AiPD: Autoinhibited Protein Database

Gene name	RVE2 (CIR1, At5g37260, MNJ8.4)
Protein name	Protein REVEILLE 2
Names	MYB family transcription factor Circadian 1
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT5G37260
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-287 (Predicted disordered autoinhibitory region) PR

1-287 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-F4K5X6-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH12075546	60	R>Q	No	1000Genomes
tmp_5_14752096_C_T	66	G>E	No	1000Genomes
tmp_5_14751939_A_C	90	V>G	No	1000Genomes
tmp_5_14751864_A_G	115	V>A	No	1000Genomes
tmp_5_14751820_A_T	130	S>T	No	1000Genomes
tmp_5_14751816_T_A	131	K>M	No	1000Genomes
ENSVATH12075540	139	R>Q	No	1000Genomes
ENSVATH07236123	178	L>P	No	1000Genomes
tmp_5_14751673_C_T	179	E>K	No	1000Genomes
ENSVATH07236122	198	Y>N	No	1000Genomes
ENSVATH12075539	206	D>G	No	1000Genomes
tmp_5_14751585_T_A	208	E>V	No	1000Genomes
tmp_5_14751544_G_T	222	Q>K	No	1000Genomes
tmp_5_14751534_G_A	225	S>F	No	1000Genomes
tmp_5_14751531_G_A	226	S>F	No	1000Genomes
ENSVATH00679493	231	A>D	No	1000Genomes
tmp_5_14751480_C_G	243	S>T	No	1000Genomes
tmp_5_14751447_G_A	254	S>L	No	1000Genomes
ENSVATH12075538	261	M>L	No	1000Genomes
ENSVATH12075537	268	K>N	No	1000Genomes
tmp_5_14751391_C_A	273	V>L	No	1000Genomes
ENSVATH12075444	282	L>F	No	1000Genomes
ENSVATH07236118	286	L>S	No	1000Genomes
tmp_5_14751349_A_T	287	W>R	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	SANT/Myb domain	31 - 83	IPR001005
domain	Myb domain, plants	34 - 83	IPR006447
domain	SANT domain	34 - 85	IPR017884
domain	Myb domain	31 - 85	IPR017930

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

Name	Definition
circadian rhythm	Any biological process in an organism that recurs with a regularity of approximately 24 hours.
regulation of DNA-templated transcription	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
regulation of flower development	Any process that modulates the frequency, rate or extent of flower development.
seed germination	The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q99543	DNAJC2	DnaJ homolog subfamily C member 2	Homo sapiens (Human)	PR
P54103	Dnajc2	DnaJ homolog subfamily C member 2	Mus musculus (Mouse)	PR
Q7TQ20	Dnajc2	DnaJ homolog subfamily C member 2	Rattus norvegicus (Rat)	PR
P34454	F54F2.9	Uncharacterized protein F54F2.9	Caenorhabditis elegans	PR
F4KGY6	RVE1	Protein REVEILLE 1	Arabidopsis thaliana (Mouse-ear cress)	PR
Q6NWJ4	dnajc2	DnaJ homolog subfamily C member 2	Danio rerio (Zebrafish) (Brachydanio rerio)	PR