O64468
Gene name |
At2g19050 (T20K24.6) |
Protein name |
GDSL esterase/lipase At2g19050 |
Names |
Extracellular lipase At2g19050 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G19050 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O64468
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O64468-F1 | Predicted | AlphaFoldDB |
58 variants for O64468
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05530371 | 6 | F>V | No | 1000Genomes | |
| ENSVATH05530372 | 7 | K>I | No | 1000Genomes | |
| ENSVATH13273926 | 9 | L>F | No | 1000Genomes | |
| ENSVATH01841732 | 13 | I>F | No | 1000Genomes | |
| ENSVATH13273927 | 13 | I>T | No | 1000Genomes | |
| ENSVATH01841733 | 15 | T>S | No | 1000Genomes | |
| ENSVATH01841734 | 27 | Q>P | No | 1000Genomes | |
| tmp_2_8253507_G_A | 31 | C>Y | No | 1000Genomes | |
| tmp_2_8253511_T_A | 32 | Y>* | No | 1000Genomes | |
| tmp_2_8253510_A_T | 32 | Y>F | No | 1000Genomes | |
| tmp_2_8253522_G_T | 36 | G>V | No | 1000Genomes | |
| ENSVATH05530374 | 47 | V>L | No | 1000Genomes | |
| ENSVATH05530376 | 49 | N>K | No | 1000Genomes | |
| tmp_2_8253611_G_A | 66 | G>S | No | 1000Genomes | |
| tmp_2_8253621_G_C | 69 | G>A | No | 1000Genomes | |
| ENSVATH05530386 | 93 | P>L | No | 1000Genomes | |
| tmp_2_8254181_T_A | 94 | F>I | No | 1000Genomes | |
| tmp_2_8254256_A_G | 119 | T>A | No | 1000Genomes | |
| tmp_2_8254470_A_T | 125 | E>D | No | 1000Genomes | |
| tmp_2_8254477_A_G | 128 | S>G | No | 1000Genomes | |
| tmp_2_8254505_G_T | 137 | R>L | No | 1000Genomes | |
| ENSVATH01841760 | 138 | S>A | No | 1000Genomes | |
| tmp_2_8254508_C_G | 138 | S>W | No | 1000Genomes | |
| ENSVATH13273967 | 144 | K>N | No | 1000Genomes | |
| ENSVATH01841761 | 147 | E>D | No | 1000Genomes | |
| ENSVATH09470946 | 151 | N>K | No | 1000Genomes | |
| tmp_2_8254555_C_G | 154 | L>V | No | 1000Genomes | |
| tmp_2_8254599_T_A | 168 | Y>* | No | 1000Genomes | |
| ENSVATH05530391 | 171 | P>R | No | 1000Genomes | |
| ENSVATH01841763 | 179 | K>N | No | 1000Genomes | |
| ENSVATH05530392 | 180 | F>L | No | 1000Genomes | |
| ENSVATH01841764 | 183 | D>E | No | 1000Genomes | |
| tmp_2_8254642_G_C | 183 | D>H | No | 1000Genomes | |
| tmp_2_8254940_T_A | 211 | F>Y | No | 1000Genomes | |
| ENSVATH13273987 | 213 | V>L | No | 1000Genomes | |
| ENSVATH14518906 | 218 | C>Y | No | 1000Genomes | |
| ENSVATH00237924 | 221 | R>L | No | 1000Genomes | |
| ENSVATH05530396 | 222 | M>I | No | 1000Genomes | |
| tmp_2_8255014_G_T | 236 | V>L | No | 1000Genomes | |
| ENSVATH13273989 | 242 | P>T | No | 1000Genomes | |
| tmp_2_8255037_C_A | 243 | F>L | No | 1000Genomes | |
| ENSVATH05530398 | 259 | A>T | No | 1000Genomes | |
| ENSVATH00237925 | 260 | D>E | No | 1000Genomes | |
| tmp_2_8255099_C_T | 264 | T>I | No | 1000Genomes | |
| ENSVATH05530400 | 274 | P>T | No | 1000Genomes | |
| ENSVATH13274007 | 294 | P>T | No | 1000Genomes | |
| tmp_2_8255380_G_C | 299 | C>S | No | 1000Genomes | |
| tmp_2_8255382_G_A | 300 | A>T | No | 1000Genomes | |
| ENSVATH05530404 | 303 | E>K | No | 1000Genomes | |
| tmp_2_8255433_A_G | 317 | N>D | No | 1000Genomes | |
| ENSVATH05530407 | 321 | T>I | No | 1000Genomes | |
| ENSVATH05530407 | 321 | T>R | No | 1000Genomes | |
| ENSVATH05530408 | 322 | E>K | No | 1000Genomes | |
| tmp_2_8255457_A_G | 325 | N>D | No | 1000Genomes | |
| ENSVATH05530409 | 330 | K>R | No | 1000Genomes | |
| tmp_2_8255487_G_A | 335 | G>R | No | 1000Genomes | |
| tmp_2_8255530_T_G | 349 | L>* | No | 1000Genomes | |
| ENSVATH05530411 | 350 | L>S | No | 1000Genomes |
No associated diseases with O64468
No regional properties for O64468
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O64468 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| hydrolase activity, acting on ester bonds | Catalysis of the hydrolysis of any ester bond. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid catabolic process | The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9FK75 | At5g45670 | GDSL esterase/lipase At5g45670 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEAIFKALL | LVIATTAFAT | TEAALGQRVP | CYFVFGDSVF | DNGNNNVLNT | SAKVNYSPYG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IDFARGPTGR | FSNGRNIPDI | IAELMRFSDY | IPPFTGASPE | QAHIGINYAS | GGGGIREETS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QHLGEIISFK | KQIKNHRSMI | MTAKVPEEKL | NKCLYTINIG | SNDYLNNYFM | PAPYMTNKKF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SFDEYADSLI | RSYRSYLKSL | YVLGARKVAV | FGVSKLGCTP | RMIASHGGGN | GCAAEVNKAV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EPFNKNLKAL | VYEFNRDFAD | AKFTFVDIFS | GQSPFAFFML | GFRVTDKSCC | TVKPGEELCA |
| 310 | 320 | 330 | 340 | ||
| TNEPVCPVQR | RYVYWDNVHS | TEAANMVVAK | AAYAGLITSP | YSLSWLARL |