O80961
Gene name |
MLO12 (At2g39200, T16B24.16) |
Protein name |
MLO-like protein 12 |
Names |
AtMlo12, AtMlo18 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G39200 |
EC number |
|
Protein Class |
|

Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure

Activated structure

1 structures for O80961
Entry ID | Method | Resolution | Chain | Position | Source |
---|---|---|---|---|---|
AF-O80961-F1 | Predicted | AlphaFoldDB |
15 variants for O80961
Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
---|---|---|---|---|---|
ENSVATH05682676 | 83 | P>S | No | 1000Genomes | |
ENSVATH05682674 | 118 | D>H | No | 1000Genomes | |
ENSVATH14597921 | 120 | N>K | No | 1000Genomes | |
tmp_2_16358929_C_T | 143 | V>I | No | 1000Genomes | |
ENSVATH05682660 | 242 | K>Q | No | 1000Genomes | |
ENSVATH05682659 | 259 | A>P | No | 1000Genomes | |
ENSVATH14597915 | 261 | S>N | No | 1000Genomes | |
ENSVATH14597909 | 318 | I>V | No | 1000Genomes | |
tmp_2_16357374_C_T | 353 | D>N | No | 1000Genomes | |
tmp_2_16356903_T_A | 411 | L>F | No | 1000Genomes | |
ENSVATH01967231 | 453 | T>I | No | 1000Genomes | |
ENSVATH00265526 | 470 | S>L | No | 1000Genomes | |
tmp_2_16356571_C_T | 472 | R>H | No | 1000Genomes | |
ENSVATH05682636 | 518 | G>V | No | 1000Genomes | |
ENSVATH05682634 | 529 | N>S | No | 1000Genomes |
No associated diseases with O80961
No regional properties for O80961
Type | Name | Position | InterPro Accession |
---|---|---|---|
No domain, repeats, and functional sites for O80961 |
2 GO annotations of cellular component
Name | Definition |
---|---|
integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
Name | Definition |
---|---|
calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
3 GO annotations of biological process
Name | Definition |
---|---|
defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
defense response to fungus | Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. |
leaf senescence | The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place. |
9 homologous proteins in AiPD
UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
---|---|---|---|---|
Q0DC45 | MLO1 | MLO protein homolog 1 | Oryza sativa subsp japonica (Rice) | PR |
O23693 | MLO4 | MLO-like protein 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q9FI00 | MLO11 | MLO-like protein 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q94KB1 | MLO14 | MLO-like protein 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
O49621 | MLO1 | MLO-like protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q94KB2 | MLO13 | MLO-like protein 13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q94KB7 | MLO6 | MLO-like protein 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
Q9SXB6 | MLO2 | MLO-like protein 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
O80580 | MLO15 | MLO-like protein 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
10 | 20 | 30 | 40 | 50 | 60 |
MAIKERSLEE | TPTWAVAVVC | FVLLFISIMI | EYFLHFIGHW | FKKKHKKALS | EALEKVKAEL |
70 | 80 | 90 | 100 | 110 | 120 |
MLLGFISLLL | VVLQTPVSEI | CIPRNIAATW | HPCSNHQEIA | KYGKDYIDDG | RKILEDFDSN |
130 | 140 | 150 | 160 | 170 | 180 |
DFYSPRRNLA | TKGYDKCAEK | GKVALVSAYG | IHQLHIFIFV | LAVFHVLYCI | ITYALGKTKM |
190 | 200 | 210 | 220 | 230 | 240 |
KKWKSWERET | KTIEYQYAND | PERFRFARDT | SFGRRHLNIW | SKSTFTLWIT | CFFRQFFGSV |
250 | 260 | 270 | 280 | 290 | 300 |
TKVDYLTLRH | GFIMAHLPAG | SAARFDFQKY | IERSLEQDFT | VVVGISPLIW | CIAVLFILTN |
310 | 320 | 330 | 340 | 350 | 360 |
THGWDSYLWL | PFLPLIVILI | VGAKLQMIIS | KLGLRIQEKG | DVVKGAPVVE | PGDDLFWFGR |
370 | 380 | 390 | 400 | 410 | 420 |
PRFILFLIHL | VLFTNAFQLA | FFVWSTYEFT | LKNCFHHKTE | DIAIRITMGV | LIQVLCSYIT |
430 | 440 | 450 | 460 | 470 | 480 |
LPLYALVTQM | GTSMRPTIFN | DRVANALKKW | HHTAKKQTKH | GHSGSNTPHS | SRPTTPTHGM |
490 | 500 | 510 | 520 | 530 | 540 |
SPVHLLHNYN | NRSLDQQTSF | TASPSPPRFS | DYSGQGHGHQ | HFFDPESQNH | SYQREITDSE |
550 | 560 | 570 | |||
FSNSHHPQVD | MASPVREEKE | IVEHVKVDLS | EFTFKK |