A9W590

PR
Gene name
yidC
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Methylorubrum extorquens (strain PA1) (Methylobacterium extorquens)
KEGG Pathway
mex:Mext_2351
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

13-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9W590

Entry ID Method Resolution Chain Position Source
AF-A9W590-F1 Predicted AlphaFoldDB

No variants for A9W590

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9W590

No associated diseases with A9W590

3 regional properties for A9W590

Type Name Position InterPro Accession
domain Membrane insertase YidC, N-terminal 7 - 388 IPR028053
domain Membrane insertase YidC/Oxa/ALB, C-terminal 389 - 589 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 391 - 589 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGNDKTNMFV AIALSLVVLL GWHYFVTGPA SERQRQAAQS QTAQTGAPQT ADGIPSPSPR
70 80 90 100 110 120
EGGPNAPAPG TLPGAAAQGP VSREDALARS ARVRIDTPAL YGSIGLKGAR IDDVSLKNYH
130 140 150 160 170 180
ETVSDESPRI VLLSPTGTAN PYYAEFGWVG ANAGPLPNAD TLWKADGDLL APGRPLTLTW
190 200 210 220 230 240
DNGQGLVFKR IVAVDDKFMF TVRDEVENTS ANPVTLYPYS LVSRWGKPQT QGYYVLHEGL
250 260 270 280 290 300
IGVLGGDGLQ EYTYDKVGKE PAYGGAATQG KAWTNVTGGW VGITDKYWAA AAIPEQDKPF
310 320 330 340 350 360
TGAFTERTDG ATKIYQTSVR GDAVTLAPNA SSVTTQRLFA GAKEVNQINA YEREFGIKQF
370 380 390 400 410 420
DLMIDWGWFW FLTKPMFRAL DFFFHLLGNF GVSILLVTLI LKLFFLPIAN RSYVSMAKMK
430 440 450 460 470 480
AVQPEMTSIR ERYKDDRVKQ QQAMMELYKK EKINPVAGCW PVLIQIPVFF ALYKVLFITI
490 500 510 520 530 540
EMRHAPFFGW IQDLAAPDPT SIVNLFGLLP FTPPEYIPIH LGVWPIIMGI TMFIQMKMNP
550 560 570 580 590 600
APPDPVQAQV FAFMPIVFTF MLGSFPAGLV IYWAWNNTLS VIQQYVIMRR NGVKVELWDN
610
LRGMFKRGNK SAAAKG