P0CH01
Gene name |
ATL21A (At2g46495, F11C10, F13A10) |
Protein name |
Putative RING-H2 finger protein ATL21A |
Names |
RING-type E3 ubiquitin transferase ATL21A |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G46495 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CH01
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CH01-F1 | Predicted | AlphaFoldDB |
26 variants for P0CH01
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_19085692_T_G | 5 | K>Q | No | 1000Genomes | |
| tmp_2_19085679_A_T | 9 | L>H | No | 1000Genomes | |
| ENSVATH13656186 | 19 | H>D | No | 1000Genomes | |
| tmp_2_19085608_G_C | 33 | R>G | No | 1000Genomes | |
| ENSVATH05728718 | 34 | D>N | No | 1000Genomes | |
| ENSVATH14621209 | 47 | K>N | No | 1000Genomes | |
| ENSVATH14621208 | 64 | S>N | No | 1000Genomes | |
| ENSVATH13656182 | 88 | Q>K | No | 1000Genomes | |
| tmp_2_19085333_G_T | 124 | S>R | No | 1000Genomes | |
| ENSVATH01994464 | 154 | L>V | No | 1000Genomes | |
| tmp_2_19085229_G_A | 159 | S>F | No | 1000Genomes | |
| ENSVATH00277243 | 171 | D>A | No | 1000Genomes | |
| ENSVATH05728710 | 172 | V>I | No | 1000Genomes | |
| ENSVATH05728709 | 187 | T>A | No | 1000Genomes | |
| ENSVATH13656180 | 216 | R>I | No | 1000Genomes | |
| ENSVATH05728708 | 228 | F>Y | No | 1000Genomes | |
| ENSVATH00277239 | 234 | N>D | No | 1000Genomes | |
| ENSVATH05728696 | 237 | P>S | No | 1000Genomes | |
| tmp_2_19084530_C_A | 241 | K>N | No | 1000Genomes | |
| ENSVATH05728695 | 251 | L>I | No | 1000Genomes | |
| ENSVATH13656162 | 252 | T>M | No | 1000Genomes | |
| tmp_2_19084447_G_A | 269 | A>V | No | 1000Genomes | |
| tmp_2_19084436_G_C | 273 | Q>E | No | 1000Genomes | |
| ENSVATH05728689 | 345 | S>G | No | 1000Genomes | |
| ENSVATH05728688 | 345 | S>I | No | 1000Genomes | |
| ENSVATH01994457 | 348 | I>V | No | 1000Genomes |
No associated diseases with P0CH01
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| polysaccharide binding | Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. |
| transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VE61 | CG7694 | E3 ubiquitin-protein ligase RNF181 homolog | Drosophila melanogaster (Fruit fly) | PR |
| O00237 | RNF103 | E3 ubiquitin-protein ligase RNF103 | Homo sapiens (Human) | PR |
| Q86Y13 | DZIP3 | E3 ubiquitin-protein ligase DZIP3 | Homo sapiens (Human) | PR |
| Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | Homo sapiens (Human) | EV |
| Q9R1W3 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Mus musculus (Mouse) | PR |
| Q9EPZ8 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Rattus norvegicus (Rat) | PR |
| Q9SI09 | XERICO | Probable E3 ubiquitin-protein ligase XERICO | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZV51 | ATL56 | RING-H2 finger protein ATL56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22255 | ATL64 | RING-H2 finger protein ATL64 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RXX9 | ATL6 | E3 ubiquitin-protein ligase ATL6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYT9 | SIS3 | E3 ubiquitin-protein ligase SIS3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZJ6 | ATL5 | RING-H2 finger protein ATL5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXF8 | SGR9 | E3 ubiquitin-protein ligase SGR9, amyloplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LGA5 | ATL31 | E3 ubiquitin-protein ligase ATL31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUZ9 | ATL63 | RING-H2 finger protein ATL63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH02 | ATL21B | Putative RING-H2 finger protein ATL21B | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKK8 | ATL22 | RING-H2 finger protein ATL22 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTFSKQLFLY | LFFLFPLLHA | SHPQQCSSSS | CGRDDVHVRF | PFWLLSKQPE | LCGHAGFNLQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CTASPKTALK | LPNSGTFLVR | EIDYLSQQIR | LYDPENCLAR | KLLTFDISRS | PFSALYLVSY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TFLSCPNEVA | KSSRFDSIPC | LGNSTTSFLA | TTSLDLAKSM | LPSCQIVKTL | DVPVSRRVIA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KKSRFSTDVN | DKDLWLKWDS | PSCSDCERDF | LRCGFRSNTS | LQVKCFPFEN | SGYNTEPQVL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KIILLSIIGP | LTIFATCIAV | GVCTSERFAS | LIQRNVAIAA | LQPNEVIVTT | GLDESIIESY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KKTELGESRR | LPGNNDDIVC | PICLSEYASK | ETVRCIPECD | HCFHSECIDV | WLKIHGSCPL |
| 370 | |||||
| CRNSPSPARQ | AV |