O22255
Gene name |
ATL64 (At2g47560, T30B22.14) |
Protein name |
RING-H2 finger protein ATL64 |
Names |
RING-type E3 ubiquitin transferase ATL64 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G47560 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O22255
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O22255-F1 | Predicted | AlphaFoldDB |
42 variants for O22255
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13669462 | 5 | E>A | No | 1000Genomes | |
| tmp_2_19512586_A_T | 11 | I>N | No | 1000Genomes | |
| tmp_2_19512583_C_T | 12 | W>* | No | 1000Genomes | |
| ENSVATH00801743 | 19 | S>P | No | 1000Genomes | |
| ENSVATH13669461 | 28 | I>V | No | 1000Genomes | |
| ENSVATH05735856 | 33 | V>L | No | 1000Genomes | |
| ENSVATH05735855 | 44 | L>F | No | 1000Genomes | |
| ENSVATH05735854 | 45 | C>S | No | 1000Genomes | |
| tmp_2_19512469_G_C | 50 | A>G | No | 1000Genomes | |
| tmp_2_19512467_G_T | 51 | R>S | No | 1000Genomes | |
| ENSVATH13669460 | 60 | R>H | No | 1000Genomes | |
| tmp_2_19512357_G_T | 87 | D>E | No | 1000Genomes | |
| ENSVATH01999148 | 95 | S>T | No | 1000Genomes | |
| ENSVATH13669458 | 97 | K>N | No | 1000Genomes | |
| ENSVATH05735853 | 98 | N>K | No | 1000Genomes | |
| ENSVATH05735851 | 99 | P>Q | No | 1000Genomes | |
| ENSVATH05735852 | 99 | P>T | No | 1000Genomes | |
| ENSVATH13669457 | 101 | P>Q | No | 1000Genomes | |
| ENSVATH01999147 | 102 | P>S | No | 1000Genomes | |
| ENSVATH01999146 | 103 | E>K | No | 1000Genomes | |
| tmp_2_19512286_C_T | 111 | C>Y | No | 1000Genomes | |
| ENSVATH13669456 | 120 | E>D | No | 1000Genomes | |
| ENSVATH13669455 | 121 | G>R | No | 1000Genomes | |
| ENSVATH13669444 | 121 | G>V | No | 1000Genomes | |
| ENSVATH01999144 | 126 | K>N | No | 1000Genomes | |
| ENSVATH01999143 | 129 | H>Q | No | 1000Genomes | |
| ENSVATH01999142 | 133 | V>I | No | 1000Genomes | |
| ENSVATH05735848 | 141 | R>C | No | 1000Genomes | |
| ENSVATH13669442 | 150 | R>K | No | 1000Genomes | |
| ENSVATH01999138 | 157 | F>V | No | 1000Genomes | |
| ENSVATH01999137 | 163 | G>S | No | 1000Genomes | |
| ENSVATH13669441 | 164 | S>Y | No | 1000Genomes | |
| ENSVATH00801740 | 177 | G>A | No | 1000Genomes | |
| ENSVATH14625031 | 189 | I>V | No | 1000Genomes | |
| ENSVATH01999135 | 193 | S>P | No | 1000Genomes | |
| tmp_2_19512005_G_C | 205 | L>V | No | 1000Genomes | |
| tmp_2_19511996_C_A | 208 | E>* | No | 1000Genomes | |
| ENSVATH01999134 | 208 | E>V | No | 1000Genomes | |
| ENSVATH01999133 | 211 | S>A | No | 1000Genomes | |
| tmp_2_19511974_C_A | 215 | G>V | No | 1000Genomes | |
| ENSVATH01999131 | 216 | S>N | No | 1000Genomes | |
| ENSVATH13669439 | 221 | L>F | No | 1000Genomes |
No associated diseases with O22255
1 regional properties for O22255
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, RING-type | 107 - 150 | IPR001841 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
| ubiquitin protein ligase binding | Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VE61 | CG7694 | E3 ubiquitin-protein ligase RNF181 homolog | Drosophila melanogaster (Fruit fly) | PR |
| O00237 | RNF103 | E3 ubiquitin-protein ligase RNF103 | Homo sapiens (Human) | PR |
| Q86Y13 | DZIP3 | E3 ubiquitin-protein ligase DZIP3 | Homo sapiens (Human) | PR |
| Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | Homo sapiens (Human) | EV |
| Q9R1W3 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Mus musculus (Mouse) | PR |
| Q9EPZ8 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Rattus norvegicus (Rat) | PR |
| Q9ZV51 | ATL56 | RING-H2 finger protein ATL56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SKK8 | ATL22 | RING-H2 finger protein ATL22 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH02 | ATL21B | Putative RING-H2 finger protein ATL21B | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH01 | ATL21A | Putative RING-H2 finger protein ATL21A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXF8 | SGR9 | E3 ubiquitin-protein ligase SGR9, amyloplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SI09 | XERICO | Probable E3 ubiquitin-protein ligase XERICO | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYT9 | SIS3 | E3 ubiquitin-protein ligase SIS3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LGA5 | ATL31 | E3 ubiquitin-protein ligase ATL31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RXX9 | ATL6 | E3 ubiquitin-protein ligase ATL6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUZ9 | ATL63 | RING-H2 finger protein ATL63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZJ6 | ATL5 | RING-H2 finger protein ATL5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGIGEESTKP | IWGSVSHTSS | GYALNGKIML | SSVIVLFVAV | IMILCFHSYA | RWLFRRHNRR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IRRRIRSHLR | TLSASPRDQA | LDQAVLDKIP | IFVYSSKNPP | PPEEKEECSV | CLSEFEEEDE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GRLLPKCGHS | FHVDCIDTWF | RSRSTCPLCR | APVQPPFQVI | ETGSSSSSSP | LTFPTEGCER |
| 190 | 200 | 210 | 220 | ||
| EPIDLAGIIV | DISREVEFEG | SNPGLPIENG | SKFPGSRVLS | LKRLWSI |