Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O82376

Entry ID Method Resolution Chain Position Source
AF-O82376-F1 Predicted AlphaFoldDB

56 variants for O82376

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_12724565_T_C 13 N>S No 1000Genomes
ENSVATH05626410 35 Q>H No 1000Genomes
ENSVATH05626409 36 N>Y No 1000Genomes
ENSVATH01925252 41 E>D No 1000Genomes
tmp_2_12724479_C_T 42 A>T No 1000Genomes
tmp_2_12724468_T_G 45 E>D No 1000Genomes
ENSVATH13471417 47 D>N No 1000Genomes
tmp_2_12724455_C_G 50 D>H No 1000Genomes
ENSVATH01925251 56 V>L No 1000Genomes
tmp_2_12724424_G_A 60 P>L No 1000Genomes
ENSVATH13471416 78 C>Y No 1000Genomes
tmp_2_12724334_A_G 90 F>S No 1000Genomes
tmp_2_12724319_G_T 95 S>Y No 1000Genomes
tmp_2_12724313_T_A 97 E>V No 1000Genomes
tmp_2_12724298_A_G 102 V>A No 1000Genomes
tmp_2_12724299_C_T 102 V>I No 1000Genomes
tmp_2_12724293_A_G 104 S>P No 1000Genomes
ENSVATH05626408 107 G>R No 1000Genomes
ENSVATH00254116 111 P>R No 1000Genomes
tmp_2_12724272_G_A 111 P>S No 1000Genomes
tmp_2_12724269_C_G 112 V>L No 1000Genomes
tmp_2_12724251_T_A 118 T>S No 1000Genomes
ENSVATH00254115 120 K>N No 1000Genomes
tmp_2_12724233_A_T 124 F>I No 1000Genomes
ENSVATH05626407 128 R>T No 1000Genomes
tmp_2_12724216_C_T 129 W>* No 1000Genomes
ENSVATH13471415 129 W>S No 1000Genomes
tmp_2_12724131_C_T 158 V>I No 1000Genomes
ENSVATH01925249 167 V>M No 1000Genomes
ENSVATH13471403 176 K>N No 1000Genomes
ENSVATH05626406 184 I>M No 1000Genomes
ENSVATH05626405 185 D>N No 1000Genomes
tmp_2_12724046_C_T 186 C>Y No 1000Genomes
ENSVATH00254114 200 D>H No 1000Genomes
ENSVATH00254114 200 D>N No 1000Genomes
tmp_2_12723953_G_A 217 A>V No 1000Genomes
ENSVATH00254113 222 R>Q No 1000Genomes
ENSVATH13471402 231 D>N No 1000Genomes
tmp_2_12723904_C_A 233 E>D No 1000Genomes
tmp_2_12723882_G_A 241 P>S No 1000Genomes
ENSVATH00254112 271 Y>C No 1000Genomes
ENSVATH05626404 284 T>A No 1000Genomes
tmp_2_12723725_C_T 293 S>N No 1000Genomes
ENSVATH14570236 312 R>L No 1000Genomes
tmp_2_12723662_A_T 314 I>N No 1000Genomes
ENSVATH05626403 317 A>V No 1000Genomes
ENSVATH05626402 336 E>K No 1000Genomes
ENSVATH14570235 349 A>V No 1000Genomes
ENSVATH13471399 351 F>L No 1000Genomes
ENSVATH05626400 353 G>E No 1000Genomes
tmp_2_12723543_T_C 354 K>E No 1000Genomes
tmp_2_12723531_A_C 358 L>V No 1000Genomes
ENSVATH13471398 368 Y>C No 1000Genomes
ENSVATH13471397 380 E>K No 1000Genomes
ENSVATH05626399 394 L>H No 1000Genomes
ENSVATH00254111 414 I>V No 1000Genomes

No associated diseases with O82376

1 regional properties for O82376

Type Name Position InterPro Accession
repeat Kelch repeat type 1 153 - 252 IPR006652

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
B1WBU4 Zbtb8a Zinc finger and BTB domain-containing protein 8A Rattus norvegicus (Rat) PR
O82374 At2g29820 Putative F-box/kelch-repeat protein At2g29820 Arabidopsis thaliana (Mouse-ear cress) PR
P0C2F7 At1g19470 Kelch repeat-containing protein At1g19470 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PE09 At4g39753 F-box/kelch-repeat protein At4g39753 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PF20 At2g22050 F-box/kelch-repeat protein At2g22050 Arabidopsis thaliana (Mouse-ear cress) PR
Q6P882 zbtb8a.2 Zinc finger and BTB domain-containing protein 8A.2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MASISETSDD GSNGGVPNQK PEEPHKNPQE EKENQNENPN EADEEDDHQD EEVENVPPIP
70 80 90 100 110 120
RKIPPVLIEN TIAPLRRCHY PKLSLLSNAF RQVISSEDLF QVRSLIGSTE PVLYTLITFK
130 140 150 160 170 180
YPTFEEGRWF ILQRRNNTSL KLNCVTSLPP MFLGCTAVTI GHKIYVVGGY NFRYNKTIST
190 200 210 220 230 240
VLEIDCRFNT CRHLRNMKRD RCSAVAGVID GRIYVVAGRQ RRFDDWVEVF DVETERWELV
250 260 270 280 290 300
PGPFSSFASS SGKFIVHVVL DNKIYIMDGD YCFAYDPRRR RWETWGPESA QRSYWHLSSC
310 320 330 340 350 360
VVDDLLYAIV PREIFGASIV VYDPRGIAWR PVMGLEFWPN LVYFESKMAN FGGKLVILGC
370 380 390 400 410
YRSSFDYYRK DVWCVEVALE KHEDGQIWGK VESLSLVNAF PMSPFFELSR TVTI