Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O07522

Entry ID Method Resolution Chain Position Source
AF-O07522-F1 Predicted AlphaFoldDB

No variants for O07522

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O07522

No associated diseases with O07522

2 regional properties for O07522

Type Name Position InterPro Accession
domain Calcineurin-like phosphoesterase domain, ApaH type 6 - 203 IPR004843
domain Mre11 nuclease, N-terminal metallophosphatase domain 7 - 225 IPR041796

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
exodeoxyribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLTDLTFIHA ADLHLDSPFY GISHLPEPIF ARIKESTFAS VRHMIDAAVR EHVDFILLAG
70 80 90 100 110 120
DLFDEANRSL KAQLFLKKQF ERLRECGISV YVIFGNHDHL GGEWTPIEWP ENVHIFSSAV
130 140 150 160 170 180
PEEKSFFKEG RRIASIYGFS YQARALMENQ AARYRRSTDA PFHIGMLHGT LSGSEGHDPY
190 200 210 220 230 240
CPFTHDDLVK SGMDYWALGH IHKRQVLSAE HPAVIYPGNT QARHIKETGD KGYYLVHVTN
250 260 270 280 290 300
GDISYEFQRA HDVLWEKAAV DVTEAKNMTA LFQMVEDTFS KLRKKGSPVC VRLVLQGTAP
310 320 330 340 350 360
EWLLEAPKGT LDEFLEALQE QEAEEERFVW PLRLDDETEN EANLTNLDPF FGGLFEDIDR
370 380 390 400
SDLSDVLEGL ERHPVYRRHA DRFSQEEVKE IKEQAQIILK RQLKVLDT