O02326
Gene name |
cfi-1 (T23D8.8) |
Protein name |
AT-rich interactive domain-containing protein cfi-1 |
Names |
ARID domain-containing protein CFI-1 |
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_T23D8.8 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O02326
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O02326-F1 | Predicted | AlphaFoldDB |
No variants for O02326
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O02326 | |||||
No associated diseases with O02326
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cell fate commitment | The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. |
| cell fate specification | The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. |
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| neuron differentiation | The process in which a relatively unspecialized cell acquires specialized features of a neuron. |
| positive regulation of transcription by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q99856 | ARID3A | AT-rich interactive domain-containing protein 3A | Homo sapiens (Human) | SS |
| Q8BM75 | Arid5b | AT-rich interactive domain-containing protein 5B | Mus musculus (Mouse) | PR |
| Q62431 | Arid3a | AT-rich interactive domain-containing protein 3A | Mus musculus (Mouse) | PR |
| C0SUW7 | ARID6 | AT-rich interactive domain-containing protein 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q0WNR6 | ARID5 | AT-rich interactive domain-containing protein 5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVRIDEPQL | FVSMSKEPTQ | ETVNVGGHHD | DSSSNCDERV | DDQTEEQKSP | PASPDLTANL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NVFDLESRQK | VVQRLLNSQL | NLSNLRAPLN | LPPIFQALQG | PFSIQQQLLG | LASGLTAISP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GLDDYDEENT | NQGEPEDLTL | GGFRKETSVK | SEEPSESGIN | ASGPAWSYEE | QFKQLYELSD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DVKRKEWLDD | WLNFMHRIGK | PVTRIPIMAK | QVLDLYELYR | LVVQHGGLVE | IINKKLWREI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TKGLNLPSSI | TSAAFTLRTQ | YQKYLYDYEC | EKEKLSNQSD | LQQAIDGNRR | EAPGRRTAPS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FPLPFQLPHA | ASAAATMLNN | QLNGLGMRND | LLDDENTLSL | QASGLFGTSY | GAEQMAILEA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HQRNLERAQR | AVQQQVARQS | LGLTACSNGN | GGNIHNSGRE | STSSNDSDIP | AKRPKLENDV |
| 430 | 440 | 450 | 460 | ||
| KTNGASSMRI | STKHSDNSKT | SMSVSMEING | ITYQGVLFAL | DETVSES |