Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure

Activated structure

1 structures for O23317
Entry ID | Method | Resolution | Chain | Position | Source |
---|---|---|---|---|---|
AF-O23317-F1 | Predicted | AlphaFoldDB |
No variants for O23317
Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
---|---|---|---|---|---|
No variants for O23317 |
No associated diseases with O23317
4 regional properties for O23317
No GO annotations of cellular component
Name | Definition |
---|---|
No GO annotations for cellular component |
2 GO annotations of molecular function
Name | Definition |
---|---|
ADP binding | Binding to ADP, adenosine 5'-diphosphate. |
ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
Name | Definition |
---|---|
defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
4 homologous proteins in AiPD
UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
---|---|---|---|---|
F1MHT9 | NLRC4 | NLR family CARD domain-containing protein 4 | Bos taurus (Bovine) | SS |
Q9NPP4 | NLRC4 | NLR family CARD domain-containing protein 4 | Homo sapiens (Human) | SS |
Q3UP24 | Nlrc4 | NLR family CARD domain-containing protein 4 | Mus musculus (Mouse) | EV |
F1M649 | Nlrc4 | NLR family CARD domain-containing protein 4 | Rattus norvegicus (Rat) | SS |
10 | 20 | 30 | 40 | 50 | 60 |
MALTKLRFVN | QFSQWLCVRK | GYIHSLPENL | AALQKAIEVL | KTKHDDVKRR | VDKEEFLGRR |
70 | 80 | 90 | 100 | 110 | 120 |
HRLSQVQVEI | ERLCFCGFCS | KSFGKSYHYG | KMVSVMLKEV | ENLSSRGVFD | VVTEENLVAQ |
130 | 140 | 150 | 160 | 170 | 180 |
VEEMPIQSTV | VGQETMLERV | WNTLMKDGFK | IMGLYGMGGV | GKTTLLTQIN | KKFSETDGGF |
190 | 200 | 210 | 220 | 230 | 240 |
DIVMWVVVSK | TSEIYRIQED | IAKRLGLTGE | EWDKKNENKR | AVDIHNVLRR | HKFVLLLDDI |
250 | 260 | 270 | 280 | 290 | 300 |
WEKVNLELVG | VPYPSRENGS | IVAFTTRSRD | VCGRMGVDDP | MQVSCLEPED | AWDLFQNKVG |
310 | 320 | 330 | 340 | 350 | 360 |
ENTLKSHPDI | PELAKQVAEK | CRGLPLALNV | IGETMACKST | VQEWRHAIDE | EWKKTEVKMH |
370 | 380 | 390 | 400 | 410 | 420 |
DVVREMALWI | SSDLGKHKDQ | CIVRAGVGLH | AVPEVKNWRA | VRRMSLMKNE | LEKILGCPTC |
430 | 440 | 450 | 460 | 470 | 480 |
PQLTTLLLQK | NHKLVNISGE | FFRFMPNLVV | LDLSWNSSLT | GLPKKISEVE | TTNTSEFGVH |
490 | 500 | 510 | 520 | 530 | 540 |
EEFGEYAGVS | KLLSLKTLRL | QKSKKALDVN | SAKELQLLEH | IEVLTIDIFS | KVEEESFKIL |
550 | 560 | 570 | 580 | 590 | 600 |
TFPSMCNIRR | IGIWKCGMKE | IKVEMRTSSC | FSSLSKVVIG | QCDGLKELTW | LLFAPNLTYL |
610 | 620 | 630 | 640 | 650 | 660 |
DARFAEQLED | IISEEKAASV | TDENASIIIP | FQKLECLSLS | DLPKLKSIYW | SPLSFPRLSE |
670 | 680 | 690 | 700 | 710 | |
LAVQEHCPKL | KKLPLNSKSG | TAGVELVVKY | GENKWLEGVE | WEDKATELRF | LATCKSLYR |