O49621
Gene name |
MLO1 (MLO-H1, At4g02600, T10P11.12) |
Protein name |
MLO-like protein 1 |
Names |
AtMlo1, MLO protein homolog 1, AtMlo-H1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G02600 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O49621
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O49621-F1 | Predicted | AlphaFoldDB |
32 variants for O49621
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH00455677 | 3 | H>N | No | 1000Genomes | |
| ENSVATH02624520 | 5 | G>R | No | 1000Genomes | |
| ENSVATH00455687 | 87 | N>K | No | 1000Genomes | |
| tmp_4_1144898_T_C | 88 | V>A | No | 1000Genomes | |
| ENSVATH06425735 | 98 | D>H | No | 1000Genomes | |
| ENSVATH02624541 | 101 | R>L | No | 1000Genomes | |
| ENSVATH02624541 | 101 | R>Q | No | 1000Genomes | |
| tmp_4_1144945_G_A | 104 | G>R | No | 1000Genomes | |
| tmp_4_1144991_C_A | 119 | T>N | No | 1000Genomes | |
| tmp_4_1144993_T_A | 120 | F>I | No | 1000Genomes | |
| ENSVATH06425736 | 127 | T>I | No | 1000Genomes | |
| ENSVATH06425737 | 133 | E>A | No | 1000Genomes | |
| tmp_4_1145045_T_C | 137 | V>A | No | 1000Genomes | |
| ENSVATH00455690 | 139 | V>A | No | 1000Genomes | |
| tmp_4_1145050_G_A | 139 | V>I | No | 1000Genomes | |
| tmp_4_1145063_G_A | 143 | S>N | No | 1000Genomes | |
| tmp_4_1145439_G_A | 203 | E>K | No | 1000Genomes | |
| tmp_4_1145540_A_G | 213 | H>R | No | 1000Genomes | |
| tmp_4_1145554_G_T | 218 | A>S | No | 1000Genomes | |
| tmp_4_1145908_C_A | 274 | H>N | No | 1000Genomes | |
| tmp_4_1145944_A_G | 286 | K>E | No | 1000Genomes | |
| tmp_4_1146306_G_T | 336 | A>S | No | 1000Genomes | |
| ENSVATH10540472 | 359 | D>V | No | 1000Genomes | |
| tmp_4_1146916_G_C | 447 | E>D | No | 1000Genomes | |
| tmp_4_1146993_G_A | 473 | G>E | No | 1000Genomes | |
| ENSVATH00455698 | 474 | D>N | No | 1000Genomes | |
| ENSVATH02624592 | 490 | S>P | No | 1000Genomes | |
| ENSVATH02624593 | 491 | A>D | No | 1000Genomes | |
| ENSVATH00455699 | 495 | G>R | No | 1000Genomes | |
| ENSVATH06425760 | 496 | P>H | No | 1000Genomes | |
| ENSVATH06425761 | 513 | A>E | No | 1000Genomes | |
| tmp_4_1147146_A_T | 524 | H>L | No | 1000Genomes |
No associated diseases with O49621
No regional properties for O49621
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O49621 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
| response to biotic stimulus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. |
16 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| A4FUB7 | GIN1 | Gypsy retrotransposon integrase-like protein 1 | Bos taurus (Bovine) | PR |
| Q6ZNG9 | KRBA2 | KRAB-A domain-containing protein 2 | Homo sapiens (Human) | PR |
| Q9P2P1 | NYNRIN | Protein NYNRIN | Homo sapiens (Human) | PR |
| Q6R2W3 | ZBED9 | SCAN domain-containing protein 3 | Homo sapiens (Human) | PR |
| Q9UN19 | DAPP1 | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide | Homo sapiens (Human) | PR |
| Q9QXT1 | Dapp1 | Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide | Mus musculus (Mouse) | PR |
| Q9SMP1 | XTH11 | Probable xyloglucan endotransglucosylase/hydrolase protein 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FK75 | At5g45670 | GDSL esterase/lipase At5g45670 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB1 | MLO14 | MLO-like protein 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FI00 | MLO11 | MLO-like protein 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O23693 | MLO4 | MLO-like protein 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80961 | MLO12 | MLO-like protein 12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB2 | MLO13 | MLO-like protein 13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80580 | MLO15 | MLO-like protein 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB7 | MLO6 | MLO-like protein 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SXB6 | MLO2 | MLO-like protein 2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGHGGEGMSL | EFTPTWVVAG | VCTVIVAISL | AVERLLHYFG | TVLKKKKQKP | LYEALQKVKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ELMLLGFISL | LLTVFQGLIS | KFCVKENVLM | HMLPCSLDSR | REAGASEHKN | VTAKEHFQTF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LPIVGTTRRL | LAEHAAVQVG | YCSEKGKVPL | LSLEALHHLH | IFIFVLAISH | VTFCVLTVIF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GSTRIHQWKK | WEDSIADEKF | DPETALRKRR | VTHVHNHAFI | KEHFLGIGKD | SVILGWTQSF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LKQFYDSVTK | SDYVTLRLGF | IMTHCKGNPK | LNFHKYMMRA | LEDDFKQVVG | ISWYLWIFVV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IFLLLNVNGW | HTYFWIAFIP | FALLLAVGTK | LEHVIAQLAH | EVAEKHVAIE | GDLVVKPSDE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HFWFSKPQIV | LYLIHFILFQ | NAFEIAFFFW | IWVTYGFDSC | IMGQVRYIVP | RLVIGVFIQV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LCSYSTLPLY | AIVSQMGSSF | KKAIFEENVQ | VGLVGWAQKV | KQKRDLKAAA | SNGDEGSSQA |
| 490 | 500 | 510 | 520 | ||
| GPGPDSGSGS | APAAGPGAGF | AGIQLSRVTR | NNAGDTNNEI | TPDHNN |