Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for F4J4A1

Entry ID Method Resolution Chain Position Source
AF-F4J4A1-F1 Predicted AlphaFoldDB

122 variants for F4J4A1

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_16343356_G_T 8 W>C No 1000Genomes
ENSVATH12458991 16 L>F No 1000Genomes
tmp_3_16343384_T_C 18 S>P No 1000Genomes
ENSVATH06216360 19 E>Q No 1000Genomes
ENSVATH06216361 21 I>N No 1000Genomes
ENSVATH06216361 21 I>T No 1000Genomes
ENSVATH06216362 23 S>A No 1000Genomes
ENSVATH02422905 24 D>Y No 1000Genomes
ENSVATH06216363 25 I>K No 1000Genomes
tmp_3_16343411_G_A 27 V>M No 1000Genomes
ENSVATH12458992 30 G>S No 1000Genomes
ENSVATH06216371 33 W>* No 1000Genomes
ENSVATH06216364 33 W>S No 1000Genomes
ENSVATH00398419 36 L>M No 1000Genomes
ENSVATH02422910 43 Q>R No 1000Genomes
ENSVATH12459035 50 L>M No 1000Genomes
tmp_3_16343600_T_C 57 L>S No 1000Genomes
tmp_3_16343626_A_G 66 R>G No 1000Genomes
tmp_3_16343629_C_T 67 R>C No 1000Genomes
ENSVATH06216377 67 R>H No 1000Genomes
ENSVATH06216377 67 R>L No 1000Genomes
ENSVATH00398420 68 I>V No 1000Genomes
ENSVATH06216378 69 R>K No 1000Genomes
ENSVATH12459042 71 R>G No 1000Genomes
ENSVATH14355829 73 T>S No 1000Genomes
ENSVATH06216379 74 V>G No 1000Genomes
tmp_3_16343668_G_A 80 E>K No 1000Genomes
ENSVATH06216385 92 F>S No 1000Genomes
ENSVATH12459070 97 P>S No 1000Genomes
tmp_3_16343814_T_A 99 C>S No 1000Genomes
ENSVATH06216386 99 C>Y No 1000Genomes
tmp_3_16343842_C_A 108 T>N No 1000Genomes
ENSVATH06216387 110 L>F No 1000Genomes
tmp_3_16343851_A_T 111 N>I No 1000Genomes
ENSVATH02422913 114 H>D No 1000Genomes
ENSVATH06216388 119 V>E No 1000Genomes
ENSVATH02422914 120 N>S No 1000Genomes
ENSVATH02422915 124 K>R No 1000Genomes
ENSVATH06216389 129 V>L No 1000Genomes
ENSVATH06216390 130 D>N No 1000Genomes
ENSVATH02422917 133 E>* No 1000Genomes
ENSVATH02422917 133 E>Q No 1000Genomes
tmp_3_16343922_A_C,G 135 I>L No 1000Genomes
tmp_3_16343922_A_C,G 135 I>V No 1000Genomes
tmp_3_16343925_G_A 136 G>S No 1000Genomes
tmp_3_16343928_A_G 137 K>E No 1000Genomes
tmp_3_16343929_A_G 137 K>R No 1000Genomes
tmp_3_16343931_T_G 138 L>V No 1000Genomes
ENSVATH06216392 144 S>F No 1000Genomes
tmp_3_16343964_A_G 149 K>E No 1000Genomes
ENSVATH06216393 155 R>K No 1000Genomes
ENSVATH12459072 159 D>Y No 1000Genomes
ENSVATH12459074 162 A>V No 1000Genomes
ENSVATH06216395 165 S>N No 1000Genomes
tmp_3_16344015_C_G 166 H>D No 1000Genomes
ENSVATH02422920 168 H>Q No 1000Genomes
ENSVATH06216396 176 V>A No 1000Genomes
tmp_3_16344049_A_G 177 N>S No 1000Genomes
ENSVATH06216397 178 G>R No 1000Genomes
tmp_3_16344067_C_T 183 P>L No 1000Genomes
ENSVATH02422923 184 S>P No 1000Genomes
ENSVATH09427793 191 R>S No 1000Genomes
ENSVATH14355876 192 I>K No 1000Genomes
ENSVATH14355876 192 I>T No 1000Genomes
ENSVATH08133293 195 R>K No 1000Genomes
ENSVATH02422943 198 Y>* No 1000Genomes
ENSVATH09427795 198 Y>D No 1000Genomes
ENSVATH09427797 201 L>V No 1000Genomes
ENSVATH09427798 202 E>K No 1000Genomes
ENSVATH06216407 205 A>T No 1000Genomes
tmp_3_16344421_A_G 206 K>E No 1000Genomes
ENSVATH06216408 209 Q>H No 1000Genomes
ENSVATH06216409 210 L>M No 1000Genomes
ENSVATH00398424 212 A>T No 1000Genomes
ENSVATH06216411 213 S>A No 1000Genomes
ENSVATH06216411 213 S>P No 1000Genomes
tmp_3_16344446_G_C 214 C>S No 1000Genomes
ENSVATH12459165 220 S>N No 1000Genomes
tmp_3_16344467_T_G 221 L>R No 1000Genomes
tmp_3_16344472_AAG_GAG,A 223 K>E No 1000Genomes
tmp_3_16344478_T_A 225 L>M No 1000Genomes
tmp_3_16344484_C_A,G 227 Q>E No 1000Genomes
tmp_3_16344484_C_A,G 227 Q>K No 1000Genomes
tmp_3_16344485_A_T 227 Q>L No 1000Genomes
ENSVATH06216413 228 S>L No 1000Genomes
ENSVATH02422947 231 D>E No 1000Genomes
tmp_3_16344514_C_G 237 L>V No 1000Genomes
tmp_3_16344523_A_G 240 T>A No 1000Genomes
ENSVATH02422949 242 Q>E No 1000Genomes
ENSVATH12459167 243 V>A No 1000Genomes
tmp_3_16344542_T_A 246 F>Y No 1000Genomes
tmp_3_16344549_A_C 248 Q>H No 1000Genomes
tmp_3_16344547_CA_AA,C 248 Q>K No 1000Genomes
ENSVATH12459170 250 S>C No 1000Genomes
ENSVATH12459172 259 R>S No 1000Genomes
ENSVATH12459173 260 K>Q No 1000Genomes
ENSVATH12459174 260 K>R No 1000Genomes
ENSVATH12459185 265 K>T No 1000Genomes
ENSVATH02422950 269 I>M No 1000Genomes
ENSVATH02422951 270 Q>E No 1000Genomes
ENSVATH12459188 271 E>V No 1000Genomes
ENSVATH02422952 272 H>Y No 1000Genomes
ENSVATH12459189 274 G>D No 1000Genomes
tmp_3_16344639_G_C 278 M>I No 1000Genomes
ENSVATH02422954 280 G>E No 1000Genomes
tmp_3_16344658_C_G 285 L>V No 1000Genomes
ENSVATH02422956 290 K>Q No 1000Genomes
ENSVATH08133294 292 C>* No 1000Genomes
ENSVATH02422957 294 D>E No 1000Genomes
ENSVATH02422960 304 E>D No 1000Genomes
ENSVATH06216415 304 E>K No 1000Genomes
tmp_3_16344721_C_T 306 L>F No 1000Genomes
ENSVATH02422961 308 G>E No 1000Genomes
ENSVATH02422963 311 Q>K No 1000Genomes
tmp_3_16344743_G_T 313 C>F No 1000Genomes
ENSVATH02422966 316 I>T No 1000Genomes
tmp_3_16344757_G_A 318 A>T No 1000Genomes
tmp_3_16344779_G_C 325 G>A No 1000Genomes
tmp_3_16344778_G_A 325 G>R No 1000Genomes
tmp_3_16344803_G_C 333 R>T No 1000Genomes
tmp_3_16344806_C_G 334 T>S No 1000Genomes
tmp_3_16344811_C_G 336 L>V No 1000Genomes

No associated diseases with F4J4A1

1 regional properties for F4J4A1

Type Name Position InterPro Accession
domain MATH/TRAF domain 7 - 134 IPR002083

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

15 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6IQ16 SPOPL Speckle-type POZ protein-like Homo sapiens (Human) PR
Q6YCH2 Tdpoz4 TD and POZ domain-containing protein 4 Mus musculus (Mouse) PR
Q2M2N2 Spopl Speckle-type POZ protein-like Mus musculus (Mouse) PR
P34371 bath-42 BTB and MATH domain-containing protein 42 Caenorhabditis elegans PR
F4IN32 At2g42460 MATH domain and coiled-coil domain-containing protein At2g42460 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4A0 At3g44790 MATH domain and coiled-coil domain-containing protein At3g44790 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG7 At2g42480 MATH domain and coiled-coil domain-containing protein At2g42480 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSD2 At3g27040 MATH domain and coiled-coil domain-containing protein At3g27040 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2I2 At3g58340 MATH domain and coiled-coil domain-containing protein At3g58340 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2J0 At3g58260 MATH domain and coiled-coil domain-containing protein At3g58260 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2J5 At3g58210 MATH domain and coiled-coil domain-containing protein At3g58210 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUA7 At2g01790 MATH domain and coiled-coil domain-containing protein At2g01790 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG4 At2g42465 MATH domain and coiled-coil domain-containing protein At2g42465 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SHT3 At2g05410 MATH domain and coiled-coil domain-containing protein At2g05410 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4P8 At3g58220 MATH domain and coiled-coil domain-containing protein At3g58220 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGYEKFTWVI KNFSSLQSEY IKSDIFVIGG CKWCLLAYPN GKQNASYLSL YLDGPTLKTL
70 80 90 100 110 120
PCGCRRRIRF RLTVVNQLSE NLSRRGEGKR WFDKKLPLCG YEEVLLLTKL NAKHGGFLVN
130 140 150 160 170 180
NEVKIVAEVD VLEVIGKLDV SKESQEVIKP RKRMRLYGDG GAVSSHLHKE TSSVDVNGFQ
190 200 210 220 230 240
VLPSQAESVK RIFERHPYMA LEFRAKNQQL RASCINVLLS LIKTLCQSLQ DISIDDLGQT
250 260 270 280 290 300
EQVLTFLQNS GFKVDWLERK LEEVKEKKIQ EHIGKSRMQG LEEDLKVFKK KCSDIEALLE
310 320 330 340
KEKEELKGLK QKCSDIEALL EKEKGKVLAA AARTPLTFDD IL