O94655

PR
Gene name
ypt7 (SPBC405.04c)
Protein name
Ypt/Rab-type GTPase ypt7
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC405.04c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

148-205 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O94655

Entry ID Method Resolution Chain Position Source
AF-O94655-F1 Predicted AlphaFoldDB

No variants for O94655

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O94655

No associated diseases with O94655

No regional properties for O94655

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O94655

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
fungal-type vacuole membrane The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
late endosome A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
phagocytic vesicle A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

7 GO annotations of biological process

Name Definition
endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
Golgi to vacuole transport The directed movement of substances from the Golgi to the vacuole.
intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
positive regulation of vacuole fusion, non-autophagic Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
regulation of vacuole fusion, non-autophagic Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
vacuole fusion, non-autophagic The fusion of two vacuole membranes to form a single vacuole.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGKKKHLLK VIILGESGVG KTSIMNQYVN RKFSKDYKAT IGADFLTKEV LVDDKVVTLQ
70 80 90 100 110 120
LWDTAGQERF QSLGVAFYRG ADCCVLVYDV NNSKSFETLD SWRDEFLIQA SPSNPETFPF
130 140 150 160 170 180
ILLGNKVDVE EQKRMVSKSK ALAFCQARGE IPYFETSAKE AINVQEAFET VAKLALENMD
190 200
SDDIAADFTD PIHLDMESQK TSCYC