Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for F4J4P8

Entry ID Method Resolution Chain Position Source
AF-F4J4P8-F1 Predicted AlphaFoldDB

49 variants for F4J4P8

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH12817727 8 L>F No 1000Genomes
ENSVATH12817726 15 W>R No 1000Genomes
ENSVATH06337379 17 I>F No 1000Genomes
ENSVATH12817725 24 G>* No 1000Genomes
ENSVATH12817725 24 G>R No 1000Genomes
ENSVATH06337378 31 D>E No 1000Genomes
ENSVATH06337373 40 W>* No 1000Genomes
ENSVATH00425794 41 R>H No 1000Genomes
tmp_3_21566214_G_T 44 A>D No 1000Genomes
tmp_3_21566215_C_T 44 A>T No 1000Genomes
tmp_3_21566212_A_G 45 Y>H No 1000Genomes
ENSVATH12817714 48 G>E No 1000Genomes
tmp_3_21566196_C_A 50 R>M No 1000Genomes
ENSVATH06337372 68 P>L No 1000Genomes
ENSVATH00425793 85 N>D No 1000Genomes
tmp_3_21566090_A_C 85 N>K No 1000Genomes
tmp_3_21566074_G_A 91 Q>* No 1000Genomes
tmp_3_21565938_A_T 97 N>K No 1000Genomes
tmp_3_21565918_G_T 104 T>N No 1000Genomes
ENSVATH12817710 112 M>I No 1000Genomes
tmp_3_21565889_G_A 114 R>C No 1000Genomes
ENSVATH02520906 114 R>P No 1000Genomes
ENSVATH06337370 126 V>L No 1000Genomes
tmp_3_21565334_T_C 159 N>D No 1000Genomes
ENSVATH06337363 167 T>I No 1000Genomes
ENSVATH00425790 170 I>V No 1000Genomes
ENSVATH09450244 181 T>A No 1000Genomes
ENSVATH09450243 181 T>K No 1000Genomes
ENSVATH09450242 182 L>F No 1000Genomes
ENSVATH06337361 184 S>R No 1000Genomes
ENSVATH06337360 186 I>M No 1000Genomes
ENSVATH06337359 187 L>* No 1000Genomes
ENSVATH09450241 193 I>T No 1000Genomes
ENSVATH09450239 195 L>I No 1000Genomes
ENSVATH09450237 198 N>H No 1000Genomes
ENSVATH12817669 198 N>S No 1000Genomes
ENSVATH06337356 202 R>* No 1000Genomes
ENSVATH02520899 202 R>Q No 1000Genomes
ENSVATH02520897 213 I>L No 1000Genomes
ENSVATH02520895 234 A>E No 1000Genomes
ENSVATH02520894 235 D>G No 1000Genomes
ENSVATH12817667 245 G>S No 1000Genomes
ENSVATH02520891 252 D>E No 1000Genomes
ENSVATH02520890 258 V>E No 1000Genomes
ENSVATH02520888 263 V>L No 1000Genomes
tmp_3_21564829_C_T 264 V>I No 1000Genomes
ENSVATH02520887 269 K>E No 1000Genomes
ENSVATH02520885 292 L>M No 1000Genomes
ENSVATH02520879 311 D>G No 1000Genomes

No associated diseases with F4J4P8

1 regional properties for F4J4P8

Type Name Position InterPro Accession
domain MATH/TRAF domain 10 - 137 IPR002083

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

15 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6IQ16 SPOPL Speckle-type POZ protein-like Homo sapiens (Human) PR
Q6YCH2 Tdpoz4 TD and POZ domain-containing protein 4 Mus musculus (Mouse) PR
Q2M2N2 Spopl Speckle-type POZ protein-like Mus musculus (Mouse) PR
P34371 bath-42 BTB and MATH domain-containing protein 42 Caenorhabditis elegans PR
F4IN32 At2g42460 MATH domain and coiled-coil domain-containing protein At2g42460 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4A0 At3g44790 MATH domain and coiled-coil domain-containing protein At3g44790 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4A1 At3g44800 MATH domain and coiled-coil domain-containing protein At3g44800 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG7 At2g42480 MATH domain and coiled-coil domain-containing protein At2g42480 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSD2 At3g27040 MATH domain and coiled-coil domain-containing protein At3g27040 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2I2 At3g58340 MATH domain and coiled-coil domain-containing protein At3g58340 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2J0 At3g58260 MATH domain and coiled-coil domain-containing protein At3g58260 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2J5 At3g58210 MATH domain and coiled-coil domain-containing protein At3g58210 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUA7 At2g01790 MATH domain and coiled-coil domain-containing protein At2g01790 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG4 At2g42465 MATH domain and coiled-coil domain-containing protein At2g42465 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SHT3 At2g05410 MATH domain and coiled-coil domain-containing protein At2g05410 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGRIGSPLGK NEFSWVIKDF SSLGVRAIYS DEFVIGGCKW RLIAYPMGNR IKKYMSLYVE
70 80 90 100 110 120
VADSKHLPSG WSINTELRME VVNHNLYKPS QQKYRKNLWF DQKTPSWGYK TMIRHSKLSG
130 140 150 160 170 180
EEGFLVSGEV TIVVKIDVYR VFGKIKRNDD GVKSNDSVNK TQQVKETMDI NGFQVLPSQV
190 200 210 220 230 240
TLVSRILKKY PDIALGFNAK NRHLRTACMN VLISLIETLC QSPQELSDED MDEADNALVY
250 260 270 280 290 300
VQDAGFKVDW LDKKLKEVKE KKVVEQTGKT RIQELEEELK EFKQKCLDRE ALLEKEKAKV
310
LAARASLTLD DFV