O17930

PR
Gene name
nhr-268 (K06B4.6)
Protein name
Nuclear hormone receptor family member nhr-268
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_K06B4.6
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

40-162 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O17930

Entry ID Method Resolution Chain Position Source
AF-O17930-F1 Predicted AlphaFoldDB

No variants for O17930

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O17930

No associated diseases with O17930

2 regional properties for O17930

Type Name Position InterPro Accession
domain Nuclear hormone receptor, ligand-binding domain 98 - 337 IPR000536
domain Zinc finger, nuclear hormone receptor-type 1 - 75 IPR001628

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
zinc ion binding Binding to a zinc ion (Zn).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O17931 nhr-197 Nuclear hormone receptor family member nhr-197 Caenorhabditis elegans PR
O17928 nhr-52 Nuclear hormone receptor family member nhr-52 Caenorhabditis elegans PR
Q23489 nhr-9 Nuclear hormone receptor family member nhr-9 Caenorhabditis elegans PR
10 20 30 40 50 60
MNCLVCSARA FNRNYGVMSC FACKMFFRRT VFKNMLFNCK YFKNCTIHYK THPKCRACRF
70 80 90 100 110 120
QKCLNIGMKA ASKNDRIVSI GNYEDYNFDK LLNDLIVKND KNYSNFIDFY SLEDPSLKDI
130 140 150 160 170 180
IEDRSIMKLV RRTPETLNDV DQWSNMLAYS RISYFLDFNF IRELDSSDKN TLFKYNVSRA
190 200 210 220 230 240
GCLALAMCAY SENKPKLTFP NDVDIFPSEM YNLCGSSTAV LNQVSGQVIA KFIELEIRQE
250 260 270 280 290 300
EYLLLLLVMF CNASITNNFS HKTKLILSSH QQVYCSALFR YCQLKYSKSA PTRFTELLSV
310 320 330
FGIVNKSVNN MSFLSMMVQC YNPKFNFKRL MQDIFSHTLS