O08602

PR
Gene name
Raet1a
Protein name
Retinoic acid early-inducible protein 1-alpha
Names
RAE-1-alpha
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:19368
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

170-253 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O08602

Entry ID Method Resolution Chain Position Source
AF-O08602-F1 Predicted AlphaFoldDB

No variants for O08602

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O08602

No associated diseases with O08602

1 regional properties for O08602

Type Name Position InterPro Accession
domain Retinoic acid early-inducible protein 1 31 - 204 IPR029287

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor, GPI-anchor
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
anchored component of plasma membrane The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
external side of plasma membrane The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
natural killer cell lectin-like receptor binding Binding to a lectin-like natural killer cell receptor.

3 GO annotations of biological process

Name Definition
cellular response to exogenous dsRNA Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
cellular response to lipopolysaccharide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q61559 Fcgrt IgG receptor FcRn large subunit p51 Mus musculus (Mouse) PR
10 20 30 40 50 60
MAKAAVTKRH HFMIQKLLIL LSYGYTNGLD DAHSLRCNLT IKDPTPADPL WYEAKCLVDE
70 80 90 100 110 120
ILILHLSNIN KTMTSGDPGE TANATEVGEC LTQPLKDLCQ KLRNKVSNTK VDTHKTNGYP
130 140 150 160 170 180
HLQVTMIYLQ SQGQIPSATW EFNISDSYFF TFYTENMSWR SANDESGVIM NKWKDDGEFV
190 200 210 220 230 240
KRLKFLIPEC RQEVDEFLKQ PKEKPRSTSR SPSITQLTST SPLPPPSHST SKKGFISVGL
250
IFISLLFAFA FAM