Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O80580

Entry ID Method Resolution Chain Position Source
AF-O80580-F1 Predicted AlphaFoldDB

22 variants for O80580

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_18248300_G_C 6 T>R No 1000Genomes
ENSVATH13633523 86 L>V No 1000Genomes
ENSVATH00274143 94 T>K No 1000Genomes
ENSVATH00274142 99 A>D No 1000Genomes
ENSVATH13633522 103 L>R No 1000Genomes
tmp_2_18247809_C_G 105 D>H No 1000Genomes
ENSVATH13633521 115 G>A No 1000Genomes
ENSVATH05714174 127 D>G No 1000Genomes
ENSVATH13633519 129 C>F No 1000Genomes
ENSVATH00274141 137 I>V No 1000Genomes
tmp_2_18247249_T_G 190 D>A No 1000Genomes
ENSVATH01986144 222 V>L No 1000Genomes
ENSVATH01986144 222 V>M No 1000Genomes
tmp_2_18246333_G_T 308 L>I No 1000Genomes
ENSVATH00274135 454 T>A No 1000Genomes
ENSVATH14613638 465 P>Q No 1000Genomes
ENSVATH13633439 476 G>* No 1000Genomes
tmp_2_18245547_C_A 478 G>V No 1000Genomes
ENSVATH05714157 481 Q>* No 1000Genomes
tmp_2_18245533_T_C 483 N>D No 1000Genomes
ENSVATH13633438 485 N>S No 1000Genomes
ENSVATH00274134 489 K>I No 1000Genomes

No associated diseases with O80580

No regional properties for O80580

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O80580

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
calmodulin binding Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

2 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

16 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A4FUB7 GIN1 Gypsy retrotransposon integrase-like protein 1 Bos taurus (Bovine) PR
Q6ZNG9 KRBA2 KRAB-A domain-containing protein 2 Homo sapiens (Human) PR
Q9P2P1 NYNRIN Protein NYNRIN Homo sapiens (Human) PR
Q6R2W3 ZBED9 SCAN domain-containing protein 3 Homo sapiens (Human) PR
Q9UN19 DAPP1 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide Homo sapiens (Human) PR
Q9QXT1 Dapp1 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide Mus musculus (Mouse) PR
Q9SMP1 XTH11 Probable xyloglucan endotransglucosylase/hydrolase protein 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FK75 At5g45670 GDSL esterase/lipase At5g45670 Arabidopsis thaliana (Mouse-ear cress) PR
O49621 MLO1 MLO-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB1 MLO14 MLO-like protein 14 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FI00 MLO11 MLO-like protein 11 Arabidopsis thaliana (Mouse-ear cress) PR
O23693 MLO4 MLO-like protein 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB7 MLO6 MLO-like protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SXB6 MLO2 MLO-like protein 2 Arabidopsis thaliana (Mouse-ear cress) PR
O80961 MLO12 MLO-like protein 12 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB2 MLO13 MLO-like protein 13 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAGGGTTLEY TPTWVVALVC SVIVSISFAV ERLIHRAGKH FKNNDQKQLF GALQKIKEEL
70 80 90 100 110 120
MLVGFISLLL SVGQSKIAKI CISKELSEKF LPCTKPAGAE KSLKDSSHFQ FSFTGRHLLA
130 140 150 160 170 180
GDAPAGDYCS LKGKVPIMSL SALHELHIFI FVLAVAHIIF CLLTIVFGTM KIKQWKKWED
190 200 210 220 230 240
KVLEKDFDTD QSIKKFTHVQ EHEFIRSRFL GVGKADASLG WVQSFMKQFL ASVNESDYIT
250 260 270 280 290 300
MRLGFVTTHC KTNPKFNFHK YLMRALNSDF KKVVGISWYL WVFVVLFLLL NIVAWHVYFW
310 320 330 340 350 360
LAFIPLILLL AVGTKLEHII TDLAHEVAEK HIAVEGDLVV RPSDDLFWFQ SPRLVLFLIH
370 380 390 400 410 420
FILFQNSFEI AYFFFILFQF GWDSCIMDHV KFVIPRLVIG VIIQLLCSYS TLPLYALVTQ
430 440 450 460 470 480
MGSSFKGAIF NEQTQEHLVG WAKMAKRGVK KGATQVGTSH DATSPRPSIQ LNSLLGKGSS
490
QQNQNPKEKS EIAHHD