P0ADE8

PR
Gene name
ygfZ (yzzW, b2898, JW2866)
Protein name
tRNA-modifying protein YgfZ
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b2898
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P0ADE8

Entry ID Method Resolution Chain Position Source
1NRK X-ray 280 A A 1-325 PDB
1VLY X-ray 130 A A 1-326 PDB
AF-P0ADE8-F1 Predicted AlphaFoldDB

No variants for P0ADE8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0ADE8

No associated diseases with P0ADE8

2 regional properties for P0ADE8

Type Name Position InterPro Accession
domain Aminomethyltransferase, folate-binding domain 31 - 135 IPR006222
conserved_site YgfZ/GcvT conserved site 187 - 251 IPR017703

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

1 GO annotations of molecular function

Name Definition
folic acid binding Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.

3 GO annotations of biological process

Name Definition
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
RNA modification The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
tRNA processing The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFTPFPPRQ PTASARLPLT LMTLDDWALA TITGADSEKY MQGQVTADVS QMAEDQHLLA
70 80 90 100 110 120
AHCDAKGKMW SNLRLFRDGD GFAWIERRSV REPQLTELKK YAVFSKVTIA PDDERVLLGV
130 140 150 160 170 180
AGFQARAALA NLFSELPSKE KQVVKEGATT LLWFEHPAER FLIVTDEATA NMLTDKLRGE
190 200 210 220 230 240
AELNNSQQWL ALNIEAGFPV IDAANSGQFI PQATNLQALG GISFKKGCYT GQEMVARAKF
250 260 270 280 290 300
RGANKRALWL LAGSASRLPE AGEDLELKMG ENWRRTGTVL AAVKLEDGQV VVQVVMNNDM
310 320
EPDSIFRVRD DANTLHIEPL PYSLEE