O80961
Gene name |
MLO12 (At2g39200, T16B24.16) |
Protein name |
MLO-like protein 12 |
Names |
AtMlo12, AtMlo18 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G39200 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O80961
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O80961-F1 | Predicted | AlphaFoldDB |
15 variants for O80961
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05682676 | 83 | P>S | No | 1000Genomes | |
| ENSVATH05682674 | 118 | D>H | No | 1000Genomes | |
| ENSVATH14597921 | 120 | N>K | No | 1000Genomes | |
| tmp_2_16358929_C_T | 143 | V>I | No | 1000Genomes | |
| ENSVATH05682660 | 242 | K>Q | No | 1000Genomes | |
| ENSVATH05682659 | 259 | A>P | No | 1000Genomes | |
| ENSVATH14597915 | 261 | S>N | No | 1000Genomes | |
| ENSVATH14597909 | 318 | I>V | No | 1000Genomes | |
| tmp_2_16357374_C_T | 353 | D>N | No | 1000Genomes | |
| tmp_2_16356903_T_A | 411 | L>F | No | 1000Genomes | |
| ENSVATH01967231 | 453 | T>I | No | 1000Genomes | |
| ENSVATH00265526 | 470 | S>L | No | 1000Genomes | |
| tmp_2_16356571_C_T | 472 | R>H | No | 1000Genomes | |
| ENSVATH05682636 | 518 | G>V | No | 1000Genomes | |
| ENSVATH05682634 | 529 | N>S | No | 1000Genomes |
No associated diseases with O80961
No regional properties for O80961
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O80961 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
| defense response to fungus | Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. |
| leaf senescence | The last stage of leaf development during which programmed degradation of macromolecules and nutrient recycling take place. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q0DC45 | MLO1 | MLO protein homolog 1 | Oryza sativa subsp japonica (Rice) | PR |
| O23693 | MLO4 | MLO-like protein 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FI00 | MLO11 | MLO-like protein 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB1 | MLO14 | MLO-like protein 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49621 | MLO1 | MLO-like protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB2 | MLO13 | MLO-like protein 13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB7 | MLO6 | MLO-like protein 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SXB6 | MLO2 | MLO-like protein 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80580 | MLO15 | MLO-like protein 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAIKERSLEE | TPTWAVAVVC | FVLLFISIMI | EYFLHFIGHW | FKKKHKKALS | EALEKVKAEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MLLGFISLLL | VVLQTPVSEI | CIPRNIAATW | HPCSNHQEIA | KYGKDYIDDG | RKILEDFDSN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DFYSPRRNLA | TKGYDKCAEK | GKVALVSAYG | IHQLHIFIFV | LAVFHVLYCI | ITYALGKTKM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KKWKSWERET | KTIEYQYAND | PERFRFARDT | SFGRRHLNIW | SKSTFTLWIT | CFFRQFFGSV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TKVDYLTLRH | GFIMAHLPAG | SAARFDFQKY | IERSLEQDFT | VVVGISPLIW | CIAVLFILTN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| THGWDSYLWL | PFLPLIVILI | VGAKLQMIIS | KLGLRIQEKG | DVVKGAPVVE | PGDDLFWFGR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PRFILFLIHL | VLFTNAFQLA | FFVWSTYEFT | LKNCFHHKTE | DIAIRITMGV | LIQVLCSYIT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LPLYALVTQM | GTSMRPTIFN | DRVANALKKW | HHTAKKQTKH | GHSGSNTPHS | SRPTTPTHGM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SPVHLLHNYN | NRSLDQQTSF | TASPSPPRFS | DYSGQGHGHQ | HFFDPESQNH | SYQREITDSE |
| 550 | 560 | 570 | |||
| FSNSHHPQVD | MASPVREEKE | IVEHVKVDLS | EFTFKK |