A7ZPL3

PR
Gene name
zipA
Protein name
Cell division protein ZipA
Names
Species
Escherichia coli O139:H28 (strain E24377A / ETEC)
KEGG Pathway
ecw:EcE24377A_2699
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-216 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A7ZPL3

Entry ID Method Resolution Chain Position Source
AF-A7ZPL3-F1 Predicted AlphaFoldDB

No variants for A7ZPL3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A7ZPL3

No associated diseases with A7ZPL3

8 regional properties for A7ZPL3

Type Name Position InterPro Accession
domain Cyclic nucleotide-binding domain 137 - 253 IPR000595-1
domain Cyclic nucleotide-binding domain 255 - 376 IPR000595-2
domain cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 25 - 62 IPR003117
conserved_site Cyclic nucleotide-binding, conserved site 164 - 180 IPR018488-1
conserved_site Cyclic nucleotide-binding, conserved site 200 - 217 IPR018488-2
conserved_site Cyclic nucleotide-binding, conserved site 282 - 298 IPR018488-3
conserved_site Cyclic nucleotide-binding, conserved site 324 - 341 IPR018488-4
domain RIbeta, dimerization/docking domain 10 - 64 IPR042818

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass type I membrane protein
  • Localizes to the Z ring in an FtsZ-dependent manner
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cell septum assembly The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMQDLRLILI IVGAIAIIAF LVHGFWTSRK ERSSMFRDRP LKRMKSKRDD DSYDEDVEDD
70 80 90 100 110 120
EGVGEVRVHR VNHAPANAQE HEAARPSPQH QYQPPYASAQ PRQPVQQPPE AQVPPQHAPR
130 140 150 160 170 180
PAQPVQQPAY QPQPEQPLQQ PVSPQVAPAP QPVHSAPQPA QQAFQPAEPV AAPQPEPVAE
190 200 210 220 230 240
PAPVMDKPKR KEAVIIMNVA AHHGSELNGE LLLNSIQQAG FIFGDMNIYH RHLSPDGSGP
250 260 270 280 290 300
ALFSLANMVK PGTFDPEMKD FTTPGVTIFM QVPSYGDELQ NFKLMLQSAQ HIADEVGGVV
310 320
LDDQRRMMTP QKLREYQDII REVKDANA