Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O23317

Entry ID Method Resolution Chain Position Source
AF-O23317-F1 Predicted AlphaFoldDB

No variants for O23317

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O23317

No associated diseases with O23317

4 regional properties for O23317

Type Name Position InterPro Accession
domain Helicase, C-terminal 247 - 408 IPR001650
domain DEAD/DEAH box helicase domain 60 - 222 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 54 - 251 IPR014001
domain RNA helicase, DEAD-box type, Q motif 35 - 63 IPR014014

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ADP binding Binding to ADP, adenosine 5'-diphosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
F1MHT9 NLRC4 NLR family CARD domain-containing protein 4 Bos taurus (Bovine) SS
Q9NPP4 NLRC4 NLR family CARD domain-containing protein 4 Homo sapiens (Human) SS
Q3UP24 Nlrc4 NLR family CARD domain-containing protein 4 Mus musculus (Mouse) EV
F1M649 Nlrc4 NLR family CARD domain-containing protein 4 Rattus norvegicus (Rat) SS
10 20 30 40 50 60
MALTKLRFVN QFSQWLCVRK GYIHSLPENL AALQKAIEVL KTKHDDVKRR VDKEEFLGRR
70 80 90 100 110 120
HRLSQVQVEI ERLCFCGFCS KSFGKSYHYG KMVSVMLKEV ENLSSRGVFD VVTEENLVAQ
130 140 150 160 170 180
VEEMPIQSTV VGQETMLERV WNTLMKDGFK IMGLYGMGGV GKTTLLTQIN KKFSETDGGF
190 200 210 220 230 240
DIVMWVVVSK TSEIYRIQED IAKRLGLTGE EWDKKNENKR AVDIHNVLRR HKFVLLLDDI
250 260 270 280 290 300
WEKVNLELVG VPYPSRENGS IVAFTTRSRD VCGRMGVDDP MQVSCLEPED AWDLFQNKVG
310 320 330 340 350 360
ENTLKSHPDI PELAKQVAEK CRGLPLALNV IGETMACKST VQEWRHAIDE EWKKTEVKMH
370 380 390 400 410 420
DVVREMALWI SSDLGKHKDQ CIVRAGVGLH AVPEVKNWRA VRRMSLMKNE LEKILGCPTC
430 440 450 460 470 480
PQLTTLLLQK NHKLVNISGE FFRFMPNLVV LDLSWNSSLT GLPKKISEVE TTNTSEFGVH
490 500 510 520 530 540
EEFGEYAGVS KLLSLKTLRL QKSKKALDVN SAKELQLLEH IEVLTIDIFS KVEEESFKIL
550 560 570 580 590 600
TFPSMCNIRR IGIWKCGMKE IKVEMRTSSC FSSLSKVVIG QCDGLKELTW LLFAPNLTYL
610 620 630 640 650 660
DARFAEQLED IISEEKAASV TDENASIIIP FQKLECLSLS DLPKLKSIYW SPLSFPRLSE
670 680 690 700 710
LAVQEHCPKL KKLPLNSKSG TAGVELVVKY GENKWLEGVE WEDKATELRF LATCKSLYR