P0ABR8

PR
Gene name
yeaW (Z2845, ECs2511)
Protein name
Carnitine monooxygenase oxygenase subunit
Names
Carnitine monooxygenase alpha subunit
Species
Escherichia coli O157:H7
KEGG Pathway
ecs:ECs_2511
EC number
1.14.13.239: With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

307-374 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0ABR8

Entry ID Method Resolution Chain Position Source
AF-P0ABR8-F1 Predicted AlphaFoldDB

No variants for P0ABR8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0ABR8

No associated diseases with P0ABR8

3 regional properties for P0ABR8

Type Name Position InterPro Accession
domain Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain 184 - 370 IPR015879
binding_site Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site 89 - 112 IPR015881
domain Rieske [2Fe-2S] iron-sulphur domain 46 - 155 IPR017941

Functions

Description
EC Number 1.14.13.239 With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
2 iron, 2 sulfur cluster binding Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
iron ion binding Binding to an iron (Fe) ion.
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

1 GO annotations of biological process

Name Definition
carnitine metabolic process The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNLSPDFVL PENFCANPQE AWTIPARFYT DQNAFEHEKE NVFAKSWICV AHSSELANAN
70 80 90 100 110 120
DYVTREIIGE SIVLVRGRDK VLRAFYNVCP HRGHQLLSGE GKAKNVITCP YHAWAFKLDG
130 140 150 160 170 180
NLAHARNCEN VANFDSDKAQ LVPVRLEEYA GFVFINMDPN ATSVEDQLPG LGAKVLEACP
190 200 210 220 230 240
EVHDLKLAAR FTTRTPANWK NIVDNYLECY HCGPAHPGFS DSVQVDRYWH TMHGNWTLQY
250 260 270 280 290 300
GFAKPSEQSF KFEEGTDAAF HGFWLWPCTM LNVTPIKGMM TVIYEFPVDS ETTLQNYDIY
310 320 330 340 350 360
FTNEELTDEQ KSLIEWYRDV FRPEDLRLVE SVQKGLKSRG YRGQGRIMAD SSGSGISEHG
370
IAHFHNLLAQ VFKD