Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O82374

Entry ID Method Resolution Chain Position Source
AF-O82374-F1 Predicted AlphaFoldDB

79 variants for O82374

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_12729511_T_G 6 E>D No 1000Genomes
ENSVATH00254139 8 L>P No 1000Genomes
tmp_2_12729435_G_T 32 Q>K No 1000Genomes
tmp_2_12729431_T_C 33 E>G No 1000Genomes
ENSVATH01925340 36 E>K No 1000Genomes
ENSVATH01925339 44 L>F No 1000Genomes
tmp_2_12729390_C_A 47 E>* No 1000Genomes
tmp_2_12729387_G_A 48 L>F No 1000Genomes
tmp_2_12729384_T_G 49 I>L No 1000Genomes
tmp_2_12729359_G_A 57 P>L No 1000Genomes
ENSVATH01925338 60 Y>D No 1000Genomes
ENSVATH13471713 75 I>S No 1000Genomes
ENSVATH00254138 79 K>E No 1000Genomes
ENSVATH13471712 83 T>S No 1000Genomes
ENSVATH05626498 88 G>S No 1000Genomes
ENSVATH05626496 92 P>L No 1000Genomes
ENSVATH05626497 92 P>S No 1000Genomes
ENSVATH14570355 107 W>* No 1000Genomes
tmp_2_12729195_A_G 112 W>R No 1000Genomes
ENSVATH00254137 125 L>I No 1000Genomes
ENSVATH05626494 126 P>L No 1000Genomes
tmp_2_12729150_T_G 127 T>P No 1000Genomes
tmp_2_12729147_C_T 128 V>M No 1000Genomes
tmp_2_12729141_G_A 130 L>F No 1000Genomes
tmp_2_12729140_A_G 130 L>P No 1000Genomes
ENSVATH00254136 132 A>E No 1000Genomes
tmp_2_12729116_C_T 138 G>E No 1000Genomes
tmp_2_12729090_T_A
tmp_2_12729089_G_C
147 T>S No 1000Genomes
tmp_2_12729084_C_G 149 G>R No 1000Genomes
ENSVATH00254135 153 H>P No 1000Genomes
tmp_2_12729062_G_T 156 T>N No 1000Genomes
ENSVATH14570313 161 D>N No 1000Genomes
tmp_2_12729041_C_T 163 R>K No 1000Genomes
ENSVATH13471709 164 N>I No 1000Genomes
ENSVATH13471710 164 N>Y No 1000Genomes
ENSVATH13471707 168 N>K No 1000Genomes
tmp_2_12729023_T_C 169 Y>C No 1000Genomes
ENSVATH01925335 178 Y>C No 1000Genomes
ENSVATH14570312 184 E>V No 1000Genomes
tmp_2_12728960_T_G 190 Y>S No 1000Genomes
ENSVATH14570311 207 N>D No 1000Genomes
tmp_2_12728898_C_G 211 E>Q No 1000Genomes
tmp_2_12728867_G_C 221 P>R No 1000Genomes
tmp_2_12728868_G_A 221 P>S No 1000Genomes
ENSVATH01925333 222 N>S No 1000Genomes
ENSVATH13471705 236 M>I No 1000Genomes
tmp_2_12728813_C_T 239 R>K No 1000Genomes
tmp_2_12728812_C_A 239 R>S No 1000Genomes
tmp_2_12728805_C_T 242 A>T No 1000Genomes
tmp_2_12728804_G_A 242 A>V No 1000Genomes
tmp_2_12728791_C_T 246 W>* No 1000Genomes
tmp_2_12728790_C_G 247 G>R No 1000Genomes
tmp_2_12728775_T_C 252 K>E No 1000Genomes
ENSVATH01925332 254 V>I No 1000Genomes
ENSVATH13471703 255 Q>E No 1000Genomes
tmp_2_12728754_G_C 259 Q>E No 1000Genomes
tmp_2_12728744_C_T 262 G>D No 1000Genomes
tmp_2_12728741_A_T 263 V>D No 1000Genomes
tmp_2_12728738_G_C 264 A>G No 1000Genomes
tmp_2_12728726_G_A 268 T>M No 1000Genomes
tmp_2_12728670_C_T 287 V>I No 1000Genomes
tmp_2_12728657_C_T 291 C>Y No 1000Genomes
tmp_2_12728655_A_C 292 S>A No 1000Genomes
tmp_2_12728654_G_A 292 S>F No 1000Genomes
tmp_2_12728648_C_T 294 G>E No 1000Genomes
ENSVATH13471696 311 M>T No 1000Genomes
ENSVATH00254133 318 L>V No 1000Genomes
tmp_2_12728515_A_C 338 C>W No 1000Genomes
tmp_2_12728516_C_T 338 C>Y No 1000Genomes
tmp_2_12728505_A_T 342 F>I No 1000Genomes
ENSVATH05626491 357 G>R No 1000Genomes
tmp_2_12728456_C_T 358 G>D No 1000Genomes
tmp_2_12728457_C_T 358 G>S No 1000Genomes
ENSVATH14570309 362 G>E No 1000Genomes
tmp_2_12728417_A_C 371 F>C No 1000Genomes
tmp_2_12728412_C_T 373 D>N No 1000Genomes
tmp_2_12728406_T_C 375 M>V No 1000Genomes
ENSVATH05626490 381 R>W No 1000Genomes
tmp_2_12728373_C_T 386 V>I No 1000Genomes

No associated diseases with O82374

2 regional properties for O82374

Type Name Position InterPro Accession
domain F-box domain 38 - 84 IPR001810
repeat Kelch repeat type 1 131 - 224 IPR006652

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
B1WBU4 Zbtb8a Zinc finger and BTB domain-containing protein 8A Rattus norvegicus (Rat) PR
O82376 At2g29800 Putative F-box/kelch-repeat protein At2g29800 Arabidopsis thaliana (Mouse-ear cress) PR
P0C2F7 At1g19470 Kelch repeat-containing protein At1g19470 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PE09 At4g39753 F-box/kelch-repeat protein At4g39753 Arabidopsis thaliana (Mouse-ear cress) PR
Q1PF20 At2g22050 F-box/kelch-repeat protein At2g22050 Arabidopsis thaliana (Mouse-ear cress) PR
Q6P882 zbtb8a.2 Zinc finger and BTB domain-containing protein 8A.2 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MVVLHEILDG PNGDDPNNNP QEGEDNQNEN PQEEVENLRN LLELPEELIE RLIAHIPRCY
70 80 90 100 110 120
YPYISLVSRD FRQVITSDKL FRTRSLLGFN EPVLYALIGS TQTPLSWFFL RWSNFPLELH
130 140 150 160 170 180
RIRSLPTVLL GAAVVTIGYK MYVMGGTIGL NHHVSTVIVI DCRNHTWNYL PDMKRARYRA
190 200 210 220 230 240
AAGEIGGRIY VIGGRKKQDA DWVEVFNATT ESWETVSSVC PNDASANGVF STYVVMQGRI
250 260 270 280 290 300
FALDRWGCFA YKPVQGLWQS WGVASELTRF WHPLSSFTVI GELLYTVDLT CSLGHPIVVY
310 320 330 340 350 360
YPNESVWRPV MGFHLPILSQ CWSKIANFGG KLVIFCTCLG TFKHILCIVI ALEARQGGHI
370 380
WGVVESNSRV FRDDMMLPYI RLCQTVTF