O80792

PR
Gene name
RH33 (At2g07750, T12J2.7)
Protein name
Putative DEAD-box ATP-dependent RNA helicase 33
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G07750
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

185-394 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O80792

Entry ID Method Resolution Chain Position Source
AF-O80792-F1 Predicted AlphaFoldDB

242 variants for O80792

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH01698377 5 M>I No 1000Genomes
ENSVATH12118098 8 P>L No 1000Genomes
ENSVATH01698379 9 A>T No 1000Genomes
ENSVATH05327554 11 S>F No 1000Genomes
tmp_2_3576513_T_C 11 S>P No 1000Genomes
ENSVATH12118099 14 V>M No 1000Genomes
tmp_2_3576543_C_T 21 P>S No 1000Genomes
ENSVATH12118101 23 G>S No 1000Genomes
ENSVATH12118102 23 G>V No 1000Genomes
ENSVATH12118103 29 C>S No 1000Genomes
ENSVATH05327557 36 S>F No 1000Genomes
ENSVATH05327558 37 F>Y No 1000Genomes
ENSVATH05327560 41 P>L No 1000Genomes
ENSVATH05327560 41 P>R No 1000Genomes
ENSVATH12118104 42 A>S No 1000Genomes
ENSVATH05327561 43 R>H No 1000Genomes
ENSVATH05327562 44 R>L No 1000Genomes
ENSVATH05327562 44 R>P No 1000Genomes
ENSVATH01698381 45 Q>* No 1000Genomes
tmp_2_3576625_C_T 48 P>L No 1000Genomes
ENSVATH01698382 52 L>I No 1000Genomes
ENSVATH05327563 54 H>L No 1000Genomes
ENSVATH12118305 56 G>W No 1000Genomes
ENSVATH01698401 57 L>P No 1000Genomes
ENSVATH14141288 58 S>N No 1000Genomes
tmp_2_3577298_G_A 60 R>H No 1000Genomes
ENSVATH01698402 61 I>T No 1000Genomes
ENSVATH12118722 63 S>F No 1000Genomes
ENSVATH01698404 64 E>K No 1000Genomes
ENSVATH12118723 66 S>F No 1000Genomes
ENSVATH01698405 68 W>C No 1000Genomes
ENSVATH05327593 70 R>Q No 1000Genomes
tmp_2_3577358_C_T,A 80 P>L No 1000Genomes
tmp_2_3577358_C_T,A 80 P>Q No 1000Genomes
tmp_2_3577372_G_A 85 G>R No 1000Genomes
ENSVATH12118786 88 N>K No 1000Genomes
ENSVATH14141290 91 Q>H No 1000Genomes
tmp_2_3577408_G_A 97 E>K No 1000Genomes
tmp_2_3577418_C_G 100 A>G No 1000Genomes
tmp_2_3577434_C_A 105 N>K No 1000Genomes
tmp_2_3577438_C_T 107 L>F No 1000Genomes
ENSVATH12118787 113 Q>K No 1000Genomes
tmp_2_3577457_A_T 113 Q>L No 1000Genomes
tmp_2_3577465_G_A 116 E>K No 1000Genomes
ENSVATH05327597 118 R>P No 1000Genomes
ENSVATH12118789 126 K>I No 1000Genomes
ENSVATH01698409 130 H>N No 1000Genomes
ENSVATH12118790 130 H>P No 1000Genomes
ENSVATH00216085 131 P>Q No 1000Genomes
ENSVATH12118791 134 G>A No 1000Genomes
tmp_2_3577519_G_A 134 G>S No 1000Genomes
ENSVATH05327600 135 E>V No 1000Genomes
ENSVATH05327601 137 T>M No 1000Genomes
ENSVATH05327601 137 T>R No 1000Genomes
ENSVATH01698410 138 A>T No 1000Genomes
ENSVATH01698412 140 L>S No 1000Genomes
ENSVATH05327603 142 Q>* No 1000Genomes
ENSVATH14141291 144 H>R No 1000Genomes
tmp_2_3577552_G_A 145 G>R No 1000Genomes
tmp_2_3577559_T_C 147 M>T No 1000Genomes
ENSVATH05327604 149 P>S No 1000Genomes
ENSVATH14141292 158 D>H No 1000Genomes
tmp_2_3577595_G_A 159 R>Q No 1000Genomes
ENSVATH05327605 161 M>I No 1000Genomes
ENSVATH12118935 162 K>N No 1000Genomes
tmp_2_3577625_G_C 169 W>S No 1000Genomes
tmp_2_3577627_A_G 170 N>D No 1000Genomes
tmp_2_3577632_T_G 171 D>E No 1000Genomes
tmp_2_3577636_G_A 173 D>N No 1000Genomes
ENSVATH14141294 175 P>L No 1000Genomes
tmp_2_3577652_A_T 178 K>I No 1000Genomes
ENSVATH01698415 184 R>* No 1000Genomes
ENSVATH05327608 187 S>W No 1000Genomes
ENSVATH01698416 188 D>N No 1000Genomes
ENSVATH01698418 192 S>F No 1000Genomes
ENSVATH05327609 193 T>I No 1000Genomes
ENSVATH05327610 194 P>L No 1000Genomes
ENSVATH01698420 200 L>F No 1000Genomes
ENSVATH05327611 202 S>F No 1000Genomes
ENSVATH14141336 204 T>A No 1000Genomes
ENSVATH01698422 204 T>K No 1000Genomes
tmp_2_3577733_G_A 205 C>Y No 1000Genomes
ENSVATH00216087 207 S>A No 1000Genomes
ENSVATH05327612 207 S>L No 1000Genomes
tmp_2_3577761_G_T,C 214 L>F No 1000Genomes
ENSVATH05327614 215 D>Y No 1000Genomes
tmp_2_3577768_A_G 217 S>G No 1000Genomes
ENSVATH12118936 218 R>T No 1000Genomes
ENSVATH12118937 220 G>A No 1000Genomes
ENSVATH05327615 224 M>I No 1000Genomes
ENSVATH05327616 230 N>Y No 1000Genomes
tmp_2_3577819_T_G 234 C>G No 1000Genomes
ENSVATH05327618 237 G>E No 1000Genomes
ENSVATH05327619 239 D>E No 1000Genomes
ENSVATH01698424 240 V>F No 1000Genomes
tmp_2_3577847_A_C 243 K>T No 1000Genomes
tmp_2_3577865_G_T 249 S>I No 1000Genomes
ENSVATH05327620 251 F>Y No 1000Genomes
ENSVATH01698425 253 P>S No 1000Genomes
tmp_2_3577880_A_G 254 K>R No 1000Genomes
tmp_2_3577882_T_A 255 F>I No 1000Genomes
tmp_2_3577885_T_C,A 256 S>P No 1000Genomes
tmp_2_3577885_T_C,A 256 S>T No 1000Genomes
ENSVATH05327621 260 E>D No 1000Genomes
ENSVATH01698426 265 S>P No 1000Genomes
ENSVATH05327622 275 K>T No 1000Genomes
ENSVATH01698428 288 S>R No 1000Genomes
ENSVATH12119076 299 N>D No 1000Genomes
ENSVATH07797012 300 E>K No 1000Genomes
ENSVATH01698429
ENSVATH12119078
 306 W>* No 1000Genomes
ENSVATH12119077 306 W>R No 1000Genomes
tmp_2_3578056_G_A 313 G>R No 1000Genomes
tmp_2_3578063_G_A 315 S>N No 1000Genomes
ENSVATH05327626 316 A>E No 1000Genomes
tmp_2_3578069_C_T 317 S>L No 1000Genomes
ENSVATH05327628 317 S>P No 1000Genomes
ENSVATH14141338 319 G>E No 1000Genomes
ENSVATH01698432 332 N>K No 1000Genomes
tmp_2_3578116_G_A 333 V>I No 1000Genomes
ENSVATH12119080 335 D>E No 1000Genomes
ENSVATH01698433 335 D>N No 1000Genomes
ENSVATH01698433 335 D>Y No 1000Genomes
tmp_2_3578125_G_A 336 E>K No 1000Genomes
tmp_2_3578131_C_G 338 L>V No 1000Genomes
tmp_2_3578141_C_T 341 P>L No 1000Genomes
ENSVATH12119081 343 D>E No 1000Genomes
tmp_2_3578155_A_G 346 R>G No 1000Genomes
ENSVATH07797013 346 R>T No 1000Genomes
tmp_2_3578162_G_C 348 R>T No 1000Genomes
tmp_2_3578164_G_A 349 E>K No 1000Genomes
ENSVATH05327631 352 S>G No 1000Genomes
tmp_2_3578174_G_A 352 S>N No 1000Genomes
ENSVATH05327632 355 Q>K No 1000Genomes
ENSVATH12119082 355 Q>R No 1000Genomes
ENSVATH12119083 356 S>F No 1000Genomes
ENSVATH12119083 356 S>Y No 1000Genomes
ENSVATH01698434 361 M>R No 1000Genomes
tmp_2_3578212_C_T 365 Q>* No 1000Genomes
ENSVATH05327633 371 I>M No 1000Genomes
tmp_2_3578240_C_A 374 A>E No 1000Genomes
ENSVATH01698435 375 K>N No 1000Genomes
ENSVATH12119226 379 E>D No 1000Genomes
tmp_2_3578345_C_G 384 P>R No 1000Genomes
ENSVATH14141341 388 K>N No 1000Genomes
tmp_2_3578366_C_G 391 S>C No 1000Genomes
tmp_2_3578369_C_A 392 A>E No 1000Genomes
ENSVATH00216090 393 S>F No 1000Genomes
ENSVATH12119228 407 S>F No 1000Genomes
tmp_2_3578420_G_T 409 C>F No 1000Genomes
ENSVATH12119230 410 L>I No 1000Genomes
ENSVATH01698441 423 T>K No 1000Genomes
ENSVATH01698441 423 T>M No 1000Genomes
ENSVATH12119231 428 A>G No 1000Genomes
ENSVATH12119231 428 A>V No 1000Genomes
ENSVATH05327652 433 A>V No 1000Genomes
tmp_2_3578657_T_A 437 V>D No 1000Genomes
ENSVATH05327654 439 K>E No 1000Genomes
ENSVATH05327655 446 G>S No 1000Genomes
ENSVATH05327656 447 V>I No 1000Genomes
ENSVATH12119317 448 H>N No 1000Genomes
ENSVATH14141425 452 P>L No 1000Genomes
ENSVATH01698447 452 P>S No 1000Genomes
ENSVATH01698448 455 V>G No 1000Genomes
tmp_2_3578726_C_G 460 P>R No 1000Genomes
tmp_2_3578729_C_A 461 T>K No 1000Genomes
ENSVATH14141426 469 A>T No 1000Genomes
ENSVATH05327658 470 A>T No 1000Genomes
tmp_2_3578760_G_T 471 E>D No 1000Genomes
ENSVATH12119318 472 G>S No 1000Genomes
ENSVATH05327660 474 A>T No 1000Genomes
ENSVATH12119319 476 L>R No 1000Genomes
ENSVATH05327662 478 N>Y No 1000Genomes
tmp_2_3578784_T_G 479 H>Q No 1000Genomes
ENSVATH05327664 481 G>R No 1000Genomes
ENSVATH01698450 482 I>M No 1000Genomes
ENSVATH01698451 490 G>R No 1000Genomes
tmp_2_3578816_G_T 490 G>V No 1000Genomes
tmp_2_3578821_C_T 492 R>C No 1000Genomes
ENSVATH00216093 494 R>K No 1000Genomes
ENSVATH01698453 499 R>C No 1000Genomes
ENSVATH01698453 499 R>S No 1000Genomes
ENSVATH05327666 502 S>Y No 1000Genomes
tmp_2_3578863_C_A 506 Q>K No 1000Genomes
ENSVATH09429259 515 L>F No 1000Genomes
ENSVATH12119324 525 L>I No 1000Genomes
ENSVATH12119324 525 L>V No 1000Genomes
ENSVATH05327673 536 I>T No 1000Genomes
ENSVATH01698463 542 L>I No 1000Genomes
tmp_2_3579068_T_A 543 L>* No 1000Genomes
ENSVATH01698464 549 K>R No 1000Genomes
tmp_2_3579098_A_T 553 E>V No 1000Genomes
ENSVATH01698466 555 I>T No 1000Genomes
tmp_2_3579109_G_A 557 D>N No 1000Genomes
ENSVATH14141427 562 Q>* No 1000Genomes
ENSVATH01698467 575 E>A No 1000Genomes
ENSVATH01698467 575 E>V No 1000Genomes
tmp_2_3579261_C_T 577 R>C No 1000Genomes
ENSVATH05327683 577 R>H No 1000Genomes
ENSVATH12119635 580 S>* No 1000Genomes
tmp_2_3579297_T_A 589 S>T No 1000Genomes
tmp_2_3579308_C_A 592 D>E No 1000Genomes
ENSVATH05327684 596 L>F No 1000Genomes
ENSVATH01698476 598 C>* No 1000Genomes
tmp_2_3579330_G_A 600 E>K No 1000Genomes
tmp_2_3579341_T_G 603 D>E No 1000Genomes
tmp_2_3579340_A_T 603 D>V No 1000Genomes
tmp_2_3579342_A_C 604 K>Q No 1000Genomes
tmp_2_3579481_C_G 624 L>V No 1000Genomes
ENSVATH01698480 632 M>T No 1000Genomes
ENSVATH12119697 641 C>S No 1000Genomes
ENSVATH12119697 641 C>Y No 1000Genomes
ENSVATH01698486 656 E>K No 1000Genomes
tmp_2_3579670_A_C 660 N>H No 1000Genomes
ENSVATH01698487 660 N>K No 1000Genomes
tmp_2_3579689_C_G 666 A>G No 1000Genomes
tmp_2_3579692_G_A 667 R>K No 1000Genomes
ENSVATH12119700 672 H>R No 1000Genomes
ENSVATH01698489 675 C>R No 1000Genomes
ENSVATH12119701 677 S>T No 1000Genomes
tmp_2_3579903_G_A 709 V>I No 1000Genomes
tmp_2_3579906_G_A 710 G>S No 1000Genomes
tmp_2_3579910_T_A 711 I>K No 1000Genomes
ENSVATH12120065 715 R>I No 1000Genomes
tmp_2_3579924_G_A 716 E>K No 1000Genomes
ENSVATH01698502 717 Q>* No 1000Genomes
ENSVATH01698503 721 R>L No 1000Genomes
ENSVATH07797015 725 T>I No 1000Genomes
ENSVATH12120067 727 R>K No 1000Genomes
ENSVATH05327700 731 G>R No 1000Genomes
ENSVATH01698504 733 K>E No 1000Genomes
ENSVATH01698505 734 G>* No 1000Genomes
ENSVATH01698508 738 I>V No 1000Genomes
ENSVATH12120068 740 P>L No 1000Genomes
tmp_2_3580019_T_G 747 D>E No 1000Genomes
ENSVATH12120069 752 L>V No 1000Genomes
ENSVATH05327701 753 P>S No 1000Genomes
ENSVATH12120070 759 A>T No 1000Genomes
ENSVATH01698510 768 H>Q No 1000Genomes
tmp_2_3580080_C_T 768 H>Y No 1000Genomes
ENSVATH01698516 824 A>T No 1000Genomes
tmp_2_3580337_C_T 827 R>* No 1000Genomes
ENSVATH12120342 844 R>* No 1000Genomes

No associated diseases with O80792

4 regional properties for O80792

Type Name Position InterPro Accession
domain Helicase, C-terminal 624 - 778 IPR001650
domain DEAD/DEAH box helicase domain 399 - 578 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 394 - 608 IPR014001
domain RNA helicase, DEAD-box type, Q motif 375 - 403 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

15 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8K363 Ddx18 ATP-dependent RNA helicase DDX18 Mus musculus (Mouse) PR
Q0DBS1 Os06g0535100 Putative DEAD-box ATP-dependent RNA helicase 51 Oryza sativa subsp japonica (Rice) PR
Q9FFQ1 RH31 DEAD-box ATP-dependent RNA helicase 31 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LIH9 RH51 DEAD-box ATP-dependent RNA helicase 51 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SB89 RH27 DEAD-box ATP-dependent RNA helicase 27 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SA27 RH36 DEAD-box ATP-dependent RNA helicase 36 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FVV4 RH55 DEAD-box ATP-dependent RNA helicase 55 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CAI7 TIF4A-3 Eukaryotic initiation factor 4A-3 Arabidopsis thaliana (Mouse-ear cress) PR
O22907 RH24 DEAD-box ATP-dependent RNA helicase 24 Arabidopsis thaliana (Mouse-ear cress) PR
Q56X76 RH39 DEAD-box ATP-dependent RNA helicase 39 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GY84 RH10 DEAD-box ATP-dependent RNA helicase 10 Arabidopsis thaliana (Mouse-ear cress) PR
Q84TG1 RH57 DEAD-box ATP-dependent RNA helicase 57 Arabidopsis thaliana (Mouse-ear cress) PR
P41377 TIF4A-2 Eukaryotic initiation factor 4A-2 Arabidopsis thaliana (Mouse-ear cress) PR
P41376 EIF4A1 Eukaryotic initiation factor 4A-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8H0U8 RH42 DEAD-box ATP-dependent RNA helicase 42 Arabidopsis thaliana (Mouse-ear cress) SS
10 20 30 40 50 60
MAMAMRLPAI SRAVTEVASS PVGLRRLFCS NASRFSFLSP PARRQAEPST NLFHSGLSKR
70 80 90 100 110 120
ITSERSLWNR IFSRNMGGGP RTFPGGLNKW QWKRMHEKKA REKENKLLDQ EKQLYEARIR
130 140 150 160 170 180
TEIRAKMWGH PDSGEKTAKL KQSHGPMSPK EHIKTLADRF MKAGADDLWN DNDGPVKKFD
190 200 210 220 230 240
QGSRSCSDSI DSTPIDVRRL VSATCDSMGK HRVLDSSRRG FSSMSRFKRN ESSCDEGDDV
250 260 270 280 290 300
DAKKLDTLSP FSPKFSGTKE KVKSSTSVVG VIRNKGLFGR RKFRKNDSST EEDSDEEGNE
310 320 330 340 350 360
GKMIGWMDLR KTGSSASLGN HDIKLTKRVN RNVTDEELYP PLDINRVRED LSKKQSVDNV
370 380 390 400 410 420
MEEKQEPHDS IYSAKRFDES CISPLTLKAL SASGIVKMTR VQDATLSECL DGKDALVKAK
430 440 450 460 470 480
TGTGKSMAFL LPAIETVLKA MNSGKGVHKV APIFVLILCP TRELASQIAA EGKALLKNHD
490 500 510 520 530 540
GIGVQTLIGG TRFRLDQQRL ESEPCQILIA TPGRLLDHIE NKSGLTSRLM ALKLFIVDEA
550 560 570 580 590 600
DLLLDLGFKR DVEKIIDCLP RQRQSLLFSA TIPKEVRRVS QLVLKRDHSY IDTIGLGCVE
610 620 630 640 650 660
THDKVKQSCI VAPHESHFHL VPHLLKEHIN NMPDYKIIVF CSTGMVTSLM YTLLREMKLN
670 680 690 700 710 720
VREIHARKPQ LHRTCVSDEF KESNRLILVT SDVSARGMNY PDVTLVIQVG IPSDREQYIH
730 740 750 760 770 780
RLGRTGREGK GGKGLLLIAP WERYFLDELK DLPLEPIPAP DLDSRVKHQV DQSMAKIDTS
790 800 810 820 830 840
IKEAAYHAWL GYYNSVRETG RDKTTLAELA NRFCHSIGLE KPPALFRRTA VKMGLKGISG
IPIRK