O14978
PR
Gene name |
ZNF263 |
Protein name |
Zinc finger protein 263 |
Names |
Zinc finger protein FPM315, Zinc finger protein with KRAB and SCAN domains 12 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:10127 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O14978
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O14978-F1 | Predicted | AlphaFoldDB |
617 variants for O14978
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| TCGA novel | 2 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA276925573 rs888383569 |
4 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
rs777124713 CA7860574 |
4 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777124713 CA7860575 |
4 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394495756 rs888383569 |
4 | G>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs763399679 CA7860578 |
5 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1005441851 CA276925578 |
5 | P>L | No |
ClinGen gnomAD |
|
|
rs1005441851 CA394495770 |
5 | P>R | No |
ClinGen gnomAD |
|
|
rs752169759 CA7860580 |
6 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752811374 CA394495807 |
8 | Q>L | No |
ClinGen gnomAD |
|
|
rs752811374 CA276925593 |
8 | Q>R | No |
ClinGen gnomAD |
|
|
CA276925610 rs946240439 |
9 | E>A | No |
ClinGen TOPMed |
|
|
CA7860581 rs755862314 |
9 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA276925604 rs896835906 |
9 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs763640815 CA7860582 |
10 | R>P | No |
ClinGen ExAC gnomAD |
|
|
CA394495827 rs1166947275 |
12 | G>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA276925629 rs1029408820 |
13 | L>F | No |
ClinGen Ensembl |
|
|
CA7860583 rs374352580 |
14 | L>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA7860587 rs148847911 CA7860586 |
20 | E>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA394495892 rs1453486540 |
22 | C>R | No |
ClinGen gnomAD |
|
|
rs758390607 CA394495899 |
23 | A>P | No |
ClinGen ExAC gnomAD |
|
|
CA7860588 rs758390607 |
23 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA7860589 rs368525401 |
23 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs958424813 CA276925674 |
24 | W>G | No |
ClinGen gnomAD |
|
|
rs1341952692 CA394495921 |
26 | Q>* | No |
ClinGen gnomAD |
|
|
rs747059127 CA7860590 |
26 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1339964250 CA394495927 |
27 | E>* | No |
ClinGen TOPMed |
|
| TCGA novel | 27 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA276925675 rs776718624 |
29 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860592 rs776718624 |
29 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs144448823 CA7860594 |
30 | P>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs144448823 CA7860595 |
30 | P>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA7860596 rs763489293 |
32 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394495955 rs1426197551 |
32 | D>N | No |
ClinGen gnomAD |
|
|
CA7860597 rs766866736 |
33 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860598 rs775038069 |
34 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394495977 rs1173912670 |
35 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs763594304 CA7860600 |
36 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs375990667 CA7860601 |
37 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA7860603 rs371782148 |
42 | L>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA394496049 rs1283120883 |
46 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1283120883 CA394496047 |
46 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA276925730 rs781047965 |
48 | R>G | No |
ClinGen Ensembl |
|
|
rs1274861395 CA394496075 |
50 | Q>R | No |
ClinGen TOPMed |
|
|
rs1484624775 CA394496091 |
52 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA394496094 rs1203985165 |
53 | A>P | No |
ClinGen gnomAD |
|
|
CA276925742 rs139088208 COSM107433 |
55 | P>L | skin [Cosmic] | No |
ClinGen cosmic curated Ensembl |
| TCGA novel | 55 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA394496112 rs1448301642 |
56 | R>Q | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 57 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs755040475 CA7860608 |
57 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA394496122 rs781282062 |
58 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA7860609 rs781282062 |
58 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA7860610 rs748365231 |
58 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs769970759 CA7860611 |
59 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394496144 rs1325921371 |
60 | S>N | No |
ClinGen TOPMed |
|
|
rs778176324 CA7860612 |
61 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1403400916 CA394496178 |
62 | L>P | No |
ClinGen gnomAD |
|
|
CA7860614 rs771228191 |
63 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs1596368511 CA394496203 |
64 | E>G | No |
ClinGen Ensembl |
|
|
CA276925774 rs369265980 |
67 | H>L | No |
ClinGen ESP |
|
|
CA394496268 rs1331330565 |
68 | G>E | No |
ClinGen TOPMed |
|
|
CA394496266 rs1336657843 |
68 | G>R | No |
ClinGen TOPMed |
|
|
rs1596368541 CA394496279 |
69 | W>G | No |
ClinGen Ensembl |
|
|
CA7860616 rs185197463 |
71 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1488975612 CA394496332 |
73 | E>D | No |
ClinGen gnomAD |
|
|
rs1260870203 CA394496327 |
73 | E>Q | No |
ClinGen gnomAD |
|
|
COSM1377708 rs888298098 CA276925793 |
75 | R>H | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
CA394496351 rs1307933213 |
75 | R>S | No |
ClinGen Ensembl |
|
|
rs1267689465 CA394496385 |
77 | K>R | No |
ClinGen gnomAD |
|
|
rs1490459814 CA394496400 |
78 | E>G | No |
ClinGen gnomAD |
|
|
CA394496413 rs1192655738 |
79 | Q>* | No |
ClinGen gnomAD |
|
|
COSM264919 CA394496425 rs1470710821 |
79 | Q>H | large_intestine [Cosmic] | No |
ClinGen cosmic curated TOPMed |
|
CA7860619 rs761415128 |
81 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA394496440 rs1171581606 |
81 | L>V | No |
ClinGen TOPMed |
|
|
CA7860620 rs764980014 |
82 | E>D | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 84 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1596368597 CA394496494 |
85 | V>G | No |
ClinGen Ensembl |
|
|
rs1365657390 CA394496499 |
86 | L>* | No |
ClinGen gnomAD |
|
| TCGA novel | 87 | E>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA394496509 rs1470324969 |
87 | E>D | No |
ClinGen TOPMed |
|
|
rs1422789013 CA394496503 |
87 | E>Q | No |
ClinGen gnomAD |
|
|
CA394496516 rs1163211225 |
88 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
CA276925805 rs1036913796 |
92 | I>V | No |
ClinGen Ensembl |
|
|
rs537043093 CA7860624 |
94 | P>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA394496595 rs1309753866 |
95 | Q>* | No |
ClinGen gnomAD |
|
| TCGA novel | 96 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1373611141 CA394496625 |
97 | I>F | No |
ClinGen gnomAD |
|
|
rs781167397 CA7860626 |
99 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394496669 rs1204370347 |
100 | R>K | No |
ClinGen TOPMed |
|
|
CA276925832 rs958409247 |
102 | Q>E | No |
ClinGen TOPMed |
|
|
CA7860628 rs756384881 |
104 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA276925847 rs200429663 |
107 | E>K | No |
ClinGen Ensembl |
|
|
rs749446313 CA7860630 |
111 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA7860631 rs755937940 |
112 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA394496863 rs1238484097 |
115 | L>V | No |
ClinGen TOPMed |
|
| TCGA novel | 116 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA394496881 rs1376809563 |
116 | V>G | No |
ClinGen TOPMed |
|
|
rs199893447 CA7860632 |
118 | D>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA7860633 rs199893447 |
118 | D>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA394496940 rs1177751620 |
120 | Q>P | No |
ClinGen gnomAD |
|
|
rs772606679 CA7860634 |
121 | R>* | No |
ClinGen ExAC gnomAD |
|
|
rs772606679 CA276925863 |
121 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs1455069316 CA394496971 |
122 | E>A | No |
ClinGen TOPMed |
|
|
rs372880649 CA276925875 |
122 | E>K | No |
ClinGen Ensembl |
|
|
rs761399869 CA7860636 |
123 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA394496987 rs761399869 |
123 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA7860635 rs776059444 |
123 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs1168580437 CA394496998 |
124 | G>E | No |
ClinGen TOPMed gnomAD |
|
|
rs202041463 CA7860637 |
124 | G>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs773025508 CA276925901 |
129 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs773025508 CA7860638 |
129 | Q>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394497100 rs1444227536 |
132 | N>D | No |
ClinGen gnomAD |
|
|
rs373743743 CA7860664 |
133 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs373743743 CA7860665 |
133 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860666 rs372228823 |
134 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA394497118 rs775519399 |
135 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775519399 CA7860667 |
135 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760565692 COSM1233780 CA7860668 |
136 | G>R | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
| TCGA novel | 138 | E>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs764198314 CA7860669 |
139 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764198314 CA276926663 |
139 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394497149 rs1177829902 |
140 | L>H | No |
ClinGen gnomAD |
|
|
CA276926669 rs966618850 |
140 | L>V | No |
ClinGen TOPMed |
|
|
rs753890757 CA7860670 |
142 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA276926671 rs267604536 |
143 | E>K | No |
ClinGen Ensembl |
|
|
CA7860672 rs142722524 |
144 | P>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA7860674 rs142722524 |
144 | P>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA7860673 rs142722524 |
144 | P>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs758798897 CA7860675 |
146 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs780245067 CA7860676 |
146 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs780245067 CA276926680 |
146 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs747562430 CA7860677 |
147 | L>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA394497189 rs140419803 |
148 | E>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs140419803 CA7860678 |
148 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA276926708 rs200922031 |
149 | T>R | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA7860680 rs147608270 |
151 | R>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs377570960 CA276926719 |
151 | R>L | No |
ClinGen gnomAD |
|
|
rs377570960 CA394497207 |
151 | R>Q | No |
ClinGen gnomAD |
|
|
CA394497210 rs1171925668 |
152 | E>Q | No |
ClinGen gnomAD |
|
|
rs1283728938 CA394497220 |
153 | S>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1283728938 CA394497222 |
153 | S>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1354784065 CA394497228 |
154 | P>R | No |
ClinGen TOPMed |
|
|
rs1596369289 CA394497234 |
155 | S>I | No |
ClinGen Ensembl |
|
|
CA7860683 rs774066626 |
158 | L>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs550664600 CA394497272 |
161 | M>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1567249571 CA394497275 |
161 | M>T | No |
ClinGen Ensembl |
|
|
rs550664600 CA7860684 |
161 | M>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1200526161 CA394497297 |
164 | E>G | No |
ClinGen gnomAD |
|
|
rs771932436 CA7860685 |
165 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA394497301 rs771932436 |
165 | R>G | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 165 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs775233980 CA7860686 |
166 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA394497314 rs1449677035 |
167 | P>S | No |
ClinGen TOPMed |
|
|
CA394497340 rs1183983518 |
171 | L>P | No |
ClinGen Ensembl |
|
|
rs1596369318 CA394497352 |
173 | E>K | No |
ClinGen Ensembl |
|
|
rs1419737669 CA394497361 |
174 | L>P | No |
ClinGen gnomAD |
|
|
rs945658490 CA276926759 |
177 | P>R | No |
ClinGen gnomAD |
|
|
CA394497382 rs1324045665 |
178 | S>N | No |
ClinGen gnomAD |
|
|
rs765168966 CA7860692 |
181 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs765168966 CA394497404 |
181 | R>T | No |
ClinGen ExAC gnomAD |
|
|
CA394497414 rs1278851831 |
182 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA394497412 rs1338327060 |
182 | D>G | No |
ClinGen TOPMed |
|
|
CA394497419 rs1377785379 |
183 | P>L | No |
ClinGen gnomAD |
|
|
rs1377785379 CA394497421 |
183 | P>R | No |
ClinGen gnomAD |
|
| TCGA novel | 184 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA394497430 rs1289883090 |
185 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA7860694 rs539395135 |
186 | V>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA7860695 rs766818946 |
188 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394497450 rs766818946 |
188 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394497457 rs1181763986 |
189 | R>W | No |
ClinGen gnomAD |
|
|
CA7860697 rs755610770 |
190 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA7860713 rs763297120 |
191 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA394497493 rs1167040483 |
192 | S>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA276927270 rs368902508 |
192 | S>P | No |
ClinGen ESP TOPMed |
|
|
rs1400751169 CA394497499 |
193 | A>P | No |
ClinGen gnomAD |
|
| TCGA novel | 193 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1596369716 CA394497512 |
194 | P>L | No |
ClinGen Ensembl |
|
|
CA394497509 rs1375169502 |
194 | P>S | No |
ClinGen TOPMed |
|
|
rs770138722 CA276927271 |
195 | W>* | No |
ClinGen gnomAD |
|
|
CA394497523 rs770138722 CA394497522 |
195 | W>C | No |
ClinGen gnomAD |
|
| TCGA novel | 196 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs528363608 CA7860714 |
197 | S>F | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs200446580 CA7860715 |
198 | L>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs948263417 COSM3420968 CA276927277 |
198 | L>V | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA276927295 rs1006310419 |
200 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1336421528 CA394497583 |
203 | G>R | No |
ClinGen gnomAD |
|
|
CA394497584 rs1336421528 |
203 | G>W | No |
ClinGen gnomAD |
|
|
CA394497622 rs1180453001 |
207 | D>G | No |
ClinGen TOPMed |
|
|
rs767945192 CA7860719 |
208 | K>E | No |
ClinGen ExAC TOPMed |
|
|
CA7860720 rs753278944 |
208 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs767945192 CA276927309 |
208 | K>Q | No |
ClinGen ExAC TOPMed |
|
|
rs778533259 CA7860722 |
212 | G>A | No |
ClinGen ExAC gnomAD |
|
|
rs1222271354 CA394497661 |
213 | P>T | No |
ClinGen gnomAD |
|
|
CA276927337 rs920200768 |
214 | Q>* | No |
ClinGen gnomAD |
|
|
CA7860723 rs749886081 |
214 | Q>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394497692 rs761300241 |
216 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA7860740 rs761300241 |
216 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA7860742 rs754301182 |
217 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs138244751 CA7860743 |
218 | S>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs933002985 CA276927629 |
219 | L>S | No |
ClinGen TOPMed |
|
|
CA7860744 rs765822829 |
222 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394497740 rs1366775220 |
223 | A>E | No |
ClinGen gnomAD |
|
|
CA394497737 rs1323248560 |
223 | A>T | No |
ClinGen gnomAD |
|
|
rs754607315 CA7860746 |
224 | M>I | No |
ClinGen ExAC gnomAD |
|
|
CA276927638 rs912811087 |
224 | M>T | No |
ClinGen Ensembl |
|
|
rs555378859 CA276927637 |
224 | M>V | No |
ClinGen TOPMed gnomAD |
|
|
CA394497759 rs1302996717 |
226 | I>F | No |
ClinGen gnomAD |
|
|
CA394497769 rs1368734112 |
227 | S>F | No |
ClinGen gnomAD |
|
|
CA7860748 rs143903106 |
229 | E>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs755874777 CA7860749 |
230 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1555461822 CA720073270 |
231 | W>* | No |
ClinGen TOPMed |
|
|
CA394497795 rs1180657261 |
231 | W>L | No |
ClinGen TOPMed |
|
|
rs1272479521 CA394497816 |
234 | Q>E | No |
ClinGen TOPMed |
|
| TCGA novel | 234 | Q>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs749202694 CA7860752 |
237 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs771166497 CA7860753 |
238 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA7860754 rs138724806 |
240 | A>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA394497861 rs138724806 |
240 | A>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1201263004 CA394497858 |
240 | A>T | No |
ClinGen TOPMed |
|
|
CA394497864 rs746141205 |
241 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs772410135 CA7860756 |
241 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA7860755 rs746141205 |
241 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA7860757 rs775987421 |
242 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394497874 rs1285170570 |
243 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
CA276927693 rs895333501 |
245 | T>K | No |
ClinGen TOPMed gnomAD |
|
|
rs895333501 CA394497891 |
245 | T>M | No |
ClinGen TOPMed gnomAD |
|
|
CA7860760 rs777023654 |
248 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA7860761 rs138080626 |
249 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA7860762 rs765911122 |
250 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA7860763 rs751058866 |
251 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753672721 CA7860786 |
257 | E>V | No |
ClinGen ExAC gnomAD |
|
|
CA7860788 rs778997424 |
259 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750327718 CA394498855 |
262 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750327718 CA7860789 |
262 | S>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs758427603 CA394498860 |
263 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs758427603 CA7860790 |
263 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs780139274 CA7860791 |
263 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs747230956 CA7860792 |
264 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs1466320270 CA394498876 |
265 | V>A | No |
ClinGen TOPMed |
|
|
rs781606958 CA7860794 |
266 | P>R | No |
ClinGen ExAC gnomAD |
|
|
CA7860793 rs768897973 |
266 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1596371699 CA394498895 |
269 | Q>E | No |
ClinGen Ensembl |
|
|
CA7860797 rs773732612 |
271 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs201954010 CA7860798 |
273 | G>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA394498921 rs1359226448 |
273 | G>R | No |
ClinGen gnomAD |
|
|
rs143755010 CA7860799 |
275 | K>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs775274232 CA7860800 |
276 | L>R | No |
ClinGen ExAC gnomAD |
|
|
CA394498962 rs1280029840 |
279 | P>S | No |
ClinGen gnomAD |
|
| TCGA novel | 280 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1287850833 CA394498968 |
280 | S>G | No |
ClinGen gnomAD |
|
|
rs1321246079 CA394498969 |
280 | S>N | No |
ClinGen gnomAD |
|
|
CA7860802 rs763798657 |
282 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753471818 CA7860803 |
283 | S>R | No |
ClinGen ExAC gnomAD |
|
|
rs201117200 CA7860805 |
284 | C>F | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA7860804 rs761712122 |
284 | C>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201117200 CA276929982 |
284 | C>Y | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs966505556 CA276930007 |
286 | E>D | No |
ClinGen TOPMed |
|
|
rs1196217416 CA394499026 |
289 | S>G | No |
ClinGen gnomAD |
|
|
rs1362429827 CA394499030 |
289 | S>I | No |
ClinGen TOPMed |
|
|
rs367864260 CA394499037 |
290 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs367864260 CA7860806 |
290 | P>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1267209372 CA394499035 |
290 | P>S | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 291 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA7860807 rs758321279 |
292 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751658512 CA7860809 |
293 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751658512 CA276930042 |
293 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780042699 CA7860808 |
293 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA7860810 rs148532135 |
295 | P>A | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA7860812 rs748323811 |
295 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs148532135 CA276930046 |
295 | P>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs148532135 CA7860811 |
295 | P>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA394500997 rs1210747561 |
297 | E>Q | No |
ClinGen gnomAD |
|
|
CA394501005 rs761573685 |
298 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860842 rs761573685 |
298 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA276930664 rs769553815 |
300 | F>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860843 rs769553815 |
300 | F>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772676928 CA7860844 |
302 | N>D | No |
ClinGen ExAC |
|
|
CA394501048 rs1269982428 |
303 | L>P | No |
ClinGen TOPMed |
|
|
rs117066066 CA7860845 |
303 | L>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1596372371 CA394501066 |
305 | G>A | No |
ClinGen Ensembl |
|
|
rs766043304 CA7860846 |
306 | V>F | No |
ClinGen ExAC gnomAD |
|
|
COSM380116 rs759361372 CA7860848 |
307 | P>L | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA7860847 rs142118859 |
307 | P>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs752762352 CA7860850 |
309 | V>L | No |
ClinGen ExAC |
|
|
rs220379 CA394501105 |
310 | C>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
VAR_052801 rs220379 CA7860851 |
310 | C>S | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs220379 CA7860852 |
310 | C>Y | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs753947224 CA7860853 |
311 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs1330561831 CA394501135 |
314 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1401168649 CA394501146 |
315 | H>Y | No |
ClinGen gnomAD |
|
|
rs779106798 CA394501154 |
316 | P>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779106798 CA7860856 |
316 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860855 rs757663188 |
316 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA7860857 rs746422581 |
317 | Q>H | No |
ClinGen ExAC |
|
|
CA394501171 rs1340022870 |
318 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
CA394501170 rs1340022870 |
318 | V>E | No |
ClinGen TOPMed gnomAD |
|
|
CA394501193 rs1218606859 |
321 | P>S | No |
ClinGen gnomAD |
|
|
CA394501216 rs1318026168 |
323 | Q>H | No |
ClinGen gnomAD |
|
|
rs747654211 CA7860860 |
323 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1404113277 CA394501223 |
324 | A>V | No |
ClinGen TOPMed |
|
|
CA276930765 rs139107623 |
325 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA TOPMed gnomAD |
|
CA7860864 rs79713839 |
325 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA7860863 rs79713839 |
325 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA7860862 COSM417020 rs79713839 |
325 | R>Q | urinary_tract [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
CA394501230 rs759529561 |
326 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759529561 CA7860866 |
326 | G>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394501246 rs1476697376 |
328 | V>M | No |
ClinGen gnomAD |
|
|
rs1424182628 CA394501260 |
329 | P>L | No |
ClinGen gnomAD |
|
|
rs1169909443 CA394501257 |
329 | P>S | No |
ClinGen gnomAD |
|
|
rs1169909443 CA394501255 |
329 | P>T | No |
ClinGen gnomAD |
|
|
CA394501267 rs1170957554 |
330 | W>* | No |
ClinGen gnomAD |
|
|
rs775338696 CA7860868 |
330 | W>C | No |
ClinGen ExAC gnomAD |
|
|
CA7860869 rs760755834 |
331 | S>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 332 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA394501281 rs1379730813 |
332 | P>S | No |
ClinGen TOPMed |
|
|
rs1336366973 CA394501293 |
333 | E>V | No |
ClinGen gnomAD |
|
|
rs1253104497 CA394501304 |
335 | G>R | No |
ClinGen TOPMed |
|
|
CA394501322 rs761905868 |
337 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs199591348 CA7860874 |
337 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs761905868 CA7860873 |
337 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs750738145 COSM1478857 CA7860875 |
338 | H>Y | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA394501340 rs1596372539 |
339 | D>A | No |
ClinGen Ensembl |
|
|
CA7860876 rs759038312 |
340 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs140113954 CA7860879 |
340 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs140113954 CA7860878 |
340 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs759038312 CA7860877 |
340 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs767341301 COSM1189156 CA7860880 |
341 | S>L | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA7860882 rs369921094 |
342 | Q>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA394501375 rs1222619594 |
342 | Q>R | No |
ClinGen TOPMed |
|
|
CA394501406 rs1347145720 |
344 | D>H | No |
ClinGen gnomAD |
|
|
rs745669107 CA7860884 |
346 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860886 rs775426796 |
348 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA276930820 rs267604537 |
349 | P>A | No |
ClinGen TOPMed |
|
| rs1567252485 | 349 | P>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1358793277 CA394501542 |
349 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1358793277 CA394501544 |
349 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs267604537 CA276930819 |
349 | P>S | No |
ClinGen TOPMed |
|
|
CA7860887 rs760565822 |
350 | E>K | No |
ClinGen ExAC |
|
|
CA394501565 rs760565822 |
350 | E>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA |
|
rs1385632633 CA394501593 |
351 | G>D | No |
ClinGen gnomAD |
|
|
CA394501580 rs1342747555 |
351 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1330029216 CA394501670 |
353 | M>T | No |
ClinGen gnomAD |
|
|
rs1301143166 CA394501658 |
353 | M>V | No |
ClinGen gnomAD |
|
|
rs372396655 CA7860889 |
354 | E>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs369060248 CA394501752 |
356 | A>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA7860890 rs369060248 |
356 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1160785521 CA394501781 |
357 | L>F | No |
ClinGen TOPMed |
|
|
CA394501792 rs972648023 |
358 | A>S | No |
ClinGen gnomAD |
|
|
CA276930846 rs972648023 |
358 | A>T | No |
ClinGen gnomAD |
|
|
CA394501797 rs1286530244 |
358 | A>V | No |
ClinGen gnomAD |
|
|
CA394501855 rs1486705865 |
361 | S>L | No |
ClinGen gnomAD |
|
|
rs763436625 CA394501895 |
363 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA7860892 rs373347177 |
363 | G>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs763436625 CA7860893 |
363 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA7860894 rs376586511 |
365 | E>D | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 366 | L>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA394501972 rs1378539045 |
367 | G>E | No |
ClinGen gnomAD |
|
|
CA7860896 COSM1734270 rs755524071 |
368 | R>* | Variant assessed as Somatic; 0.0 impact. pancreas [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA7860897 rs145843272 |
368 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA394502001 rs753284784 |
369 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA7860899 rs541895788 |
369 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs753284784 CA7860898 |
369 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1389027589 CA394502060 |
372 | L>V | No |
ClinGen gnomAD |
|
|
CA394502080 rs1465160274 |
373 | Q>* | No |
ClinGen TOPMed |
|
|
rs75472250 CA276930859 |
373 | Q>R | No |
ClinGen Ensembl |
|
|
rs943548715 CA276930866 |
376 | K>R | No |
ClinGen TOPMed |
|
|
CA7860901 rs745472045 |
377 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779791895 CA7860904 |
378 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860906 rs746994545 |
381 | P>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs746994545 CA394502169 |
381 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1488800306 CA394502165 |
381 | P>T | No |
ClinGen gnomAD |
|
|
CA7860907 rs768461124 |
382 | L>S | No |
ClinGen ExAC gnomAD |
|
|
rs958430077 CA276930905 |
385 | K>I | No |
ClinGen TOPMed |
|
|
CA7860908 rs776835539 |
386 | N>S | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 389 | N>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1567252725 CA394502290 |
396 | H>Y | No |
ClinGen Ensembl |
|
|
CA7860912 rs763241212 |
399 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA394502312 rs1164600994 |
399 | I>V | No |
ClinGen gnomAD |
|
|
rs770545096 CA276930915 |
402 | A>D | No |
ClinGen Ensembl |
|
|
rs760155666 CA7860915 |
403 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394502356 rs1384809795 |
406 | C>G | No |
ClinGen TOPMed |
|
|
CA394502358 rs1331625322 |
406 | C>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs200998380 CA276930923 |
407 | M>R | No |
ClinGen Ensembl |
|
|
CA394502364 rs1164372687 |
407 | M>V | No |
ClinGen TOPMed |
|
|
CA394502377 rs1374977422 |
409 | V>M | No |
ClinGen gnomAD |
|
|
rs189669184 CA7860917 |
411 | C>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1311805537 CA394502400 |
412 | T>A | No |
ClinGen gnomAD |
|
|
CA7860918 rs756739328 |
412 | T>I | No |
ClinGen ExAC gnomAD |
|
|
COSM970398 rs917438873 CA276930931 |
413 | E>K | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA7860919 rs764684677 |
414 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs750116677 CA7860920 |
415 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA7860921 rs758023508 |
416 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs371017559 CA7860922 |
420 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA7860923 rs149007034 |
420 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs371017559 CA394502448 |
420 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1181472304 CA394502460 |
422 | L>V | No |
ClinGen gnomAD |
|
|
CA394502468 rs1476366159 |
423 | S>* | No |
ClinGen gnomAD |
|
|
rs781003073 CA7860925 |
423 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs748082036 CA7860926 |
424 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA7860927 rs769807273 |
425 | H>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765822647 CA394502501 |
428 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs374333605 CA276930974 |
429 | L>Q | No |
ClinGen ESP TOPMed |
|
|
CA394502508 rs1301858327 |
430 | G>R | No |
ClinGen gnomAD |
|
|
CA394502526 rs1379652578 |
432 | E>D | No |
ClinGen gnomAD |
|
|
rs1050442564 CA276930983 |
432 | E>K | No |
ClinGen TOPMed |
|
|
CA7860930 rs771274938 |
433 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774649019 CA7860931 |
435 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA394502543 rs1339840661 |
435 | K>R | No |
ClinGen gnomAD |
|
| TCGA novel | 437 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs759833600 CA7860932 |
438 | E>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 442 | C>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA276930997 rs910666389 |
444 | S>R | No |
ClinGen TOPMed |
|
|
rs944775366 CA276931001 |
445 | Q>L | No |
ClinGen TOPMed |
|
|
rs1596372924 CA394502628 |
447 | T>P | No |
ClinGen Ensembl |
|
|
COSM1271204 CA7860937 rs749918009 |
451 | R>C | oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA276931012 rs758109552 |
451 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA7860938 rs758109552 |
451 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs1363167808 CA394502674 |
454 | R>C | No |
ClinGen TOPMed |
|
|
rs1421068204 CA394502675 COSM1271203 |
454 | R>H | oesophagus [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1363167808 CA394502672 |
454 | R>S | No |
ClinGen TOPMed |
|
| TCGA novel | 455 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs754763420 CA7860941 |
457 | T>M | No |
ClinGen ExAC gnomAD |
|
|
rs1359634373 CA394502732 |
462 | Y>* | No |
ClinGen gnomAD |
|
|
CA394502736 rs1400574955 |
463 | Q>P | No |
ClinGen gnomAD |
|
|
CA394502754 rs1596372983 |
465 | N>S | No |
ClinGen Ensembl |
|
|
rs1596372990 CA394502758 |
466 | I>F | No |
ClinGen Ensembl |
|
|
CA394502767 rs1271815088 |
467 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA394502773 rs371748967 |
468 | G>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA7860944 rs371748967 |
468 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA394502787 rs1302249257 |
470 | C>G | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 470 | C>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA7860945 rs778065733 |
472 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA276931053 rs1047461644 |
473 | C>Y | No |
ClinGen TOPMed |
|
|
rs749384534 CA7860946 |
474 | N>H | No |
ClinGen ExAC gnomAD |
|
|
rs1488799040 CA394502823 |
475 | S>C | No |
ClinGen gnomAD |
|
| TCGA novel | 475 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA276931058 rs79252552 |
475 | S>P | No |
ClinGen Ensembl |
|
|
CA394502822 rs1488799040 |
475 | S>Y | No |
ClinGen gnomAD |
|
|
CA394502829 rs1275337657 |
476 | N>K | No |
ClinGen TOPMed |
|
|
rs374659542 CA7860948 |
476 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA276931070 rs374659542 |
476 | N>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA7860950 rs772361260 |
479 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs1190200369 CA394502846 |
479 | R>K | No |
ClinGen gnomAD |
|
|
rs1395151742 CA394502852 |
480 | H>Y | No |
ClinGen gnomAD |
|
|
CA7860951 rs372353619 |
481 | Q>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA394502868 rs1156422694 |
482 | R>K | No |
ClinGen gnomAD |
|
|
rs761143319 CA7860952 |
483 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA394502890 rs1307835871 |
485 | T>S | No |
ClinGen TOPMed gnomAD |
|
|
CA7860955 rs762460909 |
486 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA394502893 rs762460909 |
486 | G>W | No |
ClinGen ExAC gnomAD |
|
|
rs1435668881 CA394502897 |
487 | E>K | No |
ClinGen gnomAD |
|
|
rs765824769 CA7860956 |
489 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA394502922 rs1373249336 |
490 | Y>C | No |
ClinGen gnomAD |
|
| TCGA novel | 490 | Y>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA7860957 rs751213072 |
491 | K>T | Variant assessed as Somatic; 4.62e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA7860958 rs201377436 |
492 | C>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1409070500 CA394502950 |
494 | E>D | No |
ClinGen TOPMed |
|
|
CA7860960 rs199582494 |
494 | E>K | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs199582494 CA7860959 |
494 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1288165602 CA394502960 |
496 | G>W | No |
ClinGen gnomAD |
|
|
CA394502972 CA276931114 rs973064356 |
497 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA394502979 rs199706085 |
498 | I>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA394502981 rs1253123938 |
499 | F>V | No |
ClinGen gnomAD |
|
|
rs1182857552 CA394503013 |
503 | S>F | No |
ClinGen TOPMed |
|
|
rs1379241778 CA394503032 |
506 | L>F | No |
ClinGen gnomAD |
|
|
CA7860963 rs755474014 |
507 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1202685266 CA394503037 |
507 | R>W | No |
ClinGen TOPMed |
|
|
rs757442876 CA276931117 |
508 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774076641 CA276931130 |
510 | R>K | No |
ClinGen Ensembl |
|
|
rs1165514751 CA394503065 |
511 | I>T | No |
ClinGen gnomAD |
|
|
rs746125295 CA7860967 |
513 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA276931139 rs746125295 |
513 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs911000879 CA276931153 |
514 | G>E | No |
ClinGen gnomAD |
|
|
CA276931149 rs986453718 |
514 | G>R | No |
ClinGen Ensembl |
|
|
rs368518042 CA276931171 |
516 | R>* | No |
ClinGen ESP TOPMed |
|
|
rs772324900 CA7860969 |
516 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs780345216 CA7860970 |
517 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA7860971 rs201330046 |
518 | Y>C | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1283170848 CA394503139 |
520 | C>S | No |
ClinGen TOPMed |
|
|
rs777143418 CA7860973 |
521 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860974 rs142452283 |
522 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA7860975 rs142452283 |
522 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA394503175 rs1196134082 |
522 | E>V | No |
ClinGen gnomAD |
|
|
rs915396452 CA276931256 |
524 | G>E | No |
ClinGen Ensembl |
|
|
rs779536061 CA7860976 |
524 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767203438 CA7860978 |
529 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA7860977 rs528204707 |
529 | R>W | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA394503273 rs1428287978 |
530 | S>G | No |
ClinGen Ensembl |
|
|
rs1359329227 CA394503292 |
531 | S>L | No |
ClinGen TOPMed |
|
|
rs752233963 CA7860979 |
532 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394503295 rs1338327730 |
532 | H>Y | No |
ClinGen TOPMed |
|
|
CA7860982 rs34236132 VAR_052802 |
534 | V>I | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA394503363 rs1043065693 |
537 | E>A | No |
ClinGen TOPMed gnomAD |
|
|
CA276931303 rs1043065693 |
537 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
rs765291383 COSM264921 CA7860984 |
537 | E>K | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1397277762 CA394503397 |
540 | H>N | No |
ClinGen gnomAD |
|
|
rs186225306 CA7860987 |
541 | E>K | No |
ClinGen 1000Genomes ExAC |
|
|
rs1332386109 CA394503438 |
542 | R>S | No |
ClinGen gnomAD |
|
|
CA7860988 rs758339410 |
542 | R>T | No |
ClinGen ExAC gnomAD |
|
|
rs780333335 CA394503452 |
543 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7860990 rs747182693 |
544 | R>I | No |
ClinGen ExAC gnomAD |
|
|
rs747182693 CA394503460 |
544 | R>K | No |
ClinGen ExAC gnomAD |
|
| rs763274759 | 545 | L>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA7860991 rs778210681 |
545 | L>F | No |
ClinGen ExAC gnomAD |
|
|
CA276931327 rs778210681 |
545 | L>I | No |
ClinGen ExAC gnomAD |
|
|
CA276931337 rs747202333 |
547 | P>A | No |
ClinGen gnomAD |
|
|
CA394503503 rs1218546188 |
547 | P>R | No |
ClinGen gnomAD |
|
|
CA7860992 rs781516877 |
548 | F>I | No |
ClinGen ExAC gnomAD |
|
|
CA7860993 rs748715975 |
549 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA7860994 rs748715975 |
549 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA394503522 rs1339436553 |
549 | S>P | No |
ClinGen gnomAD |
|
|
rs919339924 CA276931341 |
550 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA394503530 rs1275997132 |
550 | E>K | No |
ClinGen gnomAD |
|
|
CA7860995 rs143512713 |
551 | C>Y | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA276931361 rs1056408748 |
556 | S>T | No |
ClinGen Ensembl |
|
|
CA394503588 rs1325257673 |
558 | S>G | No |
ClinGen gnomAD |
|
|
CA276931368 rs147916892 COSM107698 |
559 | T>I | skin [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
rs929832248 CA276931373 |
560 | P>T | No |
ClinGen TOPMed gnomAD |
|
|
rs771435366 CA7860998 |
561 | F>C | No |
ClinGen ExAC gnomAD |
|
|
CA394503623 rs1567253554 |
562 | L>F | No |
ClinGen Ensembl |
|
|
rs895122062 CA276931378 |
563 | T>I | No |
ClinGen gnomAD |
|
|
CA394503637 rs895122062 |
563 | T>K | No |
ClinGen gnomAD |
|
|
CA7861000 rs760374713 |
566 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1399973255 CA394503709 |
567 | A>T | No |
ClinGen gnomAD |
|
|
CA7861002 rs776553812 |
567 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA394503722 rs1326522190 |
568 | H>D | No |
ClinGen TOPMed gnomAD |
|
|
rs761908255 CA7861003 |
571 | E>Q | No |
ClinGen ExAC |
|
|
rs765220620 CA7861004 |
572 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA394503792 rs1450081269 |
573 | K>N | No |
ClinGen TOPMed |
|
|
rs368879957 CA7861005 |
573 | K>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1346777701 CA394503799 |
574 | L>F | No |
ClinGen gnomAD |
|
|
CA394503812 rs1596373375 |
575 | F>S | No |
ClinGen Ensembl |
|
|
rs1211134917 CA394503824 |
576 | E>A | No |
ClinGen gnomAD |
|
|
rs1487165579 CA394503842 |
577 | C>Y | No |
ClinGen gnomAD |
|
|
CA394503868 rs1320898161 |
579 | T>A | No |
ClinGen TOPMed |
|
|
CA276931428 rs1016981747 |
579 | T>I | No |
ClinGen Ensembl |
|
|
COSM170420 CA7861010 rs781606939 |
585 | R>Q | Variant assessed as Somatic; 0.0 impact. liver large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA7861009 rs138118006 |
585 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs748521824 CA7861011 |
587 | G>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394503994 rs1378885470 |
588 | M>R | No |
ClinGen TOPMed gnomAD |
|
|
CA7861012 rs199882036 |
588 | M>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs373442363 CA7861013 |
589 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
CA394504023 rs1289972831 |
590 | L>F | No |
ClinGen gnomAD |
|
| TCGA novel | 590 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1385584162 CA394504034 |
591 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1385584162 CA394504033 |
591 | T>P | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 595 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA276931479 rs553554211 |
596 | T>A | No |
ClinGen 1000Genomes |
|
|
CA7861016 rs202011828 |
598 | T>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs994009463 CA276931517 |
599 | G>E | No |
ClinGen TOPMed gnomAD |
|
|
CA276931524 rs894152806 |
600 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA394504145 rs894152806 |
600 | E>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1351247656 CA394504168 |
601 | K>N | No |
ClinGen gnomAD |
|
| TCGA novel | 601 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA7861017 rs573207879 |
602 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7861019 rs201180719 |
604 | K>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA7861020 rs201180719 |
604 | K>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1207963342 CA394504229 |
606 | T>A | No |
ClinGen gnomAD |
|
| TCGA novel | 609 | G>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs764888426 CA7861021 |
610 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs773229074 CA7861022 |
611 | N>H | No |
ClinGen ExAC gnomAD |
|
|
rs986684390 CA276931602 |
613 | S>F | No |
ClinGen Ensembl |
|
|
rs1359661008 CA394504365 |
617 | N>S | No |
ClinGen TOPMed |
|
|
CA7861023 rs762765779 |
619 | I>T | No |
ClinGen ExAC |
|
|
rs1236513386 CA394504385 |
619 | I>V | No |
ClinGen gnomAD |
|
|
rs867228359 CA276931635 |
624 | I>T | No |
ClinGen Ensembl |
|
|
CA394504486 rs1365892858 |
626 | T>I | No |
ClinGen gnomAD |
|
|
CA276931643 rs745921615 |
627 | G>V | No |
ClinGen Ensembl |
|
|
CA7861027 rs759549837 |
630 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 634 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA7861030 rs756536911 |
635 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA7861029 rs752870884 |
635 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA7861031 rs777971924 |
636 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs757689322 CA7861033 |
637 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs746518044 CA7861035 |
638 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA7861036 rs768223253 |
639 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA7861037 rs781013086 |
640 | F>C | No |
ClinGen ExAC gnomAD |
|
|
rs1430640945 CA394504715 |
645 | N>H | No |
ClinGen TOPMed |
|
|
CA394504717 rs1215706977 |
645 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA7861039 rs57710602 VAR_061943 COSM3420970 |
646 | R>Q | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated UniProt 1000Genomes ExAC NCI-TCGA TOPMed dbSNP gnomAD |
|
VAR_084704 rs747714553 CA7861038 |
646 | R>W | found in a patient with hypothalamic hamartoma; unknown pathological significance [UniProt] | No |
ClinGen UniProt ExAC TOPMed dbSNP gnomAD |
|
CA7861040 rs772871353 |
647 | I>T | No |
ClinGen ExAC gnomAD |
|
|
COSM140082 rs200550230 CA7861041 |
648 | R>C | skin [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
CA394504732 rs1422387734 |
648 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA7861044 rs759639642 |
651 | R>K | No |
ClinGen ExAC |
|
|
CA394504757 rs924080839 |
652 | T>K | No |
ClinGen TOPMed gnomAD |
|
|
CA276931770 rs924080839 COSM219581 |
652 | T>M | NS [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
rs752960440 CA7861047 |
653 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
CA7861049 rs373512796 COSM703088 |
654 | T>M | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA276931794 rs866182611 |
657 | R>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs1347259892 CA394504796 |
658 | P>L | No |
ClinGen TOPMed |
|
|
CA7861054 rs754565567 |
659 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA394504807 rs1365087848 |
660 | K>R | No |
ClinGen TOPMed |
|
|
rs1306954670 CA394504824 |
662 | S>C | No |
ClinGen gnomAD |
|
|
rs1276433047 CA394504822 |
662 | S>P | No |
ClinGen gnomAD |
|
|
rs1458881780 CA394504835 |
664 | C>R | No |
ClinGen gnomAD |
|
|
rs780816727 CA7861055 |
668 | F>C | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 668 | F>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1463778526 CA394504875 |
669 | S>C | No |
ClinGen TOPMed |
|
|
CA7861057 rs747881323 |
670 | R>L | No |
ClinGen ExAC gnomAD |
|
|
CA7861056 rs747881323 |
670 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA394504877 rs1253237931 |
670 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs375516445 CA7861058 |
672 | S>C | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA276931816 rs895157870 |
673 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs749051794 CA7861059 |
673 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749051794 CA276931823 |
673 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA276931827 rs909727853 |
675 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
rs770664169 CA7861060 |
676 | S>N | No |
ClinGen ExAC gnomAD |
|
|
CA394504921 rs1490038505 |
677 | H>R | No |
ClinGen TOPMed |
|
| TCGA novel | 677 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
COSM970404 rs1427357692 CA394504937 |
679 | R>I | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA7861061 rs768516356 |
680 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA276931828 rs768516356 |
680 | T>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA7861063 rs772191230 |
682 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs1038898486 CA276931839 |
682 | T>R | No |
ClinGen gnomAD |
|
|
rs1055719991 CA276931841 |
684 | G>Y | No |
ClinGen TOPMed gnomAD |
No associated diseases with O14978
5 regional properties for O14978
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SCAN domain | 48 - 160 | IPR003309 |
| domain | Zinc finger C2H2-type | 251 - 278 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 279 - 306 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 307 - 334 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 335 - 362 | IPR013087-4 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
8 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| DNA-binding transcription factor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II. |
| DNA-binding transcription repressor activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II. |
| metal ion binding | Binding to a metal ion. |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
| sequence-specific double-stranded DNA binding | Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
177 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q08DS3 | OSR1 | Protein odd-skipped-related 1 | Bos taurus (Bovine) | PR |
| Q2VWH6 | FEZF2 | Fez family zinc finger protein 2 | Bos taurus (Bovine) | PR |
| A6QNZ0 | ZSCAN26 | Zinc finger and SCAN domain-containing protein 26 | Bos taurus (Bovine) | PR |
| A7MBI1 | ZFP69 | Zinc finger protein 69 homolog | Bos taurus (Bovine) | PR |
| Q08705 | CTCF | Transcriptional repressor CTCF | Gallus gallus (Chicken) | PR |
| O42409 | GFI1B | Zinc finger protein Gfi-1b | Gallus gallus (Chicken) | PR |
| A2T6W2 | ZNF449 | Zinc finger protein 449 | Pan troglodytes (Chimpanzee) | PR |
| Q9U405 | grau | Transcription factor grauzone | Drosophila melanogaster (Fruit fly) | PR |
| Q7K0S9 | sug | Zinc finger protein GLIS2 homolog | Drosophila melanogaster (Fruit fly) | PR |
| P20385 | Cf2 | Chorion transcription factor Cf2 | Drosophila melanogaster (Fruit fly) | PR |
| Q86P48 | ATbp | AT-rich binding protein | Drosophila melanogaster (Fruit fly) | PR |
| P28698 | MZF1 | Myeloid zinc finger 1 | Homo sapiens (Human) | PR |
| Q9NTW7 | ZFP64 | Zinc finger protein 64 | Homo sapiens (Human) | PR |
| P08151 | GLI1 | Zinc finger protein GLI1 | Homo sapiens (Human) | PR |
| Q9UFB7 | ZBTB47 | Zinc finger and BTB domain-containing protein 47 | Homo sapiens (Human) | PR |
| P18146 | EGR1 | Early growth response protein 1 | Homo sapiens (Human) | PR |
| Q9Y5W3 | KLF2 | Krueppel-like factor 2 | Homo sapiens (Human) | PR |
| Q96SZ4 | ZSCAN10 | Zinc finger and SCAN domain-containing protein 10 | Homo sapiens (Human) | PR |
| P57682 | KLF3 | Krueppel-like factor 3 | Homo sapiens (Human) | PR |
| P25490 | YY1 | Transcriptional repressor protein YY1 | Homo sapiens (Human) | SS |
| O43296 | ZNF264 | Zinc finger protein 264 | Homo sapiens (Human) | PR |
| P49711 | CTCF | Transcriptional repressor CTCF | Homo sapiens (Human) | PR |
| Q9NQX1 | PRDM5 | PR domain zinc finger protein 5 | Homo sapiens (Human) | PR |
| Q9HBE1 | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 | Homo sapiens (Human) | PR |
| Q8TAX0 | OSR1 | Protein odd-skipped-related 1 | Homo sapiens (Human) | PR |
| Q8TBJ5 | FEZF2 | Fez family zinc finger protein 2 | Homo sapiens (Human) | PR |
| Q96SR6 | ZNF382 | Zinc finger protein 382 | Homo sapiens (Human) | PR |
| Q9ULJ3 | ZBTB21 | Zinc finger and BTB domain-containing protein 21 | Homo sapiens (Human) | PR |
| O75840 | KLF7 | Krueppel-like factor 7 | Homo sapiens (Human) | PR |
| Q13127 | REST | RE1-silencing transcription factor | Homo sapiens (Human) | PR |
| Q8IZM8 | ZNF654 | Zinc finger protein 654 | Homo sapiens (Human) | PR |
| Q14526 | HIC1 | Hypermethylated in cancer 1 protein | Homo sapiens (Human) | PR |
| Q06889 | EGR3 | Early growth response protein 3 | Homo sapiens (Human) | PR |
| Q08ER8 | ZNF543 | Zinc finger protein 543 | Homo sapiens (Human) | PR |
| Q8N680 | ZBTB2 | Zinc finger and BTB domain-containing protein 2 | Homo sapiens (Human) | PR |
| O95625 | ZBTB11 | Zinc finger and BTB domain-containing protein 11 | Homo sapiens (Human) | PR |
| Q96BV0 | ZNF775 | Zinc finger protein 775 | Homo sapiens (Human) | PR |
| Q5FWF6 | ZNF789 | Zinc finger protein 789 | Homo sapiens (Human) | PR |
| Q05516 | ZBTB16 | Zinc finger and BTB domain-containing protein 16 | Homo sapiens (Human) | PR |
| Q9H116 | GZF1 | GDNF-inducible zinc finger protein 1 | Homo sapiens (Human) | PR |
| Q8IW36 | ZNF695 | Zinc finger protein 695 | Homo sapiens (Human) | PR |
| Q5VTD9 | GFI1B | Zinc finger protein Gfi-1b | Homo sapiens (Human) | PR |
| Q6PG37 | ZNF790 | Zinc finger protein 790 | Homo sapiens (Human) | PR |
| Q9NQV6 | PRDM10 | PR domain zinc finger protein 10 | Homo sapiens (Human) | PR |
| Q9Y2D9 | ZNF652 | Zinc finger protein 652 | Homo sapiens (Human) | PR |
| Q5TC79 | ZBTB37 | Zinc finger and BTB domain-containing protein 37 | Homo sapiens (Human) | PR |
| Q9Y4E5 | ZNF451 | E3 SUMO-protein ligase ZNF451 | Homo sapiens (Human) | PR |
| Q8ND82 | ZNF280C | Zinc finger protein 280C | Homo sapiens (Human) | PR |
| Q49AA0 | ZFP69 | Zinc finger protein 69 homolog | Homo sapiens (Human) | PR |
| O43298 | ZBTB43 | Zinc finger and BTB domain-containing protein 43 | Homo sapiens (Human) | PR |
| Q9Y330 | ZBTB12 | Zinc finger and BTB domain-containing protein 12 | Homo sapiens (Human) | PR |
| Q13105 | ZBTB17 | Zinc finger and BTB domain-containing protein 17 | Homo sapiens (Human) | PR |
| P51508 | ZNF81 | Zinc finger protein 81 | Homo sapiens (Human) | PR |
| Q5JNZ3 | ZNF311 | Zinc finger protein 311 | Homo sapiens (Human) | PR |
| Q9Y4X4 | KLF12 | Krueppel-like factor 12 | Homo sapiens (Human) | PR |
| P10074 | ZBTB48 | Telomere zinc finger-associated protein | Homo sapiens (Human) | PR |
| P17010 | ZFX | Zinc finger X-chromosomal protein | Homo sapiens (Human) | PR |
| Q9H5H4 | ZNF768 | Zinc finger protein 768 | Homo sapiens (Human) | PR |
| Q9Y2L8 | ZKSCAN5 | Zinc finger protein with KRAB and SCAN domains 5 | Homo sapiens (Human) | PR |
| Q86UZ6 | ZBTB46 | Zinc finger and BTB domain-containing protein 46 | Homo sapiens (Human) | PR |
| Q8NCP5 | ZBTB44 | Zinc finger and BTB domain-containing protein 44 | Homo sapiens (Human) | PR |
| P41182 | BCL6 | B-cell lymphoma 6 protein | Homo sapiens (Human) | PR |
| Q9NQX0 | PRDM6 | Putative histone-lysine N-methyltransferase PRDM6 | Homo sapiens (Human) | PR |
| Q9BU19 | ZNF692 | Zinc finger protein 692 | Homo sapiens (Human) | PR |
| Q08AG5 | ZNF844 | Zinc finger protein 844 | Homo sapiens (Human) | PR |
| Q6R2W3 | ZBED9 | SCAN domain-containing protein 3 | Homo sapiens (Human) | PR |
| P98182 | ZNF200 | Zinc finger protein 200 | Homo sapiens (Human) | PR |
| Q9UK11 | ZNF223 | Zinc finger protein 223 | Homo sapiens (Human) | PR |
| O15156 | ZBTB7B | Zinc finger and BTB domain-containing protein 7B | Homo sapiens (Human) | PR |
| Q6ZMS7 | ZNF783 | Zinc finger protein 783 | Homo sapiens (Human) | PR |
| P59923 | ZNF445 | Zinc finger protein 445 | Homo sapiens (Human) | PR |
| Q8N859 | ZNF713 | Zinc finger protein 713 | Homo sapiens (Human) | PR |
| Q99612 | KLF6 | Krueppel-like factor 6 | Homo sapiens (Human) | PR |
| Q8TD17 | ZNF398 | Zinc finger protein 398 | Homo sapiens (Human) | PR |
| P52739 | ZNF131 | Zinc finger protein 131 | Homo sapiens (Human) | PR |
| Q05215 | EGR4 | Early growth response protein 4 | Homo sapiens (Human) | PR |
| Q7Z398 | ZNF550 | Zinc finger protein 550 | Homo sapiens (Human) | PR |
| Q9Y2K1 | ZBTB1 | Zinc finger and BTB domain-containing protein 1 | Homo sapiens (Human) | PR |
| Q96N20 | ZNF75A | Zinc finger protein 75A | Homo sapiens (Human) | PR |
| A1YPR0 | ZBTB7C | Zinc finger and BTB domain-containing protein 7C | Homo sapiens (Human) | PR |
| P24278 | ZBTB25 | Zinc finger and BTB domain-containing protein 25 | Homo sapiens (Human) | PR |
| Q96N38 | ZNF714 | Zinc finger protein 714 | Homo sapiens (Human) | PR |
| Q86YH2 | ZNF280B | Zinc finger protein 280B | Homo sapiens (Human) | PR |
| A6NGD5 | ZSCAN5C | Zinc finger and SCAN domain-containing protein 5C | Homo sapiens (Human) | PR |
| A6NJL1 | ZSCAN5B | Zinc finger and SCAN domain-containing protein 5B | Homo sapiens (Human) | PR |
| P17029 | ZKSCAN1 | Zinc finger protein with KRAB and SCAN domains 1 | Homo sapiens (Human) | PR |
| P49910 | ZNF165 | Zinc finger protein 165 | Homo sapiens (Human) | PR |
| Q86XF7 | ZNF575 | Zinc finger protein 575 | Homo sapiens (Human) | PR |
| Q8NAM6 | ZSCAN4 | Zinc finger and SCAN domain-containing protein 4 | Homo sapiens (Human) | PR |
| Q969J2 | ZKSCAN4 | Zinc finger protein with KRAB and SCAN domains 4 | Homo sapiens (Human) | PR |
| Q9H9D4 | ZNF408 | Zinc finger protein 408 | Homo sapiens (Human) | PR |
| Q9UNY5 | ZNF232 | Zinc finger protein 232 | Homo sapiens (Human) | PR |
| Q9NPC7 | MYNN | Myoneurin | Homo sapiens (Human) | PR |
| P17022 | ZNF18 | Zinc finger protein 18 | Homo sapiens (Human) | PR |
| Q6P9G9 | ZNF449 | Zinc finger protein 449 | Homo sapiens (Human) | PR |
| O60304 | ZNF500 | Zinc finger protein 500 | Homo sapiens (Human) | PR |
| Q9NX65 | ZSCAN32 | Zinc finger and SCAN domain-containing protein 32 | Homo sapiens (Human) | PR |
| Q96IT1 | ZNF496 | Zinc finger protein 496 | Homo sapiens (Human) | PR |
| O14771 | ZNF213 | Zinc finger protein 213 | Homo sapiens (Human) | PR |
| O95125 | ZNF202 | Zinc finger protein 202 | Homo sapiens (Human) | PR |
| Q8IWY8 | ZSCAN29 | Zinc finger and SCAN domain-containing protein 29 | Homo sapiens (Human) | PR |
| Q8N0Y2 | ZNF444 | Zinc finger protein 444 | Homo sapiens (Human) | PR |
| Q8NF99 | ZNF397 | Zinc finger protein 397 | Homo sapiens (Human) | PR |
| Q9NWS9 | ZNF446 | Zinc finger protein 446 | Homo sapiens (Human) | PR |
| Q96N95 | ZNF396 | Zinc finger protein 396 | Homo sapiens (Human) | PR |
| Q9UL58 | ZNF215 | Zinc finger protein 215 | Homo sapiens (Human) | PR |
| Q53GI3 | ZNF394 | Zinc finger protein 394 | Homo sapiens (Human) | PR |
| Q9BRR0 | ZKSCAN3 | Zinc finger protein with KRAB and SCAN domains 3 | Homo sapiens (Human) | PR |
| Q6NSZ9 | ZSCAN25 | Zinc finger and SCAN domain-containing protein 25 | Homo sapiens (Human) | PR |
| P17028 | ZNF24 | Zinc finger protein 24 | Homo sapiens (Human) | PR |
| Q63HK3 | ZKSCAN2 | Zinc finger protein with KRAB and SCAN domains 2 | Homo sapiens (Human) | PR |
| Q15776 | ZKSCAN8 | Zinc finger protein with KRAB and SCAN domains 8 | Homo sapiens (Human) | PR |
| O08584 | Klf6 | Krueppel-like factor 6 | Mus musculus (Mouse) | PR |
| Q61164 | Ctcf | Transcriptional repressor CTCF | Mus musculus (Mouse) | PR |
| Q810A1 | Znf18 | Zinc finger protein 18 | Mus musculus (Mouse) | PR |
| Q8BGS3 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Mus musculus (Mouse) | PR |
| Q00899 | Yy1 | Transcriptional repressor protein YY1 | Mus musculus (Mouse) | PR |
| P41183 | Bcl6 | B-cell lymphoma 6 protein homolog | Mus musculus (Mouse) | PR |
| Q9DAI4 | Zbtb43 | Zinc finger and BTB domain-containing protein 43 | Mus musculus (Mouse) | PR |
| O70237 | Gfi1b | Zinc finger protein Gfi-1b | Mus musculus (Mouse) | PR |
| Q99KZ6 | Znf639 | Zinc finger protein 639 | Mus musculus (Mouse) | PR |
| Q9Z1D9 | Znf394 | Zinc finger protein 394 | Mus musculus (Mouse) | PR |
| Q9CXE0 | Prdm5 | PR domain zinc finger protein 5 | Mus musculus (Mouse) | PR |
| P43300 | Egr3 | Early growth response protein 3 | Mus musculus (Mouse) | PR |
| Q9DAU9 | Znf654 | Zinc finger protein 654 | Mus musculus (Mouse) | PR |
| Q9R1Y5 | Hic1 | Hypermethylated in cancer 1 protein | Mus musculus (Mouse) | PR |
| Q8R0T2 | Znf768 | Zinc finger protein 768 | Mus musculus (Mouse) | PR |
| Q9WVG7 | Osr1 | Protein odd-skipped-related 1 | Mus musculus (Mouse) | PR |
| Q8BI73 | Znf775 | Zinc finger protein 775 | Mus musculus (Mouse) | PR |
| Q8VCZ7 | Zbtb7c | Zinc finger and BTB domain-containing protein 7C | Mus musculus (Mouse) | PR |
| Q91VN1 | Znf24 | Zinc finger protein 24 | Mus musculus (Mouse) | PR |
| Q9DB38 | Znf580 | Zinc finger protein 580 | Mus musculus (Mouse) | PR |
| A7KBS4 | Zscan4d | Zinc finger and SCAN domain containing protein 4D | Mus musculus (Mouse) | PR |
| Q91VW9 | Zkscan3 | Zinc finger protein with KRAB and SCAN domains 3 | Mus musculus (Mouse) | PR |
| P10925 | Zfy1 | Zinc finger Y-chromosomal protein 1 | Mus musculus (Mouse) | PR |
| P08046 | Egr1 | Early growth response protein 1 | Mus musculus (Mouse) | PR |
| Q3TTC2 | Yy2 | Transcription factor YY2 | Mus musculus (Mouse) | PR |
| Q3UTQ7 | Prdm10 | PR domain zinc finger protein 10 | Mus musculus (Mouse) | PR |
| Q6P3Y5 | Znf280c | Zinc finger protein 280C | Mus musculus (Mouse) | PR |
| Q9ERU3 | Znf22 | Zinc finger protein 22 | Mus musculus (Mouse) | PR |
| Q8VIG1 | Rest | RE1-silencing transcription factor | Mus musculus (Mouse) | PR |
| Q9Z1D8 | Zkscan5 | Zinc finger protein with KRAB and SCAN domains 5 | Mus musculus (Mouse) | PR |
| Q8BID6 | Zbtb46 | Zinc finger and BTB domain-containing protein 46 | Mus musculus (Mouse) | PR |
| P17012 | Zfx | Zinc finger X-chromosomal protein | Mus musculus (Mouse) | PR |
| Q9WUK6 | Zbtb18 | Zinc finger and BTB domain-containing protein 18 | Mus musculus (Mouse) | PR |
| O35738 | Klf12 | Krueppel-like factor 12 | Mus musculus (Mouse) | PR |
| B2RXC5 | Znf382 | Zinc finger protein 382 | Mus musculus (Mouse) | PR |
| O08900 | Ikzf3 | Zinc finger protein Aiolos | Mus musculus (Mouse) | PR |
| Q5DU09 | Znf652 | Zinc finger protein 652 | Mus musculus (Mouse) | PR |
| Q5RJ54 | Zscan26 | Zinc finger and SCAN domain-containing protein 26 | Mus musculus (Mouse) | PR |
| Q8BLM0 | Klf8 | Krueppel-like factor 8 | Mus musculus (Mouse) | PR |
| Q99JB0 | Klf7 | Krueppel-like factor 7 | Mus musculus (Mouse) | PR |
| Q8R0A2 | Zbtb44 | Zinc finger and BTB domain-containing protein 44 | Mus musculus (Mouse) | PR |
| P20662 | Zfy2 | Zinc finger Y-chromosomal protein 2 | Mus musculus (Mouse) | PR |
| Q80VJ6 | Zscan4c | Zinc finger and SCAN domain containing protein 4C | Mus musculus (Mouse) | PR |
| Q3URS2 | Zscan4f | Zinc finger and SCAN domain containing protein 4F | Mus musculus (Mouse) | PR |
| Q60980 | Klf3 | Krueppel-like factor 3 | Mus musculus (Mouse) | PR |
| Q8K3J5 | Znf131 | Zinc finger protein 131 | Mus musculus (Mouse) | PR |
| Q9Z2K3 | Znf394 | Zinc finger protein 394 | Rattus norvegicus (Rat) | PR |
| Q642B9 | Znf18 | Zinc finger protein 18 | Rattus norvegicus (Rat) | PR |
| B0K011 | Osr1 | Protein odd-skipped-related 1 | Rattus norvegicus (Rat) | PR |
| D3ZUU2 | Gzf1 | GDNF-inducible zinc finger protein 1 | Rattus norvegicus (Rat) | PR |
| B1WBU4 | Zbtb8a | Zinc finger and BTB domain-containing protein 8A | Rattus norvegicus (Rat) | PR |
| Q7TNK3 | Znf24 | Zinc finger protein 24 | Rattus norvegicus (Rat) | PR |
| O35819 | Klf6 | Krueppel-like factor 6 | Rattus norvegicus (Rat) | PR |
| Q9R1D1 | Ctcf | Transcriptional repressor CTCF | Rattus norvegicus (Rat) | PR |
| P43301 | Egr3 | Early growth response protein 3 | Rattus norvegicus (Rat) | PR |
| P08154 | Egr1 | Early growth response protein 1 | Rattus norvegicus (Rat) | PR |
| A0JPL0 | Znf382 | Zinc finger protein 382 | Rattus norvegicus (Rat) | PR |
| Q4KLI1 | Zkscan1 | Zinc finger protein with KRAB and SCAN domains 1 | Rattus norvegicus (Rat) | PR |
| A1L1J6 | Znf652 | Zinc finger protein 652 | Rattus norvegicus (Rat) | PR |
| Q9SHD0 | ZAT4 | Zinc finger protein ZAT4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0P4X6 | zbtb44 | Zinc finger and BTB domain-containing protein 44 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| A4II20 | egr1 | Early growth response protein 1 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q6P882 | zbtb8a.2 | Zinc finger and BTB domain-containing protein 8A.2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| Q567C6 | znf367 | Zinc finger protein 367 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| A7Y7X5 | znf711 | Zinc finger protein 711 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASGPGSQER | EGLLIVKLEE | DCAWSQELPP | PDPGPSPEAS | HLRFRRFRFQ | EAAGPREALS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RLQELCHGWL | RPEMRTKEQI | LELLVLEQFL | TILPQEIQSR | VQELHPESGE | EAVTLVEDMQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RELGRLRQQV | TNHGRGTEVL | LEEPLPLETA | RESPSFKLEP | METERSPGPR | LQELLGPSPQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RDPQAVKERA | LSAPWLSLFP | PEGNMEDKEM | TGPQLPESLE | DVAMYISQEE | WGHQDPSKRA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSRDTVQESY | ENVDSLESHI | PSQEVPGTQV | GQGGKLWDPS | VQSCKEGLSP | RGPAPGEEKF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ENLEGVPSVC | SENIHPQVLL | PDQARGEVPW | SPELGRPHDR | SQGDWAPPPE | GGMEQALAGA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SSGRELGRPK | ELQPKKLHLC | PLCGKNFSNN | SNLIRHQRIH | AAERLCMGVD | CTEIFGGNPR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FLSLHRAHLG | EEAHKCLECG | KCFSQNTHLT | RHQRTHTGEK | PYQCNICGKC | FSCNSNLHRH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QRTHTGEKPY | KCPECGEIFA | HSSNLLRHQR | IHTGERPYKC | PECGKSFSRS | SHLVIHERTH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ERERLYPFSE | CGEAVSDSTP | FLTNHGAHKA | EKKLFECLTC | GKSFRQGMHL | TRHQRTHTGE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KPYKCTLCGE | NFSHRSNLIR | HQRIHTGEKP | YTCHECGDSF | SHSSNRIRHL | RTHTGERPYK |
| 670 | 680 | ||||
| CSECGESFSR | SSRLMSHQRT | HTG |