Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O64789

Entry ID Method Resolution Chain Position Source
AF-O64789-F1 Predicted AlphaFoldDB

No variants for O64789

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O64789

No associated diseases with O64789

2 regional properties for O64789

Type Name Position InterPro Accession
repeat Leucine-rich repeat 547 - 606 IPR001611
domain NB-ARC 158 - 399 IPR002182

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ADP binding Binding to ADP, adenosine 5'-diphosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

20 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
F1MHT9 NLRC4 NLR family CARD domain-containing protein 4 Bos taurus (Bovine) SS
O14727 APAF1 Apoptotic protease-activating factor 1 Homo sapiens (Human) EV
Q9NPP4 NLRC4 NLR family CARD domain-containing protein 4 Homo sapiens (Human) SS
Q3UP24 Nlrc4 NLR family CARD domain-containing protein 4 Mus musculus (Mouse) EV
F1M649 Nlrc4 NLR family CARD domain-containing protein 4 Rattus norvegicus (Rat) SS
O22727 At1g61190 Probable disease resistance protein At1g61190 Arabidopsis thaliana (Mouse-ear cress) PR
O64790 At1g61300 Probable disease resistance protein At1g61300 Arabidopsis thaliana (Mouse-ear cress) PR
O64973 RPS5 Disease resistance protein RPS5 Arabidopsis thaliana (Mouse-ear cress) PR
P0C8S1 RPP8L2 Probable disease resistance RPP8-like protein 2 Arabidopsis thaliana (Mouse-ear cress) PR
P60838 SUMM2 Disease resistance protein SUMM2 Arabidopsis thaliana (Mouse-ear cress) PR
Q38834 RPP13L4 Disease resistance RPP13-like protein 4 Arabidopsis thaliana (Mouse-ear cress) PR
Q39214 RPM1 Disease resistance protein RPM1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8W3K3 At1g58400 Putative disease resistance protein At1g58400 Arabidopsis thaliana (Mouse-ear cress) PR
Q940K0 UNI Disease resistance protein UNI Arabidopsis thaliana (Mouse-ear cress) PR
Q9C646 RXW24L Probable disease resistance protein RXW24L Arabidopsis thaliana (Mouse-ear cress) PR
Q9FJB5 RPP8L3 Disease resistance RPP8-like protein 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LRR4 RPPL1 Putative disease resistance RPP13-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9T048 At4g27190 Disease resistance protein At4g27190 Arabidopsis thaliana (Mouse-ear cress) PR
Q9XIF0 At1g59780 Putative disease resistance protein At1g59780 Arabidopsis thaliana (Mouse-ear cress) PR
Q9I9H8 apaf1 Apoptotic protease-activating factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) SS
10 20 30 40 50 60
MGSCFSFQIA VGDQTMNRIF DCLIGKSYIR TLEKNLRALQ REMEDLRATQ HEVQNKVARE
70 80 90 100 110 120
ESRHQQRLEA VQVWLDRVNS IDIECKDLLS VSPVELQKLC LCGLCTKYVC SSYKYGKKVF
130 140 150 160 170 180
LLLEEVKILK SEGNFDEVSQ PPPRSEVEER PTQPTIGQEE MLEKAWNRLM EDGVGIMGLH
190 200 210 220 230 240
GMGGVGKTTL FKKIHNKFAE IGGTFDIVIW IVVSQGAKLS KLQEDIAEKL HLCDDLWKNK
250 260 270 280 290 300
NESDKATDIH RVLKGKRFVL MLDDIWEKVD LEAIGIPYPS EVNKCKVAFT TRSREVCGEM
310 320 330 340 350 360
GDHKPMQVNC LEPEDAWELF KNKVGDNTLS SDPVIVGLAR EVAQKCRGLP LALNVIGETM
370 380 390 400 410 420
ASKTMVQEWE YAIDVLTRSA AEFSGMENKI LPILKYSYDS LGDEHIKSCF LYCALFPEDG
430 440 450 460 470 480
QIYTETLIDK LICEGFIGED QVIKRARNKG YAMLGTLTRA NLLTKVGTEL ANLLTKVSIY
490 500 510 520 530 540
HCVMHDVVRE MALWIASDFG KQKENFVVQA SAGLHEIPEV KDWGAVRRMS LMRNEIEEIT
550 560 570 580 590 600
CESKCSELTT LFLQSNQLKN LSGEFIRYMQ KLVVLDLSDN RDFNELPEQI SGLVSLQYLD
610 620 630 640 650 660
LSFTRIEQLP VGLKELKKLT FLDLAYTARL CSISGISRLL SLRVLSLLGS KVHGDASVLK
670 680 690 700 710 720
ELQQLENLQD LAITLSAELI SLDQRLAKVI SILGIEGFLQ KPFDLSFLAS MENLSSLWVK
730 740 750 760 770 780
NSYFSEIKCR ESETDSSYLH INPKIPCFTN LSRLDIVKCH SMKDLTWILF APNLVVLFIE
790 800 810 820 830 840
DSREVGEIIN KEKATNLTSI TPFLKLERLI LCYLPKLESI YWSPLPFPLL LNIDVEECPK
850 860 870 880 890 900
LRKLPLNATS APKVEEFRIL MYPPELEWED EDTKNRFLPE MVSTSTSSKD PLLRNGIPRC
910 920
LKSESTLLLL ILLYLSSCRA FGLYN