 Q>H No ClinGen
ExAC
TOPMed
gnomAD
CA8398803
rs770896124
24 S>* No ClinGen
ExAC
gnomAD
rs762731148
CA8398802
25 E>K No ClinGen
ExAC
TOPMed
gnomAD
rs763558349
CA288003041
26 S>P No ClinGen
gnomAD
CA8398801
rs773214642
27 D>G No ClinGen
ExAC
TOPMed
gnomAD
rs757525586
CA288003034
27 D>H No ClinGen
Ensembl
rs1567607802
CA398212656
28 A>D No ClinGen
Ensembl
CA288003003
rs866583589
30 L>F No ClinGen
Ensembl
rs1179341537
CA398212642
31 Q>E No ClinGen
gnomAD
CA398212640
rs1486381203
31 Q>P No ClinGen
gnomAD
TCGA novel 33 E>G Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398212608
rs1440390899
35 S>F No ClinGen
gnomAD
CA398212597
COSM704999
rs1225834251
37 P>S lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] No ClinGen
cosmic curated
NCI-TCGA
gnomAD
CA398212585
rs1288293520
39 T>P No ClinGen
gnomAD
CA398212578
rs769046477
40 A>S No ClinGen
ExAC
gnomAD
rs769046477
CA8398796
40 A>T Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
rs747075784
CA8398795
41 R>C No ClinGen
ExAC
TOPMed
gnomAD
CA8398794
rs539768789
COSM975553
41 R>H Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
1000Genomes
ExAC
NCI-TCGA
TOPMed
gnomAD
rs1357659783
CA398212560
43 L>F No ClinGen
gnomAD
rs758513999
CA8398792
48 R>C Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
CA8398791
rs141331318
48 R>H No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
TCGA novel 49 Y>* Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs11545759
CA288002913
50 Q>* No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs11545759
CA8398790
50 Q>E No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1476172125
CA398212510
50 Q>R No ClinGen
TOPMed
gnomAD
CA398212504
rs1567607661
51 V>A No ClinGen
Ensembl
CA8398789
rs757579809
51 V>M No ClinGen
ExAC
gnomAD
CA398212496
rs767141001
CA8398787
52 M>I No ClinGen
ExAC
TOPMed
gnomAD
CA8398786
rs759250037
53 S>P No ClinGen
ExAC
gnomAD
CA8398785
rs751216201
54 G>E No ClinGen
ExAC
gnomAD
TCGA novel 54 G>V Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs188440121
CA288002870
56 H>Q No ClinGen
1000Genomes
rs765748832
CA8398784
59 L>M No ClinGen
ExAC
TOPMed
TCGA novel 62 L>I Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398212429
rs183777667
63 R>G No ClinGen
1000Genomes
ExAC
gnomAD
CA8398782
rs772979075
COSM1493774
63 R>Q kidney Variant assessed as Somatic; 4.619e-05 impact. [Cosmic, NCI-TCGA] No ClinGen
cosmic curated
ExAC
NCI-TCGA
TOPMed
gnomAD
CA8398783
rs183777667
63 R>W Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
1000Genomes
ExAC
NCI-TCGA
gnomAD
CA398212418
rs1207383462
65 L>F No ClinGen
gnomAD
rs145411425
CA8398780
67 F>L No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs761675373
CA8398779
68 Q>* No ClinGen
ExAC
gnomAD
rs776627793
CA8398778
69 W>* No ClinGen
ExAC
gnomAD
CA8398775
rs780337356
71 Q>K No ClinGen
ExAC
gnomAD
CA398212374
rs1318376546
71 Q>R No ClinGen
gnomAD
rs1399473639
CA398212367
72 P>Q No ClinGen
TOPMed
rs566715139
CA288002772
73 E>D No ClinGen
gnomAD
CA398212355
rs1597976594
74 V>G No ClinGen
Ensembl
rs772001286
CA8398774
74 V>I No ClinGen
ExAC
gnomAD
rs200065032
CA8398773
75 H>P No ClinGen
ExAC
gnomAD
rs200065032
CA288002743
75 H>R No ClinGen
ExAC
gnomAD
rs1330341875
CA398212341
76 T>S No ClinGen
TOPMed
rs1186712196
CA398212333
77 K>N No ClinGen
gnomAD
rs1448569711
CA398212310
80 I>M No ClinGen
gnomAD
CA398212298
rs1435284670
82 E>D No ClinGen
TOPMed
CA288002721
rs200136196
87 E>* No ClinGen
1000Genomes
TOPMed
CA288002729
rs200136196
87 E>K No ClinGen
1000Genomes
TOPMed
CA398212253
rs1247785886
89 F>I No ClinGen
gnomAD
CA8398771
rs757813028
94 P>R No ClinGen
ExAC
gnomAD
TCGA novel 95 G>R Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398212198
rs1597976457
97 I>S No ClinGen
Ensembl
rs778041681
CA8398769
98 Q>E No ClinGen
ExAC
gnomAD
CA8398768
rs756480819
100 W>* No ClinGen
ExAC
gnomAD
CA398212179
rs1220871124
100 W>R No ClinGen
gnomAD
CA288002705
rs1023330883
102 R>Q No ClinGen
TOPMed
rs375481169
CA8398767
102 R>W No ClinGen
ESP
ExAC
TOPMed
gnomAD
TCGA novel 103 K>N Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1364745395
CA398212129
107 G>E No ClinGen
TOPMed
gnomAD
CA8398766
rs766086638
108 S>N No ClinGen
ExAC
gnomAD
rs757814225
CA8398765
109 G>R No ClinGen
ExAC
gnomAD
rs749997258
CA8398764
112 A>S No ClinGen
ExAC
gnomAD
CA8398763
rs368958103
112 A>V No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA8398762
rs761910327
113 V>M No ClinGen
ExAC
gnomAD
rs1428642841
CA398212087
114 T>N No ClinGen
gnomAD
CA8398761
rs776715145
115 L>I No ClinGen
ExAC
TOPMed
gnomAD
rs1567607338
CA398212077
116 V>L No ClinGen
Ensembl
rs760568955
CA8398759
118 S>R No ClinGen
ExAC
gnomAD
rs775538342
CA8398758
120 K>Q No ClinGen
ExAC
TOPMed
gnomAD
rs1390814387
CA398212033
122 D>E Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
gnomAD
CA8398756
rs148878294
122 D>N No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA8398755
rs774554134
123 P>L No ClinGen
ExAC
gnomAD
rs1236827415
CA398212023
124 Q>* No ClinGen
gnomAD
CA288002600
rs1005018995
124 Q>R No ClinGen
Ensembl
CA398212011
rs1384994023
126 L>M No ClinGen
gnomAD
rs1475682224
CA398212008
126 L>P No ClinGen
TOPMed
CA398211999
rs1555536328
127 W>* No ClinGen
Ensembl
rs1410978404
CA398211985
129 W>* Variant assessed as Somatic; impact. [NCI-TCGA] No ClinGen
NCI-TCGA
TOPMed
rs1409831285
CA398211457
132 I>V No ClinGen
gnomAD
CA8398728
rs781667501
133 Q>H No ClinGen
ExAC
gnomAD
TCGA novel 134 V>A Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs894229710
CA288001544
139 I>T No ClinGen
TOPMed
CA398211352
rs1241602700
139 I>V No ClinGen
Ensembl
CA8398726
rs145623670
141 S>P No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA398211298
rs1466072260
143 K>N No ClinGen
gnomAD
CA398211294
rs1268574060
144 M>V No ClinGen
gnomAD
rs1281250761
CA398211272
145 E>A No ClinGen
TOPMed
rs377233844
CA288001534
145 E>D No ClinGen
ESP
TOPMed
CA8398724
rs139692409
147 P>L No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA398211253
rs1208028865
147 P>S No ClinGen
gnomAD
rs1294536568
CA398211228
149 C>F No ClinGen
TOPMed
gnomAD
CA398211215
rs1244918172
150 Q>L No ClinGen
gnomAD
rs1264441058
CA398211206
151 V>E No ClinGen
TOPMed
rs539118760
CA8398722
152 G>R No ClinGen
1000Genomes
ExAC
gnomAD
rs898427357
CA288001503
156 P>L No ClinGen
TOPMed
rs756138317
CA8398721
156 P>S No ClinGen
ExAC
gnomAD
rs756138317
CA398211157
156 P>T No ClinGen
ExAC
gnomAD
CA8398720
rs752579295
158 L>P No ClinGen
ExAC
TOPMed
gnomAD
rs1321710534
CA398211108
160 V>A No ClinGen
gnomAD
rs767281105
CA8398719
162 P>L No ClinGen
ExAC
gnomAD
rs894965154
CA288001466
163 Q>P No ClinGen
TOPMed
gnomAD
rs894965154
CA398211079
163 Q>R No ClinGen
TOPMed
gnomAD
CA398211057
rs759267603
165 L>M No ClinGen
ExAC
TOPMed
gnomAD
rs1458495225
CA398211042
166 G>E No ClinGen
gnomAD
rs751735962
CA8398717
169 N>S No ClinGen
ExAC
gnomAD
CA398211008
rs1387033946
171 S>Y No ClinGen
gnomAD
TCGA novel 172 S>L Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398210992
rs1597972536
174 P>A No ClinGen
Ensembl
rs773336393
CA8398715
176 E>D No ClinGen
ExAC
gnomAD
TCGA novel 176 E>S Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398712
rs762315625
179 S>N No ClinGen
ExAC
gnomAD
CA398210953
rs1291960645
180 H>L No ClinGen
gnomAD
CA8398711
rs769016734
181 I>F No ClinGen
ExAC
TOPMed
gnomAD
CA8398710
rs769016734
181 I>V No ClinGen
ExAC
TOPMed
gnomAD
CA8398706
rs748796960
182 V>A No ClinGen
ExAC
gnomAD
CA8398708
rs367643118
182 V>L No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA8398707
rs367643118
182 V>M Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ESP
ExAC
NCI-TCGA
TOPMed
gnomAD
rs777494329
CA8398704
188 T>A No ClinGen
ExAC
TOPMed
gnomAD
rs752628886
CA8398702
193 A>P No ClinGen
ExAC
gnomAD
rs747647673
CA8398685
194 L>P No ClinGen
ExAC
gnomAD
rs1597971413
CA398210842
196 A>P No ClinGen
Ensembl
TCGA novel 196 A>V Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1597971391
CA398210836
197 S>P No ClinGen
Ensembl
CA288000783
rs1054645173
198 Q>E No ClinGen
Ensembl
CA398210828
rs1321986101
198 Q>R No ClinGen
TOPMed
CA8398683
rs754927912
199 P>S No ClinGen
ExAC
gnomAD
CA398210812
rs1307615761
201 R>* No ClinGen
TOPMed
gnomAD
rs766128915
CA288000778
201 R>P No ClinGen
ExAC
TOPMed
gnomAD
rs766128915
CA8398682
201 R>Q No ClinGen
ExAC
TOPMed
gnomAD
TCGA novel 203 E>* Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1172958148
CA398210789
205 R>G No ClinGen
gnomAD
rs758205300
CA8398680
205 R>K No ClinGen
ExAC
gnomAD
rs750596606
CA8398679
205 R>S No ClinGen
ExAC
TOPMed
gnomAD
rs368785851
CA288000763
206 L>M No ClinGen
gnomAD
rs924804240
CA288000756
206 L>P No ClinGen
Ensembl
TCGA novel 207 I>T Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398678
rs765409540
209 D>H No ClinGen
ExAC
gnomAD
CA288000740
rs17857095
VAR_024835
210 Q>R No ClinGen
UniProt
Ensembl
dbSNP
rs1281081332
CA398210751
211 D>A No ClinGen
gnomAD
rs1597971134
CA398210747
211 D>E No ClinGen
Ensembl
rs753918138
CA8398676
211 D>N No ClinGen
ExAC
gnomAD
CA8398674
rs761333923
213 G>R No ClinGen
ExAC
TOPMed
gnomAD
CA288000677
rs991859324
219 A>T No ClinGen
Ensembl
CA398210702
rs1415742903
219 A>V No ClinGen
TOPMed
CA8398671
rs767941184
222 Q>* No ClinGen
ExAC
gnomAD
rs775375665
CA8398636
223 E>K No ClinGen
ExAC
gnomAD
rs867017621
CA287995741
224 Q>K No ClinGen
gnomAD
rs766946917
CA287995737
224 Q>P No ClinGen
Ensembl
CA398209764
rs1190926461
225 W>G No ClinGen
gnomAD
rs1465707100
CA398209746
226 R>K No ClinGen
gnomAD
CA398209718
rs937089881
228 L>V No ClinGen
TOPMed
gnomAD
CA398209688
rs1331060890
230 S>Y No ClinGen
TOPMed
rs1323559259
CA398209681
231 T>A No ClinGen
gnomAD
TCGA novel 233 K>N Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA287995698
rs147883752
238 D>E No ClinGen
ESP
TOPMed
gnomAD
CA287995697
rs763461287
239 L>I No ClinGen
TOPMed
gnomAD
CA287995694
VAR_024836
rs17853545
240 M>I No ClinGen
UniProt
Ensembl
dbSNP
TCGA novel 242 E>D Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398209435
rs749416733
244 Y>C No ClinGen
ExAC
gnomAD
CA8398631
rs749416733
244 Y>F No ClinGen
ExAC
gnomAD
rs778169714
COSM472311
CA8398630
248 V>A kidney [Cosmic] No ClinGen
cosmic curated
ExAC
TOPMed
gnomAD
CA8398629
rs756229785
250 G>E No ClinGen
ExAC
TOPMed
gnomAD
rs1187111223
CA398209195
253 I>V No ClinGen
gnomAD
CA398209173
rs1431086290
254 S>Y No ClinGen
TOPMed
CA398209145
rs1312663563
256 P>L No ClinGen
TOPMed
gnomAD
CA398209119
rs1377490918
258 S>Y No ClinGen
TOPMed
rs1422010556
CA398209093
260 L>P No ClinGen
gnomAD
CA8398602
rs200385412
261 T>I No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs200385412
CA8398603
261 T>N No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs760390082
CA8398601
263 S>L No ClinGen
ExAC
gnomAD
rs766958799
CA8398599
264 I>M No ClinGen
ExAC
gnomAD
rs144636825
CA287994992
264 I>T No ClinGen
ESP
TOPMed
gnomAD
CA8398600
rs376315353
264 I>V No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
TCGA novel 266 F>C Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 267 G>R Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398597
rs759111070
268 E>D No ClinGen
ExAC
gnomAD
TCGA novel 269 E>* Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398596
rs774122043
269 E>K No ClinGen
ExAC
gnomAD
rs1183007542
CA398208961
272 G>E No ClinGen
gnomAD
rs541839883
CA287994981
272 G>R No ClinGen
1000Genomes
gnomAD
rs77956991
CA8398593
273 I>L No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs77956991
CA8398594
273 I>V No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA8398592
rs769714964
274 Y>H No ClinGen
ExAC
gnomAD
CA287994933
rs759049128
276 H>Q No ClinGen
ExAC
gnomAD
rs1201685600
CA398208936
276 H>R No ClinGen
gnomAD
rs1024519928
CA287994930
277 V>D No ClinGen
Ensembl
CA8398588
rs147695825
278 N>S No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1313448079
CA398208918
279 E>A No ClinGen
TOPMed
gnomAD
CA398208919
rs1333579307
279 E>K No ClinGen
gnomAD
TCGA novel 280 K>R Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398587
rs747154566
284 P>A No ClinGen
ExAC
gnomAD
CA398208883
rs200854003
284 P>H No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs200854003
CA8398586
284 P>L No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs1156291116
CA398208874
286 C>R No ClinGen
TOPMed
CA398208871
rs1380328833
286 C>S No ClinGen
gnomAD
CA398208872
rs1380328833
286 C>Y No ClinGen
gnomAD
CA287994889
rs967481078
287 I>T No ClinGen
TOPMed
rs765073785
CA8398573
289 D>H No ClinGen
ExAC
gnomAD
TCGA novel 289 D>N Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 290 R>G Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs546049246
CA8398571
290 R>I No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs1382214710
CA398207988
290 R>S No ClinGen
gnomAD
rs546049246
CA8398570
290 R>T No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
rs762146492
CA8398569
291 Q>* No ClinGen
ExAC
gnomAD
CA8398566
rs775707316
303 H>Q No ClinGen
ExAC
gnomAD
TCGA novel 303 H>T Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
TCGA novel 306 Q>missing Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398565
rs142899087
308 L>P No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1451060743
CA398207843
310 H>P No ClinGen
gnomAD
TCGA novel 314 Q>R Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA287991798
rs920870027
315 A>T No ClinGen
TOPMed
rs746318739
CA8398564
315 A>V No ClinGen
ExAC
gnomAD
CA398207797
rs1251790472
317 G>E No ClinGen
TOPMed
COSM3736152
rs779423242
CA8398563
318 E>K skin [Cosmic] No ClinGen
cosmic curated
ExAC
TOPMed
gnomAD
rs1445276240
CA398207787
319 V>F No ClinGen
gnomAD
CA8398562
rs148571831
321 S>F No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA398207766
rs1245705887
322 Q>* No ClinGen
gnomAD
CA8398561
rs749698025
323 A>S No ClinGen
ExAC
gnomAD
CA8398560
rs780690654
323 A>V No ClinGen
ExAC
TOPMed
gnomAD
rs754723749
CA8398559
325 L>S No ClinGen
ExAC
gnomAD
rs910727191
CA287991781
325 L>V No ClinGen
TOPMed
COSM1380914
rs765856443
CA8398557
328 F>V Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] No ClinGen
cosmic curated
ExAC
NCI-TCGA
gnomAD
rs1227255180
CA398207642
331 E>G No ClinGen
gnomAD
rs1272903645
CA398207634
332 D>N No ClinGen
gnomAD
CA398207602
rs1567596854
333 E>D No ClinGen
Ensembl
CA398207614
rs1194393554
333 E>K No ClinGen
TOPMed
rs1325552027
CA398207586
335 G>R No ClinGen
gnomAD
rs1046673073
CA287991766
337 F>S No ClinGen
TOPMed
TCGA novel 337 F>V Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398207514
rs1208438922
340 G>R No ClinGen
gnomAD
rs1395239392
CA398207484
341 E>D No ClinGen
TOPMed
rs1164843217
CA398207498
341 E>Q No ClinGen
TOPMed
CA8398553
rs750346148
343 L>F No ClinGen
ExAC
gnomAD
rs1463135715
CA398207436
344 P>L No ClinGen
TOPMed
CA8398552
rs765304834
344 P>S No ClinGen
ExAC
gnomAD
CA287991741
rs916794282
345 E>D No ClinGen
Ensembl
CA8398551
rs761679323
347 L>P No ClinGen
ExAC
TOPMed
gnomAD
rs973982524
CA287991731
347 L>V No ClinGen
Ensembl
rs372507981
CA8398550
348 Q>E No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs764220391
CA8398549
349 N>S No ClinGen
ExAC
gnomAD
CA398207349
rs1266224375
351 Q>* No ClinGen
gnomAD
rs1295963347
CA398207342
351 Q>H No ClinGen
TOPMed
rs1342173715
CA398207334
352 D>N No ClinGen
TOPMed
rs760886148
CA8398548
353 E>* No ClinGen
ExAC
gnomAD
CA8398546
rs772144825
354 G>E No ClinGen
ExAC
TOPMed
gnomAD
rs772144825
CA398207294
354 G>V No ClinGen
ExAC
TOPMed
gnomAD
CA287991677
rs968594765
357 E>K No ClinGen
TOPMed
gnomAD
CA398207249
rs369183624
358 Q>* No ClinGen
ESP
TOPMed
gnomAD
CA287991675
rs369183624
358 Q>K No ClinGen
ESP
TOPMed
gnomAD
rs759647910
CA8398544
358 Q>R No ClinGen
ExAC
gnomAD
rs1281525184
CA398207217
360 S>F No ClinGen
gnomAD
CA8398543
rs774812837
360 S>P No ClinGen
ExAC
gnomAD
TCGA novel 362 Q>E Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs771481859
CA8398542
362 Q>H No ClinGen
ExAC
gnomAD
rs1407974313
CA398207158
365 I>T No ClinGen
gnomAD
CA398207150
rs1258549648
366 S>F No ClinGen
TOPMed
CA8398540
rs376345871
368 K>E No ClinGen
ESP
ExAC
gnomAD
rs1183735351
CA398207095
374 L>* No ClinGen
gnomAD
CA8398536
rs201272840
374 L>F No ClinGen
1000Genomes
ExAC
gnomAD
CA398207089
rs1179271271
375 P>L No ClinGen
TOPMed
gnomAD
CA8398535
rs757950387
375 P>S No ClinGen
ExAC
gnomAD
CA398207083
rs1281234210
376 N>T No ClinGen
gnomAD
CA398207086
rs1436409811
376 N>Y No ClinGen
gnomAD
rs1204856522
CA398207075
377 P>L No ClinGen
TOPMed
gnomAD
CA8398534
rs191353566
378 H>N No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
rs778981241
CA8398533
378 H>R No ClinGen
ExAC
gnomAD
CA8398532
rs140193484
380 G>E No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs866414386
CA287991604
380 G>K No ClinGen
Ensembl
CA398207044
rs1597941439
382 M>I No ClinGen
Ensembl
CA8398531
rs753725476
382 M>T No ClinGen
ExAC
gnomAD
rs1279170227
CA398207048
382 M>V No ClinGen
gnomAD
rs1342038559
CA398207038
383 S>C No ClinGen
gnomAD
rs1363319366
CA398207030
384 T>I No ClinGen
TOPMed
TCGA novel 386 W>* Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1451757354
COSM40782
CA398207011
387 L>F central_nervous_system [Cosmic] No ClinGen
cosmic curated
gnomAD
CA398207003
rs1597941384
388 E>* No ClinGen
Ensembl
rs1160685182
CA398206991
389 E>D No ClinGen
gnomAD
TCGA novel 389 E>missing Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398206992
rs1597941358
389 E>G No ClinGen
Ensembl
rs1403844921
CA398206997
389 E>K No ClinGen
gnomAD
rs763210939
CA8398529
390 K>R No ClinGen
ExAC
TOPMed
gnomAD
rs199778478
CA8398528
391 R>T No ClinGen
1000Genomes
ExAC
gnomAD
CA398206976
rs1290858202
392 E>K No ClinGen
TOPMed
CA398206966
rs1597941269
393 T>P No ClinGen
Ensembl
rs759595081
CA8398524
394 S>F No ClinGen
ExAC
gnomAD
CA398206961
rs1597941244
394 S>P No ClinGen
Ensembl
rs771001322
CA8398522
395 Q>H No ClinGen
ExAC
gnomAD
CA398206956
rs1597941220
395 Q>K No ClinGen
Ensembl
CA8398521
rs763389765
396 K>R No ClinGen
ExAC
gnomAD
CA8398519
rs770154003
399 P>S No ClinGen
ExAC
gnomAD
rs867646621
CA287991482
402 P>L No ClinGen
Ensembl
rs748501914
CA8398518
402 P>S No ClinGen
ExAC
rs1283735843
CA398206906
403 M>V No ClinGen
gnomAD
rs1229515359
CA398206878
406 K>N No ClinGen
TOPMed
rs1304184948
CA398206874
407 L>F No ClinGen
TOPMed
CA8398517
rs771910345
408 P>S No ClinGen
ExAC
gnomAD
CA8398516
rs771910345
408 P>T No ClinGen
ExAC
gnomAD
rs375117406
CA8398514
412 E>* No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs753763399
CA8398513
413 C>F No ClinGen
ExAC
TOPMed
gnomAD
rs566420474
CA287991433
413 C>R No ClinGen
1000Genomes
rs753763399
CA8398512
413 C>Y No ClinGen
ExAC
TOPMed
gnomAD
rs1344084565
CA398206822
CA398206821
415 K>N No ClinGen
TOPMed
gnomAD
rs777605567
CA8398511
415 K>R No ClinGen
ExAC
gnomAD
rs1406680832
CA398206801
418 Y>F No ClinGen
gnomAD
rs752487480
CA8398509
421 S>C No ClinGen
ExAC
gnomAD
CA287991393
rs200567412
421 S>P No ClinGen
1000Genomes
gnomAD
rs767719136
CA8398508
423 L>F No ClinGen
ExAC
TOPMed
gnomAD
CA8398507
rs755121788
423 L>H No ClinGen
ExAC
gnomAD
CA8398506
rs142362324
425 F>C No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
CA8398504
rs762973080
426 H>Q No ClinGen
ExAC
gnomAD
CA8398505
rs137912942
426 H>Y No ClinGen
ESP
ExAC
gnomAD
CA8398503
rs773738207
428 R>K No ClinGen
ExAC
gnomAD
CA398206729
rs765712023
429 T>I No ClinGen
ExAC
gnomAD
rs765712023
CA8398502
429 T>S No ClinGen
ExAC
gnomAD
CA287991346
rs201689807
430 H>N No ClinGen
1000Genomes
CA8398500
rs777203770
432 G>R Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
CA398206696
rs1361197013
435 Y>H No ClinGen
gnomAD
rs774172225
CA8398497
437 Q>E No ClinGen
ExAC
TOPMed
gnomAD
rs141254598
CA8398496
438 C>Y No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs910685452
CA287991305
439 T>I No ClinGen
TOPMed
rs756069184
CA8398494
440 I>N No ClinGen
ExAC
TOPMed
gnomAD
CA8398493
rs756069184
440 I>T No ClinGen
ExAC
TOPMed
gnomAD
CA8398495
rs748792574
440 I>V No ClinGen
ExAC
gnomAD
rs1371966400
CA398206645
442 K>R No ClinGen
TOPMed
CA8398492
rs550778787
443 K>T No ClinGen
1000Genomes
ExAC
gnomAD
CA8398491
rs766643102
444 A>V No ClinGen
ExAC
gnomAD
rs751739674
CA8398489
445 F>S No ClinGen
ExAC
gnomAD
rs529430089
CA398206617
447 R>G No ClinGen
1000Genomes
ExAC
TOPMed
gnomAD
CA398206616
rs1479035271
447 R>Q No ClinGen
gnomAD
rs529430089
CA8398488
447 R>W Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
1000Genomes
ExAC
NCI-TCGA
TOPMed
gnomAD
rs1597940614
CA398206600
449 S>L No ClinGen
Ensembl
rs1269763481
CA398206573
453 K>R No ClinGen
gnomAD
rs1345361762
CA398206560
455 Q>E No ClinGen
TOPMed
rs933067074
CA287991281
456 R>K No ClinGen
TOPMed
CA398206541
rs750526470
457 T>I No ClinGen
ExAC
gnomAD
rs1281439413
CA398206545
457 T>P No ClinGen
TOPMed
CA8398486
rs750526470
457 T>S No ClinGen
ExAC
gnomAD
CA398206531
rs1276433540
459 T>A No ClinGen
gnomAD
rs762161028
CA8398485
459 T>K No ClinGen
ExAC
gnomAD
rs762161028
CA8398484
459 T>M Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
ExAC
NCI-TCGA
gnomAD
rs1270776199
CA398206523
460 G>V No ClinGen
gnomAD
CA8398482
rs764505697
461 E>K No ClinGen
ExAC
TOPMed
gnomAD
CA287991267
rs760852623
463 P>R No ClinGen
TOPMed
gnomAD
CA287991255
rs868652668
464 C>F No ClinGen
Ensembl
TCGA novel 465 K>T Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs150200103
CA8398480
467 D>G No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
TCGA novel 469 C>F Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs770543851
CA8398479
470 G>V No ClinGen
ExAC
gnomAD
CA398206409
rs1300223792
472 G>D No ClinGen
gnomAD
rs1196379467
CA398206396
473 F>S No ClinGen
gnomAD
rs772525995
CA8398477
475 D>E No ClinGen
ExAC
gnomAD
rs62621364
TCGA novel
CA8398476
COSM173978
476 F>L large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] No ClinGen
cosmic curated
1000Genomes
ESP
ExAC
TOPMed
gnomAD
NCI-TCGA
rs781135332
CA8398474
480 R>C No ClinGen
ExAC
TOPMed
gnomAD
CA398206306
rs1195710140
480 R>H Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No ClinGen
NCI-TCGA
gnomAD
CA8398472
rs147644785
483 E>K No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs758615355
CA8398470
484 K>N No ClinGen
ExAC
TOPMed
gnomAD
CA398206234
rs750664018
485 I>N No ClinGen
ExAC
gnomAD
rs750664018
CA8398469
485 I>T No ClinGen
ExAC
gnomAD
TCGA novel 488 G>E Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs757382699
CA8398467
491 P>L No ClinGen
ExAC
gnomAD
rs1324204506
CA398206133
493 K>Q No ClinGen
gnomAD
rs1221189360
CA398206073
497 C>Y No ClinGen
gnomAD
rs1353903199
CA398206053
498 E>D No ClinGen
TOPMed
CA8398466
rs754359351
499 K>R No ClinGen
ExAC
TOPMed
gnomAD
rs958906220
CA287991156
503 Q>R No ClinGen
TOPMed
gnomAD
CA8398465
rs142343519
505 S>P No ClinGen
ESP
ExAC
TOPMed
gnomAD
CA287991142
rs142343519
505 S>T No ClinGen
ESP
ExAC
TOPMed
gnomAD
rs1439615988
CA398205984
506 N>D No ClinGen
TOPMed
TCGA novel 509 R>I Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
rs1597939948
CA398205947
510 H>Q No ClinGen
Ensembl
CA398205941
rs1438920914
511 Q>P No ClinGen
TOPMed
gnomAD
CA398205916
rs1567595649
515 T>A No ClinGen
Ensembl
rs1370160581
CA398205914
515 T>I No ClinGen
TOPMed
CA398205907
rs1454990727
516 G>A No ClinGen
gnomAD
TCGA novel 517 E>D Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA398205867
rs1175748186
522 C>R No ClinGen
gnomAD
rs761826934
CA287991124
522 C>S No ClinGen
gnomAD
rs761826934
CA398205864
522 C>Y No ClinGen
gnomAD
rs762451481
CA8398461
523 S>A No ClinGen
ExAC
gnomAD
rs117755721
CA8398460
523 S>L No ClinGen
1000Genomes
ESP
ExAC
TOPMed
gnomAD
TCGA novel 524 H>Q Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398458
rs761350849
524 H>Y No ClinGen
ExAC
gnomAD
CA8398457
rs776526017
525 C>R No ClinGen
ExAC
gnomAD
TCGA novel 528 S>F Variant assessed as Somatic; impact. [NCI-TCGA] No NCI-TCGA
CA8398454
rs746802858
530 S>R No ClinGen
ExAC
CA8398452
rs779647891
530 S>R No ClinGen
ExAC
CA8398450
rs771915904
533 S>L No ClinGen
ExAC
TOPMed
gnomAD
CA398205785
rs771915904
533 S>W No ClinGen
ExAC
TOPMed
gnomAD
rs1468102494
CA398205758
537 K>R No ClinGen
TOPMed
rs970467985
CA287991086
538 H>Y No ClinGen
Ensembl
CA398205743
rs1305241881
539 Q>R No ClinGen
gnomAD
rs1248661439
CA398205737
540 R>K No ClinGen
gnomAD
CA398205707
rs1336639959
544 G>A No ClinGen
gnomAD
CA8398444
rs778414929
547 P>R No ClinGen
ExAC
gnomAD
rs993597941
CA287991077
548 F>I No ClinGen
TOPMed
CA8398443
rs756755439
549 Q>E No ClinGen
ExAC
gnomAD
rs1012339053 550 Q>= Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] No NCI-TCGA
CA398205668
rs1567595411
550 Q>E No ClinGen
Ensembl
CA287991060
rs1012339053
550 Q>Y No ClinGen
gnomAD

No associated diseases with P17022

7 regional properties for P17022

Type Name Position InterPro Accession
domain Krueppel-associated box 211 - 283 IPR001909
domain SCAN domain 37 - 149 IPR003309
domain Zinc finger C2H2-type 408 - 435 IPR013087-1
domain Zinc finger C2H2-type 436 - 463 IPR013087-2
domain Zinc finger C2H2-type 464 - 491 IPR013087-3
domain Zinc finger C2H2-type 492 - 519 IPR013087-4
domain Zinc finger C2H2-type 520 - 547 IPR013087-5

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
metal ion binding Binding to a metal ion.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

1 GO annotations of biological process

Name Definition
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

177 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q08DS3 OSR1 Protein odd-skipped-related 1 Bos taurus (Bovine) PR
Q2VWH6 FEZF2 Fez family zinc finger protein 2 Bos taurus (Bovine) PR
A6QNZ0 ZSCAN26 Zinc finger and SCAN domain-containing protein 26 Bos taurus (Bovine) PR
A7MBI1 ZFP69 Zinc finger protein 69 homolog Bos taurus (Bovine) PR
Q08705 CTCF Transcriptional repressor CTCF Gallus gallus (Chicken) PR
O42409 GFI1B Zinc finger protein Gfi-1b Gallus gallus (Chicken) PR
A2T6W2 ZNF449 Zinc finger protein 449 Pan troglodytes (Chimpanzee) PR
Q9U405 grau Transcription factor grauzone Drosophila melanogaster (Fruit fly) PR
Q7K0S9 sug Zinc finger protein GLIS2 homolog Drosophila melanogaster (Fruit fly) PR
P20385 Cf2 Chorion transcription factor Cf2 Drosophila melanogaster (Fruit fly) PR
Q86P48 ATbp AT-rich binding protein Drosophila melanogaster (Fruit fly) PR
P28698 MZF1 Myeloid zinc finger 1 Homo sapiens (Human) PR
Q9NTW7 ZFP64 Zinc finger protein 64 Homo sapiens (Human) PR
P08151 GLI1 Zinc finger protein GLI1 Homo sapiens (Human) PR
Q9UFB7 ZBTB47 Zinc finger and BTB domain-containing protein 47 Homo sapiens (Human) PR
P18146 EGR1 Early growth response protein 1 Homo sapiens (Human) PR
Q9Y5W3 KLF2 Krueppel-like factor 2 Homo sapiens (Human) PR
Q96SZ4 ZSCAN10 Zinc finger and SCAN domain-containing protein 10 Homo sapiens (Human) PR
P57682 KLF3 Krueppel-like factor 3 Homo sapiens (Human) PR
P25490 YY1 Transcriptional repressor protein YY1 Homo sapiens (Human) SS
O43296 ZNF264 Zinc finger protein 264 Homo sapiens (Human) PR
P49711 CTCF Transcriptional repressor CTCF Homo sapiens (Human) PR
Q9NQX1 PRDM5 PR domain zinc finger protein 5 Homo sapiens (Human) PR
Q9HBE1 PATZ1 POZ-, AT hook-, and zinc finger-containing protein 1 Homo sapiens (Human) PR
Q8TAX0 OSR1 Protein odd-skipped-related 1 Homo sapiens (Human) PR
Q8TBJ5 FEZF2 Fez family zinc finger protein 2 Homo sapiens (Human) PR
Q96SR6 ZNF382 Zinc finger protein 382 Homo sapiens (Human) PR
Q9ULJ3 ZBTB21 Zinc finger and BTB domain-containing protein 21 Homo sapiens (Human) PR
O75840 KLF7 Krueppel-like factor 7 Homo sapiens (Human) PR
Q13127 REST RE1-silencing transcription factor Homo sapiens (Human) PR
Q8IZM8 ZNF654 Zinc finger protein 654 Homo sapiens (Human) PR
Q14526 HIC1 Hypermethylated in cancer 1 protein Homo sapiens (Human) PR
Q06889 EGR3 Early growth response protein 3 Homo sapiens (Human) PR
Q08ER8 ZNF543 Zinc finger protein 543 Homo sapiens (Human) PR
Q8N680 ZBTB2 Zinc finger and BTB domain-containing protein 2 Homo sapiens (Human) PR
O95625 ZBTB11 Zinc finger and BTB domain-containing protein 11 Homo sapiens (Human) PR
Q96BV0 ZNF775 Zinc finger protein 775 Homo sapiens (Human) PR
Q5FWF6 ZNF789 Zinc finger protein 789 Homo sapiens (Human) PR
Q05516 ZBTB16 Zinc finger and BTB domain-containing protein 16 Homo sapiens (Human) PR
Q9H116 GZF1 GDNF-inducible zinc finger protein 1 Homo sapiens (Human) PR
Q8IW36 ZNF695 Zinc finger protein 695 Homo sapiens (Human) PR
Q5VTD9 GFI1B Zinc finger protein Gfi-1b Homo sapiens (Human) PR
Q6PG37 ZNF790 Zinc finger protein 790 Homo sapiens (Human) PR
Q9NQV6 PRDM10 PR domain zinc finger protein 10 Homo sapiens (Human) PR
Q9Y2D9 ZNF652 Zinc finger protein 652 Homo sapiens (Human) PR
Q5TC79 ZBTB37 Zinc finger and BTB domain-containing protein 37 Homo sapiens (Human) PR
Q9Y4E5 ZNF451 E3 SUMO-protein ligase ZNF451 Homo sapiens (Human) PR
Q8ND82 ZNF280C Zinc finger protein 280C Homo sapiens (Human) PR
Q49AA0 ZFP69 Zinc finger protein 69 homolog Homo sapiens (Human) PR
O43298 ZBTB43 Zinc finger and BTB domain-containing protein 43 Homo sapiens (Human) PR
Q9Y330 ZBTB12 Zinc finger and BTB domain-containing protein 12 Homo sapiens (Human) PR
Q13105 ZBTB17 Zinc finger and BTB domain-containing protein 17 Homo sapiens (Human) PR
P51508 ZNF81 Zinc finger protein 81 Homo sapiens (Human) PR
Q5JNZ3 ZNF311 Zinc finger protein 311 Homo sapiens (Human) PR
Q9Y4X4 KLF12 Krueppel-like factor 12 Homo sapiens (Human) PR
P10074 ZBTB48 Telomere zinc finger-associated protein Homo sapiens (Human) PR
P17010 ZFX Zinc finger X-chromosomal protein Homo sapiens (Human) PR
Q9H5H4 ZNF768 Zinc finger protein 768 Homo sapiens (Human) PR
Q9Y2L8 ZKSCAN5 Zinc finger protein with KRAB and SCAN domains 5 Homo sapiens (Human) PR
Q86UZ6 ZBTB46 Zinc finger and BTB domain-containing protein 46 Homo sapiens (Human) PR
Q8NCP5 ZBTB44 Zinc finger and BTB domain-containing protein 44 Homo sapiens (Human) PR
P41182 BCL6 B-cell lymphoma 6 protein Homo sapiens (Human) PR
Q9NQX0 PRDM6 Putative histone-lysine N-methyltransferase PRDM6 Homo sapiens (Human) PR
Q9BU19 ZNF692 Zinc finger protein 692 Homo sapiens (Human) PR
Q08AG5 ZNF844 Zinc finger protein 844 Homo sapiens (Human) PR
Q6R2W3 ZBED9 SCAN domain-containing protein 3 Homo sapiens (Human) PR
P98182 ZNF200 Zinc finger protein 200 Homo sapiens (Human) PR
Q9UK11 ZNF223 Zinc finger protein 223 Homo sapiens (Human) PR
O15156 ZBTB7B Zinc finger and BTB domain-containing protein 7B Homo sapiens (Human) PR
Q6ZMS7 ZNF783 Zinc finger protein 783 Homo sapiens (Human) PR
P59923 ZNF445 Zinc finger protein 445 Homo sapiens (Human) PR
Q8N859 ZNF713 Zinc finger protein 713 Homo sapiens (Human) PR
Q99612 KLF6 Krueppel-like factor 6 Homo sapiens (Human) PR
Q8TD17 ZNF398 Zinc finger protein 398 Homo sapiens (Human) PR
P52739 ZNF131 Zinc finger protein 131 Homo sapiens (Human) PR
Q05215 EGR4 Early growth response protein 4 Homo sapiens (Human) PR
Q7Z398 ZNF550 Zinc finger protein 550 Homo sapiens (Human) PR
Q9Y2K1 ZBTB1 Zinc finger and BTB domain-containing protein 1 Homo sapiens (Human) PR
Q96N20 ZNF75A Zinc finger protein 75A Homo sapiens (Human) PR
A1YPR0 ZBTB7C Zinc finger and BTB domain-containing protein 7C Homo sapiens (Human) PR
P24278 ZBTB25 Zinc finger and BTB domain-containing protein 25 Homo sapiens (Human) PR
Q96N38 ZNF714 Zinc finger protein 714 Homo sapiens (Human) PR
Q86YH2 ZNF280B Zinc finger protein 280B Homo sapiens (Human) PR
Q8NAM6 ZSCAN4 Zinc finger and SCAN domain-containing protein 4 Homo sapiens (Human) PR
Q9NPC7 MYNN Myoneurin Homo sapiens (Human) PR
O14978 ZNF263 Zinc finger protein 263 Homo sapiens (Human) PR
Q6P9G9 ZNF449 Zinc finger protein 449 Homo sapiens (Human) PR
O60304 ZNF500 Zinc finger protein 500 Homo sapiens (Human) PR
Q9NX65 ZSCAN32 Zinc finger and SCAN domain-containing protein 32 Homo sapiens (Human) PR
Q96IT1 ZNF496 Zinc finger protein 496 Homo sapiens (Human) PR
O14771 ZNF213 Zinc finger protein 213 Homo sapiens (Human) PR
O95125 ZNF202 Zinc finger protein 202 Homo sapiens (Human) PR
Q8IWY8 ZSCAN29 Zinc finger and SCAN domain-containing protein 29 Homo sapiens (Human) PR
Q8N0Y2 ZNF444 Zinc finger protein 444 Homo sapiens (Human) PR
A6NGD5 ZSCAN5C Zinc finger and SCAN domain-containing protein 5C Homo sapiens (Human) PR
A6NJL1 ZSCAN5B Zinc finger and SCAN domain-containing protein 5B Homo sapiens (Human) PR
Q8NF99 ZNF397 Zinc finger protein 397 Homo sapiens (Human) PR
Q86XF7 ZNF575 Zinc finger protein 575 Homo sapiens (Human) PR
Q9NWS9 ZNF446 Zinc finger protein 446 Homo sapiens (Human) PR
Q96N95 ZNF396 Zinc finger protein 396 Homo sapiens (Human) PR
Q9UL58 ZNF215 Zinc finger protein 215 Homo sapiens (Human) PR
P17029 ZKSCAN1 Zinc finger protein with KRAB and SCAN domains 1 Homo sapiens (Human) PR
Q53GI3 ZNF394 Zinc finger protein 394 Homo sapiens (Human) PR
Q9BRR0 ZKSCAN3 Zinc finger protein with KRAB and SCAN domains 3 Homo sapiens (Human) PR
Q969J2 ZKSCAN4 Zinc finger protein with KRAB and SCAN domains 4 Homo sapiens (Human) PR
Q6NSZ9 ZSCAN25 Zinc finger and SCAN domain-containing protein 25 Homo sapiens (Human) PR
Q9UNY5 ZNF232 Zinc finger protein 232 Homo sapiens (Human) PR
P17028 ZNF24 Zinc finger protein 24 Homo sapiens (Human) PR
Q63HK3 ZKSCAN2 Zinc finger protein with KRAB and SCAN domains 2 Homo sapiens (Human) PR
P49910 ZNF165 Zinc finger protein 165 Homo sapiens (Human) PR
Q15776 ZKSCAN8 Zinc finger protein with KRAB and SCAN domains 8 Homo sapiens (Human) PR
Q9H9D4 ZNF408 Zinc finger protein 408 Homo sapiens (Human) PR
O08584 Klf6 Krueppel-like factor 6 Mus musculus (Mouse) PR
Q61164 Ctcf Transcriptional repressor CTCF Mus musculus (Mouse) PR
Q8BGS3 Zkscan1 Zinc finger protein with KRAB and SCAN domains 1 Mus musculus (Mouse) PR
Q00899 Yy1 Transcriptional repressor protein YY1 Mus musculus (Mouse) PR
P41183 Bcl6 B-cell lymphoma 6 protein homolog Mus musculus (Mouse) PR
Q9DAI4 Zbtb43 Zinc finger and BTB domain-containing protein 43 Mus musculus (Mouse) PR
O70237 Gfi1b Zinc finger protein Gfi-1b Mus musculus (Mouse) PR
Q99KZ6 Znf639 Zinc finger protein 639 Mus musculus (Mouse) PR
Q9Z1D9 Znf394 Zinc finger protein 394 Mus musculus (Mouse) PR
Q9CXE0 Prdm5 PR domain zinc finger protein 5 Mus musculus (Mouse) PR
P43300 Egr3 Early growth response protein 3 Mus musculus (Mouse) PR
Q9DAU9 Znf654 Zinc finger protein 654 Mus musculus (Mouse) PR
Q9R1Y5 Hic1 Hypermethylated in cancer 1 protein Mus musculus (Mouse) PR
Q8R0T2 Znf768 Zinc finger protein 768 Mus musculus (Mouse) PR
Q9WVG7 Osr1 Protein odd-skipped-related 1 Mus musculus (Mouse) PR
Q8BI73 Znf775 Zinc finger protein 775 Mus musculus (Mouse) PR
Q8VCZ7 Zbtb7c Zinc finger and BTB domain-containing protein 7C Mus musculus (Mouse) PR
Q91VN1 Znf24 Zinc finger protein 24 Mus musculus (Mouse) PR
Q9DB38 Znf580 Zinc finger protein 580 Mus musculus (Mouse) PR
A7KBS4 Zscan4d Zinc finger and SCAN domain containing protein 4D Mus musculus (Mouse) PR
Q91VW9 Zkscan3 Zinc finger protein with KRAB and SCAN domains 3 Mus musculus (Mouse) PR
P10925 Zfy1 Zinc finger Y-chromosomal protein 1 Mus musculus (Mouse) PR
P08046 Egr1 Early growth response protein 1 Mus musculus (Mouse) PR
Q3TTC2 Yy2 Transcription factor YY2 Mus musculus (Mouse) PR
Q3UTQ7 Prdm10 PR domain zinc finger protein 10 Mus musculus (Mouse) PR
Q6P3Y5 Znf280c Zinc finger protein 280C Mus musculus (Mouse) PR
Q9ERU3 Znf22 Zinc finger protein 22 Mus musculus (Mouse) PR
Q8VIG1 Rest RE1-silencing transcription factor Mus musculus (Mouse) PR
Q9Z1D8 Zkscan5 Zinc finger protein with KRAB and SCAN domains 5 Mus musculus (Mouse) PR
Q8BID6 Zbtb46 Zinc finger and BTB domain-containing protein 46 Mus musculus (Mouse) PR
P17012 Zfx Zinc finger X-chromosomal protein Mus musculus (Mouse) PR
Q9WUK6 Zbtb18 Zinc finger and BTB domain-containing protein 18 Mus musculus (Mouse) PR
O35738 Klf12 Krueppel-like factor 12 Mus musculus (Mouse) PR
B2RXC5 Znf382 Zinc finger protein 382 Mus musculus (Mouse) PR
O08900 Ikzf3 Zinc finger protein Aiolos Mus musculus (Mouse) PR
Q5DU09 Znf652 Zinc finger protein 652 Mus musculus (Mouse) PR
Q5RJ54 Zscan26 Zinc finger and SCAN domain-containing protein 26 Mus musculus (Mouse) PR
Q8BLM0 Klf8 Krueppel-like factor 8 Mus musculus (Mouse) PR
Q99JB0 Klf7 Krueppel-like factor 7 Mus musculus (Mouse) PR
Q8R0A2 Zbtb44 Zinc finger and BTB domain-containing protein 44 Mus musculus (Mouse) PR
P20662 Zfy2 Zinc finger Y-chromosomal protein 2 Mus musculus (Mouse) PR
Q80VJ6 Zscan4c Zinc finger and SCAN domain containing protein 4C Mus musculus (Mouse) PR
Q3URS2 Zscan4f Zinc finger and SCAN domain containing protein 4F Mus musculus (Mouse) PR
Q60980 Klf3 Krueppel-like factor 3 Mus musculus (Mouse) PR
Q8K3J5 Znf131 Zinc finger protein 131 Mus musculus (Mouse) PR
Q810A1 Znf18 Zinc finger protein 18 Mus musculus (Mouse) PR
Q9Z2K3 Znf394 Zinc finger protein 394 Rattus norvegicus (Rat) PR
B0K011 Osr1 Protein odd-skipped-related 1 Rattus norvegicus (Rat) PR
D3ZUU2 Gzf1 GDNF-inducible zinc finger protein 1 Rattus norvegicus (Rat) PR
B1WBU4 Zbtb8a Zinc finger and BTB domain-containing protein 8A Rattus norvegicus (Rat) PR
Q7TNK3 Znf24 Zinc finger protein 24 Rattus norvegicus (Rat) PR
O35819 Klf6 Krueppel-like factor 6 Rattus norvegicus (Rat) PR
Q9R1D1 Ctcf Transcriptional repressor CTCF Rattus norvegicus (Rat) PR
P43301 Egr3 Early growth response protein 3 Rattus norvegicus (Rat) PR
P08154 Egr1 Early growth response protein 1 Rattus norvegicus (Rat) PR
A0JPL0 Znf382 Zinc finger protein 382 Rattus norvegicus (Rat) PR
Q4KLI1 Zkscan1 Zinc finger protein with KRAB and SCAN domains 1 Rattus norvegicus (Rat) PR
A1L1J6 Znf652 Zinc finger protein 652 Rattus norvegicus (Rat) PR
Q642B9 Znf18 Zinc finger protein 18 Rattus norvegicus (Rat) PR
Q9SHD0 ZAT4 Zinc finger protein ZAT4 Arabidopsis thaliana (Mouse-ear cress) PR
Q0P4X6 zbtb44 Zinc finger and BTB domain-containing protein 44 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
A4II20 egr1 Early growth response protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q6P882 zbtb8a.2 Zinc finger and BTB domain-containing protein 8A.2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
Q567C6 znf367 Zinc finger protein 367 Danio rerio (Zebrafish) (Brachydanio rerio) PR
A7Y7X5 znf711 Zinc finger protein 711 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MPVDLGQALG LLPSLAKAED SQFSESDAAL QEELSSPETA RQLFRQFRYQ VMSGPHETLK
70 80 90 100 110 120
QLRKLCFQWL QPEVHTKEQI LEILMLEQFL TILPGEIQMW VRKQCPGSGE EAVTLVESLK
130 140 150 160 170 180
GDPQRLWQWI SIQVLGQDIL SEKMESPSCQ VGEVEPHLEV VPQELGLENS SSGPGELLSH
190 200 210 220 230 240
IVKEESDTEA ELALAASQPA RLEERLIRDQ DLGASLLPAA PQEQWRQLDS TQKEQYWDLM
250 260 270 280 290 300
LETYGKMVSG AGISHPKSDL TNSIEFGEEL AGIYLHVNEK IPRPTCIGDR QENDKENLNL
310 320 330 340 350 360
ENHRDQELLH ASCQASGEVP SQASLRGFFT EDEPGCFGEG ENLPEALQNI QDEGTGEQLS
370 380 390 400 410 420
PQERISEKQL GQHLPNPHSG EMSTMWLEEK RETSQKGQPR APMAQKLPTC RECGKTFYRN
430 440 450 460 470 480
SQLIFHQRTH TGETYFQCTI CKKAFLRSSD FVKHQRTHTG EKPCKCDYCG KGFSDFSGLR
490 500 510 520 530 540
HHEKIHTGEK PYKCPICEKS FIQRSNFNRH QRVHTGEKPY KCSHCGKSFS WSSSLDKHQR
SHLGKKPFQ