O35368
Gene name |
Ifi203 |
Protein name |
Interferon-activable protein 203 |
Names |
Ifi-203, Interferon-inducible protein p203 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:15950 |
EC number |
|
Protein Class |
|

Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure

Activated structure

1 structures for O35368
Entry ID | Method | Resolution | Chain | Position | Source |
---|---|---|---|---|---|
AF-O35368-F1 | Predicted | AlphaFoldDB |
No variants for O35368
Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
---|---|---|---|---|---|
No variants for O35368 |
1 associated diseases with O35368
Without disease ID
4 GO annotations of cellular component
Name | Definition |
---|---|
cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
Name | Definition |
---|---|
double-stranded DNA binding | Binding to double-stranded DNA. |
identical protein binding | Binding to an identical protein or proteins. |
2 GO annotations of biological process
Name | Definition |
---|---|
activation of innate immune response | Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species. |
cellular response to interferon-beta | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. |
3 homologous proteins in AiPD
10 | 20 | 30 | 40 | 50 | 60 |
MAEYKNIVLL | KGLENMEDYQ | FRTVKSLLRK | ELKLTKKMQE | DYDRIQLADW | MEDKFPKDAG |
70 | 80 | 90 | 100 | 110 | 120 |
LDKLIKVCEH | IKDLKDLAKK | LKTEKAKVQE | KKKGKCKTAG | KKKGQDELSS | SESLFINKES |
130 | 140 | 150 | 160 | 170 | 180 |
YKSVPSSKKK | RKQITKTEGG | KKKKLTQEQA | QLPETSGTNI | KKEEDCLQNP | HKSPPTPSSS |
190 | 200 | 210 | 220 | 230 | 240 |
SSNKAPRRGT | VPKEPSREEG | HHQGPKQVMV | LKVTEPFTYD | FEETKRMFHA | TVATETEFFR |
250 | 260 | 270 | 280 | 290 | 300 |
VKVFDTALMS | KFIPGKIIAI | SHYIGCNGFL | EIYRASCVSD | VNINPTMIIS | NTLSESAIAT |
310 | 320 | 330 | 340 | 350 | 360 |
PKISYLLSQA | KGTFVNGEFV | VFKKSERHEC | ICYGIGDDTG | KMAVVVYGRL | TNVRCEPGSK |
370 | 380 | 390 | 400 | ||
LRLVCFELTS | TKDVCLLRSV | RHSYMQVINE | GKPLNPDSVR | RNSLEPYF |