Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O80961

Entry ID Method Resolution Chain Position Source
AF-O80961-F1 Predicted AlphaFoldDB

15 variants for O80961

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05682676 83 P>S No 1000Genomes
ENSVATH05682674 118 D>H No 1000Genomes
ENSVATH14597921 120 N>K No 1000Genomes
tmp_2_16358929_C_T 143 V>I No 1000Genomes
ENSVATH05682660 242 K>Q No 1000Genomes
ENSVATH05682659 259 A>P No 1000Genomes
ENSVATH14597915 261 S>N No 1000Genomes
ENSVATH14597909 318 I>V No 1000Genomes
tmp_2_16357374_C_T 353 D>N No 1000Genomes
tmp_2_16356903_T_A 411 L>F No 1000Genomes
ENSVATH01967231 453 T>I No 1000Genomes
ENSVATH00265526 470 S>L No 1000Genomes
tmp_2_16356571_C_T 472 R>H No 1000Genomes
ENSVATH05682636 518 G>V No 1000Genomes
ENSVATH05682634 529 N>S No 1000Genomes

No associated diseases with O80961

No regional properties for O80961

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O80961

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
calmodulin binding Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

3 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
defense response to fungus Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
leaf senescence The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q0DC45 MLO1 MLO protein homolog 1 Oryza sativa subsp japonica (Rice) PR
O23693 MLO4 MLO-like protein 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FI00 MLO11 MLO-like protein 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB1 MLO14 MLO-like protein 14 Arabidopsis thaliana (Mouse-ear cress) PR
O49621 MLO1 MLO-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB2 MLO13 MLO-like protein 13 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB7 MLO6 MLO-like protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SXB6 MLO2 MLO-like protein 2 Arabidopsis thaliana (Mouse-ear cress) PR
O80580 MLO15 MLO-like protein 15 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAIKERSLEE TPTWAVAVVC FVLLFISIMI EYFLHFIGHW FKKKHKKALS EALEKVKAEL
70 80 90 100 110 120
MLLGFISLLL VVLQTPVSEI CIPRNIAATW HPCSNHQEIA KYGKDYIDDG RKILEDFDSN
130 140 150 160 170 180
DFYSPRRNLA TKGYDKCAEK GKVALVSAYG IHQLHIFIFV LAVFHVLYCI ITYALGKTKM
190 200 210 220 230 240
KKWKSWERET KTIEYQYAND PERFRFARDT SFGRRHLNIW SKSTFTLWIT CFFRQFFGSV
250 260 270 280 290 300
TKVDYLTLRH GFIMAHLPAG SAARFDFQKY IERSLEQDFT VVVGISPLIW CIAVLFILTN
310 320 330 340 350 360
THGWDSYLWL PFLPLIVILI VGAKLQMIIS KLGLRIQEKG DVVKGAPVVE PGDDLFWFGR
370 380 390 400 410 420
PRFILFLIHL VLFTNAFQLA FFVWSTYEFT LKNCFHHKTE DIAIRITMGV LIQVLCSYIT
430 440 450 460 470 480
LPLYALVTQM GTSMRPTIFN DRVANALKKW HHTAKKQTKH GHSGSNTPHS SRPTTPTHGM
490 500 510 520 530 540
SPVHLLHNYN NRSLDQQTSF TASPSPPRFS DYSGQGHGHQ HFFDPESQNH SYQREITDSE
550 560 570
FSNSHHPQVD MASPVREEKE IVEHVKVDLS EFTFKK