P0DC86

PR
Gene name
yidC1
Protein name
Membrane protein insertase YidC 1
Names
Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1
Species
Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
KEGG Pathway
spg:SpyM3_0176
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

223-275 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0DC86

Entry ID Method Resolution Chain Position Source
AF-P0DC86-F1 Predicted AlphaFoldDB

No variants for P0DC86

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0DC86

No associated diseases with P0DC86

2 regional properties for P0DC86

Type Name Position InterPro Accession
domain Membrane insertase YidC/Oxa/ALB, C-terminal 58 - 241 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 60 - 242 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRKVLRVKKN IKIARIVPLV LLLVACGRGE VTAQSSSGWD QLVYLFARAI QWLSFDGSIG
70 80 90 100 110 120
VGIILFTLTI RLMLMPLFNM QIKSSQKMQD IQPELRELQR KYAGKDTQTR MKLAEESQAL
130 140 150 160 170 180
YKKYGVNPYA SLLPLLIQMP VMIALFQALT RVSFLKTGTF LWVELAQHDH LYLLPVLAAV
190 200 210 220 230 240
FTFLSTWLTN LAAKEKNVMM TVMIYVMPLM IFFMGFNLAS GVVLYWTVSN AFQVVQLLLL
250 260 270
NNPFKIIAER QRLANEEKER RLRERRARKK AMKRK