P0CH02
PR
Gene name |
ATL21B (At2g46494, F11C10, F13A10) |
Protein name |
Putative RING-H2 finger protein ATL21B |
Names |
RING-type E3 ubiquitin transferase ATL21B |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G46494 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CH02
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CH02-F1 | Predicted | AlphaFoldDB |
69 variants for P0CH02
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05728677 | 2 | I>K | No | 1000Genomes | |
| ENSVATH00277237 | 2 | I>V | No | 1000Genomes | |
| tmp_2_19083793_G_A | 7 | L>F | No | 1000Genomes | |
| tmp_2_19083741_G_A | 24 | S>L | No | 1000Genomes | |
| tmp_2_19083711_G_A | 34 | S>L | No | 1000Genomes | |
| ENSVATH14621201 | 37 | H>R | No | 1000Genomes | |
| ENSVATH05728675 | 52 | D>N | No | 1000Genomes | |
| tmp_2_19083630_G_C | 61 | T>S | No | 1000Genomes | |
| ENSVATH01994451 | 70 | L>F | No | 1000Genomes | |
| ENSVATH05728674 | 80 | Y>D | No | 1000Genomes | |
| tmp_2_19083565_A_T | 83 | Y>N | No | 1000Genomes | |
| ENSVATH13656133 | 87 | Q>P | No | 1000Genomes | |
| ENSVATH05728673 | 91 | N>K | No | 1000Genomes | |
| ENSVATH05728670 | 100 | R>M | No | 1000Genomes | |
| ENSVATH13656131 | 113 | P>A | No | 1000Genomes | |
| tmp_2_19083462_G_A | 117 | T>I | No | 1000Genomes | |
| tmp_2_19083459_A_T | 118 | L>* | No | 1000Genomes | |
| tmp_2_19083458_T_G | 118 | L>F | No | 1000Genomes | |
| tmp_2_19083457_A_T | 119 | Y>N | No | 1000Genomes | |
| ENSVATH13656130 | 120 | T>S | No | 1000Genomes | |
| tmp_2_19083445_T_C | 123 | T>A | No | 1000Genomes | |
| tmp_2_19083430_G_C,T | 128 | L>I | No | 1000Genomes | |
| tmp_2_19083430_G_C,T | 128 | L>V | No | 1000Genomes | |
| tmp_2_19083400_G_A | 138 | P>S | No | 1000Genomes | |
| ENSVATH01994450 | 145 | S>F | No | 1000Genomes | |
| ENSVATH13656127 | 157 | E>Q | No | 1000Genomes | |
| ENSVATH01994449 | 168 | R>I | No | 1000Genomes | |
| ENSVATH13656126 | 169 | I>L | No | 1000Genomes | |
| tmp_2_19083303_T_C | 170 | Y>C | No | 1000Genomes | |
| tmp_2_19083304_A_G | 170 | Y>H | No | 1000Genomes | |
| ENSVATH00277234 | 173 | A>V | No | 1000Genomes | |
| tmp_2_19083292_C_G | 174 | D>H | No | 1000Genomes | |
| tmp_2_19083281_A_T | 177 | F>L | No | 1000Genomes | |
| ENSVATH05728668 | 177 | F>S | No | 1000Genomes | |
| tmp_2_19083270_C_T | 181 | R>K | No | 1000Genomes | |
| tmp_2_19083243_A_T | 190 | L>H | No | 1000Genomes | |
| ENSVATH01994448 | 205 | D>E | No | 1000Genomes | |
| tmp_2_19083183_C_A | 210 | G>V | No | 1000Genomes | |
| ENSVATH13656104 | 211 | F>L | No | 1000Genomes | |
| tmp_2_19083165_G_A | 216 | S>F | No | 1000Genomes | |
| ENSVATH13656102 | 217 | P>L | No | 1000Genomes | |
| ENSVATH01994447 | 218 | E>K | No | 1000Genomes | |
| ENSVATH01994447 | 218 | E>Q | No | 1000Genomes | |
| tmp_2_19083132_G_A | 227 | S>F | No | 1000Genomes | |
| tmp_2_19083133_A_T | 227 | S>T | No | 1000Genomes | |
| ENSVATH01994441 | 232 | R>K | No | 1000Genomes | |
| ENSVATH01994440 | 232 | R>S | No | 1000Genomes | |
| ENSVATH01994439 | 248 | I>T | No | 1000Genomes | |
| tmp_2_19082665_G_C | 256 | I>M | No | 1000Genomes | |
| tmp_2_19082652_T_C | 261 | T>A | No | 1000Genomes | |
| tmp_2_19082649_G_C | 262 | P>A | No | 1000Genomes | |
| ENSVATH00277230 | 268 | A>S | No | 1000Genomes | |
| tmp_2_19082609_G_C | 275 | T>S | No | 1000Genomes | |
| tmp_2_19082607_C_T | 276 | V>I | No | 1000Genomes | |
| ENSVATH00277229 | 283 | V>F | No | 1000Genomes | |
| ENSVATH05728655 | 285 | A>S | No | 1000Genomes | |
| tmp_2_19082568_G_A | 289 | L>F | No | 1000Genomes | |
| ENSVATH05728654 | 292 | S>Y | No | 1000Genomes | |
| tmp_2_19082539_C_G | 298 | K>N | No | 1000Genomes | |
| tmp_2_19082533_C_T | 300 | M>I | No | 1000Genomes | |
| tmp_2_19082522_T_C | 304 | E>G | No | 1000Genomes | |
| tmp_2_19082518_A_T | 305 | S>R | No | 1000Genomes | |
| ENSVATH01994437 | 315 | V>I | No | 1000Genomes | |
| ENSVATH05728653 | 324 | V>A | No | 1000Genomes | |
| tmp_2_19082459_C_T | 325 | S>N | No | 1000Genomes | |
| ENSVATH05728650 | 332 | I>K | No | 1000Genomes | |
| tmp_2_19082436_G_A | 333 | P>S | No | 1000Genomes | |
| ENSVATH00277228 | 340 | H>N | No | 1000Genomes | |
| tmp_2_19082356_G_T | 359 | N>K | No | 1000Genomes |
No associated diseases with P0CH02
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| polysaccharide binding | Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. |
| transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VE61 | CG7694 | E3 ubiquitin-protein ligase RNF181 homolog | Drosophila melanogaster (Fruit fly) | PR |
| O00237 | RNF103 | E3 ubiquitin-protein ligase RNF103 | Homo sapiens (Human) | PR |
| Q86Y13 | DZIP3 | E3 ubiquitin-protein ligase DZIP3 | Homo sapiens (Human) | PR |
| Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | Homo sapiens (Human) | EV |
| Q9R1W3 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Mus musculus (Mouse) | PR |
| Q9EPZ8 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Rattus norvegicus (Rat) | PR |
| Q9SI09 | XERICO | Probable E3 ubiquitin-protein ligase XERICO | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZV51 | ATL56 | RING-H2 finger protein ATL56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22255 | ATL64 | RING-H2 finger protein ATL64 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RXX9 | ATL6 | E3 ubiquitin-protein ligase ATL6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYT9 | SIS3 | E3 ubiquitin-protein ligase SIS3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZJ6 | ATL5 | RING-H2 finger protein ATL5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXF8 | SGR9 | E3 ubiquitin-protein ligase SGR9, amyloplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LGA5 | ATL31 | E3 ubiquitin-protein ligase ATL31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUZ9 | ATL63 | RING-H2 finger protein ATL63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH01 | ATL21A | Putative RING-H2 finger protein ATL21A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKK8 | ATL22 | RING-H2 finger protein ATL22 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIISKQLFLL | FFLLFFIFPL | RHASNPSKCS | SSNSRPHRCG | PLEVPIRFPF | CDHPLFNLLC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TNLNNTVLQL | PMSGTFFVQY | IDYRKQQIYI | NDPENCLAKR | LLTFNISGSP | FSPRFDTLYT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLTCPNELVL | PSWYPSIPCL | SNSTSSFFAT | SNFALAESML | PSCQIVKRIY | VPADSPFAET |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RFSSYLNQSL | LLEWNSPNCR | GCEIDYLRCG | FKNKASPEVK | CFGAKKSGHL | SRAVVAVLIC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSIIGAVILF | VTCIAIRIHN | TPRRRHWAVP | AAAATVMQQP | REVMATRGLD | QSTIEKYKTM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELGESRRPPG | TNGIVCPICL | SEYVSKETVR | FIPECDHCFH | AKCIDVWLKI | HGSCPLCRNS |
| RA |