Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O23693

Entry ID Method Resolution Chain Position Source
AF-O23693-F1 Predicted AlphaFoldDB

16 variants for O23693

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10950667 31 F>C No 1000Genomes
ENSVATH10950666 40 F>V No 1000Genomes
tmp_1_3675216_C_G 79 W>C No 1000Genomes
tmp_1_3675190_G_T 88 S>Y No 1000Genomes
ENSVATH10950562 109 L>F No 1000Genomes
tmp_1_3675100_T_C 118 Q>R No 1000Genomes
ENSVATH04555152 313 L>S No 1000Genomes
tmp_1_3673077_T_C 316 T>A No 1000Genomes
ENSVATH13877874 398 R>W No 1000Genomes
tmp_1_3672502_G_C 422 Q>E No 1000Genomes
ENSVATH13877873 449 E>K No 1000Genomes
ENSVATH04555141 463 A>V No 1000Genomes
tmp_1_3672184_G_T 491 N>K No 1000Genomes
tmp_1_3672122_C_T 512 G>E No 1000Genomes
ENSVATH10950460 526 N>D No 1000Genomes
tmp_1_3672012_C_T 549 G>R No 1000Genomes

No associated diseases with O23693

No regional properties for O23693

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O23693

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
calmodulin binding Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

2 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9FI00 MLO11 MLO-like protein 11 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB1 MLO14 MLO-like protein 14 Arabidopsis thaliana (Mouse-ear cress) PR
O49621 MLO1 MLO-like protein 1 Arabidopsis thaliana (Mouse-ear cress) PR
O80961 MLO12 MLO-like protein 12 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB2 MLO13 MLO-like protein 13 Arabidopsis thaliana (Mouse-ear cress) PR
O80580 MLO15 MLO-like protein 15 Arabidopsis thaliana (Mouse-ear cress) PR
Q94KB7 MLO6 MLO-like protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SXB6 MLO2 MLO-like protein 2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEHMMKEGRS LAETPTYSVA SVVTVLVFVC FLVERAIYRF GKWLKKTRRK ALFTSLEKMK
70 80 90 100 110 120
EELMLLGLIS LLLSQSARWI SEICVNSSLF NSKFYICSEE DYGIHKKVLL EHTSSTNQSS
130 140 150 160 170 180
LPHHGIHEAS HQCGHGREPF VSYEGLEQLL RFLFVLGITH VLYSGIAIGL AMSKIYSWRK
190 200 210 220 230 240
WEAQAIIMAE SDIHAKKTKV MKRQSTFVFH HASHPWSNNR FLIWMLCFLR QFRGSIRKSD
250 260 270 280 290 300
YFALRLGFLT KHNLPFTYNF HMYMVRTMED EFHGIVGISW PLWVYAIVCI CINVHGLNMY
310 320 330 340 350 360
FWISFVPAIL VMLVGTKLEH VVSKLALEVK EQQTGTSNGA QVKPRDGLFW FGKPEILLRL
370 380 390 400 410 420
IQFIIFQNAF EMATFIWFLW GIKERSCFMK NHVMISSRLI SGVLVQFWCS YGTVPLNVIV
430 440 450 460 470 480
TQMGSRHKKA VIAESVRDSL HSWCKRVKER SKHTRSVCSL DTATIDERDE MTVGTLSRSS
490 500 510 520 530 540
SMTSLNQITI NSIDQAESIF GAAASSSSPQ DGYTSRVEEY LSETYNNIGS IPPLNDEIEI
550 560 570
EIEGEEDNGG RGSGSDENNG DAGETLLELF RRT