O22907

PR
Gene name
RH24 (At2g47330, T8I13.17)
Protein name
DEAD-box ATP-dependent RNA helicase 24
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G47330
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-236 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O22907

Entry ID Method Resolution Chain Position Source
AF-O22907-F1 Predicted AlphaFoldDB

49 variants for O22907

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_19431541_G_C 26 A>G No 1000Genomes
ENSVATH05734612 27 P>L No 1000Genomes
tmp_2_19431523_A_G 32 V>A No 1000Genomes
ENSVATH05734611 36 S>F No 1000Genomes
ENSVATH05734610 49 N>I No 1000Genomes
tmp_2_19431424_C_T 65 G>D No 1000Genomes
tmp_2_19431422_C_T 66 G>S No 1000Genomes
ENSVATH13667485 66 G>V No 1000Genomes
ENSVATH14624319 87 G>R No 1000Genomes
ENSVATH05734609 89 H>Q No 1000Genomes
tmp_2_19431248_C_T 124 D>N No 1000Genomes
tmp_2_19431245_A_C 125 L>V No 1000Genomes
ENSVATH05734605 166 V>F No 1000Genomes
tmp_2_19431116_C_A 168 D>Y No 1000Genomes
ENSVATH05734604 170 R>K No 1000Genomes
tmp_2_19431104_T_C 172 I>V No 1000Genomes
tmp_2_19431076_C_T 181 S>N No 1000Genomes
tmp_2_19431053_T_A 189 N>Y No 1000Genomes
ENSVATH05734601 202 M>I No 1000Genomes
tmp_2_19430837_T_C 232 D>G No 1000Genomes
tmp_2_19430751_T_C 261 I>V No 1000Genomes
tmp_2_19430616_T_C 306 I>V No 1000Genomes
ENSVATH13667473 327 A>S No 1000Genomes
tmp_2_19430308_C_A 408 Q>H No 1000Genomes
ENSVATH13667470 431 P>S No 1000Genomes
tmp_2_19430184_C_A 450 V>F No 1000Genomes
ENSVATH05734599 458 E>D No 1000Genomes
tmp_2_19430130_G_C 468 P>A No 1000Genomes
ENSVATH05734598 472 D>N No 1000Genomes
tmp_2_19430109_C_T 475 D>N No 1000Genomes
tmp_2_19430094_C_A 480 A>S No 1000Genomes
tmp_2_19429982_T_A 517 Q>L No 1000Genomes
tmp_2_19429882_G_C 550 I>M No 1000Genomes
tmp_2_19429872_T_C 554 M>V No 1000Genomes
ENSVATH01998223 570 R>K No 1000Genomes
tmp_2_19429781_C_T 584 R>K No 1000Genomes
tmp_2_19429616_C_T 612 G>R No 1000Genomes
tmp_2_19429570_C_G 627 G>A No 1000Genomes
tmp_2_19429543_C_G 636 G>A No 1000Genomes
ENSVATH14624316 655 T>A No 1000Genomes
tmp_2_19429484_G_T 656 P>T No 1000Genomes
ENSVATH00801560 663 S>G Number of days required for the bolt height to reach 5cm [23c and 16hrs daylight. vernalized for 8 wks at 5c and 8hrs daylight] Number of days required for the bolt height to reach 5cm [23c and 16hrs daylight. vernalized for 2 wks at 5c and 8hrs daylight] [EnsemblGenome] No 1000Genomes
ENSVATH01998221 692 Q>H No 1000Genomes
tmp_2_19429348_G_C 701 P>R No 1000Genomes
ENSVATH14624315 702 S>P No 1000Genomes
tmp_2_19429318_G_C 711 T>S No 1000Genomes
tmp_2_19429307_C_T 715 D>N No 1000Genomes
ENSVATH01998220 728 P>T No 1000Genomes
ENSVATH13667469 741 H>L No 1000Genomes

No associated diseases with O22907

3 regional properties for O22907

Type Name Position InterPro Accession
conserved_site Heat shock protein 70, conserved site 11 - 18 IPR018181-1
conserved_site Heat shock protein 70, conserved site 199 - 212 IPR018181-2
conserved_site Heat shock protein 70, conserved site 336 - 350 IPR018181-3

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

13 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SA27 RH36 DEAD-box ATP-dependent RNA helicase 36 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FVV4 RH55 DEAD-box ATP-dependent RNA helicase 55 Arabidopsis thaliana (Mouse-ear cress) PR
Q9CAI7 TIF4A-3 Eukaryotic initiation factor 4A-3 Arabidopsis thaliana (Mouse-ear cress) PR
O80792 RH33 Putative DEAD-box ATP-dependent RNA helicase 33 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LIH9 RH51 DEAD-box ATP-dependent RNA helicase 51 Arabidopsis thaliana (Mouse-ear cress) PR
Q56X76 RH39 DEAD-box ATP-dependent RNA helicase 39 Arabidopsis thaliana (Mouse-ear cress) PR
Q8GY84 RH10 DEAD-box ATP-dependent RNA helicase 10 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FFQ1 RH31 DEAD-box ATP-dependent RNA helicase 31 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SB89 RH27 DEAD-box ATP-dependent RNA helicase 27 Arabidopsis thaliana (Mouse-ear cress) PR
Q84TG1 RH57 DEAD-box ATP-dependent RNA helicase 57 Arabidopsis thaliana (Mouse-ear cress) PR
P41377 TIF4A-2 Eukaryotic initiation factor 4A-2 Arabidopsis thaliana (Mouse-ear cress) PR
P41376 EIF4A1 Eukaryotic initiation factor 4A-1 Arabidopsis thaliana (Mouse-ear cress) PR
Q8H0U8 RH42 DEAD-box ATP-dependent RNA helicase 42 Arabidopsis thaliana (Mouse-ear cress) SS
10 20 30 40 50 60
MSNRKFGMEG FGINRQTSYS FERSQAPQRL YVPPSSRGGD NSEDADLDNI DYMENEEAEE
70 80 90 100 110 120
DIEEGGSAAA SGGEVDEIDP LDAFMEGIHQ EMKSAPPPKP KEKLERYKDD DDDPVESYLK
130 140 150 160 170 180
AKKDLGLTLA ADALNAGYNS DEEVYAAAKA VDAGMLDYDS DDNPIVVDKR KIEPITALDH
190 200 210 220 230 240
SSIDYEPINK DFYEELESIS GMTEQETTDY RQRLGIRVSG FDVHRPVKTF EDCGFSSQIM
250 260 270 280 290 300
SAIKKQAYEK PTAIQCQALP IVLSGRDVIG IAKTGSGKTA AFVLPMIVHI MDQPELQRDE
310 320 330 340 350 360
GPIGVICAPT RELAHQIFLE AKKFSKAYGL RVSAVYGGMS KHEQFKELKA GCEIVVATPG
370 380 390 400 410 420
RLIDMLKMKA LTMMRASYLV LDEADRMFDL GFEPQVRSIV GQIRPDRQTL LFSATMPWKV
430 440 450 460 470 480
EKLAREILSD PIRVTVGEVG MANEDITQVV NVIPSDAEKL PWLLEKLPGM IDEGDVLVFA
490 500 510 520 530 540
SKKATVDEIE AQLTLNSFKV AALHGDKDQA SRMETLQKFK SGVHHVLIAT DVAARGLDIK
550 560 570 580 590 600
SLKTVVNYDI AKDMDMHVHR IGRTGRAGDR DGVAYTLVTQ REARFAGELV NSLVAAGQNV
610 620 630 640 650 660
PPELTDLAMK DGRFKSKRDG RKGGKKGRGG GGGNKGVRGV DFGLGIGFSS ESSRTPSSKA
670 680 690 700 710 720
APSRSGAINS VRTGVMAQFK NSFVAATPSN PQNQAYPNKR PSLMGFVSGG TIGGDMGRTQ
730 740 750
SQAPPVAPTQ NASSHNSSQN HSQSSENRPR ERKRRSGWDN