Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P0C2F7

Entry ID Method Resolution Chain Position Source
AF-P0C2F7-F1 Predicted AlphaFoldDB

82 variants for P0C2F7

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_6741299_G_A 2 V>I No 1000Genomes
ENSVATH04603089 3 N>I No 1000Genomes
tmp_1_6741340_C_A 15 C>* No 1000Genomes
tmp_1_6741338_T_G 15 C>G No 1000Genomes
ENSVATH13926703 16 D>N No 1000Genomes
tmp_1_6741357_C_T 21 P>L No 1000Genomes
ENSVATH01071739 24 Q>E No 1000Genomes
ENSVATH01071741 27 R>K No 1000Genomes
ENSVATH04603091 33 A>T No 1000Genomes
ENSVATH01071743 49 E>K No 1000Genomes
ENSVATH13926704 50 D>H No 1000Genomes
ENSVATH01071744 54 V>I No 1000Genomes
ENSVATH01071746 93 G>E No 1000Genomes
tmp_1_6741623_G_A 110 A>T No 1000Genomes
ENSVATH01071748 111 A>T No 1000Genomes
ENSVATH07518613 113 K>Q No 1000Genomes
ENSVATH07518614 113 K>R No 1000Genomes
ENSVATH07518615 119 P>A No 1000Genomes
ENSVATH04603095 120 A>P No 1000Genomes
ENSVATH01071749 129 K>M No 1000Genomes
tmp_1_6741687_C_G 131 S>C No 1000Genomes
tmp_1_6741710_G_A 139 G>S No 1000Genomes
ENSVATH11546167 139 G>V No 1000Genomes
tmp_1_6741741_C_T 149 S>F No 1000Genomes
tmp_1_6741777_G_A 161 G>D No 1000Genomes
tmp_1_6741779_G_A 162 G>R No 1000Genomes
tmp_1_6741789_A_G 165 D>G No 1000Genomes
ENSVATH01071750 171 L>V No 1000Genomes
ENSVATH13926705 181 K>N No 1000Genomes
ENSVATH04603097 183 R>C No 1000Genomes
ENSVATH11546170 187 S>C No 1000Genomes
ENSVATH00032219 200 V>F No 1000Genomes
tmp_1_6741896_G_A 201 D>N No 1000Genomes
tmp_1_6741903_A_C 203 K>T No 1000Genomes
tmp_1_6741911_G_A 206 V>I No 1000Genomes
ENSVATH11546171 207 I>V No 1000Genomes
ENSVATH11546172 222 V>L No 1000Genomes
tmp_1_6742001_C_A 236 P>T No 1000Genomes
ENSVATH00032220 239 R>K No 1000Genomes
ENSVATH01071752 242 A>S No 1000Genomes
ENSVATH01071753 243 G>C No 1000Genomes
ENSVATH01071754 244 S>C No 1000Genomes
ENSVATH01071755 245 Q>E No 1000Genomes
tmp_1_6742033_T_G 246 F>L No 1000Genomes
tmp_1_6742034_T_G 247 S>A No 1000Genomes
tmp_1_6742035_C_A 247 S>Y No 1000Genomes
ENSVATH11546286 249 H>Y No 1000Genomes
ENSVATH01071756 250 A>V No 1000Genomes
ENSVATH01071757 254 D>E No 1000Genomes
ENSVATH01071759 260 G>S No 1000Genomes
ENSVATH04603100 262 K>* No 1000Genomes
tmp_1_6742084_T_A 263 F>L No 1000Genomes
tmp_1_6742106_A_T,C 271 R>* No 1000Genomes
tmp_1_6742145_T_G 284 L>V No 1000Genomes
ENSVATH04603102 296 D>N No 1000Genomes
tmp_1_6742189_G_C 298 M>I No 1000Genomes
tmp_1_6742223_C_T 310 H>Y No 1000Genomes
ENSVATH09371530 316 H>N No 1000Genomes
ENSVATH01071760 321 T>S No 1000Genomes
ENSVATH01071762 331 W>G No 1000Genomes
tmp_1_6742307_T_G 338 F>V No 1000Genomes
tmp_1_6742313_A_G 340 K>E No 1000Genomes
tmp_1_6742325_G_A 344 A>T No 1000Genomes
tmp_1_6742345_G_T 350 L>F No 1000Genomes
ENSVATH00032222
ENSVATH00032221
355 S>R No 1000Genomes
ENSVATH11546289 356 N>H No 1000Genomes
ENSVATH11546291 357 K>E No 1000Genomes
tmp_1_6742365_A_G 357 K>R No 1000Genomes
tmp_1_6742374_T_A 360 V>D No 1000Genomes
tmp_1_6742373_G_A 360 V>I No 1000Genomes
ENSVATH00032223 361 T>P No 1000Genomes
ENSVATH04603105 367 E>K No 1000Genomes
ENSVATH01071763 374 M>I No 1000Genomes
ENSVATH01071764 392 L>F No 1000Genomes
ENSVATH01071765 396 L>F No 1000Genomes
ENSVATH01071766 398 D>Y No 1000Genomes
ENSVATH01071767 400 N>D No 1000Genomes
ENSVATH01071768 401 F>I No 1000Genomes
ENSVATH01071769 402 L>V No 1000Genomes
ENSVATH01071770 405 R>G No 1000Genomes
ENSVATH01071771 408 Q>R No 1000Genomes
ENSVATH01071772 409 T>S No 1000Genomes

No associated diseases with P0C2F7

1 regional properties for P0C2F7

Type Name Position InterPro Accession
repeat Kelch repeat type 1 147 - 249 IPR006652

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
B1WBU4 Zbtb8a Zinc finger and BTB domain-containing protein 8A Rattus norvegicus (Rat) PR
O82374 At2g29820 Putative F-box/kelch-repeat protein At2g29820 Arabidopsis thaliana (Mouse-ear cress) PR
O82376 At2g29800 Putative F-box/kelch-repeat protein At2g29800 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PE09 At4g39753 F-box/kelch-repeat protein At4g39753 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PF20 At2g22050 F-box/kelch-repeat protein At2g22050 Arabidopsis thaliana (Mouse-ear cress) PR
Q6P882 zbtb8a.2 Zinc finger and BTB domain-containing protein 8A.2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MVNISEIPDD SNDGCDPNKK PEEQVLRRSR RIATRNENQN KKPKEEEEED NRSVSFPIPN
70 80 90 100 110 120
ELTEACVALI RKCDYPSLSS VSSYFFNLIA SSGLYETRSR LGLSETFLYA AIKFPDTNPA
130 140 150 160 170 180
NWYILHRNKV SSLRLTEVGS LPPVPWGCSV VTVGQEMYVI GGLLDIRRLQ LMTLIDCRTH
190 200 210 220 230 240
KCRSLPSMKR GRYKAAAGVV DGKIYVIGGF RMRKPDAEWI EVFDLKTQIW ESLPGPYPRT
250 260 270 280 290 300
SAGSQFSAHA VMEDKLYMLG SKFCLVYEPK RNGEWDASVG ATPLKDLWDK TCCVVDDMLY
310 320 330 340 350 360
TTDPRRTLGH PIVVYHPKDK TWRPVKGESL WSLPSYFFSK SEMANFGGKL VILGSNKSYV
370 380 390 400 410
TGDCIGEKGI WCVMIELEKR EGGEIWGKVE SLDCVLGDIN FLSVRLCQTL TI